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Number of items: 52.

C

Castaldi, PJ; Cho, MH; Zhou, X; Qiu, W; Mcgeachie, M; Celli, B; Bakke, P; ... Hersh, CP; + view all (2015) Genetic control of gene expression at novel and established chronic obstructive pulmonary disease loci. HUMAN MOLECULAR GENETICS , 24 (4) pp. 1200-1210. 10.1093/hmg/ddu525.

Charidimou, A; Fox, Z; Werring, DJ; Song, M; (2015) Cerebral amyloid angiopathy research: on the verge of an explosion? INTERNATIONAL JOURNAL OF STROKE , 10 (5) E47-E48. 10.1111/ijs.12483.

Charidimou, A; Hong, YT; Jaeger, HR; Fox, Z; Aigbirhio, FI; Fryer, TD; Menon, DK; ... Baron, J-C; + view all (2015) White Matter Perivascular Spaces on Magnetic Resonance Imaging Marker of Cerebrovascular Amyloid Burden? STROKE , 46 (6) pp. 1707-1709. 10.1161/STROKEAHA.115.009090.

Charidimou, A; Shoamanesh, A; Wilson, D; Gang, Q; Fox, Z; Jaeger, HR; Benavente, OR; (2015) Cerebral microbleeds and postthrombolysis intracerebral hemorrhage risk Updated meta-analysis. NEUROLOGY , 85 (11) pp. 927-934. 10.1212/WNL.0000000000001923.

Choi, D; Fox, Z; Albert, T; Arts, M; Balabaud, L; Bunger, C; Buchowski, JM; ... Crockard, HA; + view all (2015) Prediction of Quality of Life and Survival After Surgery for Symptomatic Spinal Metastases: A Multicenter Cohort Study to Determine Suitability for Surgical Treatment. NEUROSURGERY , 77 (5) pp. 698-708. 10.1227/NEU.0000000000000907.

Cuff, S; Lewis, R; Jaffar, M; Knox, R; Weeks, I; (2015) Abstract 550: Evaluation of NQO1 as a potential diagnostic marker for bladder cancer. Presented at: UNSPECIFIED.

D

Derrett-Smith, E; Sobanski, V; Trinder, S; Gilbane, A; Iglarz, M; Abraham, D; Holmes, A; (2015) ENDOTHELIN RECEPTOR BLOCKADE PREVENTS DEVELOPMENT OF PULMONARY HYPERTENSION IN A MOUSE MODEL OF SCLERODERMA. In: (Proceedings) Annual Meeting of the British-Society-for-Rheumatology and British-Health-Professionals-in-Rheumatology. (pp. pp. 159-160). OXFORD UNIV PRESS

Derrett-Smith, EC; Sobanski, V; Gilbane, A; Trinder, S; Bauer, Y; Renault, B; Iglarz, M; ... Denton, CP; + view all (2015) Macitentan Responsiveness Supports the Validity of a Murine Model of Pulmonary Hypertension in Scleroderma Associated with Altered Tgfbeta/BMPR2 Signalling. ARTHRITIS & RHEUMATOLOGY , 67

Dickens, JA; Ordonez, A; Chambers, JE; Lomas, DA; Marciniak, SJ; (2015) MEASURING ER PROTEIN MOBILITY DURING ER FRAGMENTATION IN ALPHA-1-ANTITRYPSIN DEFICIENCY. In: (Proceedings) Winter Meeting of the British-Thoracic-Society. (pp. A71-A72). BMJ PUBLISHING GROUP

Dijkstra, AE; Boezen, HM; van den Berge, M; Vonk, JM; Hiemstra, PS; Barr, RG; Burkart, KM; ... Postma, DS; + view all (2015) Dissecting the genetics of chronic mucus hypersecretion in smokers with and without COPD. EUROPEAN RESPIRATORY JOURNAL , 45 (1) pp. 60-75. 10.1183/09031936.00093314.

Dijkstra, AE; Smolonska, J; van den Berge, M; Wijmenga, C; Zanen, P; Luinge, MA; Platteel, M; ... LifeLines Cohort Study, ; + view all (2015) Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study. PLoS One , 10 (5) , Article e0129524. 10.1371/journal.pone.0129524.

Donovan, JC; Holmes, AM; Wilson, PD; Norman, JT; (2015) EPIGENETIC MODULATION SUPPRESSES THE PRO-FIBROTIC FEATURES OF HUMAN AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE (ADPKD) FIBROBLASTS IN VITRO. In: (Proceedings) 52nd Congress of the European-Renal-Association-European-Dialysis-and-Transplant-Assocation. OXFORD UNIV PRESS

F

Falcone, MA; Murray, RM; Wiffen, BDR; O'Connor, JA; Russo, M; Kolliakou, A; Stilo, S; ... Jolley, S; + view all (2015) Jumping to conclusions, neuropsychological functioning, and delusional beliefs in first episode psychosis. Schizophr Bull , 41 (2) pp. 411-418. 10.1093/schbul/sbu104.

