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Number of items: 55.

C

Cellek, S; Foxwell, NA; Moncada, S; (2003) Two phases of nitrergic neuropathy in streptozotocin-induced diabetic rats. DIABETES , 52 (9) 2353 - 2362.

Cole, C; Reigan, P; Gbaj, A; Edwards, PN; Douglas, KT; Stratford, IJ; Freeman, S; (2003) Potential Tumor-Selective Nitroimidazolylmethyluracil Prodrug Derivatives: Inhibitors of the Angiogenic Enzyme Thymidine Phosphorylase. Journal of Medicinal Chemistry , 46 (2) pp. 207-209. 10.1021/jm020964w.

Cooke, L; Myers, L; Derakshan, N; (2003) Lung function, adherence and denial in asthma patients who exhibit a repressive coping style. Psychol Health Med , 8 (1) pp. 35-44. 10.1080/1354850021000059241.

Cowen, RL; Patterson, AV; Telfer, BA; Airley, RE; Hobbs, S; Phillips, RM; Jaffar, M; ... Williams, KJ; + view all (2003) Viral delivery of P450 reductase recapitulates the ability of constitutive overexpression of reductase enzymes to potentiate the activity of mitomycin C in human breast cancer xenografts. Molecular Cancer Therapeutics , 2 (9) pp. 901-909.

Crowther, DC; Serpell, LC; Dafforn, TR; Gooptu, B; Lomas, DA; (2003) Nucleation of alpha 1-antichymotrypsin polymerization. Biochemistry , 42 (8) pp. 2355-2363. 10.1021/bi0259305.

Cumming, S-A; Halsall, DJ; Ewan, PW; Lomas, DA; (2003) The effect of sequence variations within the coding region of the C1 inhibitor gene on disease expression and protein function in families with hereditary angio-oedema. J Med Genet , 40 (10) , Article e114.

D

Darwin, CR; Myers, LB; Ayers, S; Michie, S; (2003) British Psychological Society, Division of Health Psychology Annual Conference. Presented at: Exploring the information needs of patients with malignant melanoma at an outpatient clinic..

Decousus, H; Tapson, VF; Chong, BH; Merli, GJ; Kakkar, AK; FitzGerald, G; (2003) Immobility and advanced age: Critical factors contributing to the overall risk of venous thromboembolism in medical patients. In: (Proceedings) 45th Annual Meeting and Exhibition of the American-Society-of-Hematology. (pp. 56A-57A). AMER SOC HEMATOLOGY

Dragsted, UB; Gerstoft, J; Pedersen, C; Peters, B; Duran, A; Obel, N; Castagna, A; ... Lundgren, JD; + view all (2003) Randomized trial to evaluate indinavir/ritonavir versus saquinavir/ritonavir in human immunodeficiency virus type 1-infected patients: the MaxCmin1 Trial. The Journal of Infectious Diseases , 188 (5) pp. 635-642.

F

Fegan, PG; Tooke, JE; Gooding, KM; Tullett, JM; MacLeod, KM; Shore, AC; (2003) Capillary pressure in subjects with type 2 diabetes and hypertension and the effect of antihypertensive therapy. HYPERTENSION , 41 (5) 1111 - 1117. 10.1161/01.HYP.0000068200.09187.1E.

Freund, M; Kakkar, AK; Haas, S; Heilmann, L; von Tempelhoff, GF; Brom, J; Weidinger, G; (2003) A randomized trial of the low molecular weight heparin certoparin against placebo in the long-term prevention of venous thromboembolism in patients with metastatic breast cancer. In: (Proceedings) 45th Annual Meeting of the American-Society-of-Hematology. (pp. 210A-210A). AMER SOC HEMATOLOGY

G

Gaisser, S; Kellenberger, L; Kaja, AL; Weston, AJ; Lill, RE; Wirtz, G; Kendrew, SG; ... Leadlay, PF; + view all (2003) Direct production of ivermectin-like drugs after domain exchange in the avermectin polyketide synthase of Streptomyces avermitilis ATCC31272. Org Biomol Chem , 1 (16) pp. 2840-2847.

Goodyer, C; (2003) Synthesis of N-benzyl- and N-phenyl-2-amino-4,5-dihydrothiazoles and thioureas and evaluation as modulators of the isoforms of nitric oxide synthase. Bioorganic & Medicinal Chemistry , 11 (19) pp. 4189-4206. 10.1016/S0968-0896(03)00451-6.

