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Number of items: 108.


Abell, K; Bilancio, A; Clarkson, RWE; Tiffen, PG; Altaparmakov, AI; Burdon, TG; Asano, T; (2005) Stat3-induced apoptosis requires a molecular switch in PI(3)K subunit composition. NATURE CELL BIOLOGY , 7 (4) pp. 392-398. 10.1038/ncb1242.

Andy, S; (2005) My dad’s fight with lung cancer. Daily Express pp. 30-31.

Arkenau, H; Kubicka, S; Greil, R; Schmoll, H; Seufferlein, T; Greaven, U; Grothey, A; (2005) Infusional 5-fluorouracil/folinic acid plus oxaliplatin (FUFOX) versus Capecitabine plus oxaliplatin (CAPOX) as first line treatment of metastatic colorectal carcinoma (MCRC): results of the safety and efficacy analysis. EJC SUPPL , 3 (2) 168 - 168.

Arkenau, HT; Müssig, O; Buhr, T; Jend, HH; Porschen, R; (2005) Microangiopathic hemolytic anemia (MAHA) as paraneoplastic syndrome in metastasized signet ring cell carcinomas: case reports and review of the literature. Z Gastroenterol , 43 (8) pp. 719-722. 10.1055/s-2005-858259.

Arkenau, HT; Rettig, K; Porschen, R; (2005) Adjuvant chemotherapy in curative resected colon carcinoma: 5-fluorouracil/leucovorin versus high-dose 5-fluorouracil 24-h infusion/leucovorin versus high-dose 5-fluorouracil 24-h infusion. Int J Colorectal Dis , 20 (3) pp. 258-261. 10.1007/s00384-004-0657-6.

Azzabi, A; Hughes, AN; Calvert, PM; Plummer, ER; Todd, R; Griffin, MJ; Lind, MJ; (2005) Phase I study of temozolomide plus paclitaxel in patients with advanced malignant melanoma and associated in vitro investigations. BRIT J CANCER , 92 (6) 1006 - 1012. 10.1038/sj.bjc.6602438.


BBC, NB; (2005) Lung cancer scientist dies at 92. UNSPECIFIED

BBC, NO; (2005) 'Freeze therapy' for lung cancers. UNSPECIFIED

BBC, NO; (2005) Thalidomide slows cancer disease. UNSPECIFIED

BBC, NO; (2005) Warning to heed lung cancer signs. UNSPECIFIED

Barber, LJ; Ward, TA; Hartley, JA; McHugh, PJ; (2005) DNA interstrand cross-link repair in the Saccharomyces cerevisiae cell cycle: Overlapping roles for PSO2 (SNM1) with MutS factors and EXO1 during S phase. MOL CELL BIOL , 25 (6) 2297 - 2309. 10.1128/MCB.25.6.2297-2309.2005. Gold open access

Beresford, M; Padhani, AR; Goh, V; Makris, A; (2005) Imaging breast cancer response during neoadjuvant systemic therapy. Expert Review of Anticancer Therapy , 5 (5) pp. 893-905.

Bilanges, B; Stokoe, D; (2005) Direct comparison of the specificity of gene silencing using antisense oligonucleotides and RNAi. Biochem J , 388 (Pt 2) pp. 573-583. 10.1042/BJ20041956.

Bilioni, A.; (2005) DNA binding specificities and transcriptional activity of mirror, an Iroquois transcription factor in Drosophila melanogaster. Doctoral thesis, University of London. Green open access

Birtle, AJ; Freeman, A; Masters, JRW; Payne, HA; Harland, SJ; Baus Section Oncology Canc Registr, ; (2005) Tumour markers for managing men who present with metastatic prostate cancer and serum prostate-specific antigen levels of < 10 ng/mL. BJU INT , 96 (3) 303 - 307. 10.1111/j.1464-410X.2005.05619.x.

Boddy, AV; Plummer, ER; Todd, R; Sludden, J; Griffin, M; Robson, L; Cassidy, J; (2005) A phase I and pharmacokinetic study of paclitaxel poliglumex (XYOTAX), investigating both 3-weekly and 2-weekly schedules. CLIN CANCER RES , 11 (21) 7834 - 7840. 10.1158/1078-0432.CCR-05-0803.

