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Number of items: 66.


Agnelli, G; George, D; Fisher, WD; Kakkar, AK; Lassen, MR; Mismetti, P; Mouret, P; ... Turpie, AGG; + view all (2011) Ultra-low-molecular-weight Heparin (ULMWH) Semuloparin for Prevention of Venous Thromboembolism (VIE) in Cancer Patients Receiving Chemotherapy: Consistent Beneficial Effect Across Cancer Stage and Location Subgroups. In: (Proceedings) European Multidisciplinary Cancer Congress on Integrating Basic and Translational Science, Surgery, Radiotherapy, Medical oncology, Advocacy and Care. (pp. S222-S222). ELSEVIER SCI LTD


Bafadhel, M; McKenna, S; Terry, S; Mistry, V; Reid, C; Haldar, P; McCormick, M; ... Brightling, CE; + view all (2011) Acute Exacerbations of Chronic Obstructive Pulmonary Disease Identification of Biologic Clusters and Their Biomarkers. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 184 (6) pp. 662-671. 10.1164/rccm.201104-0597OC.

Bakke, PS; Zhu, G; Gulsvik, A; Kong, X; Agusti, AGN; Calverley, PMA; Donner, CF; ... Pillai, SG; + view all (2011) Candidate genes for COPD in two large data sets. EUROPEAN RESPIRATORY JOURNAL , 37 (2) pp. 255-263. 10.1183/09031936.00091709.

Belorgey, D; Irving, JA; Ekeowa, UI; Freeke, J; Roussel, BD; Miranda, E; Perez, J; ... Lomas, DA; + view all (2011) Characterisation of serpin polymers in vitro and in vivo. METHODS , 53 (3) pp. 255-266. 10.1016/j.ymeth.2010.11.008.

Ben Abdallah, NM-B; Fuss, J; Trusel, M; Galsworthy, MJ; Bobsin, K; Colacicco, G; Deacon, RMJ; ... Gass, P; + view all (2011) The puzzle box as a simple and efficient behavioral test for exploring impairments of general cognition and executive functions in mouse models of schizophrenia. Exp Neurol , 227 (1) pp. 42-52. 10.1016/j.expneurol.2010.09.008.

Bergmann, J-F; Lloret-Linares, C; Rami, A; Cohen, AT; Garay, RP; Kakkar, AK; Goldhaber, SZ; ... pour les investigateurs de l’étude Endorse France, ; + view all (2011) [Venous thromboembolism risk and prophylaxis in the acute hospital care setting (ENDORSE study): results obtained in France]. Presse Med , 40 (12 Pt 1) e528-e537. 10.1016/j.lpm.2011.06.023.

Brehm, JM; Hagiwara, K; Tesfaigzi, Y; Bruse, S; Mariani, TJ; Bhattacharya, S; Boutaoui, N; ... Celedon, JC; + view all (2011) Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. THORAX , 66 (12) pp. 1085-1090. 10.1136/thoraxjnl-2011-200017.


Castaldi, PJ; Cho, MH; Litonjua, AA; Bakke, P; Gulsvik, A; Lomas, DA; Anderson, W; ... Silverman, EK; + view all (2011) The Association of Genome-Wide Significant Spirometric Loci with Chronic Obstructive Pulmonary Disease Susceptibility. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 45 (6) pp. 1147-1153. 10.1165/rcmb.2011-0055OC.

Castaldi, PJ; Demeo, DL; Hersh, CP; Lomas, DA; Soerheim, IC; Gulsvik, A; Bakke, P; ... Silverman, EK; + view all (2011) Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. THORAX , 66 (10) pp. 903-909. 10.1136/thx.2010.146118.

Charlesworth, K; Galsworthy, MJ; Ernst, K; Irwin, R; Wismar, M; McKee, M; (2011) Health research in the European Union: over-controlled but under-measured? Eur J Public Health , 21 (4) pp. 404-406. 10.1093/eurpub/ckp212.

