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Number of items: 113.

A

Adams, M; Calvert, AH; Carmichael, J; Clark, PI; Coleman, RE; Earl, HM; Gallagher, CJ; (1998) Chemotherapy for ovarian cancer - a consensus statement on standard practice. BRIT J CANCER , 78 (11) 1404 - 1406.

Almassy, R; Bowman, K; Calvert, AH; Curtin, NJ; Golding, BT; Hostomska, Z; Hostomsky, Z; (1998) 2-phenylbenzimidazole-4-carboxamides are potent inhibitors of the DNA repair enzyme poly(ADP-ribose)-polymerase (PARP). ANN ONCOL , 9 30 - 31.

Almassy, R; Bowman, K; Calvert, AH; Curtin, NJ; Golding, BT; Hostomska, Z; Hostomsky, Z; (1998) 2-phenylbenzimidazole-4-carboxamides are potent inhibitors of the DNA repair enzyme poly(ADP-ribose)-polymerase (PARP). Annals of Oncology , 9 116-.

Arcaro, A; Volinia, S; Zvelebil, MJ; Stein, R; Watton, SJ; Layton, MJ; Gout, I; (1998) Human phosphoinositide 3-kinase C2 beta, the role of calcium and the C2 domain in enzyme activity. JOURNAL OF BIOLOGICAL CHEMISTRY , 273 (49) pp. 33082-33090. 10.1074/jbc.273.49.33082.

B

Begent, RHJ; Napier, MP; Sharma, SK; Springer, CJ; Bagshawe, KD; Green, AJ; Martin, J; (1998) Antibody-directed enzyme prodrug therapy (ADEPT). ANN ONCOL , 9 23 - 23.

Bhatia, J; Pedley, RB; Sharma, SK; Boxer, GM; Read, DA; Boden, RW; Michael, P; (1998) A distribution study at sub-millimetre resolution of a recombinant MFE-23 : CPG(2) fusion protein in a colorectal cancer xenograft model. BRIT J CANCER , 78 61 - 61.

Bhatia, J; Pedley, RB; Sharma, SK; Boxer, GM; Read, DA; Boden, RW; Michael, P; (1998) A distribution study at sub-millimetre resolution of a recombinant MFE-23:CPG(2) fusion protein in a colorectal cancer xenograft model. British Journal of Cancer , 78 p. 147.

Bhatia, J; Pedley, RB; Sharma, SK; Boxer, GM; Read, DA; Michael, P; Boden, RW; (1998) A distribution study at sub-millimetre resolution of a recombinant MFE:CPG2 fusion protein in a colorectal cancer xenograft model. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 61-).

Botelli, R; Tibballs, J; Hochhauser, D; Watkinson, A; Dick, R; Burroughs, AK; (1998) Ultrasound screening for hepatocellular carcinoma (HCC) in cirrhosis: the evidence for an established clinical practice. CLIN RADIOL , 53 (10) 713 - 716.

Boxer, GM; Mayer, A; O'Malley, D; Tsiompanou, E; Winslet, MC; Lewis, AAM; Dhillon, AP; (1998) Radioimmunoguided surgery (RIGS) of colorectal cancer with single chain Fv antibody to CEA. BRIT J CANCER , 78 10 - 10.

C

Calvert, AH; Walling, JM; (1998) Clinical studies with MTA. BRIT J CANCER , 78 35 - 40.

Caroline, R; (1998) My cancer and the magic bullet. UNSPECIFIED

Cassoni, AM; Whelan, JS; (1998) Ewing's sarcoma: hyperfractionated radiotherapy with concurrent chemotherapy: acute toxicity. A prospective single institutional study. In:

Cooke, SP; Lawrence, L; Boxer, GM; Chester, KA; Begent, RHJ; (1998) Phage-derived single chain Fv antibody fragments to vascular endothelial cell growth factor. In: (pp. p. 91).