Bower, M; Gazzard, B; Mandalia, S; Newsom-Davis, T; Thirlwell, C; Dhillon, T; Young, AM; (2005) A prognostic index for systemic AIDS-related non-Hodgkin lymphoma treated in the era of highly active antiretroviral therapy. ANN INTERN MED , 143 (4) 265 - 273.

Bower, M; Nelson, M; Young, AM; Thirlwell, C; Newsom-Davis, T; Mandalia, S; Dhillon, T; (2005) Immune reconstitution inflammatory syndrome associated with Kaposi's sarcoma. J CLIN ONCOL , 23 (22) 5224 - 5228. 10.1200/JCO.2005.14.597.

Bower, M; Powles, T; Stebbing, J; Thirlwell, C; (2005) Potential antiretroviral drug interactions with cyclophosphamide, doxorubicin, and etoposide. J CLIN ONCOL , 23 (6) 1328 - 1329. 10.1200/JCO.2005.05.128.

Boxer, GM; Tsiompanou, E; Levine, T; Watson, R; Begent, RHJ; (2005) Immunohistochemical expression of vascular endothelial growth factor and microvessel counting as prognostic indicators in node-negative colorectal cancer. TUMOR BIOL , 26 (1) 1 - 8. 10.1159/000084180.

Brandts, CH; Bilanges, B; Hare, G; McCormick, F; Stokoe, D; (2005) Phosphorylation-independent stabilization of p27kip1 by the phosphoinositide 3-kinase pathway in glioblastoma cells. J Biol Chem , 280 (3) pp. 2012-2019. 10.1074/jbc.M408348200.

Braybrooke, JP; Slade, A; Deplanque, G; Harrop, R; Madhusudan, S; Forster, MD; Gibson, R; (2005) Phase I study of MetXia-P450 gene therapy and oral cyclophosphamide for patients with advanced breast cancer or melanoma. Clin Cancer Res , 11 (4) pp. 1512-1520. 10.1158/1078-0432.CCR-04-0155.

Buchmueller, KL; Taherbhai, Z; Howard, CM; Bailey, SL; Nguyen, B; O'Hare, C; Hochhauser, D; (2005) Design of a hairpin polyamide, ZT65B, for targeting the inverted CCAAT box (ICB) site in the multildrug resistant (MDR1) gene. CHEMBIOCHEM , 6 (12) 2305 - 2311. 10.1002/cbic.200500179.


Calvert, AH; (2005) Fishing for new drugs. J CLIN ONCOL , 23 (31) 7780 - 7782. 10.1200/JCO.2005.08.004.

Capponcelli, S; Pedrini, E; Cerone, MA; Corti, V; Fontanesi, S; Alessio, M; Bachi, A; (2005) Evaluation of the molecular mechanisms involved in the gain of function of a Li-Fraumeni TP53 mutation. Hum Mutat , 26 (2) pp. 94-103. 10.1002/humu.20192.

Casely-Hayford, MA; Pors, K; James, CH; Patterson, LH; Hartley, JA; Searcey, M; (2005) Design and synthesis of a DNA-crosslinking azinomycin analogue. ORG BIOMOL CHEM , 3 (19) 3585 - 3589. 10.1039/b508908e.

Cerone, MA; Autexier, C; Londoño-Vallejo, JA; Bacchetti, S; (2005) A human cell line that maintains telomeres in the absence of telomerase and of key markers of ALT. Oncogene , 24 (53) pp. 7893-7901. 10.1038/sj.onc.1208934.

Cerone, MA; Ward, RJ; Londoño-Vallejo, JA; Autexier, C; (2005) Telomerase RNA mutated in autosomal dyskeratosis congenita reconstitutes a weakly active telomerase enzyme defective in telomere elongation. Cell Cycle , 4 (4) pp. 585-589.

