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Number of items: 64.


Alamartine, E; Stauss, HJ; Beverley, PCL; (1997) Both ICAM-1 and B7.1 are required to convert non-stimulatory keratinocytes into T cell-stimulating APCs. EUR J DERMATOL , 7 (7) 481 - 486.

Atra, A; Whelan, JS; Calvagna, V; Shankar, AG; Ashley, S; Shepherd, V; Souhami, RL; (1997) High-dose busulphan/melphalan with autologous stem cell rescue in Ewing's sarcoma. Bone Marrow Transplant , 20 (10) pp. 843-846. 10.1038/sj.bmt.1700992.


Bauknecht, T; Lueck, HJ; Calvert, H; Kreienberg, R; Pastovic, R; (1997) Topotecan: A ''compassionate use'' study in patients with advanced epithelial ovarian cancer refractory to other therapies. EUR J CANCER , 33 535 - 535.

Begent, RHJ; Chester, KA; (1997) Single-chain Fv antibodies for targeting cancer therapy. Biochemical Society Transactions , 25 (2) pp. 715-717.

Begent, RHJ; Chester, KA; (1997) Single-chain Fv antibodies for targeting cancer therapy. Biochemical Society Transactions. pp. 715-717.

Begent, RHJ; Chester, KA; Pedley, RB; Sharma, SJ; Robson, L; Bhatia, J; (1997) Novel antibody-based fusion proteins in cancer treatment. In: EUR J CANCER. (pp. 87 - 87). PERGAMON-ELSEVIER SCIENCE LTD

Beith, J; Hartley, J; Darling, J; Souhami, R; (1997) DNA interstrand cross-linking and cytotoxicity induced by chloroethylnitrosoureas and cisplatin in human glioma cell lines which vary in cellular concentration of O-6-alkylguanine-DNA alkyltransferase. BRITISH JOURNAL OF CANCER , 75 (4) pp. 500-505. 10.1038/bjc.1997.87.

Blakey, DC; Burke, PJ; Davies, DH; Dowell, RI; East, SJ; Melton, RG; NiculescuDuvaz, IA; ... Springer, CJ; + view all (1997) XD2767, an improved system for antibody-directed enzyme prodrug therapy that results in tumour regressions in colorectal tumour xenografts. EUROPEAN JOURNAL OF CANCER , 33 p. 88.

Bower, M; Newlands, ES; Bleehen, NM; Brada, M; Begent, RJH; Calvert, H; Colquhoun, I; ... Brampton, MH; + view all (1997) Multicentre CRC phase II trial of temozolomide in recurrent or progressive high-grade glioma. CANCER CHEMOTH PHARM , 40 (6) 484 - 488.

Bridgewater, JA; Knox, RJ; Pitts, JD; Collins, MK; Springer, CJ; (1997) The bystander effect of the nitroreductase CB 1954 enzyme prodrug system is due to a cell-permeable metabolite. HUMAN GENE THERAPY , 8 (6) pp. 709-717. 10.1089/hum.1997.8.6-709.

Bridgewater, JA; Rustin, GJS; (1997) Pseudo-Meigs' syndrome secondary to an ovarian germ cell tumor. GYNECOLOGIC ONCOLOGY , 66 (3) pp. 539-541. 10.1006/gyno.1997.4822.

Brooks, N; Hartley, JA; Simpson, JE; Wright, SR; Woo, S; Centioni, S; Fontaine, MD; ... Lee, M; + view all (1997) Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: Synthesis, DNA binding and cytotoxicity studies. BIOORGAN MED CHEM , 5 (8) 1497 - 1507.

Brooks, N; Lee, M; Wright, SR; Woo, S; Centioni, S; Hartley, JA; (1997) Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus. ANTI-CANCER DRUG DES , 12 (7) 591 - 606.


Cacchione, S; Cerone, MA; Savino, M; (1997) In vitro low propensity to form nucleosomes of four telomeric sequences. FEBS Lett , 400 (1) pp. 37-41.

Calvert, AH; (1997) A review of the pharmacokinetics and pharmacodynamics of combination carboplatin/paclitaxel. Semin Oncol , 24 (1 Suppl ) S2-85-S2-90-.

