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Number of items: 49.

A

ABBASI, AM; CHESTER, KA; MACPHERSON, AJS; BOXER, GM; BEGENT, RHJ; MALCOLM, ADB; (1992) LOCALIZATION OF CEA MESSENGER-RNA BY INSITU HYBRIDIZATION IN NORMAL COLONIC MUCOSA AND COLORECTAL ADENOCARCINOMAS. J PATHOL , 168 (4) 405 - 411.

Abbasi, AM; Chester, KA; Macpherson, AJS; Boxer, GM; Begent, RHJ; Green, AJ; Malcolm, DB; (1992) Localization of cea messenger RNA by in situ hybridization in normal colonic mucosa and colorectal adenocarcinomas. The Journal of Pathology , 168 (4) pp. 404-411.

B

BISSET, GMF; PAWELCZAK, K; JACKMAN, AL; CALVERT, AH; HUGHES, LR; (1992) SYNTHESES AND THYMIDYLATE SYNTHASE INHIBITORY ACTIVITY OF THE POLY-GAMMA-GLUTAMYL CONJUGATES OF N-[5-[N-(3,4-DIHYDRO-2-METHYL-4-OXOQUINAZOLIN-6-YLMETHYL)-N-METHYLAMINO]-2-THENOYL]-L-GLUTAMIC ACID (ICI D1694) AND OTHER QUINAZOLINE ANTIFOLATES. J MED CHEM , 35 (5) 859 - 866.

BOSE, DS; THOMPSON, AS; CHING, JS; HARTLEY, JA; BERARDINI, MD; JENKINS, TC; NEIDLE, S; ... THURSTON, DE; + view all (1992) RATIONAL DESIGN OF A HIGHLY EFFICIENT IRREVERSIBLE DNA INTERSTRAND CROSS-LINKING AGENT BASED ON THE PYRROLOBENZODIAZEPINE RING-SYSTEM. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY , 114 (12) pp. 4939-4941. 10.1021/ja00038a089.

BOSE, DS; THOMPSON, AS; SMELLIE, M; BERARDINI, MD; HARTLEY, JA; JENKINS, TC; NEIDLE, S; (1992) EFFECT OF LINKER LENGTH ON DNA-BINDING AFFINITY, CROSS-LINKING EFFICIENCY AND CYTOTOXICITY OF C8-LINKED PYRROLOBENZODIAZEPINE DIMERS. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS (20) pp. 1518-1520. 10.1039/c39920001518.

BOWER, M; STEIN, R; EVANS, TRJ; HEDLEY, A; PERT, P; COOMBES, RC; (1992) A DOUBLE-BLIND-STUDY OF THE EFFICACY OF METRONIDAZOLE GEL IN THE TREATMENT OF MALODOROUS FUNGATING TUMORS. EUROPEAN JOURNAL OF CANCER , 28A (4-5) pp. 888-889. 10.1016/0959-8049(92)90142-O.

BOXER, GM; BEGENT, RHJ; KELLY, AMB; SOUTHALL, PJ; BLAIR, SB; THEODOROU, NA; DAWSON, PM; (1992) FACTORS INFLUENCING VARIABILITY OF LOCALIZATION OF ANTIBODIES TO CARCINOEMBRYONIC ANTIGEN (CEA) IN PATIENTS WITH COLORECTAL-CARCINOMA - IMPLICATIONS FOR RADIOIMMUNOTHERAPY. BRIT J CANCER , 65 (6) 825 - 831.

C

Calvert, AH; Newell, DR; Gore, ME; (1992) Future directions with carboplatin: can therapeutic monitoring, high-dose administration, and hematologic support with growth factors expand the spectrum compared with cisplatin? Semin Oncol , 19 (1 Suppl ) pp. 155-163.

Chester, KAB; R, HJ; (1992) 8th International Hammersmith Meeting On Advances in application of monoclonal-antibodies in clinical oncology. European Journal of Cancer , 28A pp. 606-608.