Ciuclan, L; Bonneau, O; Hussey, M; Duggan, N; Holmes, AM; Good, R; Stringer, R; ... Thomas, M; + view all (2011) A novel murine model of severe pulmonary arterial hypertension. American journal of respiratory and critical care medicine , 184 pp. 1171-1182.



Decousus, H; Tapson, VF; Bergmann, J-F; Chong, BH; Froehlich, JB; Kakkar, AK; Merli, GJ; ... Anderson, FA; + view all (2011) Factors at Admission Associated With Bleeding Risk in Medical Patients Findings From the IMPROVE Investigators. CHEST , 139 (1) pp. 69-79. 10.1378/chest.09-3081.

Dickens, JA; Lomas, DA; (2011) Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis. DRUG DESIGN DEVELOPMENT AND THERAPY , 5 pp. 391-405. 10.2147/DDDT.S14018.

Dickens, JA; Miller, BE; Edwards, LD; Silverman, EK; Lomas, DA; Tal-Singer, R; (2011) COPD association and repeatability of blood biomarkers in the ECLIPSE cohort. RESPIRATORY RESEARCH , 12 (ARTN 146) 10.1186/1465-9921-12-146.

Duvoix, A; Miranda, E; Perez, J; Sorensen, GL; Holmskov, U; Trapnell, BC; Madsen, J; ... Lomas, DA; + view all (2011) Evaluation of Full-length, Cleaved and Nitrosylated Serum Surfactant Protein D as Biomarkers for COPD. COPD-JOURNAL OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE , 8 (2) pp. 79-95. 10.3109/15412555.2011.558542.


Ekeowa, UI; Marciniak, SJ; Lomas, DA; (2011) alpha(1)-antitrypsin deficiency and inflammation. EXPERT REVIEW OF CLINICAL IMMUNOLOGY , 7 (2) pp. 243-252. 10.1586/ECI.10.95.


Foreman, MG; Kong, X; DeMeo, DL; Pillai, SG; Hersh, CP; Bakke, P; Gulsvik, A; ... Silverman, EK; + view all (2011) Polymorphisms in Surfactant Protein-D Are Associated with Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 44 (3) pp. 316-322. 10.1165/rcmb.2009-0360OC.

Fox, ZV; Cozzi-Lepri, A; Monforte, AD; Karlsson, A; Phillips, AN; Kronborg, G; Kjaer, J; ... EuroSIDA, ; + view all (2011) Predictors of having a resistance test following confirmed virological failure of combination antiretroviral therapy: data from EuroSIDA. ANTIVIR THER , 16 (5) 781 - 785. 10.3851/IMP1801.


Garcia, F; Alvarez, M; Fox, Z; Garcia-Diaz, A; Guillot, V; Johnson, M; Chueca, N; ... Geretti, AM; + view all (2011) Predicting antiretroviral drug resistance from the latest or the cumulative genotype. ANTIVIRAL THERAPY , 16 (3) pp. 373-381. 10.3851/IMP1753.

Goldhaber, SZ; Leizorovicz, A; Kakkar, AK; Haas, SK; Merli, G; Knabb, RM; Weitz, JI; (2011) Apixaban versus Enoxaparin for Thromboprophylaxis in Medically Ill Patients. NEW ENGLAND JOURNAL OF MEDICINE , 365 (23) pp. 2167-2177. 10.1056/NEJMoa1110899.