Chester, KA; Baker, M; Mayer, A; (2005) Overcoming the immunologic response to foreign enzymes in cancer therapy. Expert Rev Clin Immunol , 1 (4) pp. 549-559. 10.1586/1744666X.1.4.549.

Cheung, CW; Burton, C; Smith, P; Linch, DC; Hoskin, PJ; Ardeshna, KM; (2005) Central nervous system chemoprophylaxis in non-Hodgkin lymphoma: current practice in the UK. BRIT J HAEMATOL , 131 (2) 193 - 200. 10.1111/j.1365-2141.2005.05756.x.

Clingen, PH; De Silva, IU; McHugh, PJ; Ghadessy, FJ; Tilby, MJ; Thurston, DE; Hartley, JA; (2005) The XPF-ERCC1 endonuclease and homologous recon bination contribute to the repair of minor groove DNA interstrand crosslinks in mammalian cells produced by the pyrrolo[2,1-c][1,4]benzodiazepine dimer SJG-136. NUCLEIC ACIDS RES , 33 (10) 3283 - 3291. 10.1093/nar/gki639. Gold open access

Condliffe, AM; Davidson, K; Anderson, KE; Ellson, CD; Crabbe, T; Okkenhaug, K; Vanhaesebroeck, B; (2005) Sequential activation of class IB and class IA PI3K is important for the primed respiratory burst of human but not murine neutrophils. BLOOD , 106 (4) pp. 1432-1440. 10.1182/blood-2005-03-0944.

Corrie, PG; Shaw, J; Spanswick, VJ; Sehmbi, R; Jonson, A; Mayer, A; Bulusu, R; (2005) Phase I trial combining gemcitabine and treosulfan in advanced cutaneous and uveal melanoma patients. BRIT J CANCER , 92 (11) 1997 - 2003. 10.1038/sj.bjc.6602586.

Cutillas, PR; Geering, B; Waterfield, MD; Vanhaesebroeck, B; (2005) Quantification of gel-separated proteins and their phosphorylation sites by LC-MS using unlabeled internal standards: analysis of phosphoprotein dynamics in a B cell lymphoma cell line. Mol Cell Proteomics , 4 (8) pp. 1038-1051. 10.1074/mcp.M500078-MCP200.


Daniell, K; Stewart, M; Madsen, E; Le, M; Handl, H; Brooks, N; Kiakos, K; (2005) Design, synthesis, and biological evaluation of achiral analogs of duocarmycin SA. Bioorg Med Chem Lett , 15 (1) pp. 177-180. 10.1016/j.bmcl.2004.10.021.

Dark, GG; Calvert, AH; Grimshaw, R; Poole, C; Swenerton, K; Kaye, S; Coleman, R; (2005) Randomized trial of two intravenous schedules of the topoisomerase I inhibitor liposomal lurtotecan in women with relapsed epithelial ovarian cancer: A trial of the National Cancer Institute of Canada Clinical Trials Group. JOURNAL OF CLINICAL ONCOLOGY , 23 (9) 1859 - 1866. 10.1200/JCO.2005.02.028.

Dearling, JLJ; Flynn, AA; Beken, L; Petrie, IA; El-Emir, E; Boxer, GM; Green, AJ; (2005) Dose Estimation in a 3D Tumour Reconstruction -Impact of the Heterogeneity of TumourPathophysiology on RIT and EBRT. In: (pp. S83-S83). SPRINGER

Dearling, JLJ; Qureshi, U; Begent, RHJ; Pedley, RB; (2005) Radioimmunotherapy Combined with Anti-Hypoxia Therapy 2DG Results in Reduction of Therapeutic Efficacy. In: (pp. S48-S48). SPRINGER

Dearling, JLJ; Qureshi, U; Whiting, S; Boxer, GM; Begent, RHJ; Pedley, RB; (2005) Analysis of Antibody Distribution Reveals Higher Uptake in Peripheral Intrahepatic Deposits Than Central Deposits. In: (pp. S83-S83). SPRINGER

Deborah, H; (2005) I haven’t smoked for 23 years yet now I face the serves-you-right stigma of this forgotten disease. Evening Standard pp. 27-28.