D

DOWSETT, M; MEHTA, A; KING, N; SMITH, IE; POWLES, TJ; STEIN, RC; COOMBES, RC; (1992) AN ENDOCRINE AND PHARMACOKINETIC STUDY OF 4 ORAL DOSES OF FORMESTANE IN POSTMENOPAUSAL BREAST-CANCER PATIENTS. EUROPEAN JOURNAL OF CANCER , 28A (2-3) pp. 415-420. 10.1016/S0959-8049(05)80065-6.

DOWSETT, M; STEIN, RC; COOMBES, RC; (1992) AROMATIZATION INHIBITION ALONE OR IN COMBINATION WITH GNRH AGONISTS FOR THE TREATMENT OF PREMENOPAUSAL BREAST-CANCER PATIENTS. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY , 43 (1-3) pp. 155-159. 10.1016/0960-0760(92)90201-S.

E

EVANS, TRJ; STEIN, RC; FORD, HT; GAZET, JC; CHAMBERLAIN, GV; COOMBES, RC; (1992) LACTIC-ACIDOSIS - A PRESENTATION OF METASTATIC BREAST-CANCER ARISING IN PREGNANCY. CANCER , 69 (2) pp. 453-456. 10.1002/1097-0142(19920115)69:2<453::AID-CNCR2820690230>3.0.CO;2-N.

F

FISHER, RA; NEWLANDS, ES; JEFFREYS, AJ; BOXER, GM; BEGENT, RHJ; RUSTIN, GJS; BAGSHAWE, KD; (1992) GESTATIONAL AND NONGESTATIONAL TROPHOBLASTIC TUMORS DISTINGUISHED BY DNA ANALYSIS. CANCER , 69 (3) 839 - 845.

FISHER, RA; PARADINAS, FJ; NEWLANDS, ES; BOXER, GM; (1992) GENETIC-EVIDENCE THAT PLACENTAL SITE TROPHOBLASTIC TUMORS CAN ORIGINATE FROM A HYDATIDIFORM MOLE OR A NORMAL CONCEPTUS. BRIT J CANCER , 65 (3) 355 - 358.

FOSTER, BJ; NEWELL, DR; GRAHAM, MA; GUMBRELL, LA; JENNS, KE; KAYE, SB; CALVERT, AH; (1992) PHASE-I TRIAL OF THE ANTHRAPYRAZOLE CI-941 - PROSPECTIVE EVALUATION OF A PHARMACOKINETICALLY GUIDED DOSE-ESCALATION. EUROPEAN JOURNAL OF CANCER , 28A (2-3) 463 - 469.

G

GRAHAM, MA; NEWELL, DR; FOSTER, BJ; GUMBRELL, LA; JENNS, KE; CALVERT, AH; (1992) CLINICAL PHARMACOKINETICS OF THE ANTHRAPYRAZOLE CI-941 - FACTORS COMPROMISING THE IMPLEMENTATION OF A PHARMACOKINETICALLY GUIDED DOSE ESCALATION SCHEME. CANCER RES , 52 (3) 603 - 609.

Gupta, RK; Whelan, JS; Lister, TA; Young, BD; Bodmer, JG; (1992) Direct sequence analysis of the t(14;18) chromosomal translocation in Hodgkin's disease. Blood , 79 (8) pp. 2084-2088.

H

HARRIS, AL; HOCHHAUSER, D; (1992) MECHANISMS OF MULTIDRUG RESISTANCE IN CANCER-TREATMENT. ACTA ONCOLOGICA , 31 (2) 205 - 213.