Gooding, K; Shore, A; von Lany, H; Ling, R; Mitra, M; Ball, C; Mawson, D; (2011) Are features of the metabolic syndrome associated with macular thickness in individuals without diabetes mellitus? In: JOURNAL OF VASCULAR RESEARCH. (pp. 273 - 273). KARGER

Gooptu, B; Chaban, Y; Irving, JA; Clare, DK; Lomas, DA; Orlova, E; Saibil, HR; (2011) 3D CRYO-ELECTRON MICROSCOPIC ANALYSIS OF THE DISEASE MECHANISM OF alpha 1-ANTITRYPSIN DEFICIENCY. In: (Proceedings) Winter Meeting of the British-Thoracic-Society. (pp. A115-A115). B M J PUBLISHING GROUP


Ham, C; Dixon, J; Chantler, C; (2011) Clinically integrated systems: the future of NHS reform in England? BRIT MED J , 342 , Article d905.

Hersh, CP; Silverman, EK; Gascon, J; Bhattacharya, S; Klanderman, BJ; Litonjua, AA; Lefebvre, V; ... Mariani, TJ; + view all (2011) SOX5 Is a Candidate Gene for Chronic Obstructive Pulmonary Disease Susceptibility and Is Necessary for Lung Development. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 183 (11) pp. 1482-1489. 10.1164/rccm.201010-1751OC.

Ho, DK; Chan, L; Hooper, A; Brennan, PE; (2011) A general and mild two-step procedure for the synthesis of aryl and heteroaryl sulfonamides from the corresponding iodides. Tetrahedron Letters , 52 (7) pp. 820-823. 10.1016/j.tetlet.2010.12.050.

Huang, XJ; Lodi, S; Fox, Z; Johnson, A; Porter, K; Xu, XN; Wu, H; (2011) Patterns of decrease in CD4 cell count after seroconversion: comparison between Beijing PRIMO cohort and CASCADE seroconverter cohorts. In: INT J INFECT DIS. (pp. S36 - S37). ELSEVIER SCI LTD


Irving, JA; Ekeowa, UI; Belorgey, D; Haq, I; Gooptu, B; Miranda, E; Perez, J; ... Lomas, DA; + view all (2011) THE SERPINOPATHIES: STUDYING SERPIN POLYMERIZATION IN VIVO. METHODS IN ENZYMOLOGY, VOL 501: SERPIN STRUCTURE AND EVOLUTION , 501 pp. 421-466. 10.1016/B978-0-12-385950-1.00018-3.


Jahn, TR; Kohlhoff, KJ; Scott, M; Tartaglia, GG; Lomas, DA; Dobson, CM; Vendruscolo, M; (2011) Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease. JOURNAL OF NEUROSCIENCE METHODS , 197 (1) pp. 186-189. 10.1016/j.jneumeth.2011.01.026.

Jensen, JU; Hein, L; Lundgren, B; Bestle, MH; Mohr, TT; Andersen, MH; Thornberg, KJ; ... Lundgren, JD; + view all (2011) Procalcitonin-guided interventions against infections to increase early appropriate antibiotics and improve survival in the intensive care unit: A randomized trial. CRITICAL CARE MEDICINE , 39 (9) pp. 2048-2058. 10.1097/CCM.0b013e31821e8791.


Kakkar, AK; Cimminiello, C; Goldhaber, SZ; Parakh, R; Wang, C; Bergmann, J-F; (2011) Low-Molecular-Weight Heparin and Mortality in Acutely Ill Medical Patients. NEW ENGLAND JOURNAL OF MEDICINE , 365 (26) pp. 2463-2472. 10.1056/NEJMoa1111288.

Kakkar, AK; Rushton-Smith, S; (2011) Venous Thromboembolism Pharmacologic Prophylaxis After Major Surgery-Are We Doing Well or Not Well Enough? ANNALS OF SURGERY , 253 (2) pp. 221-222. 10.1097/SLA.0b013e318208f427.

Kohlhoff, KJ; Jahn, TR; Lomas, DA; Dobson, CM; Crowther, DC; Vendruscolo, M; (2011) The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster. INTEGRATIVE BIOLOGY , 3 (7) pp. 755-760. 10.1039/c0ib00149j.