Feeney, M; Syed, F; Khan, K; Xu, S; Sully, K; Trinder, S; Wilson, P; ... Denton, CP; + view all (2015) Oncostatin M As a Potential Molecular Target in Systemic Sclerosis. ARTHRITIS & RHEUMATOLOGY , 67

G

Gang, Q; Bettencourt, C; Machado, PM; Fox, Z; Brady, S; Healy, E; Parton, M; ... Houlden, H; + view all (2015) The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. Neurobiology of Aging , 36 (4) 1766.e1-1766.e3. 10.1016/j.neurobiolaging.2014.12.039.

Gang, Q; Bettencourt, C; Machado, PM; Fox, Z; Brady, S; Healy, E; Parton, M; ... Muscle Study Group and the International IBM Genetics Consortium(#), ,; + view all (2015) The effects of an intronic polymorphism in TOMM40 and APOE genotypes in sporadic inclusion body myositis. Neurobiol Aging , 36 (4) 1766.e1 - 1766.e3. 10.1016/j.neurobiolaging.2014.12.039. Green open access
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Gilbane, AJ; Derrett-Smith, E; Trinder, SL; Good, RB; Pearce, A; Denton, CP; Holmes, AM; (2015) Impaired Bone Morphogenetic Protein Receptor II Signaling in a Transforming Growth Factor-beta-Dependent Mouse Model of Pulmonary Hypertension and in Systemic Sclerosis. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 191 (6) pp. 665-677. 10.1164/rccm.201408-1464OC.

Good, R; Trinder, SL; Denton, CP; Abraham, D; Holmes, AM; (2015) Blood Outgrowth Endothelial Cells Isolated from Systemic Sclerosis Patients Exhibit a Pro-Inflammatory Phenotype. ARTHRITIS & RHEUMATOLOGY , 67

Good, RB; Gilbane, AJ; Trinder, SL; Denton, CP; Coghlan, G; Abraham, DJ; Holmes, AM; (2015) Endothelial to Mesenchymal Transition Contributes to Endothelial Dysfunction in Pulmonary Artery Hypertension. American Journal of Pathology , 185 (7) pp. 1850-1858. 10.1016/j.ajpath.2015.03.019.

Gómez-Robles, A; Bermúdez de Castro, JM; Martinón-Torres, M; Prado-Simón, L; Arsuaga, JL; (2015) A geometric morphometric analysis of hominin lower molars: Evolutionary implications and overview of postcanine dental variation. J Hum Evol , 82 pp. 34-50. 10.1016/j.jhevol.2015.02.013.

Gmez-Robles, A; Hopkins, WD; Schapiro, SJ; Sherwood, CC; (2015) Relaxed genetic control of cortical organization in human brains compared with chimpanzees. Proc Natl Acad Sci U S A , 112 (48) pp. 14799-14804. 10.1073/pnas.1512646112.

H

Haq, I; Irving, JA; Saleh, AD; Dron, L; Regan-Mochrie, GI; Motamedi-Shad, N; Hurst, JR; ... Gooptu, B; + view all (2015) DEFICIENCY MUTATIONS OF alpha 1-ANTITRYPSIN DIFFERENTIALLY AFFECT FOLDING, FUNCTION AND POLYMERISATION. In: (Proceedings) Winter Meeting of the British-Thoracic-Society. (pp. A74-A74). BMJ PUBLISHING GROUP

Hobbs, BD; Hardin, M; Hawrylkiewicz, I; Sliwinski, P; Yim, J; Kim, WJ; Kim, DK; ... Cho, MH; + view all (2015) Coding Variant Associations With Lung Function And COPD Using An Exome Array. In: (Proceedings) International Conference of the American-Thoracic-Society (ATS). AMER THORACIC SOC

Horne, R; Bell, JI; Montgomery, JR; Ravn, MO; Tooke, JE; (2015) A new social contract for medical innovation. LANCET , 385 (9974) pp. 1153-1154.

Hull, EA; (2015) Antibody Conjugates via Disulfide Bridging: Towards therapeutic and diagnostic applications. Doctoral thesis, UCL (University College London). Green open access
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I

Irving, JA; Miranda, E; Haq, I; Perez, J; Kotov, VR; Faull, SV; Motamedi-Shad, N; (2015) An antibody raised against a pathogenic serpin variant induces mutant-like behaviour in the wild-type protein. Biochem J , 468 (1) pp. 99-108. 10.1042/BJ20141569. Green open access
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Irving, JA; Motamedi-Shad, N; Jagger, A; Faull, SV; Haq, I; Liedtke, M; Miranda, E; ... Lomas, DA; + view all (2015) Stability and structural change during the oligomerisation of alpha 1-antitrypsin. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS , 44 S206-S206.

