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Number of items: 439.

A

Abdel-Gadir, A; Berber, R; Porter, JB; Quinn, PD; Suri, D; Kellman, P; Hart, AJ; ... Skinner, JA; + view all (2016) Detection of metallic cobalt and chromium liver deposition following failed hip replacement using T2* and R2 magnetic resonance. Journal of Cardiovascular Magnetic Resonance , 18 , Article 29. 10.1186/s12968-016-0248-z. Green open access
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Abdel-Gadir, A; Vorasettakarnkij, Y; Ngamkasem, H; Nordin, S; Ako, EA; Tumkosit, M; Sucharitchan, P; ... Moon, JC; + view all (2016) Ultrafast Magnetic Resonance Imaging for Iron Quantification in Thalassemia Participants in the Developing World The TIC-TOC Study (Thailand and UK International Collaboration in Thalassaemia Optimising Ultrafast CMR). Circulation , 134 (5) pp. 432-434. 10.1161/CIRCULATIONAHA.116.022803. Green open access
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Abdel-Gadir, A; Vorasettakarnkij, Y; Ngamkasem, H; Nordin, S; Ako, EO; Tumkosit, M; Sutcharitchan, P; ... Moon, J; + view all (2016) Ultrafast CMR to deliver high volume screening of an at risk thalassemia population in the developing world: preliminary results from the TIC-TOC study (Thailand and UK international collaboration in thalassaemia using an optimised ultrafast CMR protocol). Presented at: UNSPECIFIED.

Adams, RA; Brown, E; Brown, L; Butler, R; Falk, S; Fisher, D; Kaplan, R; ... Maughan, T; + view all (2016) FOCUS4-D: Results from a randomised, placebo controlled trial (RCT) of AZD8931 (an inhibitor of signalling by HER1, 2, and 3) in patients (pts) with advanced or metastatic colorectal cancer (aCRC) in tumours that are wildtype (wt) for BRAF, PIK3CA, KRAS & NRAS. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Ahmed, K; Kyte, D; Keeley, T; Efficace, F; Armes, J; Brown, JM; Calman, L; ... Calvert, M; + view all (2016) Systematic evaluation of patient-reported outcome (PRO) protocol content and reporting in UK cancer clinical trials: the EPiC study protocol. BMJ Open , 6 (9) , Article e012863. 10.1136/bmjopen-2016-012863. Green open access
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Ako, EOI; Barber, N; Kowalik, G; Steeden, JA; Porter, J; Walker, J; Muthurangu, V; (2016) MR-Augmented Cardiopulmonary Exercise Testing - a proof of concept in Sickle Cell Disease. Presented at: Society for Cardiovascular Magnetic Resonance: 19th Annual SCMR Scientific Sessions, Los Angeles, California, USA. Green open access
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Alliouachene, S; Bilanges, B; Chaussade, C; Pearce, W; Foukas, LC; Scudamore, CL; Moniz, LS; (2016) Inactivation of class II PI3K-C2α induces leptin resistance, age-dependent insulin resistance and obesity in male mice. Diabetologia , 59 (7) pp. 1503-1512. 10.1007/s00125-016-3963-y. Green open access
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Alrifai, D; ngan, S; shipway, D; (2016) Surgery for Upper Gastrointestinal Cancer in a Morbidly Obese Patient with Diabetes and Renal Impairment. In: Problem Solving in Older Cancer Patients A Case Study Based Reference and Learning Resource. Evidence-based Networks Ltd

Alzoubi, S; Brody, L; Rahman, S; Mahul-Mellier, AL; Mercado, N; Ito, K; El-Bahrawy, M; ... Hajji, N; + view all (2016) Synergy between histone deacetylase inhibitors and DNA-damaging agents is mediated by histone deacetylase 2 in colorectal cancer. Oncotarget , 7 (28) pp. 44505-44521. 10.18632/oncotarget.9887. Green open access
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Amelina, H; Moiseeva, V; Collopy, LC; Pearson, SR; Armstrong, CA; Tomita, K; (2016) Sequential and counter-selectable cassettes for fission yeast. BMC Biotechnology , 16 , Article 76. 10.1186/s12896-016-0307-4. Green open access
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Aneke, JC; Huntley, N; Porter, J; Eleftheriou, P; (2016) Effect of automated red cell exchanges on oxygen saturation on-air, blood parameters and length of hospitalization in sickle cell disease patients with acute chest syndrome. Nigerian Medical Journal , 57 (3) pp. 190-193. 10.4103/0300-1652.184073. Green open access
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Ang, JE; Pandher, R; Ang, JC; Asad, YJ; Henley, A; Valenti, M; Box, G; ... Raynaud, FI; + view all (2016) Plasma metabolomic changes following PI3K inhibition as pharmacodynamic biomarkers: preclinical discovery to Phase I trial evaluation. Molecular Cancer Therapeutics , 15 (6) pp. 1412-1424. 10.1158/1535-7163.MCT-15-0815. Green open access
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Angelopoulos, N; Abdallah, S; Giamas, G; (2016) Advances in integrative statistics for logic programming. International Journal of Approximate Reasoning , 78 pp. 103-115. 10.1016/j.ijar.2016.06.008. Green open access
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Anguita, E; Gupta, R; Olariu, V; Valk, PJ; Peterson, C; Delwel, R; Chaparro, A; ... Enver, T; + view all (2016) A SOMATIC MUTATION OF GFI1B IDENTIFIED IN LEUKEMIA ALTERS CELL FATE VIA A SPI1 (PU.1) CENTERED GENETIC REGULATORY NETWORK. Presented at: 21st Congress of the European-Hematology-Association, Copenhagen, DENMARK.

Anguita, E; Gupta, R; Olariu, V; Valk, PJ; Peterson, C; Delwel, R; Enver, T; (2016) A somatic mutation of GFI1B identified in leukemia alters cell fate via a SPI1 (PU.1) centered genetic regulatory network. Developmental Biology , 411 (2) pp. 277-286. 10.1016/j.ydbio.2016.02.002. Green open access
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Anjos-Afonso, F; Loizou, JI; Bradburn, A; Kanu, N; Purewal, S; Da Costa, C; Bonnet, D; (2016) Perturbed hematopoiesis in mice lacking ATMIN. Blood , 128 (16) pp. 2017-2021. 10.1182/blood-2015-09-672980. Green open access
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Anthias, CN; (2016) Related haematopoietic progenitor cell donor care: the influence of current guidance, and pathways to improvement. Doctoral thesis , UCL (University College London). Green open access
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Arachchillage, DRJ; Mackie, IJ; Efthymiou, M; Chitolie, A; Hunt, BJ; Isenberg, DA; Khamashta, M; ... Cohen, H; + view all (2016) Rivaroxaban limits complement activation compared with warfarin in antiphospholipid syndrome patients with venous thromboembolism. Journal of Thrombosis and Haemostasis , 14 (11) pp. 2177-2186. 10.1111/jth.13475. Green open access
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Aref, S; Bailey, K; Fielding, A; (2016) Measles to the Rescue: A Review of Oncolytic Measles Virus. Viruses , 8 (10) 10.3390/v8100294. Green open access
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Aref, S; Dey, A; Bailey, K; Rosen, B; Castleton, A; Szabadkai, G; Fielding, AK; (2016) Oncolytic Measles Virus Differentially Affects Mitochondrial Biogenesis in Transformed versus Non-Transformed BM-Derived MSCs. Presented at: 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), Washington, DC.

Arends, M; Wanner, C; Hughes, D; Mehta, A; Oder, D; Watkinson, OT; Elliott, PM; ... Hollak, CE; + view all (2016) Characterization of Classical and Nonclassical Fabry Disease: A Multicenter Study. Journal of the American Society of Nephrology , 28 (5) pp. 1631-1641. 10.1681/ASN.2016090964. Green open access
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Astle, WJ; Elding, H; Jiang, T; Allen, D; Ruklisa, D; Mann, AL; Mead, D; ... Soranzo, N; + view all (2016) The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease. Cell , 167 (5) pp. 1415-1429. 10.1016/j.cell.2016.10.042. Green open access
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Attard, G; Antonarakis, ES; (2016) Prostate cancer: AR aberrations and resistance to abiraterone or enzalutamide. Nature Reviews Urology , 13 (12) pp. 697-698. 10.1038/nrurol.2016.212. Green open access
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B

Bachanova, V; Weisdorf, DJ; Wang, T; Marsh, SG; Trachtenberg, E; Haagenson, MD; Spellman, SR; ... Cooley, SA; + view all (2016) Donor KIR B Genotype Improves Progression-Free Survival of Non-Hodgkin Lymphoma Patients Receiving Unrelated Donor Transplantation. Biology of Blood and Marrow Transplantation , 22 (9) pp. 1602-1607. 10.1016/j.bbmt.2016.05.016. Green open access
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Bailey, K; Dey, A; Aref, S; Broyer, L; Fielding, AK; (2016) Can Oncolytic Measles Virus Targeted to CD20 Recapitulate Any of the Effects of Rituximab in the Treatment of Acute Lymphoblastic Leukemia? Presented at: 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), Washington, DC.

Bangham, M; Goldstein, R; Walton, H; Ledermann, JA; (2016) Olaparib treatment for BRCA-mutant ovarian cancer with leptomeningeal disease. Gynecologic Oncology Reports , 18 pp. 22-24. 10.1016/j.gore.2016.10.004. Green open access
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Barnes, DJ; Hookway, E; Athanasou, N; Kashima, T; Oppermann, U; Hughes, S; Swan, D; ... Hassan, AB; + view all (2016) A germline mutation of CDKN2A and a novel RPLP1-C19MC fusion detected in a rare melanotic neuroectodermal tumor of infancy: a case report. BMC Cancer , 16 , Article 629. 10.1186/s12885-016-2669-3. Green open access
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Barrett, JE; Siriwardana, PN; Singh, S; Kim, P; Hochhauser, D; Davidson, BR; Ng, T; (2016) PROBING THE EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR) SIGNALLING PATHWAY IN COLORECTAL LIVER METASTASES (CRLM). Presented at: UNSPECIFIED.

Bartlett, TE; Chindera, K; McDermott, J; Breeze, CE; Cooke, WR; Jones, A; Reisel, D; ... Widschwendter, M; + view all (2016) Epigenetic reprogramming of fallopian tube fimbriae in BRCA mutation carriers defines early ovarian cancer evolution. Nature Communications , 7 , Article ARTN 116. 10.1038/ncomms11620. Green open access
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Beck, M; Hughes, D; Kampmann, C; Bizjajeva, S; Pintos-Morell, G; Ramaswami, U; West, M; (2016) Long-term outcomes with agalsidase alfa enzyme replacement therapy: Analysis using deconstructed composite events. Presented at: 12th Annual WORLD Symposium, San Diego, CA.

Beeken, RJ; Croker, H; Heinrich, M; Smith, L; Williams, K; Hackshaw, A; Hines, J; ... Fisher, A; + view all (2016) Study protocol for a randomised controlled trial of brief, habit-based, lifestyle advice for cancer survivors: exploring behavioural outcomes for the Advancing Survivorship Cancer Outcomes Trial (ASCOT). BMJ Open , 6 (11) , Article e011646. 10.1136/bmjopen-2016-011646. Green open access
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Behjati, S; Gundem, G; Wedge, DC; Roberts, ND; Tarpey, PS; Cooke, SL; Van Loo, P; ... Campbell, PJ; + view all (2016) Mutational signatures of ionizing radiation in second malignancies. Nature Communications , 7 , Article 12605. 10.1038/ncomms12605. Green open access
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Beltran, M; Yates, CM; Skalska, L; Dawson, M; Reis, FP; Viiri, K; Fisher, CL; ... Jenner, RG; + view all (2016) The interaction of PRC2 with RNA or chromatin is mutually antagonistic. Genome Research , 26 (7) pp. 896-907. 10.1101/gr.197632.115. Green open access
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Bendell, JC; Patel, MR; Yoshida, K; Seraj, J; Weaver, R; Lemech, C; Todaro, TG; ... Arkenau, H-T; + view all (2016) Phase 1 study of cardiac safety of TAS-102 in patients with advanced solid tumors. Cancer Chemother Pharmacol , 77 (6) pp. 1275-1283. 10.1007/s00280-016-3031-9. Green open access
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Benjamin, ER; Della Valle, C; Wu, X; Katz, E; Valenzano, KJ; Bichet, DG; Germain, D; ... Castelli, J; + view all (2016) The validation of pharmacogenetics in the identification of patients with Fabry disease for treatment with migalastat. Presented at: 12th Annual WORLD Symposium, San Diego, CA.