Cooke, SP; Lawrence, L; Boxer, GM; Chester, KA; Begent, RHJ; (1998) Phage-derived single chain Fv antibody fragments to vascular endothelial cell growth factor. BRIT J CANCER , 78 47 - 47.

Cummings, J; Spanswick, VJ; Gardiner, J; Ritchie, A; Smyth, JF; (1998) Pharmacological and biochemical determinants of the antitumour activity of the indoloquinone EO9. BIOCHEM PHARMACOL , 55 (3) 253 - 260.

Cummings, J; Spanswick, VJ; Ritchie, AA; Smyth, JF; (1998) Pharmacological determinants of the antitumour activity of mitomycin C - implications for enzyme directed drug development. ANN ONCOL , 9 134 - 134.

Cummings, J; Spanswick, VJ; Tomasz, M; Smyth, JF; (1998) Enzymology of mitomycin C metabolic activation in tumour tissue - Implications for enzyme-directed bioreductive drug development. BIOCHEM PHARMACOL , 56 (4) 405 - 414.

D

Decoster, E; Cornelis, S; Vanhaesebroeck, B; Fiers, W; (1998) Autocrine tumor necrosis factor (TNF) and lymphotoxin (LT) alpha differentially modulate cellular sensitivity to TNF/LT-alpha cytotoxicity in L929 cells. J Cell Biol , 143 (7) pp. 2057-2065.

Decoster, E; Vanhaesebroeck, B; Boone, E; Plaisance, S; De Vos, K; Haegeman, G; Grooten, J; (1998) Induction of unresponsiveness to tumor necrosis factor (TNF) after autocrine TNF expression requires TNF membrane retention. J Biol Chem , 273 (6) pp. 3271-3277.

Deora, AA; Win, T; Vanhaesebroeck, B; Lander, HM; (1998) A redox-triggered ras-effector interaction. Recruitment of phosphatidylinositol 3'-kinase to Ras by redox stress. J Biol Chem , 273 (45) pp. 29923-29928.

Dische, S; Saunders, MI; (1998) Hypoxic cell radiosensitiation- clinical relevance in1998. In: Kogelnik, HD and Sedlmayer, E, (eds.) Progress in Radio-oncology VI. (pp. 205-223). Monduzzi

deKretser, D; Skakkebaek, NE; Wylie, CC; Harland, SJ; Oosterhuis, JW; (1998) Germ cell cancer and disorders of spermatogenesis: An environmental connection? Discussion. Apmis , 106 p. 12.

E

Endicott, J; Noble, M; Lawrie, A; Tunnah, P; Brown, N; Johnson, L; Calvert, A; (1998) Insights into CDK inhibitor design from X-ray crystallographic studies. ANN ONCOL , 9 3 - 3.

F

Flynn, AA; Green, AJ; Boxer, GM; Pedley, RB; Begent, RHJ; (1998) A dosimetry model for the accurate characterisation of absorbed doses in mouse organs. In: BRIT J CANCER. (pp. 39 - 39). CHURCHILL LIVINGSTONE

G

Geh, JI; Makris, A; Ashford, R; Grosch, E; GlynneJones, R; (1998) Preoperative chemoradiotherapy for locally advanced rectal cancer. British Journal of Cancer , 78 p. 23.

Gerrard, G; Short, S; C, ; (1998) The future of oncology training from the trainees' perspective. Clinical Oncology , 10 pp. 84-91.

Gibson, V; Anderson, RJ; Hartley, JA; Cairns, D; (1998) Synthesis of anthraquinone-oligodeoxynucleotide conjugates as inhibitors of gene transcription. Annals of Oncology , 9 p. 101.

Gibson, V; Anderson, RJ; Hartley, JA; Cairns, D; (1998) Synthesis of anthraquinone-oligodeoxynucleotide conjugates as inhibitors of gene transcription. ANN ONCOL , 9 27 - 27.