HARTLEY, JA; BINGHAM, JP; SOUHAMI, RL; (1992) DNA-SEQUENCE SELECTIVITY OF GUANINE-N7 ALKYLATION BY NITROGEN MUSTARDS IS PRESERVED IN INTACT-CELLS. NUCLEIC ACIDS RES , 20 (12) 3175 - 3178. Gold open access

HOCHHAUSER, D; STANWAY, CA; HARRIS, AL; HICKSON, ID; (1992) CLONING AND CHARACTERIZATION OF THE 5'-FLANKING REGION OF THE HUMAN TOPOISOMERASE-II-ALPHA GENE. J BIOL CHEM , 267 (26) 18961 - 18965. Gold open access

HOLLEY, JL; MATHER, A; WHEELHOUSE, RT; CULLIS, PM; HARTLEY, JA; BINGHAM, JP; COHEN, GM; (1992) TARGETING OF TUMOR-CELLS AND DNA BY A CHLORAMBUCIL-SPERMIDINE CONJUGATE. CANCER RESEARCH , 52 (15) pp. 4190-4195.

J

Johnson, PWM; Whelan, JS; Longhurst, S; Norton, A; Matthews, J; Rohatiner, AZS; Lister, TA; (1992) B-2 microglobulin (B-2M): a prognostic factor in diffuse aggressive non-Hodgkin's lymphomas. In:

K

KAMB, A; MOORE, JF; CALVERT, AH; STROUD, RM; (1992) STRUCTURAL BASIS FOR RECOGNITION OF POLYGLUTAMYL FOLATES BY THYMIDYLATE SYNTHASE. BIOCHEMISTRY-US , 31 (41) 9883 - 9890.

KONINGS, WN; TOLNER, B; SPEELMANS, G; ELFERINK, MGL; DEWIT, JG; DRIESSEN, AJM; (1992) ENERGY TRANSDUCTION AND TRANSPORT PROCESSES IN THERMOPHILIC BACTERIA. J BIOENERG BIOMEMBR , 24 (6) 601 - 609.

M

Macpherson, AJS; Chester, KA; Robson, L; Bjarnson, I; Malcolm, ADB; Peters, TJ; (1992) Increased expression of C-MYC protooncogene in biopsies of ulcerative-colitis and Crohns colitis. Gut , 33 (5) pp. 651-656.

Macpherson, AJS; Mayall, TP; Chester, KA; Abbasi, A; Forgacs, I; Malcolm, ADB; Peters, TJ; (1992) Mitochondrial gene-expression in the human gastrointestinal-tract. Journal of Cell Science , 102 (2) pp. 307-314.

O

OCONNOR, BM; JACKMAN, AL; CROSSLEY, PH; FREEMANTLE, SE; LUNEC, J; CALVERT, AH; (1992) HUMAN LYMPHOBLASTOID-CELLS WITH ACQUIRED-RESISTANCE TO C2-DESAMINO-C2-METHYL-N-10-PROPARGYL-5,8-DIDEAZAFOLIC ACID - A NOVEL FOLATE-BASED THYMIDYLATE SYNTHASE INHIBITOR. CANCER RES , 52 (5) 1137 - 1143.

R

RESZKA, KJ; BILSKI, P; CHIGNELL, CF; HARTLEY, JA; KHAN, N; SOUHAMI, RL; MENDONCA, AJ; (1992) PHOTOSENSITIZATION BY ANTICANCER AGENTS .11. MECHANISMS OF PHOTOSENSITIZATION OF HUMAN LEUKEMIC-CELLS BY DIAMINOANTHRAQUINONES - SINGLET OXYGEN AND RADICAL REACTIONS. J PHOTOCH PHOTOBIO B , 15 (4) 317 - 335.

ROBSON, CN; HOCHHAUSER, D; CRAIG, R; RACK, K; BUCKLE, VJ; HICKSON, ID; (1992) STRUCTURE OF THE HUMAN DNA-REPAIR GENE HAP1 AND ITS LOCALIZATION TO CHROMOSOME 14Q 11 2-12. NUCLEIC ACIDS RES , 20 (17) 4417 - 4421. Gold open access

Rohatiner, AZS; Bassan, R; Batista, R; Kingston, JE; Amess, J; Carter, M; Oza, AM; ... Lister, TA; + view all (1992) UNSPECIFIED In: (Proceedings) High dose cytosine arabinoside in the treatment of acute lymphoblastic leukaemia. Meeting Proceedings, Acute Leukemias III - Prognostic factors and treatment strategies,. : Munster.