J

Joseph, S; Iverson, P; Manohar, S; Fox, Z; Scott, SK; Husain, M; (2015) Precision of working memory for speech sounds. QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY , 68 (10) pp. 2022-2040. 10.1080/17470218.2014.1002799.

Joseph, S; Iverson, P; Manohar, S; Fox, Z; Scott, SK; Husain, M; (2015) Precision of working memory for speech sounds. Quarterly Journal of Experimental Psychology , 68 (10) pp. 2022-2040. 10.1080/17470218.2014.1002799.

L

Lee, JH; Cho, MH; Hersh, CP; McDonald, M-LN; Wells, JM; Dransfield, MT; Bowler, RP; ... Silverman, EK; + view all (2015) IREB2 and GALC Are Associated with Pulmonary Artery Enlargement in Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 52 (3) pp. 365-376. 10.1165/rcmb.2014-0210OC.

Lutz, SM; Cho, MH; Young, K; Hersh, CP; Castaldi, PJ; McDonald, M-L; Regan, E; ... Silverman, EK; + view all (2015) A genome-wide association study identifies risk loci for spirometric measures among smokers of European and African ancestry. BMC GENETICS , 16 (ARTN 138) 10.1186/s12863-015-0299-4.

Lthy, M; Wheldon, MC; Haji-Cheteh, C; Atobe, M; Bond, PS; O'Brien, P; Hubbard, RE; (2015) Lead-oriented synthesis: Investigation of organolithium-mediated routes to 3-D scaffolds and 3-D shape analysis of a virtual lead-like library. Bioorg Med Chem , 23 (11) pp. 2680-2694. 10.1016/j.bmc.2015.04.005.

M

Mahy, W; Plucinski, P; Jover, J; Frost, CG; (2015) Ruthenium-Catalyzed O- to S-Alkyl Migration: A Pseudoreversible Barton-McCombie Pathway. Angew Chem Int Ed Engl , 54 (37) pp. 10944-10948. 10.1002/anie.201505280.

Martorana, V; Irving, JA; Faull, SV; Haq, I; Noto, R; Lomas, DA; Manno, M; (2015) The structure of protein polymers, revealed by HPLC-SAXS experiments. EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS , 44 S103-S103.

Moriconi, C; Ordonez, A; Lupo, G; Gooptu, B; Irving, JA; Noto, R; Martorana, V; ... Miranda, E; + view all (2015) Interactions between N-linked glycosylation and polymerisation of neuroserpin within the endoplasmic reticulum. FEBS JOURNAL , 282 (23) pp. 4565-4579. 10.1111/febs.13517.

Murphy, C; Kelly, J; Hodsoll, J; Georgiou, E; Morgan, L; Rowson, C; Cole, V; ... Pickles, A; + view all (2015) KCTU randomisation and IMP management system (vol 14, pg 63, 2013). TRIALS , 16 (ARTN 338) 10.1186/s13063-015-0870-3.

N

Nyon, MP; Prentice, T; Day, J; Kirkpatrick, J; Sivalingam, GN; Levy, G; Haq, I; ... Thalassinos, K; + view all (2015) An integrative approach combining ion mobility mass spectrometry, X-ray crystallography, and nuclear magnetic resonance spectroscopy to study the conformational dynamics of α1 -antitrypsin upon ligand binding. Protein Science , 24 (8) pp. 1301-1312. 10.1002/pro.2706. Green open access
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O

Ordonez, A; Perez, J; Tan, L; Dickens, JA; Motamedi-Shad, N; Irving, JA; Haq, I; ... Lomas, DA; + view all (2015) A single-chain variable fragment intrabody prevents intracellular polymerization of Z alpha(1)-antitrypsin while allowing its antiproteinase activity. FASEB JOURNAL , 29 (6) pp. 2667-2678. 10.1096/fj.14-267351.

P

Partington, L; (2015) Development of a pressurised transmural decellularisation method for application in tissue engineering trachea. Doctoral thesis, UCL (University College London). Green open access
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Ponticos, M; Papaioannou, I; Xu, S; Holmes, AM; Khan, K; Denton, CP; Bou-Gharios, G; (2015) Failed degradation of JunB contributes to overproduction of type I collagen and development of dermal fibrosis in patients with systemic sclerosis. Arthritis Rheumatol , 67 (1) 243 - 253. 10.1002/art.38897. Green open access
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R

Ranieri, V; Barratt, H; Fulop, N; Rees, G; (2015) Clinical academics’ postdoctoral career development. BMJ: British Medical Journal , 351 (h6945) 10.1136/bmj.h6945. Green open access
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Ranieri, V; Madigan, K; Roche, E; Bainbridge, E; McGuinness, D; Tierney, K; Feeney, L; ... O'Donoghue, B; + view all (2015) Caregivers' perceptions of coercion in psychiatric hospital admission. Psychiatry Res , 228 (3) pp. 380-385. 10.1016/j.psychres.2015.05.079.