Goodyer, CLM; Chinje, EC; Jaffar, M; Stratford, IJ; Threadgill, MD; (2003) Time-dependence and preliminary SAR studies in inhibition of nitric oxide synthase isoforms by homologues of thiocitrulline. Bioorganic & Medicinal Chemistry Letters , 13 (21) pp. 3679-3680. 10.1016/j.bmcl.2003.08.018.

Green, C; Brown, G; Dafforn, TR; Reichhart, J-M; Morley, T; Lomas, DA; Gubb, D; (2003) Drosophila necrotic mutations mirror disease-associated variants of human serpins. Development , 130 (7) pp. 1473-1478.

H

Holmes, A; Abraham, DJ; Chen, YJ; Denton, C; Xu, SW; Black, CM; Leask, A; (2003) Constitutive connective tissue growth factor expression in scleroderma fibroblasts is dependent on Sp1. J BIOL CHEM , 278 (43) 41728 - 41733. 10.1074/jbc.M305019200. Gold open access

J

Jaffar, M; Phillips, RM; Williams, KJ; Mrema, I; Cole, C; Wind, NS; Ward, TH; ... Patterson, AV; + view all (2003) 3-Substituted-5-aziridinyl-1-methylindole-4,7-diones as NQO1-directed antitumour agents: mechanism of activation and cytotoxicity in vitro. Biochemical Pharmacology , 66 (7) pp. 1199-1206. 10.1016/S0006-2952(03)00452-0.

K

Kakkar, AK; (2003) Antithrombotics and cancer: Evidence for survival benefit. PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS , 33 p. 67. 10.1159/000073299.

Kakkar, AK; (2003) Low-molecular-weight heparins: Beyond thrombosis in the management of the cancer patient. SEMINARS IN THROMBOSIS AND HEMOSTASIS , 29 pp. 13-15. 10.1055/s-2003-45412.

Kakkar, AK; (2003) An expanding role for antithrombotic therapy in cancer patients. CANCER TREATMENT REVIEWS , 29 pp. 23-26. 10.1016/S0305-7372(03)80006-3.

Kakkar, AK; Haas, S; Levine, M; (2003) Venous thromboembolism and its treatment in high-risk groups - Preface. SEMINARS IN THROMBOSIS AND HEMOSTASIS , 29 p. 1. 10.1055/s-2003-45417.

Kakkar, AK; Levine, M; Pinedo, HM; Wolff, R; Wong, J; (2003) Venous thrombosis in cancer patients: Insights from the FRONTLINE survey. ONCOLOGIST , 8 (4) pp. 381-388. 10.1634/theoncologist.8-4-381.

Kakkar, AK; Levine, MN; (2003) Management of thrombosis in patients with cancer: Can we do better? New evidence to shape future practice - Proceedings from a CME-accredited international symposium preceding the 44th Annual Meeting of the American Society of Hematology, 6 December 2002, in Philadelphia, Pennsylvania, USA. Introduction. CANCER TREATMENT REVIEWS , 29 p. 1. 10.1016/S0305-7372(03)80000-2.

Kerrison, S; McNally, N; Pollock, AM; (2003) United Kingdom research governance strategy. BRITISH MEDICAL JOURNAL , 327 (7414) pp. 553-556. 10.1136/bmj.327.7414.553.

Konopatskaya, O; Whatmore, JL; Tooke, JE; Shore, AC; (2003) Insulin and lysophosphatidylcholine synergistically stimulate NO-dependent cGMP production in human endothelial cells. DIABETIC MED , 20 (10) 838 - 845.

Kuenen, BC; Levi, M; Meijers, JCM; van Hinsbergh, VWM; Berkhof, J; Kakkar, AK; Hoekman, K; (2003) Potential role of platelets in endothelial damage observed during treatment with cisplatin, gemcitabine, and the angiogenesis inhibitor SU5416. JOURNAL OF CLINICAL ONCOLOGY , 21 (11) pp. 2192-2198. 10.1200/JCO.2003.08.046.