Calvert, AH; (1997) The use of pharmacokinetics to improve the treatment of ovarian cancer: combination paclitaxel (Taxol(R))carboplatin. INT J GYNECOL CANCER , 7 14 - 17.

Calvert, H; Kaye, S; Osborne, R; Sikora, K; Thomas, H; (1997) Good manners for the pharmaceutical industry. LANCET , 350 (9074) 371 - 371.

Chao, D; vonSchlippe, M; Harland, SJ; (1997) A phase II study of continuous infusion 5-fluorouracil (5-FU) with epirubicin and cisplatin in metastatic, hormone-resistant prostate cancer: an active new regimen. EUROPEAN JOURNAL OF CANCER , 33 (8) pp. 1230-1233. 10.1016/S0959-8049(97)00097-X.

Chiao, JH; Roy, K; Tolner, B; Yang, CH; Sirotnak, FM; (1997) RFC-1 gene expression regulates folate absorption in mouse small intestine. J BIOL CHEM , 272 (17) 11165 - 11170. Gold open access


Dhawan, RT; Bomanji, J; Waddington, W; Whelan, J; Pringle, J; Souhami, R; Ell, PJ; (1997) Correlation of serial and quantitative thallium scans with histological response to neoadjuvant chemotherapy in osteosarcoma. In: (pp. p. 314).

Dhawan, RT; Bomanji, J; Waddington, W; Whelan, J; Pringle, J; Souhami, R; Ell, PJ; (1997) Correlation of serial and quantitative thallium scans with histological response to neoadjuvant chemotherapy in osteosarcoma - methodological aspects and preliminary results. In: (pp. p. 917).

Domin, J; Pages, F; Volinia, S; Rittenhouse, SE; Zvelebil, MJ; Stein, RC; Waterfield, MD; (1997) Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin. BIOCHEMICAL JOURNAL , 326 pp. 139-147. 10.1042/bj3260139.

Douek, M; Davidson, T; HallCraggs, MA; Stein, R; Taylor, I; (1997) Assessment of response to treatment during chemotherapy for breast cancer. A new role for breast MRI? In: BREAST. (pp. 319 - 320). CHURCHILL LIVINGSTONE


Eagle, KF; Chester, KA; Boxer, GM; Pedley, RBAB; cancer, RHJPOACA-NFFUITOSCL; (1997) Quantitation of radiolabeled antibody distribution in tumour bearing nude mice using radioluminography. In: (Proceedings) Proceedings BACR, Br J Cancer. (pp. 62-).

Estlin, EJ; Balmanno, K; Calvert, AH; Hall, AG; Lunec, J; Newell, DR; Pearson, ADJ; (1997) The relationship between intrinsic thymidylate synthase expression and sensitivity to THYMITAQ (TM) in human leukaemia and colorectal carcinoma cell lines. BRIT J CANCER , 76 (12) 1579 - 1585.


Foxall, PJD; Singer, JM; Hartley, JM; Neild, GH; Lapsley, M; Nicholson, JK; Souhami, RL; (1997) Urinary proton magnetic resonance studies of early ifosfamide-induced nephrotoxicity and encephalopathy. CLIN CANCER RES , 3 (9) 1507 - 1518.


Grimaldi, KA; Hartley, JA; (1997) PCR-based methods for detecting DNA damage and its repair at the subgene and single nucleotide levels in cells. Methods Mol Biol , 90 pp. 157-180. 10.1385/0-89603-447-X:157.


Hartley, JA; (1997) Specific DNA sequences - A new target? EUR J CANCER , 33 1016 - 1016.

Hartley, JA; OHare, CC; Baumgart, J; (1997) DNA alkylation and interstrand crosslinking by treosulfan. EUR J CANCER , 33 792 - 792.

Hartley, JA; Wyatt, MD; (1997) Determination of the DNA sequence specificity of alkylation damage using cleavage-based assays. Methods Mol Biol , 90 pp. 147-156. 10.1385/0-89603-447-X:147.

Helbert, MR; Walter, J; LAge, J; Beverley, PCL; (1997) HIV infection of CD45RA(+) and CD45RO(+) CD4(+) T cells. CLIN EXP IMMUNOL , 107 (2) 300 - 305.

Hochhauser, D; (1997) Arsenic compound effective in leukaemia. The Lancet , 351 p. 1037.