Benson, AB; Kiss, I; Bridgewater, J; Eskens, FALM; Sasse, C; Vossen, S; Chen, J; ... Krivoshik, A; + view all (2016) BATON-CRC: A Phase II Randomized Trial Comparing Tivozanib Plus mFOLFOX6 with Bevacizumab Plus mFOLFOX6 in Stage IV Metastatic Colorectal Cancer. Clinical Cancer Research , 22 (20) pp. 5058-5067. 10.1158/1078-0432.CCR-15-3117. Green open access
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Bentham, RB; (2016) A bioinfomatic analysis of the role of mitochondrial biogenesis in human pathologies. Doctoral thesis , UCL (University College London). Green open access
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Bentzen, AK; Marquard, AM; Lyngaa, R; Saini, SK; Ramskov, S; Donia, M; Such, L; ... Hadrup, SR; + view all (2016) Large-scale detection of antigen-specific T cells using peptide-MHC-I multimers labeled with DNA barcodes. Nature Biotechnology , 34 (10) pp. 1037-1045. 10.1038/nbt.3662. Green open access
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Bergerhoff, KF; (2016) Cellular and molecular events controlling acquisition of cytotoxic activity by melanoma-reactive CD4⁺ T cells in vivo. Doctoral thesis , UCL (University College London). Green open access
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Bettoun, A; Joffre, C; Zago, G; Surdez, D; Vallerand, D; Gundogdu, R; Sharif, AA; ... Hergovich, A; + view all (2016) Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation. Oncotarget , 7 (28) pp. 44142-44160. 10.18632/oncotarget.9875. Green open access
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Bhatnagar, G; Makanyanga, J; Ganeshan, B; Groves, A; Rodriguez-Justo, M; Halligan, S; Taylor, SA; (2016) MRI texture analysis parameters of contrast-enhanced T1-weighted images of Crohn's disease differ according to the presence or absence of histological markers of hypoxia and angiogenesis. Abdominal Radiology , 41 (7) pp. 1261-1269. 10.1007/s00261-016-0657-3. Green open access
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Biegstraaten, M; Cox, TM; Belmatoug, N; Berger, MG; Collin-Histed, T; Vom Dahl, S; Di Rocco, M; ... Hollak, CE; + view all (2016) Management goals for type 1 Gaucher disease: An expert consensus document from the European working group on Gaucher disease. Blood Cells, Molecules, and Diseases 10.1016/j.bcmd.2016.10.008. (In press). Green open access
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Blandford, A; Furniss, D; Lyons, I; Chumbley, G; Iacovides, I; Wei, L; Cox, A; ... Franklin, B; + view all (2016) Exploring the Current Landscape of Intravenous Infusion Practices and Errors (ECLIPSE): protocol for a mixed-methods observational study. BMJ Open , 6 , Article e009777. 10.1136/bmjopen-2015-009777. Green open access
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Bochtler, W; Gragert, L; Patel, ZI; Robinson, J; Steiner, D; Hofmann, JA; Pingel, J; ... Mueller, CR; + view all (2016) A comparative reference study for the validation of HLA-matching algorithms in the search for allogeneic hematopoietic stem cell donors and cord blood units. HLA , 87 (6) pp. 439-448. 10.1111/tan.12817. Green open access
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Bock, C; Halbritter, F; Carmona, FJ; Tierling, S; Datlinger, P; Assenov, Y; Berdasco, M; ... Zhang, K; + view all (2016) Quantitative comparison of DNA methylation assays for biomarker development and clinical applications. NATURE BIOTECHNOLOGY , 34 (7) pp. 726-737. 10.1038/nbt.3605. Green open access
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Bond, J; Domaschenz, R; Roman-Trufero, M; Sabbattini, P; Ferreiros-Vidal, I; Gerrard, G; Asnafi, V; ... Dillon, N; + view all (2016) Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia. Oncotarget , 7 (40) pp. 65923-65936. 10.18632/oncotarget.11688. Green open access
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Braso-Maristany, F; Filosto, S; Catchpole, S; Marlow, R; Quist, J; Francesch-Domenech, E; Plumb, DA; ... Tutt, AN; + view all (2016) PIM1 kinase regulates cell death, tumor growth and chemotherapy response in triple-negative breast cancer. Nature Medicine , 22 (11) pp. 1303-1313. 10.1038/nm.4198. Green open access
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Breeze, CE; Paul, DS; van Dongen, J; Butcher, LM; Ambrose, JC; Barrett, JE; Lowe, R; ... Beck, S; + view all (2016) eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data. Cell Reports , 17 (8) pp. 2137-2150. 10.1016/j.celrep.2016.10.059. Green open access
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Bridgewater, J; (2016) Adjuvant therapy for biliary tract cancer. Presented at: 3rd St. Gallen-International Gastrointestinal Cancer Conference on Primary Therapy of Early GI Cancer with International Treatment Consensus, St Gallen, SWITZERLAND.

Bridgewater, J; Lopes, A; Beare, S; Duggan, M; Lee, D; Ricamara, M; McEntee, D; ... Valle, JW; + view all (2016) A phase 1b study of Selumetinib in combination with Cisplatin and Gemcitabine in advanced or metastatic biliary tract cancer: the ABC-04 study. BMC Cancer , 16 (1) p. 153. 10.1186/s12885-016-2174-8. Green open access
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Brimble, MA; Zhou, J; Morton, C; Meagher, M; Nathwani, AC; Gray, JT; Davidoff, AM; (2016) AAV Preparations Contain Contamination from DNA Sequences in Production Plasmids Directly Outside of the ITRs. Presented at: 19th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), Washington DC, USA. Green open access
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Broushaki, F; Thomas, MG; Link, V; López, S; van Dorp, L; Kirsanow, K; Hofmanová, Z; ... Burger, J; + view all (2016) Early Neolithic genomes from the eastern Fertile Crescent. Science , 353 (6298) pp. 499-503. 10.1126/science.aaf7943. Green open access
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Brown, N; McBain, C; Nash, S; Hopkins, K; Sanghera, P; Saran, F; Phillips, M; ... Mulholland, P; + view all (2016) Multi-Center Randomized Phase II Study Comparing Cediranib plus Gefitinib with Cediranib plus Placebo in Subjects with Recurrent/Progressive Glioblastoma. PLoS ONE , 11 (5) 10.1371/journal.pone.0156369. Green open access
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Brown, S; Hinsley, S; Ballesteros, M; Bourne, S; McGarry, P; Sherratt, D; Flanagan, L; ... Myeloma UK Clinical Trials Network, .; + view all (2016) The MUK five protocol: a phase II randomised, controlled, parallel group, multi-centre trial of carfilzomib, cyclophosphamide and dexamethasone (CCD) vs. cyclophosphamide, bortezomib (Velcade) and dexamethasone (CVD) for first relapse and primary refractory multiple myeloma. BMC Hematology , 16 , Article 14. 10.1186/s12878-016-0053-9. Green open access
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Burrows, N; Cane, G; Robson, M; Gaude, E; J Howat, W; Szlosarek, PW; Pedley, RB; ... Maxwell, PH; + view all (2016) Hypoxia-induced nitric oxide production and tumour perfusion is inhibited by pegylated arginine deiminase (ADI-PEG20). Scientific Reports , 6 , Article 22950. 10.1038/srep22950. Green open access
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Butcher, LM; Ito, M; Brimpari, M; Morris, TJ; Soares, FA; Ährlund-Richter, L; Carey, N; ... Beck, S; + view all (2016) Non-CG DNA methylation is a biomarker for assessing endodermal differentiation capacity in pluripotent stem cells. Nature Communications , 7 , Article 10458. 10.1038/ncomms10458. Green open access
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Buzás, EI; Gardiner, C; Lee, C; Smith, ZJ; (2016) Single particle analysis: Methods for detection of platelet extracellular vesicles in suspension (excluding flow cytometry). Platelets , 28 (3) pp. 249-255. 10.1080/09537104.2016.1260704. Green open access
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C

Campbell, J; Ryan, CJ; Brough, R; Bajrami, I; Pemberton, HN; Chong, IY; Costa-Cabral, S; ... Lord, CJ; + view all (2016) Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines. Cell Reports , 14 (10) pp. 2490-2501. 10.1016/j.celrep.2016.02.023. Green open access
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Cappellini, MD; Cassiman, D; Marinakis, T; Rosenbaum, H; Bauduer, F; Bjerrum, OW; Fraga, C; ... Villarrubia, J; + view all (2016) Investigating rare haematological disorders - A celebration of 10 years of the Sherlock Holmes symposia. European Oncology and Haematology , 12 (1) pp. 55-61. 10.17925/EOH.2016.12.01.55. Green open access
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Carter, T; Brown, N; Shaw, H; Chester, K; Cohn-Brown, D; Mulholland, P; (2016) SURVIVAL AND EFFICACY DATA FOR PATIENTS WITH GLIOBLASTOMA TREATED WITH IPILIMUMAB IN COMBINATION WITH BEVACIZUMAB. Presented at: 21st Annual Scientific Meeting and Education Day of the Society-for-Neuro-Oncology, Scottsdale, AZ.

Carter, T; Mulholland, P; Chester, K; (2016) Antibody-targeted nanoparticles for cancer treatment. Immunotherapy , 8 (8) pp. 941-958. 10.2217/imt.16.11. Green open access
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Carter, T; Shawy, H; Cohn-Brown, D; Chester, K; Mulholland, P; (2016) Ipilimumab and Bevacizumab in Glioblastoma. Clinical Oncology , 28 (10) pp. 622-626. 10.1016/j.clon.2016.04.042. Green open access
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Castillo, SD; Tzouanacou, E; Zaw-Thin, M; Berenjeno, IM; Parker, VE; Chivite, I; Milà-Guasch, M; ... Vanhaesebroeck, B; + view all (2016) Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans. Science Translational Medicine , 8 (332) , Article 332ra43. 10.1126/scitranslmed.aad9982. Green open access
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Castillo, SD; Vanhaesebroeck, B; Sebire, NJ; (2016) Phosphoinositide 3-kinase: a new kid on the block in vascular anomalies. The Journal of Pathology , 240 (4) pp. 387-396. 10.1002/path.4802. Green open access
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Castillo-Quan, JI; Li, L; Kinghorn, KJ; Ivanov, DK; Tain, LS; Slack, C; Kerr, F; ... Partridge, L; + view all (2016) Lithium Promotes Longevity through GSK3/NRF2-Dependent Hormesis. Cell Reports , 15 (3) pp. 638-650. 10.1016/j.celrep.2016.03.041. Green open access
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Chaganti, S; Illidge, T; Barrington, S; Mckay, P; Linton, K; Cwynarski, K; McMillan, A; ... British Committee for Standards in Haematology, British Committee for Standards in Haematology; + view all (2016) Guidelines for the management of diffuse large B-cell lymphoma. Br J Haematol , 174 (1) pp. 43-56. 10.1111/bjh.14136. Green open access
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Chakravarthy, A; Henderson, S; Thirdborough, SM; Ottensmeier, CH; Su, X; Lechner, M; Feber, A; ... Fenton, TR; + view all (2016) Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx. Journal Of Clinical Oncology , 34 (34) pp. 4132-4141. 10.1200/JCO.2016.68.2955. Green open access
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Chen, L; Ge, B; Casale, FP; Vasquez, L; Kwan, T; Garrido-Martín, D; Watt, S; ... Soranzo, N; + view all (2016) Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells. Cell , 167 (5) 1398-1414.e24. 10.1016/j.cell.2016.10.026. Green open access
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Chen, X; Zhabyeyev, P; DesAulniers, J; Wang, X; Wang, F; Murray, AG; Kassiri, Z; ... Oudit, GY; + view all (2016) Distinctive Functions of PI3K beta in Endothelial Cells and Cardiomyocytes in Response to Myocardial Infarction: Complications for Targeting PI3K beta in Myocardial Infarction Treatment. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