L

Leask, A; Holmes, A; Black, CM; Abraham, DJ; (2003) Connective tissue growth factor gene regulation - Requirements for its induction by transforming growth factor-beta 2 in fibroblasts. J BIOL CHEM , 278 (15) 13008 - 13015. 10.1074/jbc.M210366200. Gold open access

Leask, A; Holmes, AM; Pontocos, M; Rajkumar, V; Shiwen, X; Stratton, R; Abraham, D; (2003) Mechanism underlying the overexpression of CTGF in scleroderma fibroblasts: Role in elevated expression in scleroderma phenotype. In: (Proceedings) 67th Annual Scientific Meeting of the American-College-of-Rheumatology/38th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals. (pp. S155-S155). WILEY-LISS

Lee, AYY; Levine, MN; Baker, RI; Bowden, C; Kakkar, AK; Prins, M; Rickles, FR; ... Gent, M; + view all (2003) Low-molecular-weight heparin versus a coumarin for the prevention of recurrent venous thromboembolism in patients with cancer. NEW ENGLAND JOURNAL OF MEDICINE , 349 (2) pp. 146-153. 10.1056/NEJMoa025313.

Levine, MN; Lee, AY; Kakkar, AK; (2003) From Trousseau to targeted therapy: new insights and innovations in thrombosis and cancer. JOURNAL OF THROMBOSIS AND HAEMOSTASIS , 1 (7) pp. 1456-1463. 10.1046/j.1538-7836.2003.00275.x.

M

Marden, CM; Stefanidis, D; Cunninghame-Graham, DS; Casimir, CM; (2003) Differentiation-dependent up-regulation of p47(phox) gene transcription is associated with changes in PU.1 phosphorylation and increased binding affinity. Biochem Biophys Res Commun , 305 (1) pp. 193-202.

Martin, CJ; Timoney, MC; Sheridan, RM; Kendrew, SG; Wilkinson, B; Staunton, JC; Leadlay, PF; (2003) Heterologous expression in Saccharopolyspora erythraea of a pentaketide synthase derived from the spinosyn polyketide synthase. Org Biomol Chem , 1 (23) pp. 4144-4147. 10.1039/b310740j.

McNally, N; Kerrison, S; Pollock, AM; (2003) Reforming clinical research and development in England. BRITISH MEDICAL JOURNAL , 327 (7414) pp. 550-553. 10.1136/bmj.327.7414.550.

McNally, VA; Gbaj, A; Douglas, KT; Stratford, IJ; Jaffar, M; Freeman, S; Bryce, RA; (2003) Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening. Bioorganic & Medicinal Chemistry Letters , 13 (21) pp. 3705-3709. 10.1016/j.bmcl.2003.08.010.

Misra, P; Caldito, GC; Kakkar, AK; Mancini, MC; Reddy, PC; (2003) Outcomes of coronary artery bypass grafting in patients with a history of illicit drug use. AMERICAN JOURNAL OF CARDIOLOGY , 92 (5) pp. 593-595. 10.1016/S0002-9149(03)00730-6.

Monreal, M; Kakkar, AK; Caprini, JA; Barba, R; Uresandi, F; Valle, R; Suarez, C; (2003) Is the natural history of venous thromboembolism different in surgical and non-surgical-patients? Findings from the RIETE registry. In: (Proceedings) 45th Annual Meeting of the American-Society-of-Hematology. (pp. 112B-112B). AMER SOC HEMATOLOGY

Mukerjee, D; Yap, LB; Holmes, AM; Nair, D; Ayrton, P; Black, CM; Coghlan, JG; (2003) Significance of plasma N-terminal pro-brain natriuretic peptide in patients with systemic sclerosis-related pulmonary arterial hypertension. Respir Med , 97 (11) pp. 1230-1236.

Mulligan, K; Newman, S; (2003) Psychoeducational interventions in rheumatic diseases: A review of papers published from September 2001 to August 2002. CURRENT OPINION IN RHEUMATOLOGY , 15 (2) pp. 156-159. 10.1097/00002281-200303000-00013.

Mulligan, K; Newman, SP; (2003) Psycho-educational interventions in rheumatic disease: A review of papers published from September 2001 to August 2002. Current Opinion in Rheumatology , 15 pp. 156-159.

N

Nasir, FA; Patel, HK; Scully, MF; Fareed, J; Lemoine, NR; Kakkar, AK; (2003) The low molecular weight heparins dalteparin sodium inhibits angiogenesis and induces apoptosis in an experimental tumour model. In: (Proceedings) 45th Annual Meeting of the American-Society-of-Hematology. (pp. 808A-808A). AMER SOC HEMATOLOGY

O

O'Brien, P; Childs, AC; Ensor, GJ; Hill, CL; Kirby, JP; Dearden, MJ; Oxenford, SJ; (2003) cis- and trans-stereoselective epoxidation of N-protected 2-cyclohexen-1-ylamines. Org Lett , 5 (26) pp. 4955-4957. 10.1021/ol035873n.