Dhami, P; Coffey, AJ; Abbs, S; Vermeesch, JR; Dumanski, JP; Woodward, KJ; Andrews, RM; (2005) Exon array CGH: Detection of copy-number changes at the resolution of individual exons in the human genome. AM J HUM GENET , 76 (5) 750 - 762.

de Bruin, EC; van de Pas, S; Lips, EH; van Eijk, R; van der Zee, MM; Lombaerts, M; van Wezel, T; (2005) Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles. BMC Genomics , 6 , Article 142. 10.1186/1471-2164-6-142. Green open access


El-Emir, E; Boxer, GM; Petrie, IA; Boden, RW; Dearling, JLJ; Begent, RHJ; Pedley, RB; (2005) Tumour parameters affected by combretastatin A-4 phosphate therapy in a human colorectal xenograft model in nude mice. EUR J CANCER , 41 (5) 799 - 806. 10.1016/j.ejca.2005.01.001.


Fleenor, D; Oden, J; Kelly, PA; Mohan, S; Alliouachene, S; Pende, M; Wentz, S; (2005) Roles of the lactogens and somatogens in perinatal and postnatal metabolism and growth: studies of a novel mouse model combining lactogen resistance and growth hormone deficiency. Endocrinology , 146 (1) pp. 103-112. 10.1210/en.2004-0744.

Francis, R.J.; (2005) Antibody directed enzyme prodrug therapy - a mechanistic approach. Doctoral thesis, University of London. Green open access


Gibbs, DD; Theti, DS; Wood, N; Green, M; Raynaud, F; Valenti, M; Forster, MD; (2005) BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors. Cancer Res , 65 (24) pp. 11721-11728. 10.1158/0008-5472.CAN-05-2034.

Guest, RD; Hawkins, RE; Kirillova, N; Cheadle, EJ; Arnold, J; O'Neill, A; Irlam, J; (2005) The role of extracellular spacer regions in the optimal design of chimeric immune receptors - Evaluation of four different scFvs and antigens. J IMMUNOTHER , 28 (3) 203 - 211.


Hardcastle, IR; Ahmed, SU; Atkins, H; Calvert, AH; Curtin, NJ; Farnie, G; Golding, BT; (2005) Isoindolinone-based inhibitors of the MDM2-p53 protein-protein interaction. BIOORG MED CHEM LETT , 15 (5) 1515 - 1520. 10.1016/j.bmcl.2004.12.061.

Hartmann, G; Vassileva, V; Piquette-Miller, M; (2005) Impact of endotoxin-induced changes in P-glycoprotein expression on disposition of doxorubicin in mice. DRUG METABOLISM AND DISPOSITION , 33 (6) pp. 820-828. 10.1124/dmd.104.002568.

Henderson, SR; Guiliano, D; Presneau, N; McLean, S; Frow, R; Vujovic, S; Anderson, J; (2005) A molecular map of mesenchymal tumors. GENOME BIOL , 6 (9) , Article R76. 10.1186/gb-2005-6-9-r76. Green open access

Ho, EA; Vassileva, V; Allen, C; Piquette-Miller, M; (2005) In vitro and in vivo characterization of a novel biocompatible polymer-lipid implant system for the sustained delivery of paclitaxel. JOURNAL OF CONTROLLED RELEASE , 104 (1) pp. 181-191. 10.1016/j.jconrel.2005.02.008.

Hoskin, PJ; Rojas, AM; Phillips, H; Saunders, MI; (2005) Acute and late morbidity in the treatment of advanced bladder carcinoma with accelerated radiotherapy, carbogen, and nicotinamide. Cancer , 103 (11) pp. 2287-2297. 10.1002/cncr.21048.

Howie, AJ; Pankhurst, T; Sarioglu, S; Turhan, N; Adu, D; (2005) Evolution of nephrotic-associated focal segmental glomerulosclerosis and relation to the glomerular tip lesion. KIDNEY INTERNATIONAL , 67 (3) pp. 987-1001. 10.1111/j.1523-1755.2005.00162.x.