Chen, Y; Breeze, CE; Zhen, S; Beck, S; Teschendorff, AE; (2016) Tissue-independent and tissue-specific patterns of DNA methylation alteration in cancer. Epigenetics & Chromatin , 9 , Article 10. 10.1186/s13072-016-0058-4. Green open access
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Chervova, O; Oksanen, L; (2016) Time reversal method with stabilizing boundary conditions for Photoacoustic tomography. Inverse Problems , 32 (12) , Article 125004. 10.1088/0266-5611/32/12/125004. Green open access
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Cheung, A; Bax, HJ; Josephs, DH; Ilieva, KM; Pellizzari, G; Opzoomer, J; Bloomfield, J; ... Karagiannis, SN; + view all (2016) Targeting folate receptor alpha for cancer treatment. Oncotarget , 7 (32) pp. 52553-52574. 10.18632/oncotarget.9651. Green open access
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Childs, A; Kirkwood, A; Edeline, J; Tu, VL; Watkins, J; Lamarca, A; Alrifai, D; ... Meyer, T; + view all (2016) Ki-67 index and response to chemotherapy in patients with neuroendocrine tumours. Endocrine-Related Cancer , 23 (7) pp. 563-570. 10.1530/ERC-16-0099. Green open access
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Childs, A; Vesely, C; Ensell, L; Lowe, H; Luong, TV; Caplin, ME; Toumpanakis, C; ... Meyer, T; + view all (2016) Expression of somatostatin receptors 2 and 5 in circulating tumour cells from patients with neuroendocrine tumours. British Journal of Cancer , 115 (12) pp. 1540-1547. 10.1038/bjc.2016.377. Green open access
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Childs, A; Vesely, C; Ensell, L; Luong, T; Caplin, M; Toumpanakis, C; Thirlwell, C; ... Meyer, T; + view all (2016) Detection of SSTR2 and 5 Expression on Circulating Tumour Cells in Neuroendocrine Tumours. Presented at: 13th Annual ENETS Conference for the Diagnosis and Treatment of Neuroendocrine Tumor Disease, Barcelona, SPAIN.

Chin, M; Sive, J; Allen, C; Roddie, C; Chavda, SJ; Smith, D; Popat, R; ... Yong, KL; + view all (2016) Prevalence of TP53 Mutations in Del(17p) Myeloma: Spectrum of Mutations and Effect on Survival. Presented at: 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA.

Chung, R; Maulik, A; Hamarneh, A; Hochhauser, D; Hausenloy, DJ; Walker, JM; Yellon, DM; (2016) Effect of Remote Ischaemic Conditioning in ONCology patients undergoing chemotherapy: rationale and design of the ERIC-ONC study - a single-center, blinded, randomized controlled trial. Clinical Cardiology , 39 (2) pp. 72-82. 10.1002/clc.22507. Green open access
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Ciré, S; Da Rocha, S; Ferrand, M; Collins, MK; Galy, A; (2016) In Vivo Gene Delivery to Lymph Node Stromal Cells Leads to Transgene-specific CD8+ T Cell Anergy in Mice. Molecular Therapy , 24 (11) pp. 1965-1973. 10.1038/mt.2016.168. Green open access
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Clayton, A; Lawson, C; Gardiner, C; Harrison, P; Carter, D; (2016) The 2nd United Kingdom Extracellular Vesicle Forum Meeting Abstracts: 15 December 2015, Hadyn Ellis Building, Cardiff University. Journal of Extracellular Vesicles , 5 , Article 30924. 10.3402/jev.v5.30924. Green open access
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Cohen, H; Hunt, BJ; Efthymiou, M; Arachchillage, DR; Mackie, IJ; Clawson, S; Sylvestre, Y; ... RAPS trial investigators, .; + view all (2016) Rivaroxaban versus warfarin to treat patients with thrombotic antiphospholipid syndrome, with or without systemic lupus erythematosus (RAPS): a randomised, controlled, open-label, phase 2/3, non-inferiority trial. Lancet Haematology , 3 (9) e426-e436. 10.1016/S2352-3026(16)30079-5. Green open access
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Cortés, E; Huidobro, PA; Sinclair, HG; Guldbrand, S; Peveler, WJ; Davies, T; Parrinello, S; ... Maier, SA; + view all (2016) Plasmonic Nanoprobes for Stimulated Emission Depletion Nanoscopy. ACS Nano , 10 (11) pp. 10454-10461. 10.1021/acsnano.6b06361. Green open access
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Coulter, TI; Chandra, A; Bacon, CM; Babar, J; Curtis, J; Screaton, N; Goodlad, JR; ... Cant, AJ; + view all (2016) Clinical spectrum and features of activated phosphoinositide 3-kinase δ syndrome: A large patient cohort study. J Allergy Clin Immunol 10.1016/j.jaci.2016.06.021. Green open access
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Cross, NCP; White, HE; Ernst, T; Welden, L; Dietz, C; Saglio, G; Mahon, F-X; ... Branford, S; + view all (2016) Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale. Leukemia , 30 (9) pp. 1844-1852. 10.1038/leu.2016.90. Green open access
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Crowley, C; Klanrit, P; Butler, CR; Varanou, A; Platé, M; Hynds, RE; Chambers, RC; ... Janes, SM; + view all (2016) Surface modification of a POSS-nanocomposite material to enhance cellular integration of a synthetic bioscaffold. Biomaterials , 83 pp. 283-293. 10.1016/j.biomaterials.2016.01.005. Green open access
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Culme-Seymour, EJ; Carvalho, C; Bain, O; Omakobia, E; Wilson, S; Knowles, H; Tebbs, S; ... Mason, C; + view all (2016) RegenVOX - Translational Exploitation Strategy for Stem Cell-Based Tissue-Engineered Laryngeal Implants Undergoing Phase I/II Clinical Trial. Presented at: 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), Washington, DC.

D

Dangoor, A; Seddon, B; Gerrand, C; Grimer, R; Whelan, J; Judson, I; (2016) UK guidelines for the management of soft tissue sarcomas. Clinical Sarcoma Research , 6 , Article 20. 10.1186/s13569-016-0060-4. Green open access
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Dilg, D; Saleh, R; Phelps, S; Rose, Y; Anderson, B; Scambler, P; Chapgier, ALA; (2016) HIRA is Required for Heart Development and Directly Regulates TNNI2 and TNNT3. Presented at: 10th Biennial International 22q11.2 Conference, Sirmione, Italy.

Dilg, D; Saleh, RNM; Phelps, SEL; Rose, Y; Dupays, L; Murphy, C; Mohun, T; ... Chapgier, ALA; + view all (2016) HIRA Is Required for Heart Development and Directly Regulates Tnni2 and Tnnt3. PLOS ONE , 11 (8) 10.1371/journal.pone.0161096. Green open access
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Dillon, M; Ellis, S; Grove, L; McLellan, L; Clack, G; Smith, S; Laude, J; ... Harrington, KJ; + view all (2016) PATRIOT: A phase I study to assess the tolerability, safety and biological effects of a specific ataxia telangiectasia and Rad3-related (ATR) inhibitor (AZD6738) as a single agent and in combination with palliative radiation therapy in patients with solid tumours. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Dirix, L; Swaisland, H; Verheul, HMW; Rottey, S; Leunen, K; Jerusalem, G; Rolfo, C; ... Plummer, R; + view all (2016) Effect of Itraconazole and Rifampin on the Pharmacokinetics of Olaparib in Patients With Advanced Solid Tumors: Results of Two Phase I Open-label Studies. Clinical Therapeutics , 38 (10) pp. 2286-2299. 10.1016/j.clinthera.2016.08.010. Green open access
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Domingo, E; Freeman-Mills, L; Rayner, E; Glaire, M; Briggs, S; Vermeulen, L; Fessler, E; ... Church, DN; + view all (2016) Somatic POLE proofreading domain mutation, immune response, and prognosis in colorectal cancer: a retrospective, pooled biomarker study. Lancet Gastroenterology and Hepatology , 1 (3) pp. 207-216. 10.1016/S2468-1253(16)30014-0. Green open access
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Domogala, A; Blundell, M; Laza-Briviesca, R; Thrasher, A; Lowdell, M; Madrigal, A; Saudemont, A; (2016) Unstimulated Natural Killer Cells Differentiated in Vitro from Umbilical Cord Blood CD34+ Cells Kill Patient AML Blasts in Vivo. Presented at: 42nd Annual Meeting of the European Society for Blood and Marrow Transplantation, Valencia, Spain.

Dondelinger, Y; Darding, M; Bertrand, MJ; Walczak, H; (2016) Poly-ubiquitination in TNFR1-mediated necroptosis. Cellular Molecular Life Sciences , 73 (11) pp. 2165-2176. 10.1007/s00018-016-2191-4. Green open access
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Downes, RJ; Vassiliev, D; (2016) Spectral theoretic characterization of the massless Dirac action. Mathematika , 62 pp. 701-718. 10.1112/S0025579315000509. Green open access
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Drummond, CJ; Esfandiari, A; Liu, J; Lu, X; Hutton, C; Jackson, J; Bennaceur, K; ... Lunec, J; + view all (2016) TP53 mutant MDM2-amplified cell lines selected for resistance to MDM2-p53 binding antagonists retain sensitivity to ionizing radiation. Oncotarget , 7 (29) pp. 46203-46218. 10.18632/oncotarget.10073. Green open access
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Dvorkina, M; Nieddu, V; Chakelam, S; Pezzolo, A; Cantilena, S; Leite, AP; Chayka, O; ... Salomoni, P; + view all (2016) A promyelocytic leukemia protein-thrombospondin 2 axis and the risk of relapse in neuroblastoma. Clinical Cancer Research , 22 (13) pp. 3398-3409. 10.1158/1078-0432.CCR-15-2081. Green open access
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de Boer, SM; Powell, ME; Mileshkin, L; Katsaros, D; Bessette, P; Haie-Meder, C; Ottevanger, PB; ... Creutzberg, CL; + view all (2016) Toxicity and quality of life after adjuvant chemoradiotherapy versus radiotherapy alone for women with high-risk endometrial cancer (PORTEC-3): an open-label, multicentre, randomised, phase 3 trial. Lancet Oncology , 17 (8) pp. 1114-1126. 10.1016/S1470-2045(16)30120-6. Green open access
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de Swart, L; Hendriks, J; van der Vorm, L; Cabantchik, I; Evans, P; Hod, E; Brittenham, G; ... Swinkels, D; + view all (2016) SECOND INTERNATIONAL ROUND ROBIN FOR THE QUANTIFICATION OF SERUM NON-TRANSFERRIN-BOUND IRON AND LABILE PLASMA IRON IN PATIENTS WITH IRON-OVERLOAD DISORDERS. Presented at: UNSPECIFIED.

E

Ebinger, S; Oezdemir, EZ; Ziegenhain, C; Tiedt, S; Alves, CC; Grunert, M; Dworzak, M; ... Jeremias, I; + view all (2016) Characterization of Rare, Dormant, and Therapy-Resistant Cells in Acute Lymphoblastic Leukemia. Cancer Cell , 30 (6) pp. 849-862. 10.1016/j.ccell.2016.11.002. Green open access
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Edeline, J; Blanc, JF; Johnson, P; Campillo-Gimenez, B; Ross, P; Ma, YT; King, J; ... Meyer, T; + view all (2016) A multicentre comparison between Child Pugh and Albumin-Bilirubin scores in patients treated with sorafenib for Hepatocellular Carcinoma. Liver International , 36 (12) pp. 1821-1828. 10.1111/liv.13170. Green open access
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Efthymiou, M; Arachchillage, D; Lane, PJ; Cohen, H; Mackie, I; (2016) Co-existence of Antibodies to Tissue Factor Pathway Inhibitor and Protein C May Provide a Marker for a Severe Thrombotic Phenotype. Presented at: 15th International Congress on Antiphospholipid Antibodies, North Cyprus.