Goodchild, KA; Hill, SA; Chaplin, DJ; Hoskin, PJ; Saunders, MI; (1998) Modification of human tumour blood flow using pentoxifylline and carbogen. British Journal of Cancer , 78 p. 45.

Grant, S; Boyle, F; Calvert, AH; Curtin, NJ; Endicott, J; Golding, BT; Griffin, RJ; (1998) O-6-alkylguanines as selective inhibitors of cyclin dependent kinases. Annals of Oncology , 9 523-.

Griffin, RJ; Srinivasan, S; Bowman, K; Calvert, AH; Curtin, NJ; Newell, DR; Pemberton, LC; (1998) Resistance-modifying agents. 5. Synthesis and biological properties of quinazolinone inhibitors of the DNA repair enzyme poly(ADP-ribose) polymerase (PARP). J MED CHEM , 41 (26) 5247 - 5256.

H

Harland, SJ; Cook, PA; Fossa, SD; Horwich, A; Mead, GM; Parkinson, MC; Roberts, JT; (1998) Intratubular germ cell neoplasia of the contralateral testis in testicular cancer: Defining a high risk group. J UROLOGY , 160 (4) 1353 - 1357.

Harland, SJ; Linke, J; Kliesch, S; Looijenga, L; Dieckmann, KP; Grigor, K; Skakkebaek, NE; (1998) The value of the biopsy of the contralateral testis in patients with testicular germ cell cancer: The recent German experience -Discussion. Apmis , 106 pp. 20-23.

Harland, SJ; Nicholson, PW; (1998) Implications of a hereditary model for testis cancer. In: Jones, WG and Appleyard, I and Harnden, P and Joffe, JK, (eds.) Germ Cell Tumours IV. (pp. 17-25). John Libbey & Co. Ltd.

Hartley, JM; Spanswick, VJ; Gander, M; Giacomini, G; Whelan, J; Souhami, RL; Hartley, JA; (1998) Detection of DNA interstrand crosslinking in clinical samples using the single cell COMET assay. Annals of Oncology , 9 p. 645.

Hartley, JM; Spanswick, VJ; Gander, M; Giacomini, G; Whelan, J; Souhami, RL; Hartley, JA; (1998) Detection of DNA interstrand crosslinking in clinical samples using the single cell COMET assay. ANN ONCOL , 9 169 - 169.

Hartley, JM; Spanswick, VJ; Gander, M; Giacomini, G; Whelan, JS; Souhami, RL; Hartley, JA; (1998) Detection of DNA interstrand crosslinking in clinical samples using the single cell COMET assay. In:

Henderson, ND; Lacy, SM; O'Hare, CC; Hartley, JA; McClean, S; Wakelin, LPG; Kelland, LR; (1998) Synthesis of new bifunctional compounds which selectively alkylate guanines in DNA. ANTI-CANCER DRUG DES , 13 (7) 749 - 768.

Hochhauser, D; (1998) Arsenic compound effective in leukaemia. LANCET , 351 (9108) 1037 - 1037.

Hochhauser, D; (1998) Molecular biologists map pathways to gastrointestinal cancer. LANCET , 351 (9109) 1109 - 1109.

Holford, J; Raynaud, F; Murrer, BA; Grimaldi, K; Hartley, JA; Abrams, M; Kelland, LR; (1998) Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis-[amminedichloro(2-methylpyridine)] platinum(II) (AMD473). ANTI-CANCER DRUG DES , 13 (1) 1 - 18.

Hoskin, PJ; (1998) Major advances in the management of metastatic bone pain. UNSPECIFIED

Hoskin, PJ; (1998) Palliativtherapie. In: Schmitt, G and Pape, H and Doker, RD, (eds.) Diagnostik und Interdisziplinare Therapie maligner Tumoren-Eine Einfuhrung fur Studierende und Arzte-Herausgeber. Unimed Verlag, Lorch/Bremen

Hoskin, PJ; Makin, W; (1998) Oncology for Palliative Medicine. [Book]. Oxford University Press

Hoskin, PJ; Rembowska, A; (1998) Dosimetry rules for brachytherapy using high dose rate remote afterloading implants. CLIN ONCOL , 10 pp. 226-230.