Jonathan, C-B; (2005) Freezing used to kill cancer cells. The Sunday Times


Kalra, D; Singleton, P; Milan, J; MacKay, J; Detmer, D; Rector, A; Ingram, D; (2005) Security and confidentiality approach for the clinical E-Science framework (CLEF). METHODS OF INFORMATION IN MEDICINE , 44 (2) 193 - 197.

Kelly, CMA; Lee, SM; Steele, JP; (2005) Neoadjuvant chemotherapy for non-small cell lung cancer. In: Andrew, M, (ed.) Key Advances in Lung Cancer. (pp. 67-74). Aesculapius Medical Press: London, San Franscisco and Sydney.

Kim, J.B.; (2005) Development of a fully "humanized" xenograft model of breast cancer. Doctoral thesis, University of London. Green open access

Kim, JB; Price, RK; Stein, RC; O'Hare, MJ; (2005) Risks of the complementary medicine Rhodiola rosea in breast cancer. In: (pp. 3048S-3049S).

Kim, JB; Price, RK; Stein, RC; O'Hare, MJ; (2005) The risks of complementary medicine use (Rhodiola rosea) in breast cancer. In: (pp. 2698S-2698S).

Kim, JB; Stein, R; O'Hare, MJ; (2005) Tumour-stromal interactions in breast cancer: the role of stroma in tumourigenesis. Tumour Biol , 26 (4) pp. 173-185. 10.1159/000086950.

Kim, JB; Stein, RC; O'Hare, MJ; (2005) Development of a fully "humanized" xenograft model of breast cancer - New ideas for the development of pre-clinical prevention models. International Journal of Cancer Prevention , 2 (2) pp. 87-107.

Kogelberg, H; Tolner, B; Lowdell, M; Qureshi, U; Robson, M; Dearling, JL; Pedley, RB; (2005) Mechansims of clearance of the antibody-directed enzyme prodrug therapeutic, the mannosylated MFE-CP. In: (Proceedings) NCRI Cancer Conference Proceedings.

Kotecha, M; O'Hare, C; Wells, G; Howard, P; Thurston, D; Mantovani, R; Hartley, JA; (2005) Inhibition of DNA binding of the transcription factor complex NF-Y by a pyrrolobenzodiazepine-polyamide conjugate. In: CLINICAL CANCER RESEARCH. (pp. 9016S - 9016S). AMER ASSOC CANCER RESEARCH

Krause, M; Wohlfarth, J; Georgi, B; Pimentel, N; Dorner, D; Zips, D; Eicheler, W; (2005) Low-dose hyperradiosensitivity of human glioblastoma cell lines in vitro does not translate into improved outcome of ultrafractionated radiotherapy in vivo. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY , 81 (10) pp. 751-758.

Kristeleit, R; Fong, P; Aherne, GW; de Bono, J; (2005) Histone deacetylase inhibitors: emerging anticancer therapeutic agents? Clin Lung Cancer , 7 Supp S19-S30.


Lankester, K.J.; (2005) Magnetic resonance imaging and the development of vascular targeted treatments for cancer. Doctoral thesis, University of London. Green open access

LePla, RC; Landreau, CAS; Shipman, M; Hartley, JA; Jones, GDD; (2005) Azinomycin inspired bisepoxides: influence of linker structure on in vitro cytotoxicity and DNA interstrand cross-linking. BIOORG MED CHEM LETT , 15 (11) 2861 - 2864. 10.1016/j.bcml.2005.03.091.

Lee, M; Mahroof, S; Pringle, J; Short, SC; Briggs, TWR; Cannon, SR; (2005) Diffuse pigmented villonodular synovitis of the foot and ankle treated with surgery and radiotherapy. INTERNATIONAL ORTHOPAEDICS , 29 (6) pp. 403-405. 10.1007/s00264-005-0004-8.

Lo, S; Tolner, B; Taanman, JW; Cooper, JM; Gu, M; Hartley, JA; Schapira, AHV; (2005) Assessment of the significance of mitochondrial DNA damage by chemotherapeutic agents. INT J ONCOL , 27 (2) 337 - 344.