Efthymiou, M; Mackie, I; Lane, PJ; Erkan, D; Cohen, H; (2016) Activated Protein C Resistance in Patients with Antiphospholipid Antibodies: Prevalence and Association with Protein C Antibodies. Presented at: 15th International Congress on Antiphospholipid Antibodies (ICAA 2016), North Cyprus.

Efthymiou, M; Mackie, I; Lane, PJ; Pengo, V; Andrade, D; Willis, R; Krilis, S; ... Cohen, H; + view all (2016) Antiphospholipid Syndrome Alliance for Clinical Trials and International Networking (APS ACTION) Clinical Database & Repository Analysis: The Comparison of Real World and Core Laboratory Lupus Anticoagulant Results. Presented at: 15th International Congress on Antiphospholipid Antibodies, North Cyprus.

El-Sharkawi, D; (2016) Studies to Investigate Epigenetic Factors in Acute Myeloid Leukaemia. Doctoral thesis , UCL (University College London). Green open access
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Engert, A; Balduini, C; Brand, A; Coiffier, B; Cordonnier, C; Doehner, H; de Wit, TD; ... Zieger, B; + view all (2016) The European Hematology Association Roadmap for European Hematology Research: a consensus document. Haematologica , 101 (2) pp. 115-208. 10.3324/haematol.2015.136739. Green open access
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Esfandiari, A; Hawthorne, TA; Nakjang, S; Lunec, J; (2016) Chemical Inhibition of Wild-Type p53-Induced Phosphatase 1 (WIP1/PPM1D) by GSK2830371 Potentiates the Sensitivity to MDM2 Inhibitors in a p53-Dependent Manner. Molecular Cancer Therapeutics , 15 (3) pp. 379-391. 10.1158/1535-7163.MCT-15-0651. Green open access
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Feber, A; Worth, DC; Chakravarthy, A; de Winter, P; Shah, K; Arya, M; Saqib, M; ... Kelly, JD; + view all (2016) CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma. Cancer Research , 76 (16) pp. 4720-4727. 10.1158/0008-5472.CAN-15-3134. Green open access
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Ferolla, P; Brizzi, MP; Meyer, T; Mansoor, W; Mazieres, J; Cao, CD; Lena, H; ... Baudin, E; + view all (2016) Efficacy and safety of pasireotide LAR or everolimus alone, or in combination in patients with advanced carcinoids (NET) of the lung/thymus: Results from the randomized, phase 2 LUNA study. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Fessler, E; Drost, J; van Hooff, SR; Linnekamp, JF; Wang, X; Jansen, M; De Sousa E Melo, F; ... Medema, JP; + view all (2016) TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype. EMBO Molecular Medicine , 8 (7) pp. 745-760. 10.15252/emmm.201606184. Green open access
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Findlay, JM; Castro-Giner, F; Makino, S; Rayner, E; Kartsonaki, C; Cross, W; Kovac, M; ... Tomlinson, I; + view all (2016) Differential clonal evolution in oesophageal cancers in response to neo-adjuvant chemotherapy. Nature Communications , 7 , Article 11111. 10.1038/ncomms11111. Green open access
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Flores-Borja, F; Irshad, S; Gordon, P; Wong, F; Sheriff, I; Tutt, A; Ng, T; (2016) Crosstalk between Innate Lymphoid Cells and Other Immune Cells in the Tumor Microenvironment. Journal of Immunology Research , Article 7803091. 10.1155/2016/7803091. Green open access
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Flynn, MJ; (2016) Mechanistic and pharmacodynamic studies of ADCT-301, an Antibody Drug Conjugate targeting CD25-expressing haematological malignancies. Doctoral thesis , UCL (University College London).

Flynn, MJ; Zammarchi, F; Tyrer, PC; Akarca, AU; Janghra, N; Britten, CE; Havenith, CEG; ... Hartley, JA; + view all (2016) ADCT-301, a Pyrrolobenzodiazepine (PBD) Dimer-Containing Antibody-Drug Conjugate (ADC) Targeting CD25-Expressing Hematological Malignancies. Molecular Cancer Therapeutics , 15 (11) pp. 2709-2721. 10.1158/1535-7163.MCT-16-0233. Green open access
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Forster, M; Mendes, R; Harrington, K; Guerrero-Urbano, T; Baines, H; Spanswick, V; Ensell, L; ... Beare, S; + view all (2016) A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck (HNSCC). Presented at: 2016 ASCO Annual Meeting, Chicago, IL, USA. Green open access
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Forster, MD; Mendes, R; Harrington, KJ; Urbano, TG; Baines, H; Spanswick, VJ; Ensell, L; ... Beare, S; + view all (2016) ORCA-2: A phase I study of olaparib in addition to cisplatin-based concurrent chemoradiotherapy for patients with high risk locally advanced squamous cell carcinoma of the head and neck. Presented at: Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), Chicago, IL.

Foulon, S; Brennan, B; Gaspar, N; Dirksen, U; Jeys, L; Cassoni, A; Claude, L; ... Le Deley, M-C; + view all (2016) Can postoperative radiotherapy be omitted in localised standard-risk Ewing sarcoma? An observational study of the Euro-E.W.I.N.G group. Eur J Cancer , 61 pp. 128-136. 10.1016/j.ejca.2016.03.075.

Foxall, E; Pipili, A; Jones, GE; Wells, CM; (2016) Significance of kinase activity in the dynamic invadosome. European Journal of Cell Biology , 95 (11) pp. 483-492. 10.1016/j.ejcb.2016.07.002. Green open access
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Francis, A; Stein, RC; Marshall, A; Rea, DW; Cameron, DA; Macpherson, IR; Earl, HM; ... Dunn, JA; + view all (2016) OPTIMA (Optimal Personalised Treatment of early breast cancer using Multi-parameter Analysis): A prospective trial to validate the predictive utility and cost-effectiveness of gene expression test-directed chemotherapy decisions. Presented at: UNSPECIFIED.

Franklin, JM; Sharma, RA; Harris, AL; Gleeson, FV; (2016) Imaging oligometastatic cancer before local treatment. The Lancet Oncology , 17 (9) e406-e414. 10.1016/S1470-2045(16)30277-7. Green open access
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Fujimitsu, K; Grimaldi, M; Yamano, H; (2016) Cyclin dependent kinase 1-dependent activation of APC/C ubiquitin ligase. Science , 352 (6289) pp. 1121-1124. 10.1126/science.aad3925. Green open access
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Furness, AJ; Quezada, SA; Peggs, KS; (2016) Neoantigen heterogeneity: a key driver of immune response and sensitivity to immune checkpoint blockade? [Editorial comment]. Immunotherapy , 8 (7) pp. 763-766. 10.2217/imt-2016-0064. Green open access
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Gaifulina, R; Maher, AT; Kendall, C; Nelson, J; Rodriguez-Justo, M; Lau, K; Thomas, GM; (2016) Label-free Raman spectroscopic imaging to extract morphological and chemical information from a formalin-fixed, paraffin-embedded rat colon tissue section. International Journal of Experimental Pathology , 97 (4) pp. 337-350. 10.1111/iep.12194. Green open access
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Gao, Y; Jones, A; Fasching, PA; Ruebner, M; Beckmann, MW; Widschwendter, M; Teschendorff, AE; (2016) The integrative epigenomic-transcriptomic landscape of ER positive breast cancer (vol 7, 126, 2015). Clinical Epigenetics , 8 , Article 63. 10.1186/s13148-016-0231-4. Green open access
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Garbowski, MW; Ma, Y; Fucharoen, S; Srichairatanakool, S; Hider, R; Porter, JB; (2016) Clinical and methodological factors affecting non-transferrin-bound iron values using a novel fluorescent bead assay. Translational Research , 177 19-30.e5. 10.1016/j.trsl.2016.05.005. Green open access
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Gardiner, C; Kiyoko, K; Patel, I; Lane, P; Machin, SJ; Mackie, I; (2016) A performance evaluation of a novel human recombinant tissue factor prothrombin time reagent. Presented at: UNSPECIFIED. Green open access
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Gardiner, C; Lane, P; Chitolie, A; Nunn, M; Kurono, H; Machin, S; Mackie, I; (2016) AUTOMATED ASSESSMENT OF THE COMPLEMENT SYSTEM. Presented at: UNSPECIFIED. Green open access
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Gardiner, C; Patel, I; Lane, P; Kiyoko, K; Machin, S; Mackie, I; (2016) A NOVEL PROTHROMBIN TIME REAGENT THAT UTILISES TISSUE FACTOR GENERATED BY SILK-WORM-BACULOVIRUS TECHNOLOGY. Presented at: UNSPECIFIED. Green open access
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Gardiner, C; Vizio, DD; Sahoo, S; Théry, C; Witwer, KW; Wauben, M; Hill, AF; (2016) Techniques used for the isolation and characterization of extracellular vesicles: results of a worldwide survey. Journal of Extracellular Vesicles , 5 , Article 32945. 10.3402/jev.v5.32945. Green open access
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Genadieva-Stavrik, S; Boumendil, A; Dreger, P; Peggs, K; Briones, J; Corradini, P; Bacigalupo, A; ... Sureda, A; + view all (2016) Myeloablative versus reduced intensity allogeneic stem cell transplantation for relapsed/refractory Hodgkin's lymphoma in recent years: a retrospective analysis of the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation. Annals of Oncology , 27 (12) pp. 2251-2257. 10.1093/annonc/mdw421. Green open access
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Germain, DP; Hughes, DA; Nicholls, K; Bichet, DG; Giugliani, R; Wilcox, WR; Feliciani, C; ... Schiffmann, R; + view all (2016) Treatment of Fabry’s Disease with the Pharmacologic Chaperone Migalastat. New England Journal of Medicine , 375 (6) pp. 545-555. 10.1056/NEJMoa1510198. Green open access
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Gillessen, S; Omlin, A; Attard, G; de Bono, JS; Efstathiou, E; Fizazi, K; Halabi, S; ... Tombal, B; + view all (2016) Management of patients with advanced prostate cancer: recommendations of the St Gallen Advanced Prostate Cancer Consensus Conference (APCCC) 2015. Annals of Oncology , 26 pp. 1589-1604. 10.1093/annonc/mdw180. Green open access
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Giugliani, R; Niu, DM; Ramaswami, U; West, M; Hughes, D; Kampmann, C; Pintos-Morell, G; ... Beck, M; + view all (2016) A 15-year perspective of the fabry outcome survey. Journal of Inborn Errors of Metabolism and Screening , 4 10.1177/2326409816666298. Green open access
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Gleeson, M; Hawkes, EA; Cunningham, D; Chadwick, N; Counsell, N; Lawrie, A; Jack, A; ... Linch, D; + view all (2016) Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisolone (R-CHOP) in the management of primary mediastinal B-cell lymphoma: a subgroup analysis of the UK NCRI R-CHOP 14 versus 21 trial. British Journal of Haematology , 175 (4) pp. 668-672. 10.1111/bjh.14287. Green open access
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Goekbuget, N; Dombret, H; Ribera, J-M; Fielding, AK; Advani, A; Bassan, R; Chia, V; ... Kantarjian, H; + view all (2016) International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia. Haematologica , 101 (12) pp. 1524-1533. 10.3324/haematol.2016.144311. Green open access
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Goel, A; Christudoss, P; George, R; Ramakrishna, B; Amirtharaj, GJ; Keshava, SN; Ramachandran, A; ... Eapen, CE; + view all (2016) Arsenicosis, possibly from contaminated groundwater, associated with noncirrhotic intrahepatic portal hypertension. Indian J Gastroenterol , 35 (3) pp. 207-215. 10.1007/s12664-016-0660-1. Green open access
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Goh, G; Schmid, R; Guiver, K; Arpornwirat, W; Chitapanarux, I; Ganju, V; Im, SA; ... Swanton, C; + view all (2016) Clonal Evolutionary Analysis during HER2 Blockade in HER2-Positive Inflammatory Breast Cancer: A Phase II Open-Label Clinical Trial of Afatinib +/- Vinorelbine. PLOS Med , 13 (12) , Article e1002136. 10.1371/journal.pmed.1002136. Green open access
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Goncalves, MR; (2016) Characterisation of cycling tumour hypoxia with magnetic resonance imaging. Doctoral thesis , UCL (University College London). Green open access
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Goswami, P; Salek, S; Fielding, A; Kell, J; Else, R; Keynes, M; Olivia, EN; (2016) Health-related quality of life issues in patients with haematological malignancy: a qualitative study. Presented at: UNSPECIFIED.