Hoskin, PJ; Saunders, MI; Goodchild, K; Powell, MEB; Taylor, J; Baddeley, H; (1998) Dynamic contrast enhanced magnetic resonance scanning to predict outcome after radiotherapy for head & neck cancer. British Journal of Cancer , 78 p. 15.

Hughes, AN; Griffin, MJ; Calvert, AH; Johnston, A; Kerr, B; Lee, C; Newell, DR; (1998) Pharmacokinetic interactions in a phase I study of nolatrexed (AG337, THYMITAQ (TM)) and paclitaxel in patients with advanced solid tumours. Annals of Oncology , 9 463-.

J

Jackman, AL; Mitchell, F; Lynn, S; Aherne, GW; Rees, C; Calvert, AH; Judson, IR; (1998) Evidence for the duration of the antifolate action of the thymidylate synthase (TS) inhibitor ZD9331 using plasma dUrd as a surrogate marker of enzyme inhibition. Annals of Oncology , 9 604O-.

Jayson, GC; Middleton, M; Lee, SM; Ashcroft, L; Thatcher, N; (1998) A randomized phase II trial of interleukin 2 and interleukin 2-interferon alpha in advanced renal cancer. British Journal of Cancer , 78 (3) pp. 366-369.

Ju, JF; Banerjee, D; Lenz, HJ; Danenberg, KD; Schmittgen, TC; Spears, CP; Schonthal, AH; (1998) Restoration of wild-type p53 activity in p53-null HL-60 cells confers multidrug sensitivity. CLIN CANCER RES , 4 (5) 1315 - 1322.

Judson, I; Maughan, T; Beale, P; Primrose, J; Hoskin, P; Hanwell, J; Berry, C; (1998) Effects of impaired renal function on the pharmacokinetics of raltitrexed (Tomudex ZD1694). British Journal of Cancer , 78 pp. 1188-1193.

K

Kakouri, E; Whelan, JS; Coltart, S; Smith, MEF; Souhami, RL; (1998) Multifocal, multicentric Angiosarcoma of bone. Sarcoma , 1 pp. 183-188. Gold open access

Koberle, B; Masters, JRW; Hartley, JA; Wood, RD; (1998) Reduced Capacity for initial stages of nuceotide excision repair in two testis tumour cell lines. PROC AM ASSOC CANCER RES , 39 p. 535.

Konishi, H; Ochiya, T; Chester, KA; Begent, RHJ; Muto, T; Sugimura, T; Terada, M; (1998) Targeting strategy for gene delivery to carcinoembryonic antigen-producing cancer cells by retrovirus displaying a single-chain variable fragment antibody. Human Gene Therapy , 9 pp. 235-248.

Kretser, D; Giwercman, A; Heidenreich, A; Oliver, RTD; Kliesch, S; Harland, SJ; Lauke, H; (1998) Gonadal function in men with testicular cancer: Biological and clinical aspects - Discussion. Apmis , 106 pp. 34-36.

Kupchinsky, S; Espinosa, JE; Johnson, K; Steadman, B; Brooks, N; Hartley, JA; Lee, M; (1998) Design, synthesis and DNA binding properties of a series of 4,5-bis(substituted)-1,2,3-triazole derivatives of imidazole- and pyrrole-containing analogs of distamycin. HETEROCYCL COMMUN , 4 (5) 415 - 422.

L

Lee, SM; Radford, JA; Dobson, L; Huq, T; Ryder, WDJ; Pettengell, R; Morgenstern, GR; (1998) Recombinant human granulocyte colony-stimulating factor (filgrastim) following high-dose chemotherapy and peripheral blood progenitor cell rescue in high-grade non-Hodgkin's lymphoma: clinical benefits at no extra cost. British Journal of Cancer , 77 (8) pp. 1294-1299.