Marie-Egyptienne, DT; Cerone, MA; Londoño-Vallejo, JA; Autexier, C; (2005) A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation. Nucleic Acids Res , 33 (17) pp. 5446-5457. 10.1093/nar/gki848.

Martin, C; Ellis, T; McGurk, CJ; Jenkins, TC; Hartley, JA; Waring, MJ; Thurston, DE; (2005) Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: Footprinting and enzyme inhibition studies. BIOCHEMISTRY-US , 44 (11) 4135 - 4147. 10.1021/bi0479813.

McLean, SR; Gana-Weisz, M; Hartzoulakis, B; Frow, R; Whelan, J; Selwood, D; Boshoff, C; (2005) Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val(654)Ala. MOL CANCER THER , 4 (12) 2008 - 2015. 10.1158/1535-7163.MCT-05-0070.

Mulholland, PJ; Thirlwell, C; Brock, CS; Newlands, ES; (2005) Emerging targeted treatments for malignant glioma. Expert Opin Emerg Drugs , 10 (4) pp. 845-854. 10.1517/14728214.10.4.845.


Nooij, MA; Whelan, J; Bramwell, VHC; Taminiau, AT; Cannon, S; Hogendoorn, PCW; Pringle, J; (2005) Doxorubicin and cisplatin chemotherapy in high-grade spindle cell sarcomas of the bone, other than osteosarcoma or malignant fibrous histiocytoma: a European Osteosarcoma Intergroup Study. EUR J CANCER , 41 (2) 225 - 230. 10.1016/j.ejca.2004.08.026.


O'Connell, NM; Saunders, RE; Lee, CA; Perry, DJ; Perkins, SJ; (2005) Structural interpretation of 42 mutations causing factor XI deficiency using homology modeling. J THROMB HAEMOST , 3 (1) 127 - 138.


Padhani, AR; Ah-See, ML; Makris, A; (2005) MRI in the detection and management of breast cancer. Expert review of anticancer therapy , 5 (2) pp. 239-252.

Parker, LL; Anderson, FM; O'Hare, CC; Lacy, SM; Bingham, JP; Robins, DJ; Hartley, JA; (2005) Synthesis of novel DNA cross-linking antitumour agents based on polyazamacrocycles. BIOORGAN MED CHEM , 13 (7) 2389 - 2395. 10.1016/j.bmc.2005.01.055.

Peltenburg, LT; de Bruin, EC; Meersma, D; Smit, NP; Schrier, PI; Medema, JP; (2005) Expression and function of the apoptosis effector Apaf-1 in melanoma. Cell Death Differ , 12 (6) pp. 678-679. 10.1038/sj.cdd.4401630.

Peter, M; Ameer-Beg, SM; Hughes, MKY; Keppler, MD; Prag, S; Marsh, M; Vojnovic, B; (2005) Multiphoton-FLIM quantification of the EGFP-mRFP1 FRET pair for localization of membrane receptor-kinase interactions. BIOPHYSICAL JOURNAL , 88 (2) pp. 1224-1237. 10.1529/biophysj.104.050153.

Pinto, ES; Mensah, R; Meeran, K; Cameron, JD; Murugaesu, N; Bulpitt, CJ; Rajkumar, C; (2005) Peripheral arterial compliance differs between races: comparison among Asian, Afro-Caribbeans, and white Caucasians with type 2 diabetes. Diabetes Care , 28 (2) 496-.

Plummer, ER; Middleton, MR; Jones, C; Olsen, A; Hickson, I; McHugh, P; Margison, GP; (2005) Temozolomide pharmacodynamics in patients with metastatic melanoma: DNA damage and activity of repair enzymes 6-alkylguanine alkyltransferase and poly(ADP-ribose) polymerase-1. CLIN CANCER RES , 11 (9) 3402 - 3409.

Price, CA; Lingerfelt, BM; Handl, HL; Kiakos, K; Hartley, JA; Lee, M; (2005) Sequence specific recognition of DNA by tailor-made hairpin conjugates of achiral seco-cyclopropaneindoline-2-benzofurancarboxamide and pyrrole-imidazole polyamides. Bioorg Med Chem Lett , 15 (12) pp. 3151-3156. 10.1016/j.bmcl.2005.04.006.