Rohatiner, AZS; Battista, R; Bassan, R; Love, S; Oza, AM; Whelan, JS; Lim, J; ... D'Emillio, ; + view all (1992) Short term therapy for acute myelogenous leukaemia. Leukemia , 6 (S2) pp. 85-88.

S

SCHULZEOSTHOFF, K; BAKKER, AC; VANHAESEBROECK, B; BEYAERT, R; JACOB, WA; FIERS, W; (1992) CYTOTOXIC ACTIVITY OF TUMOR-NECROSIS-FACTOR IS MEDIATED BY EARLY DAMAGE OF MITOCHONDRIAL FUNCTIONS - EVIDENCE FOR THE INVOLVEMENT OF MITOCHONDRIAL RADICAL GENERATION. JOURNAL OF BIOLOGICAL CHEMISTRY , 267 (8) pp. 5317-5323.

SHARMA, SK; BAGSHAWE, KD; MELTON, RG; SHERWOOD, RF; (1992) HUMAN IMMUNE-RESPONSE TO MONOCLONAL-ANTIBODY ENZYME CONJUGATES IN ADEPT PILOT CLINICAL-TRIAL. In: (Proceedings) 8th International Hammersmith Meeting on Advances in the Applications of Monoclonal Antibodies in Clinical Oncology. (pp. pp. 109-120). HUMANA PRESS INC

STEIN, RC; BOWER, M; LAW, M; BLISS, JM; BARTON, C; GAZET, JC; FORD, HT; (1992) MITOXANTRONE AND METHOTREXATE CHEMOTHERAPY WITH AND WITHOUT MITOMYCIN-C IN THE TREATMENT OF ADVANCED BREAST-CANCER - A RANDOMIZED CLINICAL-TRIAL. EUROPEAN JOURNAL OF CANCER , 28A (12) pp. 1963-1965. 10.1016/0959-8049(92)90237-V.

STEIN, RC; JOSEPH, AEA; MATLIN, SA; CUNNINGHAM, DC; FORD, HT; COOMBES, RC; (1992) A PRELIMINARY CLINICAL-STUDY OF GOSSYPOL IN ADVANCED HUMAN CANCER. CANCER CHEMOTHERAPY AND PHARMACOLOGY , 30 (6) pp. 480-482. 10.1007/BF00685601.

SUNTERS, A; SPRINGER, CJ; BAGSHAWE, KD; SOUHAMI, RL; HARTLEY, JA; (1992) THE CYTOTOXICITY, DNA CROSS-LINKING ABILITY AND DNA-SEQUENCE SELECTIVITY OF THE ANILINE MUSTARDS MELPHALAN, CHLORAMBUCIL AND 4-[BIS(2-CHLOROETHYL)AMINO] BENZOIC-ACID. BIOCHEM PHARMACOL , 44 (1) 59 - 64.

Smith, TA; Whelan, J; Parry, PJ; (1992) Detection of single-base mutations in a mixed population of cells: a comparison of SSCP and direct sequencing. Genet Anal Tech Appl , 9 (5-6) pp. 143-145.

T

THORNTON, TJ; JACKMAN, AL; MARSHAM, PR; OCONNOR, BM; BISHOP, JAM; CALVERT, AH; (1992) QUINAZOLINE ANTIFOLATE THYMIDYLATE SYNTHASE INHIBITORS - DIFLUORO-SUBSTITUTED BENZENE-RING ANALOGS. J MED CHEM , 35 (12) 2321 - 2327.

TOLNER, B; POOLMAN, B; KONINGS, WN; (1992) CHARACTERIZATION AND FUNCTIONAL EXPRESSION IN ESCHERICHIA-COLI OF THE SODIUM PROTON GLUTAMATE SYMPORT PROTEINS OF BACILLUS-STEAROTHERMOPHILUS AND BACILLUS-CALDOTENAX. MOL MICROBIOL , 6 (19) 2845 - 2856.