M

Maini, MK; Wedderburn, LR; Hall, FC; Wack, A; Casorati, G; Beverley, PCL; (1998) Comparison of two techniques for the molecular tracking of specific T-cell responses; CD4(+) human T-cell clones persist in a stable hierarchy but at a lower frequency than clones in the CD8(+) population. IMMUNOLOGY , 94 (4) 529 - 535.

Makris, A; Powles, TJ; Allred, DC; Ashley, S; Ormerod, MG; Titley, JC; Dowsett, M; (1998) Changes in hormone receptors and proliferation markers in tamoxifen treated breast cancer patients and the relationship with response. Breast Cancer Research And Treatment , 48 pp. 11-20.

Makris, A; Powles, TJ; Ashley, SE; Chang, J; Hickish, T; Tidy, VA; Nash, AG; (1998) A reduction in the requirements for mastectomy in a randomized trial of neoadjuvant chemoendocrine therapy in primary breast cancer. Annals of Oncology , 9 pp. 1179-1184.

Makris, A; Powles, TJ; Titley, J; Trott, PA; Ormerod, MG; (1998) Evidence for metastases to a single axillary lymph node from two separate primary breast carcinomas. Breast , 7 pp. 173-176.

Marshman, E; Calvert, AH; Newell, DR; Curtin, NJ; (1998) Dipyridamole selectively potentiates antipurine antifolates in human tumour cell lines but not normal tissue targets of dose-limiting toxicity. Annals of Oncology , 9 589-.

Marshman, E; Newell, DR; Calvert, AH; Dickinson, AM; Patel, HRH; Campbell, FC; Curtin, NJ; (1998) Dipyridamole potentiates antipurine antifolate activity in the presence of hypoxanthine in tumor cells but not in normal tissues in vitro. CLIN CANCER RES , 4 (11) 2895 - 2902.

Mayer, A; Boxer, GM; O'Malley, D; Tsiompanou, E; Flynn, AA; Davidson, BR; Winslet, MC; (1998) An anti-CEA single chain Fv antibody for radioimmunoguided surgery in colorectal cancer. ANN ONCOL , 9 35 - 35.

Mayer, A; Chester, KA; Bhatia, J; Pedley, RB; Read, DA; Boxer, GM; Begent, RHJ; (1998) Exemplifying guidelines for preparation of recombinant DNA products in phase I trials in cancer: Preparation of a genetically engineered anti-CEa single chain Fv antibody. EUR J CANCER , 34 (7) 968 - 976.

McAdam, SR; Knox, RJ; Hartley, JA; Masters, JRW; (1998) KW-2149 (7-N-[2-[gamma-L-glutamylamino]ethyldithio-ethyl] mitomycin C): DNA interactions and drug uptake following serum activation. BIOCHEM PHARMACOL , 55 (11) 1777 - 1783.

McDonald, AC; Vasey, PA; Adams, L; Walling, J; Woodworth, JR; Abrahams, T; McCarthy, S; (1998) A Phase I and pharmacokinetic study of LY231514, the multitargeted antifolate. CLIN CANCER RES , 4 (3) 605 - 610.

Mead, GM; Russell, M; Clark, P; Harland, SJ; Harper, PG; Cowan, R; Roberts, JT; (1998) A randomized trial comparing methotrexate and vinblastine (MV) with cisplatin, methotrexate and vinblastine (CMV) in advanced transitional cell carcinoma: results and a report on prognostic factors in a Medical Research Council study. MRC Advanced Bladder Cancer Working Party. Br J Cancer , 78 (8) pp. 1067-1075.

Meyer, T; Hart, IR; (1998) Mechanisms of tumour metastasis. Eur J Cancer , 34 (2) pp. 214-221.