Pritchard-Jones, K; Spendlove, I; Wilton, C; Whelan, J; Weeden, S; Lewis, I; Hale, J; (2005) Immune responses to the 105AD7 human anti-idiotypic vaccine after intensive chemotherapy, for osteosarcoma. British Journal of Cancer , 92 (8) pp. 1358-1365. 10.1038/sj.bjc.6602500.


Rada-Iglesias, A; Wallerman, O; Koch, C; Ameur, A; Enroth, S; Clelland, G; Wester, K; (2005) Binding sites for metabolic disease related transcription factors inferred at base pair resolution by chromatin immunoprecipitation and genomic microarrays. HUM MOL GENET , 14 (22) 3435 - 3447. 10.1093/hmg/ddi378.

Ravn, P; Thornton, A; Chester, KA; Pedley, B; Davidson, B; Winslet, M; Ogunbiyi, O; (2005) In situ selection of single chain antibodies by ex vivo perfusion of tumour-bearing human organs with phage display antibody libraries. In: (Proceedings) NCRI Cancer Conference Proceedings.

Ross, MT; Grafham, DV; Coffey, AJ; Scherer, S; McLay, K; Muzny, D; Platzer, M; (2005) The DNA sequence of the human X chromosome. NATURE , 434 (7031) 325 - 337. 10.1038/nature03440.

Rudd, RM; Gower, NH; Spiro, SG; Eisen, TG; Harper, PG; Littler, JAH; Hatton, M; (2005) Gemcitabine plus carboplatin versus mitomycin, ifosfamide, and cisplatin in patients with stage IIIB or IV non-small-cell lung cancer: A phase III randomized study of the London Lung Cancer Group. JOURNAL OF CLINICAL ONCOLOGY , 23 (1) pp. 142-153. 10.1200/JCO.2005.03.037.

Rudd, RM; Gower, NH; Spiro, SG; Lee, SM; Eisen, TG; Harper, PG; Hatton, M; (2005) Is the tolerance to MIP chemotherapy different between English and other European populations? - Reply. JOURNAL OF CLINICAL ONCOLOGY , 23 (25) pp. 6270-6271. 10.1200/JCO.2005.01.7640.


Sato, A; McNulty, L; Cox, K; Kim, S; Scott, A; Daniell, K; Summerville, K; (2005) A novel class of in vivo active anticancer agents: achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065. J Med Chem , 48 (11) pp. 3903-3918. 10.1021/jm050179u.

Sato, A; McNulty, LA; Cox, K; Kim, S; Scott, A; Daniell, K; Summerville, K; (2005) A novel class of in vivo active anticancer agents: Achiral seco-amino- and seco-hydroxycyclopropylbenz[e]indolone (seco-CBI) analogues of the duocarmycins and CC-1065. J MED CHEM , 48 (11) 3903 - 3918. 10.1021/jm050179u.

Seddon, BM; Cassoni, AM; Galloway, MJ; Rees, JH; Whelan, JS; (2005) Fatal radiation myelopathy after high-dose busulfan and melphalan chemotherapy and radiotherapy for Ewing's sarcoma: A review of the literature and implications for practice. CLIN ONCOL-UK , 17 (5) 385 - 390. 10.1016/j.clon.2005.03.004.

Senis, YA; Atkinson, BT; Pearce, AC; Wonerow, P; Auger, JM; Okkenhaug, K; Pearce, W; (2005) Role of the p110 delta PI 3-kinase in integrin and ITAM receptor signalling in platelets. PLATELETS , 16 (3-4) pp. 191-202. 10.1080/09537100400016711.

Sharma, SK; Bagshawe, KD; Begent, RH; (2005) Advances in antibody-directed enzyme prodrug therapy. Curr Opin Investig Drugs , 6 (6) pp. 611-615.

