UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Browse by UCL Departments and Centres

Up a level
Export as [feed] Atom [feed] RSS 1.0 [feed] RSS 2.0
Group by: Author | Type
Jump to: A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | R | S | T | U | V | W | Y | Z
Number of items: 513.


Abdallah, QMA; Phillips, RM; Johansson, F; Helleday, T; Cosentino, L; Abdel-Rahman, H; Etzad, J; (2012) Minor structural modifications to alchemix influence mechanism of action and pharmacological activity. BIOCHEMICAL PHARMACOLOGY , 83 (11) pp. 1514-1522. 10.1016/j.bcp.2012.02.017.

Adair, JR; Howard, PW; Hartley, JA; Williams, DG; Chester, KA; (2012) Antibody-drug conjugates - a perfect synergy. EXPERT OPINION ON BIOLOGICAL THERAPY , 12 (9) pp. 1191-1206. 10.1517/14712598.2012.693473.

Adams, D; Altucci, L; Antonarakis, SE; Ballesteros, J; Beck, S; Bird, A; Bock, C; (2012) BLUEPRINT to decode the epigenetic signature written in blood. NATURE BIOTECHNOLOGY , 30 (3) pp. 224-226.

Adams, J; Wickremasinghe, RG; Prentice, AG; Strefford, JC; Duncombe, A; Forconi, F; Stevenson, FK; (2012) Phenethyl Isothiocyanate (PEITC) Regulates Autophagy in Chronic Lymphocytic Leukemia. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Agbamu, DA; Day, N; Walsh, CJ; Hendrickse, CW; Langman, G; Pallan, A; Lowe, A; (2012) Feasibility of preoperative chemotherapy for locally advanced, operable colon cancer: The pilot phase of a randomised controlled trial. The Lancet Oncology , 13 (11) 1152 - 1160. 10.1016/S1470-2045(12)70348-0. Green open access

Agostinelli, C; Paterson, JC; Gupta, R; Righi, S; Sandri, F; Piccaluga, PP; Bacci, F; (2012) Detection of LIM domain only 2 (LMO2) in normal human tissues and haematopoietic and non-haematopoietic tumours using a newly developed rabbit monoclonal antibody. HISTOPATHOLOGY , 61 (1) pp. 33-46. 10.1111/j.1365-2559.2012.04198.x.

Aguiar Alpizar, Y; Karwacz, K; Arce, F; Yglesias Rivera, A; Enrique Fernandez, L; Collins, MK; Sanchez Ramirez, B; (2012) Lentiviral vector followed by protein immunisation breaks tolerance against the self-antigen Her1 and results in lung cancer immunotherapy. JOURNAL OF GENE MEDICINE , 14 (3) pp. 151-157. 10.1002/jgm.2606.

Aitchison, KL; Rahim, AA; Hughes, D; Kinnon, C; Waddington, SN; Howe, SJ; (2012) Developing lentiviral vectors for gene therapy of Type I Gaucher Disease. In: (Proceedings) Annual Conference of the British-Society-for-Gene-Therapy (BSGT). (pp. A15-A16). MARY ANN LIEBERT INC

Aksoy, E; Taboubi, S; Torres, D; Delbauve, S; Hachani, A; Whitehead, MA; Pearce, WP; (2012) The p110δ isoform of the kinase PI(3)K controls the subcellular compartmentalization of TLR4 signaling and protects from endotoxic shock. Nat Immunol , 13 (11) pp. 1045-1054. 10.1038/ni.2426.

Al-Thihli, K; Ebrahim, H; Hughes, DA; Patel, M; Tipple, M; Salvarinova, R; Gardiner, J; (2012) A variant of unknown significance in the GLA gene causing diagnostic uncertainty in a young female with isolated hypertrophic cardiomyopathy. GENE , 497 (2) pp. 320-322. 10.1016/j.gene.2012.01.056.

Albers, CA; Paul, DS; Schulze, H; Freson, K; Stephens, JC; Smethurst, PA; Jolley, JD; (2012) Compound inheritance of a low-frequency regulatory SNP and a rare null mutation in exon-junction complex subunit RBM8A causes TAR syndrome. Nat Genet , 44 (4) 435-S2. 10.1038/ng.1083.

Albuquerque, AS; Marques, JG; Silva, SL; Ligeiro, D; Devlin, BH; Dutrieux, J; Cheynier, R; (2012) Human FOXN1-Deficiency Is Associated with αβ Double-Negative and FoxP3+ T-Cell Expansions That Are Distinctly Modulated upon Thymic Transplantation. PLoS ONE , 7 (5) e37042-e37042. 10.1371/journal.pone.0037042.

Alcolea, MP; Casado, P; Rodríguez-Prados, JC; Vanhaesebroeck, B; Cutillas, PR; (2012) Phosphoproteomic analysis of leukemia cells under basal and drug-treated conditions identifies markers of kinase pathway activation and mechanisms of resistance. Mol Cell Proteomics , 11 (8) pp. 453-466. 10.1074/mcp.M112.017483.