Meyer, T; Marshall, JF; Hart, IR; (1998) Expression of alphav integrins and vitronectin receptor identity in breast cancer cells. Br J Cancer , 77 (4) pp. 530-536.

Middleton, MR; Lorigan, P; Lee, SM; Yip, D; Davies, J; Harper, P; Thatcher, N; (1998) Dacarbazine, BCNU, cisplatin and tamoxifen (DBCT) v dacarbazine and interferon (DTIC/Ifn) in advanced melanoma: results of a randomised phase lll study. In: (Proceedings) 1998 ASCO Annual Meeting/34th Annual Meeting, Los Angeles, CA.. (pp. 508a-). Proceedings of the American Society of Clinical Oncology

Middleton, MR; Lunn, JM; Morris, C; Rustin, G; Wedge, SR; Brampton, MH; Lind, MJ; (1998) O-6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. British Journal of Cancer , 78 (9) pp. 1199-1202.

Middleton, MR; Lunn, JM; Morris, C; Rustin, G; Wedge, SR; Brampton, MH; Lind, MJ; (1998) O-6-methylguanine-DNA methyltransferase in pretreatment tumour biopsies as a predictor of response to temozolomide in melanoma. BRIT J CANCER , 78 (9) 1199 - 1202.

Mitchell, F; Lynn, S; Rees, C; Judson, I; Calvert, AH; Ratain, M; Diab, S; (1998) Plasma 2 '-deoxyuridine (dUrd) as a surrogate marker of thymidylate synthase (TS) inhibition in patients in phase I clinical trials of the TS inhibitor ZD9331. Annals of Oncology , 9 614-.

P

Page, D; Ekbom, A; Skakkebaek, NE; Rorth, M; Harland, SJ; Hardell, L; Auger, J; (1998) Increasing incidence of testicular cancer - birth cohort effects - Discussion. Apmis , 106 pp. 229-231.

Patrick, MR; Chester, KA; Pietersz, GA; (1998) In vitro characterization of a recombinant P-32-phosphorylated anti- (carcinoembryonic antigen) single-chain antibody. Cancer Immunology, Immunotherapy , 46 pp. 229-237.

Pedley, RB; Sharma, SK; Boden, R; Boxer, GM; Springer, CJ; Begent, RHJ; (1998) Enhancement of adept with anti-vasculature drugs in a xenograft model. BRIT J CANCER , 78 51 - 51.

Pietersz, GA; Patrick, MR; Chester, KA; (1998) Preclinical characterization and in vivo imaging studies of an engineered recombinant technetium-99m-labeled metallothionein-containing anti-carcinoembryonic antigen single-chain antibody. Journal of Nuclear Medicine , 39 pp. 47-56.

Plummer, R; Calvert, AH; Judson, I; Beale, P; Rees, C; Gokal, S; Highley, M; (1998) Phase I trial of ZD9331 given as a 30 minute infusion on days 1 and 8 with cycles repeated every 3 weeks. Annals of Oncology , 9 617-.

Price, P; Hoskin, PJ; Hutchinson, T; Stenning, S; UK Med Res Council, ; (1998) What is the role of radiation-chemotherapy in the radical non-surgical management of carcinoma of the oesophagus? BRIT J CANCER , 78 (4) 504 - 507.

Prvulovich, EM; Stein, RC; Bomanji, JB; Ledermann, JA; Taylor, I; Ell, PJ; (1998) Iodine-131-MIBG therapy of a patient with carcinoid liver metastases. J NUCL MED , 39 (10) 1743 - 1745.

R

Rafi, I; Boddy, AV; Calvete, JA; Taylor, GA; Newell, DR; Bailey, NP; Lind, MJ; (1998) Preclinical and phase I clinical studies with the nonclassical antifolate thymidylate synthase inhibitor nolatrexed dihydrochloride given by prolonged administration in patients with solid tumors. J CLIN ONCOL , 16 (3) 1131 - 1141.