Hochhauser, D; (1997) Colon cancer genotypes change in two ways. LANCET , 349 (9059) 1151 - 1151.

Hochhauser, D; (1997) Modulation of chemosensitivity through altered expression of cell cycle regulatory genes in cancer. ANTI-CANCER DRUG , 8 (10) 903 - 910.

Hochhauser, D; (1997) Molecular biologists map pathways to gastrointestinal cancer. The Lancet , 351 p. 1109.

Holford, J; Raynaud, F; Murrer, BA; Grimaldi, K; Hartley, JA; Abrams, M; Kelland, LR; (1997) Chemical, biochemical and pharmacological activity of the novel sterically hindered platinum co-ordination complex, cis-[amminedichloro(2-methylpyridine)] platinum(II) (AMD473). Anti-Cancer Drug Design , 13 pp. 1-18.


Johnson, N; Ng, TTC; Parkin, JM; (1997) Camptothecin causes cell cycle perturbations within T-lymphoblastoid cells followed by dose dependent induction of apoptosis. LEUKEMIA RESEARCH , 21 (10) pp. 961-972. 10.1016/S0145-2126(97)00077-5.


Kakouri, E; Whelan, JS; Coltart, S; Smith, MEF; Souhami, RL; (1997) Multi-focal, multi-centric angiosarcoma of bone. Sarcoma , 1 (3-4) pp. 183-187. 10.1080/13577149778290. Gold open access

Koberle, B; Grimaldi, KA; Sunters, A; Hartley, JA; Kelland, LR; Masters, JRW; (1997) DNA repair capacity and cisplatin sensitivity of human testis tumour cells. INT J CANCER , 70 (5) 551 - 555.


Li, WW; Fan, JG; Hochhauser, D; Bertino, JR; (1997) Overexpression of p21(waf1) leads to increased inhibition of E2F-1 phosphorylation and sensitivity to anticancer drugs in retinoblastoma-negative human sarcoma cells. CANCER RES , 57 (11) 2193 - 2199.

Ligueros, M; Jeoung, D; Tang, B; Hochhauser, D; Reidenberg, MM; Sonenberg, M; (1997) Gossypol inhibition of mitosis, cyclin D1 and Rb protein in human mammary cancer cells and cyclin-D1 transfected human fibrosarcoma cells. BRIT J CANCER , 76 (1) 21 - 28.


Martin, J; Stribbling, SM; Poon, GK; Begent, RHJ; Napier, M; Sharma, SK; Springer, CJ; (1997) Antibody-directed enzyme prodrug therapy: Pharmacokinetics and plasma levels of prodrug and drug in a phase I clinical trial. CANCER CHEMOTHERAPY AND PHARMACOLOGY , 40 (3) pp. 189-201. 10.1007/s002800050646.

Masters, JRW; Know, RJ; Hartley, JA; Kelland, LR; Hendriks, HR; Connors, T; (1997) KW-2149 (7-N-[2-[Y-L-glutamylamino]ethyldithioethyl]mitomycin C) - A new mitomycin C analogue activated by serum. BIOCHEM PHARMACOL , 53 (3) 279 - 285.

Mayer, A; Boxer, G; OMalley, D; Chester, K; Davidson, B; Winslet, MC; Hilson, AJW; (1997) Phase I study of radioimmunoguided surgery (RIGS) with anti-CEA single chain Fv antibody in colorectal cancer. EUR J CANCER , 33 724 - 724.


Ng, TTC; Kanner, SB; Humphries, MJ; Wickremasinghe, RG; Nye, KE; Anderson, J; Khoo, SH; (1997) The integrin-triggered rescue of T lymphocyte apoptosis is blocked in HIV-1-infected individuals. J IMMUNOL , 158 (6) 2984 - 2999.

Ng, TTC; Kanner, SB; Humphries, MJ; Wickremasinghe, RG; Nye, KE; Anderson, J; Morrow, WJW; (1997) Dysfunctional focal adhesion kinase (pp125(FAK)) expression in HIV-infected donor T-cells. BIOCHEM SOC T , 25 (2) S219 - S219.


Puvvada, MS; Forrow, SA; Hartley, JA; Stephenson, P; Gibson, I; Jenkins, TC; Thurston, DE; (1997) Inhibition of bacteriophage T7 RNA polymerase in vitro transcription by DNA-binding pyrrolo[2,1-c][1,4]benzodiazepines. BIOCHEMISTRY-US , 36 (9) 2478 - 2484.