P

Paisley, KE; Beaman, M; Tooke, JE; Mohamed-Ali, V; Lowe, GDO; Shore, AC; (2003) Endothelial dysfunction and inflammation in asymptomatic proteinuria. KIDNEY INT , 63 (2) 624 - 633.

Parfrey, H; Mahadeva, R; Lomas, DA; (2003) Alpha(1)-antitrypsin deficiency, liver disease and emphysema. Int J Biochem Cell Biol , 35 (7) pp. 1009-1014.

Parfrey, H; Mahadeva, R; Lomas, DA; (2003) alpha(l)-antitrypsin deficiency, liver disease and emphysema. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , 35 (7) pp. 1009-1014. 10.1016/S1357-2725(02)00250-9.

Parfrey, H; Mahadeva, R; Ravenhill, NA; Zhou, A; Dafforn, TR; Foreman, RC; Lomas, DA; (2003) Targeting a surface cavity of alpha 1-antitrypsin to prevent conformational disease. J Biol Chem , 278 (35) pp. 33060-33066. 10.1074/jbc.M302646200. Gold open access

Patel, BD; Jakes, RW; Welch, AA; Bingham, SA; Luber, RN; Day, NE; Khaw, KT; ... Wareham, NJ; + view all (2003) Are smokers with low plasma vitamin C levels at particular risk of COPD? In: (pp. p. 10).

Patel, BD; Loo, WJ; Tasker, AD; Screaton, NJ; Burrows, NI; Lomas, DA; (2003) COPD is associated with premature ageing of the skin. In: (pp. p. 74).

Patel, BD; Welch, AA; Bingham, SA; Luben, RN; Day, NE; Khaw, KT; Lomas, DA; (2003) Citrus fruit consumption is associated with a reduced risk of symptomatic asthma in adults. In: (pp. pp. 43-44).

Petkovic, H; Lill, RE; Sheridan, RM; Wilkinson, B; McCormick, EL; McArthur, HAI; Staunton, J; ... Kendrew, SG; + view all (2003) A novel erythromycin, 6-desmethyl erythromycin D, made by substituting an acyltransferase domain of the erythromycin polyketide synthase. J ANTIBIOT , 56 (6) 543 - 551.

Ponticos, M; Holmes, AM; Rajkumar, V; Wen, XS; Leask, A; Abraham, DJ; Black, CM; (2003) Connective tissue growth factor (CTGF) mediates extracellular matrix deposition in bleomycin-induced lung fibrosis via the MEK/ERK signaling pathways. In: ARTHRITIS AND RHEUMATISM. (pp. S156 - S156). WILEY-LISS

R

Robertson, AS; Belorgey, D; Lilley, KS; Lomas, DA; Gubb, D; Dafforn, TR; (2003) Characterization of the necrotic protein that regulates the Toll-mediated immune response in Drosophila. J Biol Chem , 278 (8) pp. 6175-6180. 10.1074/jbc.M209277200. Gold open access

S

Stratford, IJ; Williams, KJ; Cowen, RL; Jaffar, M; (2003) Combining bioreductive drugs and radiation for the treatment of solid tumors. Seminars in Radiation Oncology , 13 (1) pp. 42-52. 10.1053/srao.2003.50008.

Stygall, J; Newman, SP; Fitzgerald, G; Steed, L; Mulligan, K; Arrowsmith, JE; Pugsley, W; ... Harrison, MJ; + view all (2003) Cognitive change 5 years after coronary artery bypass surgery. HEALTH PSYCHOL , 22 (6) 579 - 586. 10.1037/0278-6133.22.6.579.

W

Wilkinson, B; Kendrew, SG; Sheridan, RM; Leadlay, PF; (2003) Biosynthetic engineering of polyketide synthases. EXPERT OPIN THER PAT , 13 (10) 1579 - 1606.

Z

Zacharoulis, D; Kakkar, AK; (2003) Venous thromboembolism in laparoscopic surgery. CURRENT OPINION IN PULMONARY MEDICINE , 9 (5) pp. 356-361. 10.1097/00063198-200309000-00003.

This list was generated on Sun Sep 17 04:43:32 2017 BST.