Raven, C; Vanhaesebroeck, B; Waterfield, M; Ward, SG; (1998) The p110 δ isoform of phosphatidylinositol 3-kinase associates with the T lymphocyte costimulatory molecule CD28. FASEB Journal , 12 (5)

Rees, C; Beale, P; Plummer, R; Highley, M; Calvert, AH; Judson, I; Smith, R; (1998) Phase I trial of ZD9331 given as a 30 minute infusion on days 1 and 8 with cycles repeated every 3 weeks. Annals of Oncology , 9 628P-.

Roy, K; Chiao, JH; Spengler, BA; Tolner, B; Yang, CH; Biedler, JL; Sirotnak, FM; (1998) Chromosomal localization of the murine RFC-1 gene encoding a folate transporter and its amplification in an antifolate resistant variant overproducing the transporter. CANCER GENET CYTOGEN , 105 (1) 29 - 38.

Roy, K; Tolner, B; Chiao, JH; Sirotnak, FM; (1998) A single amino acid difference within the folate transporter encoded by the murine RFC-1 gene selectively alters its interaction with folate analogues - Implications for intrinsic antifolate resistance and directional orientation of the transporter within the plasma membrane of tumor cells. J BIOL CHEM , 273 (5) 2526 - 2531. Gold open access

S

Saunders, MI; (1998) CHART: The results and the relevance to clinical practice. In: Kogelnik, HD and Sedlmayer, E, (eds.) Progress in Radio-Oncology VI. (pp. 753-767). Monduzzi

Saunders, MI; Rojas, A; Lyn, BE; Pigott, K; Powell, M; Goodchild, K; Hoskin, PJ; (1998) Experience with dose escalation using CHARTWEL (continuous hyperfractionated accelerated radiotherapy weekend less) in non-small-cell lung cancer. Br J Cancer , 78 (10) pp. 1323-1328.

Shah, N; Hoskin, P; Saunders, M; Novell, R; Makris, A; (1998) Low dose Folinic acid with bolus and infusional 5 Fluorouracil chemotherapy in advanced colorectal carcinomas. British Journal of Cancer , 78 p. 62.

Sharma, SK; Bhatia, J; Pedley, RB; Read, DA; Michael, P; Boden, RW; Chester, KA; (1998) Biodistribution of enzyme activity of a fusion protein for use in ADEPT. In: (pp. p. 48).

Sharma, SK; Bhatia, J; Pedley, RB; Read, DA; Michael, P; Boden, RW; Chester, KA; (1998) Biodistribution of enzyme activity of a fusion protein for use in ADEPT. BRIT J CANCER , 78 14 - 14.

Sharma, SK; Bhatia, J; Pedley, RB; Read, DA; Michael, P; Chester, KAAB; R, HJ; (1998) In vivo enzyme activity of a fusion protein for use in ADEPT. In: (Proceedings) Proceedings Americal Association for Cancer Research. (pp. 277-).

Short, S; (1998) UNSPECIFIED In: (Proceedings) Low dose effects.

Short, S; (1998) UNSPECIFIED In: (Proceedings) The British Institute of Radiology 'New ideas in fractionation'.

Short, S; C, J; M, ; (1998) Cellular response to low-dose irradiation. Clinical Oncology , 10 pp. 73-78.

Siegal, G; Davis, B; Kristensen, SM; Sankar, A; Linacre, J; Stein, RC; Panayotou, G; (1998) Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. JOURNAL OF MOLECULAR BIOLOGY , 276 (2) pp. 461-478. 10.1006/jmbi.1997.1562.

Siegal, G; Davis, B; Kristensen, SM; Sankar, A; Linacre, J; Stein, RC; Panayotou, G; (1998) Solution structure of the C-terminal SH2 domain of the p85 alpha regulatory subunit of phosphoinositide 3-kinase. Journal of Molecular Biology , 276 pp. 461-478.

