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Jump to: B | C | D | E | F | G | H | I | J | K | L | M | Q | R | S | V | W | Y
Number of items: 33.

B

Bafadhel, M and McKenna, S and Terry, S and Mistry, V and Reid, C and Haldar, P and McCormick, M and Haldar, K and Kebadze, T and Duvoix, A and Lindblad, K and Patel, H and Rugman, P and Dodson, P and Jenkins, M and Saunders, M and Newbold, P and Green, RH and Venge, P and Lomas, DA and Barer, MR and Johnston, SL and Pavord, ID and Brightling, CE (2011) Acute exacerbations of chronic obstructive pulmonary disease: identification of biologic clusters and their biomarkers. Am J Respir Crit Care Med , 184 (6) 662 - 671. 10.1164/rccm.201104-0597OC.

Bakke, PS and Zhu, G and Gulsvik, A and Kong, X and Agusti, AG and Calverley, PM and Donner, CF and Levy, RD and Make, BJ and Paré, PD and Rennard, SI and Vestbo, J and Wouters, EF and Anderson, W and Lomas, DA and Silverman, EK and Pillai, SG (2011) Candidate genes for COPD in two large data sets. Eur Respir J , 37 (2) 255 - 263. 10.1183/09031936.00091709.

Belorgey, D and Irving, JA and Ekeowa, UI and Freeke, J and Roussel, BD and Miranda, E and Pérez, J and Robinson, CV and Marciniak, SJ and Crowther, DC and Michel, CH and Lomas, DA (2011) Characterisation of serpin polymers in vitro and in vivo. Methods , 53 (3) 255 - 266. 10.1016/j.ymeth.2010.11.008.

Brehm, JM and Hagiwara, K and Tesfaigzi, Y and Bruse, S and Mariani, TJ and Bhattacharya, S and Boutaoui, N and Ziniti, JP and Soto-Quiros, ME and Avila, L and Cho, MH and Himes, B and Litonjua, AA and Jacobson, F and Bakke, P and Gulsvik, A and Anderson, WH and Lomas, DA and Forno, E and Datta, S and Silverman, EK and Celedón, JC (2011) Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease. Thorax , 66 (12) 1085 - 1090. 10.1136/thoraxjnl-2011-200017.

C

Castaldi, PJ and Cho, MH and Litonjua, AA and Bakke, P and Gulsvik, A and Lomas, DA and Anderson, W and Beaty, TH and Hokanson, JE and Crapo, JD and Laird, N and Silverman, EK and COPDGene and Eclipse Investigators, (2011) The association of genome-wide significant spirometric loci with chronic obstructive pulmonary disease susceptibility. Am J Respir Cell Mol Biol , 45 (6) 1147 - 1153. 10.1165/rcmb.2011-0055OC.

Castaldi, PJ and Demeo, DL and Hersh, CP and Lomas, DA and Soerheim, IC and Gulsvik, A and Bakke, P and Rennard, S and Pare, P and Vestbo, J and AATGM Investigators, and ICGN Investigators, and Silverman, EK (2011) Impact of non-linear smoking effects on the identification of gene-by-smoking interactions in COPD genetics studies. Thorax , 66 (10) 903 - 909. 10.1136/thx.2010.146118.

D

Dickens, JA and Lomas, DA (2011) Why has it been so difficult to prove the efficacy of alpha-1-antitrypsin replacement therapy? Insights from the study of disease pathogenesis. Drug Des Devel Ther , 5 391 - 405. 10.2147/DDDT.S14018.

Dickens, JA and Miller, BE and Edwards, LD and Silverman, EK and Lomas, DA and Tal-Singer, R and Evaluation of COPD Longitudinally to Identify Surrogate Endpoints (ECLIPSE) study investigators, (2011) COPD association and repeatability of blood biomarkers in the ECLIPSE cohort. Respir Res , 12 146 - ?. 10.1186/1465-9921-12-146.