Rennard, SI; Locantore, N; Delafont, B; Tal-Singer, R; Silverman, EK; Vestbo, J; Miller, BE; ... Evaluation of COPD Longitudinally to Identify Predictive Surroga, ; + view all (2015) Identification of five chronic obstructive pulmonary disease subgroups with different prognoses in the ECLIPSE cohort using cluster analysis. Ann Am Thorac Soc , 12 (3) pp. 303-312. 10.1513/AnnalsATS.201403-125OC.

Riazi, A; Aspden, T; Walters, K; Rubin, GS; Ambler, G; Jichi, F; O'Driscoll, M; (2015) Improving psychological well-being in people recently diagnosed with visual impairment: A pilot randomised controlled trial of Problem-Solving Treatment for Visual Impairment (POSITIVE). In: (Proceedings) Annual Meeting of the Association-for-Research-in-Vision-and-Ophthalmology (ARVO). ASSOC RESEARCH VISION OPHTHALMOLOGY INC

S

Samanta, S; Saleh, AD; Gooptu, B; Marshall, A; Thorburn, D; Lomas, DA; Hurst, JR; (2015) SEVERITY OF LUNG BUT NOT LIVER DISEASE IMPACTS CARDIOVASCULAR RISK IN ALPHA-1 ANTITRYPSIN DEFICIENCY. In: (Proceedings) Winter Meeting of the British-Thoracic-Society. (pp. A55-A55). BMJ PUBLISHING GROUP

T

Tan, L; Perez, J; Mela, M; Miranda, E; Burling, KA; Rouhani, FN; DeMeo, DL; ... Lomas, DA; + view all (2015) Characterising the association of latency with ?(1)-antitrypsin polymerisation using a novel monoclonal antibody. Int J Biochem Cell Biol , 58 81 - 91. 10.1016/j.biocel.2014.11.005. Green open access
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Trinder, SL; Gilbane, A; Good, R; Derrett-Smith, EC; Denton, CP; Abraham, D; Holmes, AM; (2015) Bromodomain Inhibitor JQ1 Modulates Smooth Muscle Cell Switching and Ameliorates Chronic Hypoxia/SU5416-Induced Pulmonary Arterial Hypertension in Mice. ARTHRITIS & RHEUMATOLOGY , 67

V

van't Wout, EFA; van Schadewijk, A; Lomas, DA; Stolk, J; Marciniak, SJ; Hiemstra, PS; (2015) Function of monocytes and monocyte-derived macrophages in alpha(1)-antitrypsin deficiency. EUROPEAN RESPIRATORY JOURNAL , 45 (2) pp. 365-376. 10.1183/09031936.00046114.

W

Wan, ES; Qiu, W; Morrow, J; Beaty, TH; Hetmanski, J; Make, BJ; Lomas, DA; ... DeMeo, DL; + view all (2015) Genome-Wide Site-Specific Differential Methylation in the Blood of Individuals With Klinefelter Syndrome. MOLECULAR REPRODUCTION AND DEVELOPMENT , 82 (5) pp. 377-386. 10.1002/mrd.22483.

Wilke, S; Jones, PW; Muellerova, H; Vestbo, J; Tal-Singer, R; Franssen, FME; Agusti, A; ... Spruit, MA; + view all (2015) One-year change in health status and subsequent outcomes in COPD. THORAX , 70 (5) pp. 420-425. 10.1136/thoraxjnl-2014-205697.

Wilson, AA; Ying, L; Liesa, M; Segeritz, C-P; Mills, JA; Shen, SS; Jean, J; ... Kotton, DN; + view all (2015) Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells. Stem Cell Reports , 4 (5) pp. 873-885. 10.1016/j.stemcr.2015.02.021.

Y

Yonchuk, JG; Silverman, EK; Bowler, RP; Agusti, A; Lomas, DA; Miller, BE; Tal-Singer, R; (2015) Circulating Soluble Receptor for Advanced Glycation End Products (sRAGE) as a Biomarker of Emphysema and the RAGE Axis in the Lung. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 192 (7) pp. 785-792. 10.1164/rccm.201501-0137PP.

This list was generated on Sun Sep 17 04:43:30 2017 BST.