Kong, X; Cho, MH; Anderson, W; Coxson, HO; Muller, N; Washko, G; Hoffman, EA; ... Pillai, SG; + view all (2011) Genome-wide Association Study Identifies BICD1 as a Susceptibility Gene for Emphysema. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 183 (1) pp. 43-49. 10.1164/rccm.201004-0541OC.


Lipman, PJ; Cho, MH; Bakke, P; Gulsvik, A; Kong, X; Lomas, DA; Anderson, W; ... Lange, C; + view all (2011) On the Follow-Up of Genome-Wide Association Studies: An Overall Test for the Most Promising SNPs. GENETIC EPIDEMIOLOGY , 35 (5) pp. 303-309. 10.1002/gepi.20578.

Liu, B; Moloney, A; Meehan, S; Morris, K; Thomas, SE; Serpell, LC; Hider, R; ... Crowther, DC; + view all (2011) Iron Promotes the Toxicity of Amyloid beta Peptide by Impeding Its Ordered Aggregation. JOURNAL OF BIOLOGICAL CHEMISTRY , 286 (6) pp. 4248-4256. 10.1074/jbc.M110.158980.


McCreesh, N; Frost, S; Seeley, J; Katongole, J; Tarsh, MN; Ndungutse, R; Jichi, F; ... White, RG; + view all (2011) AN EMPIRICAL EVALUATION OF RESPONDENT-DRIVEN SAMPLING. In: (pp. A15-A16). B M J PUBLISHING GROUP

Mocroft, A; Lifson, AR; Touloumi, G; Neuhaus, J; Fox, Z; Palfreeman, A; Vjechas, MJ; ... INSIGHT Smart Study Grp, ; + view all (2011) Haemoglobin and anaemia in the SMART study. ANTIVIR THER , 16 (3) 329 - 337. 10.3851/IMP1746.

Morris, H; Morgan, MD; Wood, AM; Smith, SW; Ekeowa, UI; Herrmann, K; Holle, JU; ... Harper, L; + view all (2011) ANCA-associated vasculitis is linked to carriage of the Z allele of alpha(1) antitrypsin and its polymers. ANN RHEUM DIS , 70 (10) 1851 - 1856. 10.1136/ard.2011.153569.

Morris, H; Morgan, MD; Woods, A; Ekeowa, UI; Butherus, K; Holle, JU; Guillevin, L; ... Harper, L; + view all (2011) ANCA-AAV, polymers and carriage of the Z allele of alpha 1AT. In: (Proceedings) 15th International Vasculitis/ANCA Workshop. (pp. pp. 75-76). WILEY-BLACKWELL


Nyon, MP; Levy, G; Cabrita, L; Kirkpatrick, J; Roussell, B; Ekeowa, U; Patschull, A; ... Gooptu, B; + view all (2011) NMR Spectroscopy Reveals Structural Dynamics Of Alpha1-Antitrypsin In Health And Disease. In: AMER THORACIC SOC


Patil, S; Kaza, RCM; Kakkar, AK; Chamberlain, RS; (2011) Small cell carcinoma of the renal pelvis: a case report and review of the literature. ISRN Urol , 2011 786505-. 10.5402/2011/786505.

Patschull, AOM; Segu, L; Nyon, MP; Lomas, DA; Nobeli, I; Barrett, TE; Gooptu, B; (2011) Therapeutic target-site variability in α 1-antitrypsin characterized at high resolution. Acta Crystallographica Section F: Structural Biology and Crystallization Communications , 67 (12) pp. 1492-1497. 10.1107/S1744309111040267.


Qiu, W; Cho, MH; Riley, JH; Anderson, WH; Singh, D; Bakke, P; Gulsvik, A; ... ECLIPSE Investigators, ; + view all (2011) Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One , 6 (9) , Article e24395. 10.1371/journal.pone.0024395. Green open access


Rashid, ST; Yusa, K; Strick-Marchand, H; Lomas, DA; Bradly, A; Vallier, L; (2011) Human induced pluripotent stem cells for cell therapy against Inherited Metabolic disorders. HUMAN GENE THERAPY , 22 (10) A9-A10.