Duvoix, A and Miranda, E and Perez, J and Sorensen, GL and Holmskov, U and Trapnell, BC and Madsen, J and Clark, HW and Edwards, LD and Miller, BE and Tal-Singer, RM and Lomas, DA (2011) Evaluation of full-length, cleaved and nitrosylated serum surfactant protein D as biomarkers for COPD. COPD , 8 (2) 79 - 95. 10.3109/15412555.2011.558542.

E

Ekeowa, UI and Marciniak, SJ and Lomas, DA (2011) α(1)-antitrypsin deficiency and inflammation. Expert Rev Clin Immunol , 7 (2) 243 - 252. 10.1586/eci.10.95.

F

Foreman, MG and Kong, X and DeMeo, DL and Pillai, SG and Hersh, CP and Bakke, P and Gulsvik, A and Lomas, DA and Litonjua, AA and Shapiro, SD and Tal-Singer, R and Silverman, EK (2011) Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol , 44 (3) 316 - 322. 10.1165/rcmb.2009-0360OC.

G

Gooptu, B and Chaban, Y and Irving, JA and Clare, DK and Lomas, DA and Orlova, E and Saibil, HR (2011) 3D CRYO-ELECTRON MICROSCOPIC ANALYSIS OF THE DISEASE MECHANISM OF alpha 1-ANTITRYPSIN DEFICIENCY. In: THORAX. (pp. A115 - A115).

H

Hersh, CP and Silverman, EK and Gascon, J and Bhattacharya, S and Klanderman, BJ and Litonjua, AA and Lefebvre, V and Sparrow, D and Reilly, JJ and Anderson, WH and Lomas, DA and Mariani, TJ (2011) SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development. Am J Respir Crit Care Med , 183 (11) 1482 - 1489. 10.1164/rccm.201010-1751OC.

I

Irving, JA and Ekeowa, UI and Belorgey, D and Haq, I and Gooptu, B and Miranda, E and Pérez, J and Roussel, BD and Ordóñez, A and Dalton, LE and Thomas, SE and Marciniak, SJ and Parfrey, H and Chilvers, ER and Teckman, JH and Alam, S and Mahadeva, R and Rashid, ST and Vallier, L and Lomas, DA (2011) The serpinopathies studying serpin polymerization in vivo. Methods Enzymol , 501 421 - 466. 10.1016/B978-0-12-385950-1.00018-3.

J

Jahn, TR and Kohlhoff, KJ and Scott, M and Tartaglia, GG and Lomas, DA and Dobson, CM and Vendruscolo, M and Crowther, DC (2011) Detection of early locomotor abnormalities in a Drosophila model of Alzheimer's disease. J Neurosci Methods , 197 (1) 186 - 189. 10.1016/j.jneumeth.2011.01.026.

K

Kohlhoff, KJ and Jahn, TR and Lomas, DA and Dobson, CM and Crowther, DC and Vendruscolo, M (2011) The iFly tracking system for an automated locomotor and behavioural analysis of Drosophila melanogaster. Integr Biol (Camb) , 3 (7) 755 - 760. 10.1039/c0ib00149j.

Kong, X and Cho, MH and Anderson, W and Coxson, HO and Muller, N and Washko, G and Hoffman, EA and Bakke, P and Gulsvik, A and Lomas, DA and Silverman, EK and Pillai, SG and ECLIPSE Study NETT Investigators, (2011) Genome-wide association study identifies BICD1 as a susceptibility gene for emphysema. Am J Respir Crit Care Med , 183 (1) 43 - 49. 10.1164/rccm.201004-0541OC.

L

Lipman, PJ and Cho, MH and Bakke, P and Gulsvik, A and Kong, X and Lomas, DA and Anderson, W and Silverman, EK and Lange, C (2011) On the follow-up of genome-wide association studies: an overall test for the most promising SNPs. Genet Epidemiol , 35 (5) 303 - 309. 10.1002/gepi.20578.