Griffiths, PD; Rothwell, E; Raza, M; Wilmore, S; Doyle, T; Harber, M; O'Beirne, J; ... Emery, VC; + view all (2016) Randomized Controlled Trials to Define Viral Load Thresholds for Cytomegalovirus Pre-Emptive Therapy. PLoS One , 11 (9) , Article e0163722. 10.1371/journal.pone.0163722. Green open access
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Grunewald, T; Ledermann, JA; (2016) Targeted Therapies for Ovarian Cancer. Best Practice & Research Clinical Obstetrics & Gynaecology 10.1016/j.bpobgyn.2016.12.001. (In press). Green open access
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Gu, Z; Churchman, M; Roberts, K; Li, Y; Liu, Y; Harvey, RC; McCastlain, K; ... Mullighan, CG; + view all (2016) Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia. Nature Communications , 7 , Article 13331. 10.1038/ncomms13331. Green open access
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Guibentif, C; Ronn, R; Lang, S; Boiers, C; Saxena, S; Soneji, S; Enver, T; ... Woods, N-B; + view all (2016) FUNCTIONAL AND MOLECULAR CHARACTERIZATION OF THE HUMAN ENDOTHELIAL-TO-HEMATOPOIETIC TRANSITION. Presented at: 45th Annual Scientific Meeting of the International-Society-for-Experimental-Hematology (ISEH), San Diego, CA.

Gulsen, T; Hadjicosti, I; Li, Y; Zhang, X; Whitley, PR; Chalmers, AD; (2016) Truncated RASSF7 promotes centrosomal defects and cell death. Developmental Biology , 409 (2) pp. 502-517. 10.1016/j.ydbio.2015.11.001. Green open access
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Gunnell, A; Webb, HM; Wood, CD; McClellan, MJ; Wichaidit, B; Kempkes, B; Jenner, RG; ... West, MJ; + view all (2016) RUNX super-enhancer control through the Notch pathway by Epstein-Barr virus transcription factors regulates B cell growth. Nucleic Acids Research , 44 (10) , Article 4636-4650. 10.1093/nar/gkw085. Green open access
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Gutteridge, A; Rathbone, VM; Gibbons, R; Amary, F; Archard, N; Davies, K; Brown, J; ... Forshew, T; + view all (2016) Digital PCR Analysis of Circulating Tumour DNA in a Broad Cohort of Sarcoma Patients. Presented at: 9th Joint Meeting of the British-Division of the International-Academy-of-Pathology and the Pathological-Society-of-Great-Britain-and-Ireland, Univ Nottingham, Sch Med, Acad Univ Mol Pathol Div Canc & Stem Cells, Nottingham, ENGLAND.

Gökbuget, N; Kelsh, M; Chia, V; Advani, A; Bassan, R; Dombret, H; Doubek, M; ... Kantarjian, H; + view all (2016) Blinatumomab vs historical standard therapy of adult relapsed/refractory acute lymphoblastic leukemia. Blood Cancer J , 6 (9) , Article e473. 10.1038/bcj.2016.84. Green open access
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Hachani, R; Lowdell, M; Birchall, M; Hervault, A; Mertz, D; Begin-Colin, S; Thanh, NT; (2016) Polyol synthesis, functionalisation, and biocompatibility studies of superparamagnetic iron oxide nanoparticles as potential MRI contrast agents. Nanoscale , 8 (6) pp. 3278-3287. 10.1039/c5nr03867g. Green open access
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Hall, AR; Burke, N; Dongworth, RK; Kalkhoran, SB; Dyson, A; Vicencio, JM; Dorn Ii, GW; ... Hausenloy, DJ; + view all (2016) Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction. Cell Death and Disease , 7 , Article e2238. 10.1038/cddis.2016.139. Green open access
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Halligan, S; Boone, D; Bhatnagar, G; Ahmad, T; Bloom, S; Rodriguez-Justo, M; Taylor, SA; (2016) Prognostic biomarkers to identify patients destined to develop severe Crohn's disease who may benefit from early biological therapy: protocol for a systematic review, meta-analysis and external validation. Syst Rev , 5 , Article 206. 10.1186/s13643-016-0383-5. Green open access
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Harrington, K; Forster, M; Dillon, M; Grove, L; Adeleke, S; Chen, S; Diamond, J; ... Greenberg, J; + view all (2016) Patritumab or Placebo Plus Cetuximab and Platinum-Based Therapy in Squamous Cell Carcinoma of the Head and Neck (SCCHN): a Phase 2 Study. Presented at: ASCO 2016 Annual Meeting: Poster Session, Head and Neck Cancer, Chicago. Green open access
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He, S; Mansour, MR; Zimmerman, MW; Ki, DH; Layden, HM; Akahane, K; Gjini, E; ... Look, AT; + view all (2016) Synergy between loss of NF1 and overexpression of MYCN in neuroblastoma is mediated by the GAP-related domain. eLife , 5 , Article e14. 10.7554/eLife.14713. Green open access
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Heinrich, M; Fisher, A; Paton, B; McCourt, O; Beeken, RJ; Hackshaw, A; Wardle, J; (2016) Lifestyle in Multiple Myeloma - a longitudinal cohort study protocol. BMC Cancer , 16 , Article 387. 10.1186/s12885-016-2407-x. Green open access
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Hendriksz, CJ; Berger, KI; Parini, R; AlSayed, MD; Raiman, J; Giugliani, R; Mitchell, JJ; ... Harmatz, PR; + view all (2016) Impact of long-term elosulfase alfa treatment on respiratory function in patients with Morquio A syndrome. Journal of Inherited Metabolic Disease , 39 (6) pp. 839-847. 10.1007/s10545-016-9973-6. Green open access
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Hendriksz, CJ; Parini, R; AlSayed, MD; Raiman, J; Giugliani, R; Solano Villarreal, ML; Mitchell, JJ; ... Harmatz, PR; + view all (2016) Long-term endurance and safety of elosulfase alfa enzyme replacement therapy in patients with Morquio A syndrome. Molecular Genetics and Metabolism , 119 (1-2) pp. 131-143. 10.1016/j.ymgme.2016.05.018. Green open access
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Henry, JY; Arce, F; Becher, B; Peggs, KS; Quezada, SA; (2016) Innate crosstalk between ILC and interstitial macrophages promotes lung cancer regression in response to IL-12 therapy. Presented at: UNSPECIFIED.

Henson, KE; Reulen, RC; Winter, DL; Bright, CJ; Fidler, MM; Frobisher, C; Guha, J; ... Hawkins, MM; + view all (2016) Cardiac Mortality Among 200 000 Five-Year Survivors of Cancer Diagnosed at 15 to 39 Years of Age: The Teenage and Young Adult Cancer Survivor Study. Circulation , 134 (20) pp. 1519-1531. 10.1161/CIRCULATIONAHA.116.022514. Green open access
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Hergovich, A; (2016) The Possible Crosstalk of MOB2 With NDR1/2 Kinases in Cell Cycle and DNA Damage Signaling. Journal of Cell Signaling , 1 (3) , Article 1000125. Green open access
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Herrero, J; Muffato, M; Beal, K; Fitzgerald, S; Gordon, L; Pignatelli, M; Vilella, AJ; ... Flicek, P; + view all (2016) Database: The Journal of Biological Databases and Curation. Database (Oxford) , 2016 pp. 1-17. 10.1093/database/bav096. Green open access
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Hertweck, A; Evans, CM; Eskandarpour, M; Lau, JC; Oleinika, K; Jackson, I; Kelly, A; ... Jenner, RG; + view all (2016) T-bet Activates Th1 Genes through Mediator and the Super Elongation Complex. Cell Reports , 15 (12) pp. 2756-2770. 10.1016/j.celrep.2016.05.054. Green open access
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Hiley, CT; Le Quesne, J; Santis, G; Sharpe, R; De Castro, DG; Middleton, G; Swanton, C; (2016) Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease. The Lancet , 388 (10048) pp. 1002-1011. 10.1016/S0140-6736(16)31340-X. Green open access
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Hirst, Y; Kerrison, R; Kobayashi, LC; Counsell, N; Djedovic, N; Ruwende, J; Stewart, M; (2016) Text Reminders in Colorectal Cancer Screening (TRICCS): Protocol for a randomised controlled trial. BMC Public Health 10.1186/s12889-016-2733-6. Green open access
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Hofmanová, Z; Kreutzer, S; Hellenthal, G; Sell, C; Diekmann, Y; Díez-Del-Molino, D; van Dorp, L; ... Burger, J; + view all (2016) Early farmers from across Europe directly descended from Neolithic Aegeans. Proceedings of the National Academy of Sciences of the United States of America , 113 (25) pp. 6886-6891. 10.1073/pnas.1523951113. Green open access
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Holler, A; Zech, M; Ghorashian, S; Pike, R; Hotblack, A; Velica, P; Xue, S-A; ... Stauss, HJ; + view all (2016) Expression of a dominant T-cell receptor can reduce toxicity and enhance tumor protection of allogeneic T-cell therapy. Haematologica , 101 (4) pp. 482-490. 10.3324/haematol.2015.132712. Green open access
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Hopper, C; Jerjes, W; Sultan, A; Forster, M; carnell, D; Simeon, C; Berg, K; ... Hamdoon, Z; + view all (2016) Disulfonated tetraphenyl chlorin (TPCS2a)–induced photochemical internalisation of bleomycin in patients with solid malignancies: A first-in-man phase I dose escalation clinical trial. The Lancet Oncology , 17 (9) pp. 1217-1229. 10.1016/S1470-2045(16)30224-8. Green open access
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Hotblack, A; Seshadri, S; Zhang, L; Hamrang-Yousefi, S; Chakraverty, R; Escors, D; Bennett, CL; (2016) Dendritic Cells Cross-Present Immunogenic Lentivector-Encoded Antigen from Transduced Cells to Prime Functional T Cell Immunity. Molecular Therapy , 25 (2) pp. 504-511. 10.1016/j.ymthe.2016.11.001. Green open access
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Huggett, MT; Tudzarova, S; Proctor, I; Loddo, M; Keane, MG; Stoeber, K; Williams, GH; (2016) Cdc7 is a potent anti-cancer target in pancreatic cancer due to abrogation of the DNA origin activation checkpoint. Oncotarget , 7 (14) pp. 18495-18507. 10.18632/oncotarget.7611. Green open access
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Hughes, A; Landers, D; Arkenau, H-T; Shah, S; Stephens, R; Mahal, A; Simmons, M; ... Royle, J; + view all (2016) Development and Evaluation of a New Technological Way of Engaging Patients and Enhancing Understanding of Drug Tolerability in Early Clinical Development: PROACT. Advances in Therapy , 33 (6) pp. 1012-1024. 10.1007/s12325-016-0335-4. Green open access
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Hughes, D; Bichet, DG; Germain, DP; Giugliani, R; Schiffmann, R; Wilcox, W; Castelli, JP; ... Barth, J; + view all (2016) Phenotype of Fabry disease in patients with mutations amenable to migalastat. Presented at: 12th Annual WORLD Symposium, San Diego, CA.