Rashid, ST; Yusa, K; Strick-Marchand, H; Rouhani, F; Miranda, E; Hannan, NR; Marciniak, SJ; ... Vallier, L; + view all (2011) TOWARDS CELL BASED THERAPY FOR alpha 1-ANTITRYPSIN DEFICIENCY THROUGH TARGETED BI-ALLELIC GENE CORRECTION IN HUMAN IPS CELLS. In: (Proceedings) 62nd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). (pp. 421A-421A). WILEY-BLACKWELL

Ribeiro, MMB; Pinto, A; Pinto, M; Heras, M; Martins, I; Correia, A; Bardaji, E; ... Castanho, M; + view all (2011) Inhibition of nociceptive responses after systemic administration of amidated kyotorphin. Br J Pharmacol , 163 (5) pp. 964-973. 10.1111/j.1476-5381.2011.01290.x.

Ribeiro, MMB; Pinto, ART; Domingues, MM; Serrano, I; Heras, M; Bardaji, ER; Tavares, I; (2011) Chemical conjugation of the neuropeptide kyotorphin and ibuprofen enhances brain targeting and analgesia. Mol Pharm , 8 (5) pp. 1929-1940. 10.1021/mp2003016.

Ribeiro, MMB; Serrano, ID; Santos, SS; (2011) Turning Endogenous Peptides into New Analgesics: The Example of Kyotorphin Derivatives. In: Peptide Drug Discovery and Development: Translational Research in Academia and Industry. (pp. 171-188).

Rodriguez-Gonzalez, R; Millan, M; Sobrino, T; Miranda, E; Brea, D; Perez de la Ossa, N; Blanco, M; ... Castillo, J; + view all (2011) The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome. THROMBOSIS AND HAEMOSTASIS , 105 (3) pp. 421-429. 10.1160/TH10-09-0621.

Rodriguez-Gonzalez, R; Sobrino, T; Rodriguez-Yanez, M; Millan, M; Brea, D; Miranda, E; Moldes, O; ... Castillo, J; + view all (2011) Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. JOURNAL OF TRANSLATIONAL MEDICINE , 9 (ARTN 58) 10.1186/1479-5876-9-58.

Roussel, BD; Irving, JA; Ekeowa, UI; Belorgey, D; Haq, I; Ordonez, A; Kruppa, AJ; ... Lomas, DA; + view all (2011) Unravelling the twists and turns of the serpinopathies. FEBS JOURNAL , 278 (20) pp. 3859-3867. 10.1111/j.1742-4658.2011.08201.x.


Schulman, S; Kakkar, AK; Schellong, SM; Goldhaber, SZ; Henry, E; Mismetti, P; Christiansen, AV; ... Kearon, C; + view all (2011) A Randomized Trial of Dabigatran Versus Warfarin in the Treatment of Acute Venous Thromboembolism (RE-COVER II). In: (Proceedings) 53rd Annual Meeting and Exposition of the American-Society-of-Hematology (ASH)/Symposium on the Basic Science of Hemostasis and Thrombosis. (pp. pp. 95-96). AMER SOC HEMATOLOGY

Screaton, NJ; Miller, FNAC; Patel, BD; Groves, A; Tasker, AD; Lomas, DA; Flower, CDR; (2011) The clinical impact of high resolution computed tomography in patients with respiratory disease. EUROPEAN RADIOLOGY , 21 (2) pp. 225-231. 10.1007/s00330-010-1923-3.

Siedlinski, M; Cho, MH; Bakke, P; Gulsvik, A; Lomas, DA; Anderson, W; Kong, X; ... Silverman, EK; + view all (2011) Genome-wide association study of smoking behaviours in patients with COPD. THORAX , 66 (10) pp. 894-902. 10.1136/thoraxjnl-2011-200154.