Singer, JM; Hartley, JM; Brennan, C; Nicholson, PW; Souhami, RL; (1998) The pharmacokinetics and metabolism of ifosfamide during bolus and infusional administration: a randomized cross-over study. British Journal of Cancer , 77 pp. 978-984.

Smith, PG; Newell, DR; Barnes, MJ; Calvert, AH; Curtin, NJ; (1998) Potentiation of the in vitro activity of the multi-targeted antifolate MTA (LY231514) by dipyridamole. Annals of Oncology , 9 588-.

Smyth, J; Schellens, J; Kerger, J; Calvert, H; Bruntsch, U; Hanauske, A; EORTC Early Clinical Studies Grp, ; (1998) LU 103793 has activity in melanoma patients. ANN ONCOL , 9 116 - 116.

Spanswick, VJ; Cummings, J; Ritchie, AA; Smyth, JF; (1998) Pharmacological determinants of the antitumour activity of mitomycin C. BIOCHEM PHARMACOL , 56 (11) 1497 - 1503.

Spanswick, VJ; Cummings, J; Smyth, JF; (1998) Current issues in the enzymology of mitomycin C metabolic activation. GEN PHARMACOL-VASC S , 31 (4) 539 - 544.

Stein, R; (1998) SH2 and SH3 domains. Unraveling signaling networks with peptide antagonists. Methods Mol Biol , 88 pp. 187-195. 10.1385/0-89603-487-9:187.

Sunters, A; Grimaldi, KA; Souhami, RL; Hartley, JA; (1998) Gene and human tumour cell line specific differences in nitrogen mustard induced DNA alkylation and interstrand crosslinking frequencies. NUCLEIC ACIDS RES , 26 (24) 5617 - 5623. Gold open access

T

Thatcher, N; Lee, SM; Woll, PJ; Middleton, M; Anderson, H; Burt, P; Stout, R; (1998) Dose intensity in small cell lung cancer. Seminars in Oncology , 25 (2) pp. 12-18.

Tilby, MJ; McCartney, H; Gould, KA; O'Hare, CC; Hartley, JA; Hall, AG; Golding, BT; (1998) A monofunctional derivative of melphalan: Preparation, DNA alkylation products, and determination of the specificity of monoclonal antibodies that recognize melphalan-DNA adducts. CHEM RES TOXICOL , 11 (10) 1162 - 1168.

Tolner, B; Roy, K; Sirotnak, FM; (1998) Structural analysis of the human RFC-1 gene encoding a folate transporter reveals multiple promoters and alternatively spliced transcripts with 5 ' end heterogeneity. GENE , 211 (2) 331 - 341.

V

Varrault, A; Ciani, E; Apiou, F; Bilanges, B; Hoffmann, A; Pantaloni, C; Bockaert, J; (1998) hZAC encodes a zinc finger protein with antiproliferative properties and maps to a chromosomal region frequently lost in cancer. Proc Natl Acad Sci U S A , 95 (15) pp. 8835-8840.

W

Watson, R; Boxer, GM; Jones, A; (1998) Quantitation of CEA and oestrogen receptor expression in human breast cancers by radioimmunoluminography. BRIT J CANCER , 78 59 - 59.

Whelan, JS; (1998) Bone tumours- Diagnosis, management and prognosis. Current Paediatrics , 8 pp. 31-36.

Whelan, JS; Burcombe, RJ; Cassoni, AM; (1998) Systematic review of prophylactic lung irradiation in Osteosarcoma and Ewing's sarcoma. In:

Z

Zilch, CF; Walker, AM; Timon, M; Goff, LK; Wallace, DL; Beverley, PCL; (1998) A point mutation within CD45 exon A is the cause of variant CD45RA splicing in humans. EUR J IMMUNOL , 28 (1) 22 - 29.

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