Hughes, DA; (2016) Fabry disease: will markers of early disease enable early treatment and better outcomes? Current Opinion in Cardiology , 31 (4) pp. 434-439. 10.1097/HCO.0000000000000308. Green open access
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Hurt, C; Bridgewater, J; Falk, S; Cummins, S; Wasan, H; Crosby, T; Radhakrishna, G; ... Mukherjee, S; + view all (2016) Long-term outcome from the SCALOP trial: a multi-centre randomized phase II trial of gemcitabine or capecitabine-based chemoradiation (CRT) for locally advanced pancreatic cancer (LAPC). Presented at: 18th World Congress of the European-Society-for-Medical-Oncology (ESMO) on Gastrointestinal Cancer, Barcelona, SPAIN.

Hussein, B; Maarouf, A; Gomez, K; Davies, J; Obeng-Tuudah, D; Riddell, A; Kadir, R; (2016) CHANGES IN PLATELET AGGREGATION DURING PREGNANCY AND THE IMMEDIATE POSTPARTUM PERIOD. Presented at: 21st Congress of the European-Hematology-Association, Copenhagen, DENMARK.

Hussein, B; Maarouf, A; Gomez, K; Davies, J; Riddell, A; Obeng-Tuudah, D; Kadir, R; (2016) CHANGES IN PLATELET AGGREGATION DURING PREGNANCY AND THE IMMEDIATE POSTPARTUM PERIOD. Presented at: European-Hematology-Association (EHA) Scientific Conference on Bleeding Disorders, Barcelona, SPAIN.

Hynds, RE; (2016) Characterisation of cultured airway basal cells to understand their role in human lung disease. Doctoral thesis , UCL (University College London). Green open access
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Hynds, RE; Butler, CR; Janes, SM; Giangreco, A; (2016) Expansion of Human Airway Basal Stem Cells and Their Differentiation as 3D Tracheospheres. Methods in Molecular Biology pp. 1-11. 10.1007/7651_2016_5. (In press). Green open access
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Hájek, R; Masszi, T; Petrucci, MT; Palumbo, A; Rosiñol, L; Nagler, A; Yong, KL; ... Ludwig, H; + view all (2016) A randomized phase III study of carfilzomib vs low-dose corticosteroids with optional cyclophosphamide in relapsed and refractory multiple myeloma (FOCUS). Leukemia , 31 (1) pp. 107-114. 10.1038/leu.2016.176. Green open access
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Inagaki, Y; Hookway, E; Williams, KA; Hassan, AB; Oppermann, U; Tanaka, Y; Soilleux, E; (2016) Dendritic and mast cell involvement in the inflammatory response to primary malignant bone tumours. Clinical Sarcoma Research , 6 , Article 13. 10.1186/s13569-016-0053-3. Green open access
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Ip, LRH; (2016) Effect of INPP4B loss on DNA repair and treatment strategies in ovarian cancer. Doctoral thesis , UCL (University College London). Green open access
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Isabelle, M; Dorney, J; Lewis, A; Lloyd, GR; Old, O; Shepherd, N; Rodriguez-Justo, M; ... Kendall, C; + view all (2016) Multi-centre Raman spectral mapping of oesophageal cancer tissues: a study to assess system transferability. Faraday Discussions , 187 pp. 87-103. 10.1039/c5fd00183h. Green open access
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Ivey, A; Hills, RK; Simpson, MA; Jovanovic, JV; Gilkes, A; Grech, A; Patel, Y; ... Grimwade, D; + view all (2016) Assessment of Minimal Residual Disease in Standard-Risk AML. The New England Journal Medicine , 374 (5) pp. 422-433. 10.1056/NEJMoa1507471. Green open access
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Jacobs, JG; Johnston, E; Freeman, A; Patel, D; Rodriguez-Justo, M; Atkinson, D; Punwani, S; ... Panagiotaki, E; + view all (2016) Histological validation of VERDICT cellularity map in a prostatectomy case. Presented at: International Society for Magnetic Resonance in Medicine 24th Annual Meeting, Singapore. Green open access
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Jaffer, S; Valasek, P; Luke, G; Batarfi, M; Whalley, BJ; Patel, K; (2016) Characterisation of Development and Electrophysiological Mechanisms Underlying Rhythmicity of the Avian Lymph Heart. PLoS One , 11 (12) , Article e0166428. 10.1371/journal.pone.0166428. Green open access
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James, EC; Hook, J; Stenning, S; Cook, A; Coyle, C; Petrie, J; Kaplan, R; ... Clamp, A; + view all (2016) ICON8 Stage 1A and 1B analysis: safety and feasibility of weekly carboplatin and paclitaxel regimens in first-line ovarian cancer. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

James, ND; Sydes, MR; Clarke, NW; Mason, MD; Dearnaley, DP; Spears, MR; Ritchie, AW; ... STAMPEDE investigators, ; + view all (2016) Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet , 387 (10024) pp. 1163-1177. 10.1016/S0140-6736(15)01037-5. Green open access
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Jansen, M; Wright, NA; (2016) Distal Esophageal Adenocarcinoma and Gastric Adenocarcinoma: Time for a Shared Research Agenda. Stem Cells, Pre-neoplasia, and Early Cancer of the Upper Gastrointestinal Tract , 908 pp. 1-8. 10.1007/978-3-319-41388-4_1.

Johnson, P; Federico, M; Kirkwood, A; Fossa, A; Berkahn, L; Carella, A; d'Amore, F; ... Barrington, S; + view all (2016) Adapted Treatment Guided by Interim PET-CT Scan in Advanced Hodgkin's Lymphoma. New England Journal of Medicine , 374 (25) pp. 2419-2429. 10.1056/NEJMoa1510093. Green open access
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Johnson, SP; Ramasawmy, R; Campbell-Washburn, AE; Wells, JA; Robson, M; Rajkumar, V; Lythgoe, MF; ... Walker-Samuel, S; + view all (2016) Acute changes in liver tumour perfusion measured non-invasively with arterial spin labelling. British Journal of Cancer , 114 (8) pp. 897-904. 10.1038/bjc.2016.51. Green open access
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Johnsson, M; Gering, E; Willis, P; Lopez, S; Van Dorp, L; Hellenthal, G; Henriksen, R; ... Wright, D; + view all (2016) Feralisation targets different genomic loci to domestication in the chicken. Nature Communications , 7 , Article 12950. 10.1038/ncomms12950. Green open access
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Johnston, EW; Pye, H; Bonet Carne, E; Panagiotaki, E; Patel, D; Galazi, M; Heavey, S; ... Punwani, S; + view all (2016) INNOVATE: A prospective cohort study combining serum and urinary biomarkers with novel diffusion-weighted magnetic resonance imaging for the prediction and characterization of prostate cancer. BMC Cancer , 16 (816) 10.1186/s12885-016-2856-2. Green open access
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Jones, C; Harrow, B; Badamgarav, E; Agarwal, S; Ledermann, J; Quinn, C; (2016) Modeling maintenance therapy in ovarian cancer. Presented at: UNSPECIFIED.

Jorgensen, M; (2016) Targeted Therapy for Chordoma. Doctoral thesis , UCL (University College London). Green open access
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Jovanovic, KK; Tanic, M; Ivanovic, I; Gligorijevic, N; Dojcinovic, BP; Radulovic, S; (2016) Cell cycle, apoptosis, cellular uptake and whole-transcriptome microarray gene expression analysis of HeLa cells treated with a ruthenium(II)-arene complex with an isoquinoline-3-carboxylic acid ligand. Journal of Inorganic Biochemistry , 163 pp. 362-373. 10.1016/j.jinorgbio.2016.04.011. Green open access
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Ju, YS; Tubio, JMC; Mifsud, W; Fu, B; Davies, HR; Ramakrishna, M; Li, Y; ... Stratton, MR; + view all (2016) Corrigendum: Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Res , 26 (5) 717.2-. 10.1101/gr.206557.116.

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Kaisaki, PJ; Cutts, A; Popitsch, N; Camps, C; Pentony, MM; Wilson, G; Page, S; ... Taylor, JC; + view all (2016) Targeted Next-Generation Sequencing of Plasma DNA from Cancer Patients: Factors Influencing Consistency with Tumour DNA and Prospective Investigation of Its Utility for Diagnosis. PLoS One , 11 (9) , Article e0162809. 10.1371/journal.pone.0162809. Green open access
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Kalwa, M; Hänzelmann, S; Otto, S; Kuo, CC; Franzen, J; Joussen, S; Fernandez-Rebollo, E; ... Wagner, W; + view all (2016) The lncRNA HOTAIR impacts on mesenchymal stem cells via triple helix formation. Nucleic Acids Research , 44 (22) pp. 10631-10643. 10.1093/nar/gkw802. Green open access
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Kanu, N; Cerone, MA; Goh, G; Zalmas, L-P; Bartkova, J; Dietzen, M; McGranahan, N; ... Swanton, C; + view all (2016) DNA replication stress mediates APOBEC3 family mutagenesis in breast cancer. Genome Biology , 17 , Article 185. 10.1186/s13059-016-1042-9. Green open access
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Kato, I; Nishinaka-Arai, Y; Nakamura, M; Akarca, AU; Niwa, A; Ozawa, H; Yoshida, K; ... Enver, T; + view all (2016) VEGFA- a New Therapeutic Target in CNS Leukemia. Presented at: 58th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), San Diego, CA.

Kerrison, R; McGregor, LM; Marshall, S; Isitt, J; Counsell, N; Wardle, J; Von Wagner, C; (2016) Use of a twelve month's self referral reminder to faciliate uptake of bowel scope (flexible sigmoidoscopy screening) in previous non-responders: a London-based feasibility study. British Journal of Cancer , 114 pp. 751-758. 10.1038/bjc.2016.43. Green open access
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Kerrison, RS; McGregor, LM; Marshall, S; Isitt, J; Counsell, N; Wardle, J; von Wagner, C; (2016) Use of a 12 months' self-referral reminder to facilitate uptake of bowel scope (flexible sigmoidoscopy) screening in previous non-responders: a London-based feasibility study. British Journal of Cancer , 114 (7) pp. 751-758. 10.1038/bjc.2016.43. Green open access
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Khalil, A; Bowles, L; O'Brien, P; Cohen, H; (2016) Systemic thromboembolism in pregnancy: venous thromboembolism. In: Cohen, H and O'Brien, P, (eds.) Disorders in thrombosis and haemostasis in pregnancy: a guide to management. Springer

Khetrapal, P; Feber, A; Kelly, J; Briggs, T; Sridhar, A; Goh, W; Lamb, B; ... Wong, S; + view all (2016) Blood-based liquid biopsy: A comparison between plasma detection of cell-free DNA and circulating tumour cell detection in the detection of bladder cancer. Presented at: UNSPECIFIED.

Khoja, L; Nolan, K; Mekki, R; Milani, A; Mescallado, N; Ashcroft, L; Hasan, J; ... Jayson, GC; + view all (2016) Improved Survival from Ovarian Cancer in Patients Treated in Phase III Trial Active Cancer Centres in the UK. Clinical Oncology , 28 (12) pp. 760-765. 10.1016/j.clon.2016.06.011. Green open access
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Kim, R; Sharma, S; Meyer, T; Sarker, D; Macarulla, T; Sung, M; Choo, SP; ... Llovet, JM; + view all (2016) First-in-human study of BLU-554, a potent, highly-selective FGFR4 inhibitor designed for hepatocellular carcinoma (HCC) with FGFR4 pathway activation. Presented at: 28th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, Munich, GERMANY.