Sharma, SK; Pedley, RB; Bhatia, J; Boxer, GM; El-Emir, E; Qureshi, U; Tolner, B; (2005) Sustained tumor regression of human colorectal cancer xenografts using a multifunctional mannosylated fusion protein in antibody-directed enzyme prodrug therapy. CLIN CANCER RES , 11 (2) 814 - 825.

Sharma, SK; Pedley, RB; Meyer, A; Tolner, B; Griffin, N; Green, A; Boxer, GM; (2005) Pharmacokinetics and pharmakodynamics of a glycosylated antibody-enzyme fusion protein for ADEPT. In: (Proceedings) Proceedings American Association for Cancer Research. (pp. 984-).

Short, S; Bourne, S; Martindale, C; Woodcock, M; Jackson, SP; (2005) DNA damage responses at low radiation doses. Radiation Research , 164 (3) pp. 292-302. 10.1667/RR3421.1.

Short, S; Buffa, F; Koritzinsky, M; Wouters, B; Bentzen, SM; (2005) Radiation induced changes in gene expression in human glioma cells. In:

Short, S; C, B; F, K; M, W; B, B; S, M; (2005) UNSPECIFIED In: (Proceedings) 6th Wolfsberg Conference on Molecular Radiation Biology/Oncology.

Sujobert, P; Bardet, V; Cornillet-Lefebvre, P; Hayflick, JS; Prie, N; Verdier, F; Vanhaesebroeck, B; (2005) Essential role for the p110 delta isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia. BLOOD , 106 (3) 1063 - 1066. 10.1128/blood-2004-08-3225.

Sujobert, P; Bardet, V; Cornillet-Lefebvre, P; Hayflick, JS; Prie, N; Verdier, F; Vanhaesebroeck, B; (2005) Essential role for the p110 delta isoform in phosphoinositide 3-kinase activation and cell proliferation in acute myeloid leukemia. BLOOD , 106 (3) pp. 1063-1066. 10.1128/blood-2004-08-3225.


Thomas, MJ; Smith, A; Head, DH; Milne, L; Nicholls, A; Pearce, W; Vanhaesebroeck, B; (2005) Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases. EUR J IMMUNOL , 35 (4) 1283 - 1291. 10.1002/eji.200425634.

Thomas, MJ; Smith, A; Head, DH; Milne, L; Nicholls, A; Pearce, W; Vanhaesebroeck, B; (2005) Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases. EUROPEAN JOURNAL OF IMMUNOLOGY , 35 (4) pp. 1283-1291. 10.1002/eji.200425634.

Tominaga, Y; Tamgüney, T; Kolesnichenko, M; Bilanges, B; Stokoe, D; (2005) Translational deregulation in PDK-1-/- embryonic stem cells. Mol Cell Biol , 25 (19) pp. 8465-8475. 10.1128/MCB.25.19.8465-8475.2005.

Toth, JL; Trzupek, JD; Flores, LV; Kiakos, K; Hartley, JA; Pennington, WT; Lee, M; (2005) A novel achiral seco-amino-cyclopropylindoline (CI) analog of CC-1065 and the duocarmycins: design, synthesis and biological studies. Med Chem , 1 (1) pp. 13-19.


Valle, JW; Dangoor, A; Beech, J; Lee, SM; Scarffe, JH; Swindell, R; Ranson, M; (2005) Treatment of inoperable hepatocellular carcinoma (HCC) with pegylated liposomal doxorubicin (PLD) – results of a phase II study. British Journal of Cancer , 92 (4) pp. 628-630.

Vanhaesebroeck, B; Ali, K; Bilancio, A; Geering, B; Foukas, LC; (2005) Signalling by PI3K isoforms: insights from gene-targeted mice. TRENDS IN BIOCHEMICAL SCIENCES , 30 (4) pp. 194-204. 10.1016/j.tibs.2005.02.008.

UNSPECIFIED (Ed). (2005) Novel implantable delivery system increases maximum tolerable doses of paclitaxel in mice. [Whole issue]. Proc Amer Assoc Cancer Res , 46


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This list was generated on Sun Mar 26 03:57:18 2017 BST.