Silverman, EK; Vestbo, J; Agusti, A; Anderson, W; Bakke, PS; Barnes, KC; Barr, RG; ... Crapo, JD; + view all (2011) Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD , 8 (2) pp. 121-135. 10.3109/15412555.2011.558864.

Sin, DD; Miller, BE; Duvoix, A; Man, SFP; Zhang, X; Silverman, EK; Connett, JE; ... Lomas, DA; + view all (2011) Serum PARC/CCL-18 Concentrations and Health Outcomes in Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE , 183 (9) pp. 1187-1192. 10.1164/rccm.201008-1220OC.

Singh, A; Friden, V; Dasgupta, I; Foster, RR; Welsh, GI; Tooke, JE; Haraldsson, B; ... Satchell, SC; + view all (2011) High glucose causes dysfunction of the human glomerular endothelial glycocalyx. AM J PHYSIOL-RENAL , 300 (1) F40 - F48. 10.1152/ajprenal.00103.2010.

Spyropoulos, AC; Anderson, FA; FitzGerald, G; Decousus, H; Pini, M; Chong, BH; Zotz, RB; ... Spencer, FA; + view all (2011) Predictive and Associative Models to Identify Hospitalized Medical Patients at Risk for VTE. CHEST , 140 (3) pp. 706-714. 10.1378/chest.10-1944.


Turpie, AGG; Lassen, MR; Eriksson, BI; Gent, M; Berkowitz, SD; Misselwitz, F; Bandel, TJ; ... Kakkar, AK; + view all (2011) Rivaroxaban for the prevention of venous thromboembolism after hip or knee arthroplasty. THROMBOSIS AND HAEMOSTASIS , 105 (3) pp. 444-453. 10.1160/TH10-09-0601.


Vestbo, J; Edwards, LD; Scanlon, PD; Yates, JC; Agusti, A; Bakke, P; Calverley, PMA; ... Rennard, SI; + view all (2011) Changes in Forced Expiratory Volume in 1 Second over Time in COPD. NEW ENGLAND JOURNAL OF MEDICINE , 365 (13) pp. 1184-1192. 10.1056/NEJMoa1105482.

Vitiello, P; Garcia, A; Booth, C; Fox, Z; Owen, A; Johnson, J; Phillips, A; (2011) Drug levels and drug resistance after interruption of NNRTI-based HAART in the SMART trial. HIV MED , 12 4 - 5.


Wan, ES; Cho, MH; Boutaoui, N; Klanderman, BJ; Sylvia, JS; Ziniti, JP; Won, S; ... DeMeo, DL; + view all (2011) Genome-Wide Association Analysis of Body Mass in Chronic Obstructive Pulmonary Disease. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY , 45 (2) pp. 304-310. 10.1165/rcmb.2010-0294OC.

Whiteman, M; Strain, WD; Whatmore, JL; Gooding, K; Ball, C; Mawson, D; Tooke, JE; (2011) Sex differences in the association between plasma levels of the novel vasodilatory gas hydrogen sulfide, adiposity and micro- and macrovascular function in vivo. J HUM HYPERTENS , 25 (10) 651 - 651.

Woodcock, J; Franco, OH; Orsini, N; Roberts, I; (2011) Non-vigorous physical activity and all-cause mortality: systematic review and meta-analysis of cohort studies. Int J Epidemiol , 40 (1) pp. 121-138. 10.1093/ije/dyq104.


Yusa, K; Rashid, ST; Strick-Marchand, H; Varela, I; Liu, P-Q; Paschon, DE; Miranda, E; ... Vallier, L; + view all (2011) Targeted gene correction of alpha(1)-antitrypsin deficiency in induced pluripotent stem cells. NATURE , 478 (7369) 391-+. 10.1038/nature10424.

This list was generated on Sun Feb 18 04:56:52 2018 GMT.