Kinghorn, KJ; Groenke, S; Castillo-Quan, JI; Woodling, NS; Li, L; Sirka, E; Gegg, M; ... Partridge, L; + view all (2016) A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin. JOURNAL OF NEUROSCIENCE , 36 (46) pp. 11654-11670. 10.1523/JNEUROSCI.4527-15.2016. Green open access
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Kinna, A; Tolner, B; Rota, EM; Titchener-Hooker, N; Nesbeth, D; Chester, K; (2016) IMAC capture of recombinant protein from unclarified mammalian cell feed streams. Biotechnology and Bioengineering , 113 (1) pp. 130-140. 10.1002/bit.25705. Green open access
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Koeferle, A; Worf, K; Breunig, C; Baumann, V; Herrero, J; Wiesbeck, M; Hutter, LH; ... Stricker, SH; + view all (2016) CORALINA: a universal method for the generation of gRNA libraries for CRISPR-based screening. BMC Genomics , 17 , Article 917. 10.1186/s12864-016-3268-z. Green open access
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Koffas, A; Watkins, J; Mohmaduvesh, M; Thirlwell, C; Meyer, T; Toumpanakis, C; Caplin, M; (2016) Analysis of Oesophageal Neuroendocrine Tumor Outcomes. Presented at: 57th Annual Meeting and Residents Fellow Conference of the Society-for-Surgery-of-the-Alimentary-Tract (SSAT) / 52nd Annual Meeting on Digestive Disease Week (DDW) / Meeting of the American-Gastroenterological-Association (AGA), San Diego, CA.

Konecny, G; Kristeleit, RS; (2016) PARP inhibitors for BRCA1/2-mutated and sporadic ovarian cancer: current practice and future directions. British Journal of Cancer , 115 pp. 1157-1173. 10.1038/bjc.2016.311. Green open access
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Kotwinski, PJ; Smith, G; Cooper, J; Sanders, J; Ma, L; Teis, A; Kotwinski, D; ... Breast cancer Early disease: Toxicity from Therapy with Epirubic, ; + view all (2016) Body Surface Area and Baseline Blood Pressure Predict Subclinical Anthracycline Cardiotoxicity in Women Treated for Early Breast Cancer. PLOS One , 11 (12) , Article e0165262. 10.1371/journal.pone.0165262. Green open access
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Kramer, AM; Ghorashian, S; Cheung, GWK; Mekkaoui, L; Nannini, F; Onuoha, S; Amrolia, P; (2016) Construction and pre-clinical evaluation of a new anti-CD19 chimeric antigen receptor. Presented at: Conference on Changing the Face of Modern Medicine - Stem Cells and Gene Therapy, Florence, ITALY.

Kristeleit, RS; Miller, RE; Kohn, EC; (2016) Gynecologic Cancers: Emerging Novel Strategies for Targeting DNA Repair Deficiency. American Society of Clinical Oncology Educational Book , 2016 10.14694/EDBK_159086. Green open access
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Kristeleit, RS; Miller, RE; Sellers, LE; Brown, NF; Gougis, P; Boyd, A; Morris, G; ... Linch, M; + view all (2016) A first-in-human (FIH) phase I/II, dose escalation, pharmacokinetic (PK) study to assess the safety and tolerability of VAL-201 in patients with advanced prostate cancer (APC) and other advanced solid tumours. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Kristeleit, RS; Shapira-Frommer, R; Oaknin, A; Balmana, J; Ray-Coquard, IL; Domchek, S; Tinker, AV; ... Oza, A; + view all (2016) Clinical activity of the poly(ADP-ribose) polymerase (PARP) inhibitor rucaparib in patients (pts) with high-grade ovarian carcinoma (HGOC) and a BRCA mutation (BRCAmut): Analysis of pooled data from Study 10 (parts 1, 2a, and 3) and ARIEL2 (parts 1 and 2). Presented at: 41st ESMO Congress (ESMO 2016), Copenhagen, Denmark.

Krusche, B; Ottone, C; clements, MP; Johnstone, ER; Goetsch, K; Lieven, H; Mota, SG; ... Parrinello, S; + view all (2016) EphrinB2 drives perivascular invasion and proliferation of glioblastoma stem-like cells. eLife , 5 , Article e14845. 10.7554/eLife.14845. Green open access
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Kularatne, B; Arora, R; Elshstein, G; Guppy, N; Kirkwood, A; Meyer, T; Kristeleit, RS; (2016) Immunohistochemistry (IHC) evaluation of a novel 4-protein prognostic and predictive biomarker panel in endometrial cancer (EC). In: Abstract Book of the 41st ESMO Congress (ESMO 2016), 7-11 October 2016, Copenhagen, Denmar. Oxford University Press (OUP): Policy A1 Green open access
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Kumar, AJ; Gimotty, PA; Gelfand, J; Buck, G; Rowe, JM; Goldstone, AH; Fielding, A; ... Loren, AW; + view all (2016) Delays in postremission chemotherapy for Philadelphia chromosome negative acute lymphoblastic leukemia are associated with inferior outcomes in patients who undergo allogeneic transplant: An analysis from ECOG 2993/MRC UK ALLXII. American Journal of Hematology , 91 (11) pp. 1107-1112. 10.1002/ajh.24497. Green open access
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Kupka, S; De Miguel, D; Draber, P; Martino, L; Surinova, S; Rittinger, K; Walczak, H; (2016) SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Reports , 16 (9) pp. 2271-2280. 10.1016/j.celrep.2016.07.086. Green open access
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Laethem, J-LV; Riess, H; Jassem, J; Haas, M; Martens, UM; Weekes, C; Peeters, M; ... Childs, BH; + view all (2016) Phase I/II Study of Refametinib (BAY 86-9766) in Combination with Gemcitabine in Advanced Pancreatic cancer. Targeted Oncology , 12 (1) pp. 97-109. 10.1007/s11523-016-0469-y. Green open access
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Lampada, A; (2016) Targeting autophagy in colorectal cancer. Doctoral thesis , UCL (University College London). Green open access
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Landau, DB; Hughes, L; Baker, A; Bates, AT; Bayne, MC; Counsell, N; Garcia-Alonso, A; ... Fenwick, JD; + view all (2016) IDEAL-CRT: A Phase 1/2 Trial of Isotoxic Dose-Escalated Radiation Therapy and Concurrent Chemotherapy in Patients With Stage II/III Non-Small Cell Lung Cancer. International Journal of Radiation Oncology - Biology - Physics , 95 (5) pp. 1367-1377. 10.1016/j.ijrobp.2016.03.031. Green open access
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Laskaratos, F-M; Walker, M; Naik, K; Maragkoudakis, E; Oikonomopoulos, N; Grant, L; Meyer, T; ... Toumpanakis, C; + view all (2016) Predictive factors of antiproliferative activity of octreotide LAR as first-line therapy for advanced neuroendocrine tumours. British Journal of Cancer , 115 (11) pp. 1321-1327. 10.1038/bjc.2016.349. Green open access
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Laurent-Puig, P; Balogoun, R; Cayre, A; Le Malicot, K; Tabernero, J; Mini, E; Folprecht, G; ... Taieb, J; + view all (2016) ERBB2 alterations a new prognostic biomarker in stage III colon cancer from a FOLFOX based adjuvant trial (PETACC8). Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Lawson, C; Vicencio, JM; Yellon, DM; Davidson, SM; (2016) Microvesicles and exosomes: new players in metabolic and cardiovascular disease. Journal of Endocrinology , 228 (2) R57-R71. 10.1530/JOE-15-0201. Green open access
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Lazaryan, A; Wang, T; Spellman, SR; Wang, HL; Pidala, J; Nishihori, T; Askar, M; ... Lee, SJ; + view all (2016) Human leukocyte antigen supertype matching after myeloablative hematopoietic cell transplantation with 7/8 matched unrelated donor allografts: a report from the Center for International Blood and Marrow Transplant Research. Haematologica , 101 (10) pp. 1267-1274. 10.3324/haematol.2016.143271. Green open access
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Le Quesne Stabej, P; Williams, HJ; James, C; Tekman, M; Stanescu, HC; Kleta, R; Ocaka, L; ... GOSgene, ; + view all (2016) STAG3 truncating variant as the cause of primary ovarian insufficiency. European Journal of Human Genetics , 24 (1) pp. 135-138. 10.1038/ejhg.2015.107. Green open access
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Leblond, V; Kastritis, E; Advani, R; Ansell, SM; Buske, C; Castillo, JJ; Garcia-Sanz, R; ... Dimopoulos, MA; + view all (2016) Treatment recommendations from the Eighth International Workshop on Waldenstrom's Macroglobulinemia. Blood , 128 (10) pp. 1321-1328. 10.1182/blood-2016-04-711234. Green open access
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Lechner, M; Fenton, TR; (2016) Chapter One - The Genomics, Epigenomics, and Transcriptomics of HPV-Associated Oropharyngeal Cancer - Understanding the Basis of a Rapidly Evolving Disease. Advances in Genetics , 93 pp. 1-56. 10.1016/bs.adgen.2015.12.001.

Ledermann, J; Fujiwara, K; Vergote, I; Oza, A; Birrer, M; Disilvestro, P; Beck, JT; ... Monk, B; + view all (2016) PHASE 3 TRIAL OF AVELUMAB (ANTI-PD-L1) IN COMBINATION WITH AND/OR FOLLOWING PLATINUM-BASED CHEMOTHERAPY IN PATIENTS WITH UNTREATED OVARIAN CANCER. Presented at: UNSPECIFIED.

Ledermann, JA; (2016) PARP inhibitors in ovarian cancer. Annals of Oncology , 27 (Suppl 1) i40-i44. 10.1093/annonc/mdw094. Green open access
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Ledermann, JA; Drew, Y; Kristeleit, RS; (2016) Homologous recombination deficiency and ovarian cancer. European Journal of Cancer , 60 pp. 49-58. 10.1016/j.ejca.2016.03.005. Green open access
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Ledermann, JA; Embleton, AC; Raja, F; Perren, TJ; Jayson, GC; Rustin, GJS; Kaye, SB; ... Collaborators, I; + view all (2016) Cediranib in patients with relapsed platinum-sensitive ovarian cancer (ICON6): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet , 387 (10023) pp. 1066-1074. 10.1016/S0140-6736(15)01167-8. Green open access
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Ledermann, JA; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; Scott, C; ... Matulonis, U; + view all (2016) Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer. British Journal of Cancer , 115 (11) pp. 1313-1320. 10.1038/bjc.2016.348. Green open access
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Ledermann, JA; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; Scott, C; ... Matulonis, U; + view all (2016) Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial. The Lancet Oncology , 17 (11) pp. 1579-1589. 10.1016/S1470-2045(16)30376-X. Green open access
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Lee, AJX; Benamore, R; Hofer, M; Chitnis, M; (2016) Leptomeningeal carcinomatosis in non-small-cell lung cancer: initial response to erlotinib followed by relapse despite continuing radiological resolution of disease. Oxford Medical Case Reports , 2016 (9) , Article omw069. 10.1093/omcr/omw069. Green open access
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Lee, SM; Falzon, M; Blackhall, F; Spicer, J; Nicolson, M; Chaudhuri, A; Middleton, G; ... Hackshaw, A; + view all (2016) Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET). Journal of Clinical Oncology , 35 (4) pp. 402-411. 10.1200/JCO.2016.68.1841. Green open access
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Lemech, CR; Ensell, L; Paterson, JC; Eminowicz, G; Lowe, H; Arora, R; Arkenau, H-T; ... Kristeleit, RS; + view all (2016) Enumeration and Molecular Characterisation of Circulating Tumour Cells in Endometrial Cancer. Oncology , 91 (1) pp. 48-54. 10.1159/000445999. Green open access
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Leslie, RD; Hawa, MI; Paul, D; Dang, MAN; Tachendorff, A; Lowe, R; Vardhman, RK; (2016) Increased DNA Methylation Variability in Type 1 Diabetes across Three Immune Effector Cell Types. Presented at: 76th Scientific Sessions of the American-Diabetes-Association, New Orleans, LA.