TOLNER, B; POOLMAN, B; WALLACE, B; KONINGS, WN; (1992) REVISED NUCLEOTIDE-SEQUENCE OF THE GLTP GENE, WHICH ENCODES THE PROTON-GLUTAMATE-ASPARTATE TRANSPORT PROTEIN OF ESCHERICHIA-COLI K-12. J BACTERIOL , 174 (7) 2391 - 2393.

TOLNER, B; VANDERREST, ME; SPEELMANS, G; KONINGS, WN; (1992) SODIUM COUPLED TRANSPORT IN BACTERIA. In: QUAGLIARIELLO, E and PALMIERI, F, (eds.) MOLECULAR MECHANISMS OF TRANSPORT. (pp. 43 - 50). ELSEVIER SCIENCE PUBL B V

V

VANHAESEBROECK, B; DECOSTER, E; VANOSTADE, X; VANBLADEL, S; LENAERTS, A; VANROY, F; FIERS, W; (1992) EXPRESSION OF AN EXOGENOUS TUMOR-NECROSIS-FACTOR (TNF) GENE IN TNF-SENSITIVE CELL-LINES CONFERS RESISTANCE TO TNF-MEDIATED CELL-LYSIS. JOURNAL OF IMMUNOLOGY , 148 (9) pp. 2785-2794.

W

WILLEMS, JL; LANGENBERG, JP; VERSTRAETE, AG; DELOOSE, M; VANHAESEBROECK, B; GOETHALS, G; BELPAIRE, FM; ... COLARDYN, F; + view all (1992) PLASMA-CONCENTRATIONS OF PRALIDOXIME METHYLSULFATE IN ORGANOPHOSPHORUS POISONED PATIENTS. ARCHIVES OF TOXICOLOGY , 66 (4) pp. 260-266. 10.1007/BF02307171.

Whelan, JS; Davis, CL; Rohatiner, AZ; Leahy, M; MacCallum, PK; Gupta, RK; Matthews, J; ... Lister, TA; + view all (1992) Etoposide in combination with intermediate dose cytosine arabinoside (ID ARA C) given with the intention of further myeloablative therapy for the treatment of refractory or recurrent hematological malignancy. Hematol Oncol , 10 (2) pp. 87-94.

Whelan, JS; Smith, TA; Rohatiner, A; Lister, T; Meuth, M; (1992) A potential molecular basis of resistance to cytosine arabinoside in acute leukaemia. In:

Whelan, JS; Smith, TA; Rohatiner, AZS; Lister, TA; Meuth, M; (1992) UNSPECIFIED In: (Proceedings) Resistance to cytosine arabinoside: are mutations in CTP synthetase an important mechanism? Meeting Proceedings, Acute Leukemias III - Prognostic factors and treatment strategies,. : Munster.

Whelan, JS; Smith, TA; Rohatiner, AZS; Lister, TA; Meuth, M; (1992) Resistance to cytosine arabinoside: are mutations in CTP synthetase an important mechanism? In:

Whelan, JS; Stebbings, W; Owen, RA; Calne, R; Clark, PI; (1992) Successful treatment of a primary endodermal sinus tumor of the liver. Cancer , 70 (9) pp. 2260-2262. 10.1002/1097-0142(19921101)70:9<2260::aid-cncr2820700908>3.0.co;2-y.

Whelan, JS; van Dam, PA; Shepherd, JH; Slevin, ML; (1992) The treatment of microscopic residual ovarian cancer with intraperitoneal interferon: a clinical and flow cytometric study. Br J Obstet Gynaecol , 99 (7) pp. 615-617. 10.1111/j.1471-0528.1992.tb13833.x.

This list was generated on Sun Aug 18 04:47:59 2019 BST.