Riordan, FA; Ng, T; Mengubas, K; Hoffbrand, AV; Mehta, AB; Wickremasinghe, RG; (1997) Irradiation of HL60 promyelocytic and chronic lymphocytic leukaemic (CLL) cells results in a rapid and transient increase in PP2A-like activity. EXP HEMATOL , 25 (8) 81 - 81.


Sharma, SK; Bhatia, J; Pedley, RB; Read, DA; Michael, P; Boden, RW; Chester, KA; (1997) Biodistribution of enzyme activity of a fusion protein for use in ADEPT. In: (pp. p. 48).

Short, S; (1997) UNSPECIFIED In: (Proceedings) The British Oncological Association.

Short, S; (1997) UNSPECIFIED In: (Proceedings) British Institute of Radiology 'New Therapeutic Approaches'.

Siddiqui, N; Boddy, AV; Thomas, HD; Bailey, NP; Robson, L; Lind, MJ; Calvert, AH; (1997) A clinical and pharmacokinetic study of the combination of carboplatin and paclitaxel for epithelial ovarian cancer. BRIT J CANCER , 75 (2) 287 - 294.

Stribbling, SM; Martin, J; Pedley, RB; Boden, JA; Sharma, SK; Springer, CJ; (1997) Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft. Cancer Chemotherapy and Pharmacology , 40 (4) pp. 277-284. 10.1007/s002800050659.

Stribbling, SM; Martin, J; Pedley, RB; Boden, JA; Sharma, SK; Springer, CJ; (1997) Biodistribution of an antibody-enzyme conjugate for antibody-directed enzyme prodrug therapy in nude mice bearing a human colon adenocarcinoma xenograft. CANCER CHEMOTH PHARM , 40 (4) 277 - 284.

Swanton, C; Mann, DJ; Fleckenstein, B; Neipel, F; Peters, G; Jones, N; (1997) Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins. NATURE , 390 (6656) pp. 184-187.


Tolner, B; Poolman, B; Konings, WN; (1997) Adaptation of microorganisms and their transport systems to high temperatures. COMP BIOCHEM PHYS A , 118 (3) 423 - 428.

Tolner, B; Roy, K; Sirotnak, FM; (1997) Organization, structure and alternate splicing of the murine RFC-1 gene encoding a folate transporter. GENE , 189 (1) 1 - 7.


Vanhaesebroeck, B; Leevers, SJ; Panayotou, G; Waterfield, MD; (1997) Phosphoinositide 3-kinases: A conserved family of signal transducers. TRENDS IN BIOCHEMICAL SCIENCES , 22 (7) pp. 267-272. 10.1016/S0968-0004(97)01061-X.

Vanhaesebroeck, B; Welham, MJ; Kotani, K; Stein, R; Warne, PH; Zvelebil, MJ; Higashi, K; ... Waterfield, MD; + view all (1997) p110 delta, a novel phosphoinositide 3-kinase in leukocytes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA , 94 (9) pp. 4330-4335. 10.1073/pnas.94.9.4330.


Wanders, J; vanOosterom, AT; Gore, M; Calvert, AH; Huinink, WWT; Hansen, HH; Wissel, P; (1997) A phase II study with GI147211 in ovarian cancer. EUR J CANCER , 33 528 - 528.

Whelan, JS; (1997) Osteosarcoma. In: UNSPECIFIED (1611 - 1618). PERGAMON-ELSEVIER SCIENCE LTD

Whelan, JS; (1997) Paediatric Update - Osteosarcoma. European Journal of Cancer , 33 pp. 1611-1618.

Wyatt, MD; Lee, M; Hartley, JA; (1997) Alkylation specificity for a series of distamycin analogues that tether chlorambucil. ANTI-CANCER DRUG DES , 12 (1) 49 - 60.

Wyatt, MD; Lee, M; Hartley, JA; (1997) The sequence specificity of alkylation for a series of benzoic acid mustard and imidazole-containing distamycin analogues: The importance of local sequence conformation. NUCLEIC ACIDS RES , 25 (12) 2359 - 2364. Gold open access

This list was generated on Sun Aug 18 04:47:03 2019 BST.