Liu, B and Moloney, A and Meehan, S and Morris, K and Thomas, SE and Serpell, LC and Hider, R and Marciniak, SJ and Lomas, DA and Crowther, DC (2011) Iron promotes the toxicity of amyloid beta peptide by impeding its ordered aggregation. J Biol Chem , 286 (6) 4248 - 4256. 10.1074/jbc.M110.158980.

M

Morris, H and Morgan, MD and Woods, A and Ekeowa, UI and Butherus, K and Holle, JU and Guillevin, L and Miranda, E and Lomas, DA and Perez, J and Pusey, C and Salama, A and Stockley, R and Wieczorek, S and Williams, J and Savage, CO and Harper, L (2011) ANCA-AAV, polymers and carriage of the Z allele of alpha 1AT. In: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. (pp. 75 - 76).

Q

Qiu, W and Cho, MH and Riley, JH and Anderson, WH and Singh, D and Bakke, P and Gulsvik, A and Litonjua, AA and Lomas, DA and Crapo, JD and Beaty, TH and Celli, BR and Rennard, S and Tal-Singer, R and Fox, SM and Silverman, EK and Hersh, CP and ECLIPSE Investigators, (2011) Genetics of sputum gene expression in chronic obstructive pulmonary disease. PLoS One , 6 (9) , Article e24395 . 10.1371/journal.pone.0024395.
An open access publication. A version is also available from UCL Discovery.
 file

R

Rashid, ST and Yusa, K and Strick-Marchand, H and Lomas, DA and Bradly, A and Vallier, L (2011) Human induced pluripotent stem cells for cell therapy against Inherited Metabolic disorders. HUMAN GENE THERAPY , 22 (10) A9 - A10.

Rashid, ST and Yusa, K and Strick-Marchand, H and Rouhani, F and Miranda, E and Hannan, NR and Marciniak, SJ and Alexander, GJ and Di Santo, J and Bradley, A and Lomas, DA and Vallier, L (2011) TOWARDS CELL BASED THERAPY FOR alpha 1-ANTITRYPSIN DEFICIENCY THROUGH TARGETED BI-ALLELIC GENE CORRECTION IN HUMAN IPS CELLS. In: HEPATOLOGY. (pp. 421A - 421A).

Rodríguez-González, R and Millán, M and Sobrino, T and Miranda, E and Brea, D and de la Ossa, NP and Blanco, M and Perez, J and Dorado, L and Castellanos, M and Lomas, DA and Moro, MA and Dávalos, A and Castillo, J (2011) The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome. Thromb Haemost , 105 (3) 421 - 429. 10.1160/TH10-09-0621.

Rodríguez-González, R and Sobrino, T and Rodríguez-Yáñez, M and Millán, M and Brea, D and Miranda, E and Moldes, O and Pérez, J and Lomas, DA and Leira, R and Dávalos, A and Castillo, J (2011) Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. J Transl Med , 9 58 - ?. 10.1186/1479-5876-9-58.

Roussel, BD and Irving, JA and Ekeowa, UI and Belorgey, D and Haq, I and Ordóñez, A and Kruppa, AJ and Duvoix, A and Rashid, ST and Crowther, DC and Marciniak, SJ and Lomas, DA (2011) Unravelling the twists and turns of the serpinopathies. FEBS J , 278 (20) 3859 - 3867. 10.1111/j.1742-4658.2011.08201.x.

S

Screaton, NJ and Miller, FN and Patel, BD and Groves, A and Tasker, AD and Lomas, DA and Flower, CD (2011) The clinical impact of high resolution computed tomography in patients with respiratory disease. Eur Radiol , 21 (2) 225 - 231. 10.1007/s00330-010-1923-3.