Levine, ME; Lu, AT; Chen, BH; Hernandez, DG; Singleton, AB; Ferrucci, L; Bandinelli, S; ... Horvath, S; + view all (2016) Menopause accelerates biological aging. Proceedings of the National Academy of Sciences of the United States of America , 113 (33) pp. 9327-9332. 10.1073/pnas.1604558113. Green open access
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Lewis, AT; Gaifulina, R; Isabelle, M; Dorney, J; Woods, ML; Lloyd, GR; Lau, K; ... Thomas, GM; + view all (2016) Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells. Journal of Raman Spectroscopy 10.1002/jrs.4980. (In press). Green open access
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Lewis, J; Breeze, CE; Charlesworth, J; Maclaren, OJ; Cooper, J; (2016) Where next for the reproducibility agenda in computational biology? BMC Systems Biology , 10 , Article 52. 10.1186/s12918-016-0288-x. Green open access
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Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Czyz, A; Ruotti, V; ... Beck, S; + view all (2016) Information recovery from low coverage whole-genome bisulfite sequencing. Nature Communications , 7 , Article 11306. 10.1038/ncomms11306. Green open access
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Libertini, E; Heath, SC; Hamoudi, RA; Gut, M; Ziller, MJ; Herrero, J; Czyz, A; ... Beck, S; + view all (2016) Saturation analysis for whole-genome bisulfite sequencing data. [Letter]. Nature Biotechnology , 34 (7) pp. 691-693. 10.1038/nbt.3524. Green open access
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Lidove, O; Barbey, F; Niu, D-M; Brand, E; Nicholls, K; Bizjajeva, S; Hughes, D; (2016) Clinical characteristics and demographics in patients 50 years and older in the Fabry Outcome Survey (FOS). Presented at: 12th Annual WORLD Symposium, San Diego, CA.

Lidove, O; Barbey, F; Niu, DM; Brand, E; Nicholls, K; Bizjajeva, S; Hughes, DA; (2016) Fabry in the older patient: Clinical consequences and possibilities for treatment. Molecular Genetics and Metabolism , 118 (4) pp. 319-325. 10.1016/j.ymgme.2016.05.009. Green open access
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Little, AM; Green, A; Harvey, J; Hemmatpour, S; Latham, K; Marsh, SG; Poulton, K; (2016) BSHI Guideline: HLA matching and donor selection for haematopoietic progenitor cell transplantation. International Journal of Immunogenetics , 43 (5) pp. 263-286. 10.1111/iji.12282. Green open access
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Lloyd, AJ; Gallop, K; Ali, S; Hughes, D; MacCulloch, A; (2016) Social preference weights for treatments in Fabry disease in the UK: a discrete choice experiment. Current Medical Research and Opinion , 33 (1) pp. 23-29. 10.1080/03007995.2016.1232704. Green open access
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Lopez-Guadamillas, E; Fernandez-Marcos, PJ; Pantoja, C; Muñoz-Martin, M; Martínez, D; Gómez-López, G; Campos-Olivas, R; ... Serrano, M; + view all (2016) p21(Cip1) plays a critical role in the physiological adaptation to fasting through activation of PPARα. Sci Rep , 6 , Article 34542. 10.1038/srep34542. Green open access
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Lopez-Guadamillas, E; Muñoz-Martin, M; Martinez, S; Pastor, J; Fernandez-Marcos, PJ; Serrano, M; (2016) PI3Kα inhibition reduces obesity in mice. Aging , 8 (11) pp. 2747-2753. 10.18632/aging.101075. Green open access
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Lorente, D; Omlin, A; Zafeiriou, Z; Nava-Rodrigues, D; Pérez-López, R; Pezaro, C; Mehra, N; ... de Bono, J; + view all (2016) Castration-Resistant Prostate Cancer Tissue Acquisition From Bone Metastases for Molecular Analyses. Clinical Genitourinary Cancer , 14 (6) pp. 485-493. 10.1016/j.clgc.2016.04.016. Green open access
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Maciocia, P; Wawrzyniecka, P; Philip, B; Ricciardelli, I; Akarca, AU; Onuoha, S; Cole, D; ... Pule, MA; + view all (2016) Targeting T-Cell Receptor β-Constant Domain for Immunotherapy of T-Cell Malignancies. Presented at: UNSPECIFIED.

Maciocia, PM; Wawrzyniecka, P; Philip, B; Akarca, A; Marafioti, T; Pule, MA; (2016) Targeting the TCR beta-constant region for specific immunotherapy of T-cell malignancies. Presented at: Conference on Changing the Face of Modern Medicine - Stem Cells and Gene Therapy, Florence, ITALY. Green open access
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Maclean, JD; (2016) Advanced radiation therapies for meningioma. Doctoral thesis , UCL (University College London). Green open access
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Majumder, B; Koganti, S; Lowdell, MW; Rakhit, RD; (2016) Intracoronary platelet and monocyte activation status within platelet-monocyte complexes are determinants of inflammation in ST elevation myocardial infarction1. Clinical Hemorheology and Microcirculation , 64 (1) pp. 35-46. 10.3233/CH-162040. Green open access
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Malhotra, K; Butler, JS; Yu, HM; Selvadurai, S; D'Sa, S; Rabin, N; Kyriakou, C; ... Molloy, S; + view all (2016) Spinal disease in myeloma: cohort analysis at a specialist spinal surgery centre indicates benefit of early surgical augmentation or bracing. BMC Cancer , 16 , Article 444. 10.1186/s12885-016-2495-7. Green open access
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Mandair, D; Vesely, C; Ensell, L; Lowe, H; Spanswick, V; Hartley, JA; Caplin, ME; (2016) A comparison of CellCollector with CellSearch in patients with neuroendocrine tumours. Endocrine-Related Cancer , 23 (10) L29-L32. 10.1530/ERC-16-0201. Green open access
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Marina, NM; Smeland, S; Bielack, SS; Bernstein, M; Jovic, G; Krailo, MD; Hook, JM; ... Whelan, JS; + view all (2016) Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial. The Lancet Oncology , 17 (10) pp. 1396-1408. 10.1016/S1470-2045(16)30214-5. Green open access
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Mary, G; Cunningham, D; Chadwick, N; Counsell, N; Hawkes, EA; McMillan, A; Ardeshna, KM; ... Linch, D; + view all (2016) EVALUATION OF A PROGNOSTIC MODEL FOR CNS RELAPSE WITHIN THE UK NCRI R-CHOP-14 VS 21 TRIAL. Presented at: 21st Congress of the European-Hematology-Association, Copenhagen, DENMARK.

Masetti, R; Castelli, I; Astolfi, A; Bertuccio, SN; Indio, V; Togni, M; Belotti, T; ... Locatelli, F; + view all (2016) Genomic complexity and dynamics of clonal evolution in childhood acute myeloid leukemia studied with whole-exome sequencing. Oncotarget , 7 (35) pp. 56746-56757. 10.18632/oncotarget.10778. Green open access
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Mateo, J; Moreno, V; Gupta, A; Kaye, SB; Dean, E; Middleton, MR; Friedlander, M; ... Molife, LR; + view all (2016) An Adaptive Study to Determine the Optimal Dose of the Tablet Formulation of the PARP Inhibitor Olaparib. Targeted Oncology , 11 (3) pp. 401-415. 10.1007/s11523-016-0435-8. Green open access
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Mattar, C; Biswas, A; Johana, N; Tan, YYW; Rosales, C; McKintosh, J; Tan, L-G; ... Chan, JKY; + view all (2016) Longitudinal Surveillance of Non Human Primate Recipients of Intrauterine Gene Transfer for Coagulation Factor Deficiencies. Presented at: 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), Washington, DC.

Matulonis, U; Herrstedt, J; Oza, A; Mahner, S; Redondo, A; Fabbro, M; Ledermann, J; ... Mirza, MR; + view all (2016) ENGOT-OV16/NOVA: A MAINTENANCE STUDY WITH NIRAPARIB VERSUS PLACEBO IN PATIENTS WITH PLATINUM-SENSITIVE OVARIAN CANCER. Presented at: UNSPECIFIED.

Matulonis, UA; Chen, M; Puhlmann, M; Shentu, Y; Ledermann, J; (2016) KEYNOTE-100: Phase 2 trial of pembrolizumab in patients with advanced recurrent ovarian cancer. Presented at: 41st Annual Congress of the European-Society-for-Medical-Oncology (ESMO), Copenhagen, DENMARK.

Maughan, E; Lesage, F; Butler, CR; Hynds, RE; Hewitt, R; Janes, SM; Deprest, JA; (2016) Airway tissue engineering for congenital laryngotracheal disease. Seminars in Pediatric Surgery , 25 (3) pp. 186-190. 10.1053/j.sempedsurg.2016.02.012. Green open access
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Maybury, B; Cook, G; Pratt, G; Yong, K; Ramasamy, K; (2016) Augmenting Autologous Stem Cell Transplantation to Improve Outcomes in Myeloma. Biology of Blood and Marrow Transplantation , 22 (11) pp. 1926-1937. 10.1016/j.bbmt.2016.06.004. Green open access
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Mayor, NP; Brosnan, N; Midwinter, W; McWhinnie, AJM; Turner, TR; Robinson, J; Bultitude, WP; ... Marsh, SGE; + view all (2016) A MULTIPLEXED TYPING STRATEGY FOR THE HLA CLASS II GENES HLA-DRB1,-DQB1 AND-DPB1 USING DNA BARCODES AND SMRT (R) DNA SEQUENCING. Presented at: UNSPECIFIED.

McCourt, O; Heinrich, M; Fisher, A; Paton, B; Beeken, R; Hackshaw, A; Rismani, A; ... Yong, K; + view all (2016) Use of an 'adapted Zelen' design in a randomised controlled trial of a physiotherapist-led exercise intervention in patients with myeloma. Presented at: th European Congress of the European Region of the World Confederation of Physical Therapy (ER-WCPT), Liverpool, UK. Green open access
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McGregor, L; Von Wagner, C; Atkin, W; Kralj-Hans, I; Halloran, S; Handley, G; Logan, R; ... Wardle, J; + view all (2016) Reducing the social gradient in uptake of the NHS Colorectal Cancer Screening Programme using a narrative-based information leaflet: a cluster-randomised trial. Gastroenterology Research and Practice , 2016 , Article 3670150. 10.1155/2016/3670150. Green open access
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McLean, BA; Zhabyeyev, P; Chen, X; Haromy, A; Vanhaesebroeck, B; Michelakis, ED; Oudit, GY; (2016) PI3K alpha Deletion in Cardiomyocytes Causes Maintained Mitochondrial Membrane Potential and Blocks Necrotic Cell Death in Ischemia/Reperfusion Injury. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

McLean, BA; Zhabyeyev, P; Chen, X; Haromy, A; Vanhaesebroeck, B; Michelakis, ED; Oudit, GY; (2016) PI3K alpha Deletion in Cardiomyocytes Causes Maintained Mitochondrial Membrane Potential and Blocks Necrotic Cell Death in Ischemia/Reperfusion Injury. Presented at: Scientific Sessions of the American-Heart-Association / Resuscitation Science Symposium, New Orleans, LA.

Meghini, F; Martins, T; Tait, X; Fujimitsu, K; Yamano, H; Glover, DM; Kimata, Y; (2016) Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nature Communications , 7 , Article 12607. 10.1038/ncomms12607. Green open access
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Melero, I; Sangro, B; Yau, T; Hsu, C; Kudo, M; Crocenzi, TS; Kim, T-Y; ... El-Khoueiry, AB; + view all (2016) Nivolumab (Nivo) in Patients (Pts) With Advanced Hepatocellular Carcinoma (HCC): the CheckMate 040 Study. Presented at: 67th Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Boston, MA.

Melão, A; Spit, M; Cardoso, BA; Barata, JT; (2016) Optimal IL-7R-mediated signaling, cell cycle progression and viability of T-cell acute lymphoblastic leukemia cells rely on CK2 activity. Haematologica , 101 pp. 1368-1379. 10.3324/haematol.2015.141143. Green open access
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Menezes, S; Melandri, D; Anselmi, G; Perchet, T; Loschko, J; Dubrot, J; Patel, R; ... Guermonprez, P; + view all (2016) The Heterogeneity of Ly6C(hi) Monocytes Controls Their Differentiation into iNOS(+) Macrophages or Monocyte-Derived Dendritic Cells. Immunity , 45 (6) pp. 1205-1218. 10.1016/j.immuni.2016.12.001. Green open access
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Menger, L; Sledzinska, A; Bergerhoff, K; Vargas, FA; Smith, J; Poirot, L; Pule, M; ... Quezada, SA; + view all