Siedlinski, M and Cho, MH and Bakke, P and Gulsvik, A and Lomas, DA and Anderson, W and Kong, X and Rennard, SI and Beaty, TH and Hokanson, JE and Crapo, JD and Silverman, EK and COPDGene Investigators, and ECLIPSE Investigators, (2011) Genome-wide association study of smoking behaviours in patients with COPD. Thorax , 66 (10) 894 - 902. 10.1136/thoraxjnl-2011-200154.

Silverman, EK and Vestbo, J and Agusti, A and Anderson, W and Bakke, PS and Barnes, KC and Barr, RG and Bleecker, ER and Boezen, HM and Burkart, KM and Celli, BR and Cho, MH and Cookson, WO and Croxton, T and Daley, D and DeMeo, DL and Gan, W and Garcia-Aymerich, J and Hall, IP and Hansel, NN and Hersh, CP and Kalsheker, N and Kiley, JP and Kim, WJ and Lambrechts, D and Lee, SD and Litonjua, AA and Lomas, DA and London, SJ and Nishimura, M and Nørdestgaard, BG and O'Donnell, CJ and Postma, DS and Puhan, MA and Tesfaigzi, Y and Tobin, MD and Vogelmeier, C and Wilk, JB and Wouters, E and Young, RP and Ziegler-Heitbrock, L and MacNee, W and Crapo, JD (2011) Opportunities and challenges in the genetics of COPD 2010: an International COPD Genetics Conference report. COPD , 8 (2) 121 - 135. 10.3109/15412555.2011.558864.

Sin, DD and Miller, BE and Duvoix, A and Man, SF and Zhang, X and Silverman, EK and Connett, JE and Anthonisen, NA and Wise, RA and Tashkin, D and Celli, BR and Edwards, LD and Locantore, N and Macnee, W and Tal-Singer, R and Lomas, DA and ECLIPSE Investigators, (2011) Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease. Am J Respir Crit Care Med , 183 (9) 1187 - 1192. 10.1164/rccm.201008-1220OC.

V

Vestbo, J and Edwards, LD and Scanlon, PD and Yates, JC and Agusti, A and Bakke, P and Calverley, PM and Celli, B and Coxson, HO and Crim, C and Lomas, DA and MacNee, W and Miller, BE and Silverman, EK and Tal-Singer, R and Wouters, E and Rennard, SI and ECLIPSE Investigators, (2011) Changes in forced expiratory volume in 1 second over time in COPD. N Engl J Med , 365 (13) 1184 - 1192. 10.1056/NEJMoa1105482.

W

Wan, ES and Cho, MH and Boutaoui, N and Klanderman, BJ and Sylvia, JS and Ziniti, JP and Won, S and Lange, C and Pillai, SG and Anderson, WH and Kong, X and Lomas, DA and Bakke, PS and Gulsvik, A and Regan, EA and Murphy, JR and Make, BJ and Crapo, JD and Wouters, EF and Celli, BR and Silverman, EK and DeMeo, DL and Evaluation of Chronic Obstructive Pulmonary Disease Longitudinally to Identify Predictive Surrogate End-Points (ECLIPSE), and Norway-Bergen cohort, and National Emphysema Treatment Trial, and COPD Gene investigators, (2011) Genome-wide association analysis of body mass in chronic obstructive pulmonary disease. Am J Respir Cell Mol Biol , 45 (2) 304 - 310. 10.1165/rcmb.2010-0294OC.

Y

Yusa, K and Rashid, ST and Strick-Marchand, H and Varela, I and Liu, PQ and Paschon, DE and Miranda, E and Ordóñez, A and Hannan, NR and Rouhani, FJ and Darche, S and Alexander, G and Marciniak, SJ and Fusaki, N and Hasegawa, M and Holmes, MC and Di Santo, JP and Lomas, DA and Bradley, A and Vallier, L (2011) Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells. Nature , 478 (7369) 391 - 394. 10.1038/nature10424.

This list was generated on Tue Jun 18 22:51:47 2013 BST.