Ali, S; Sergeant, R; O'Brien, SG; Foroni, L; Hedgley, C; Gerrard, G; Milojkovic, D; (2012) Dasatinib may overcome the negative prognostic impact of KIR2DS1 in newly diagnosed patients with chronic myeloid leukemia. BLOOD , 120 (3) pp. 697-698. 10.1182/blood-2012-04-421016.

Alikian, M; Gerrard, G; Subramanian, PG; Mudge, K; Foskett, P; Khorashad, JS; Lim, AC; (2012) BCR-ABL1 kinase domain mutations: Methodology and clinical evaluation. AMERICAN JOURNAL OF HEMATOLOGY , 87 (3) pp. 298-304. 10.1002/ajh.22272.

Allen, TJ; Hall, A; Dhillon, AP; Owen, JS; Beard, PC; (2012) Spectroscopic photoacoustic imaging of lipid-rich plaques in the human aorta in the 740 to 1400 nm wavelength range. JOURNAL OF BIOMEDICAL OPTICS , 17 (6) 10.1117/1.JBO.17.6.061209.

Alonso-Dominguez, JM; Grinfeld, J; Alikian, M; Marin, D; Reid, A; Daghistani, M; Apperley, J; (2012) PTCH1 Expression At Diagnosis Reliably Predicts Treatment Failure in Imatinib-Treated Chronic Myeloid Leukaemia Patients. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Altshuler, DM; Durbin, RM; Abecasis, GR; Bentley, DR; Chakravarti, A; Clark, AG; Donnelly, P; (2012) An integrated map of genetic variation from 1,092 human genomes. NATURE , 491 (7422) pp. 56-65. 10.1038/nature11632.

Amé-Thomas, P; Le Priol, J; Yssel, H; Caron, G; Pangault, C; Jean, R; Martin, N; (2012) Characterization of intratumoral follicular helper T cells in follicular lymphoma: role in the survival of malignant B cells. Leukemia , 26 (5) pp. 1053-1063. 10.1038/leu.2011.301.

Anthoney, DA; Naik, J; MacPherson, IRJ; Crawford, D; Hartley, JM; Hartley, JA; Saito, T; (2012) Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses. BMC Cancer , 12 , Article 536. 10.1186/1471-2407-12-536. Green open access

Arce, F; Kochan, G; Breckpot, K; Stephenson, H; Escors, D; (2012) Selective Activation of Intracellular Signalling Pathways in Dendritic Cells for Cancer Immunotherapy. ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY , 12 (1) pp. 29-39.

Arkenau, H-T; Saggese, M; Lemech, C; (2012) Advanced gastric cancer: Is there enough evidence to call second-line therapy standard? WORLD JOURNAL OF GASTROENTEROLOGY , 18 (44) pp. 6376-6378. 10.3748/wjg.v18.i44.6376. Gold open access

Arkenau, HT; Plummer, R; Molife, LR; Olmos, D; Yap, TA; Squires, M; Lewis, S; (2012) A phase I dose escalation study of AT9283, a small molecule inhibitor of aurora kinases, in patients with advanced solid malignancies. Ann Oncol , 23 (5) pp. 1307-1313. 10.1093/annonc/mdr451.

Armstrong, CA; Jones, GD; Anderson, R; Iyer, P; Narayanan, D; Sandhu, J; Singh, R; (2012) DNMTs are required for delayed genome instability caused by radiation. Epigenetics , 7 (8) pp. 892-902. 10.4161/epi.21094.

Arrieta Bolanos, ER; Madrigal, J; Shaw, B; (2012) Functional consequences of TGFB1 polymorphisms in regulatory T cells and haematopoietic stem cell transplantation. Presented at: The Joint 16th International HLA and Immunogenetics Conference/26th European Immunogenetics and Histocompatibility Conference/23rd British Society of Histocompatibilty and Immunogenetics Conference, Liverpool, UK. Green open access

Arrieta Bolanos, ER; Madrigal, JA; Shaw, BE; (2012) Human Leukocyte Antigen Profiles of Latin American Populations: Differential Admixture and Its Potential Impact on Hematopoietic Stem Cell Transplantation. Bone Marrow Research , 2012 , Article 136087. 10.1155/2012/136087. Green open access

Arrieta Bolanos, ER; Madrigal, JA; Shaw, BE; Marsh, SGE; Salazar-Sánchez, L; (2012) The frequency of HLA-B*57:01 and the risk of Abacavir hypersensitivity reactions in the Costa Rica Central Valley Population. Presented at: The Joint 16th International HLA and Immunogenetics Conference/26th European Immunogenetics and Histocompatibility Conference/23rd British Society of Histocompatibilty and Immunogenetics Conference, Liverpool, UK. Green open access

Arrieta-Bolanos, E; Madrigal, JA; Shaw, BE; (2012) FUNCTIONAL CONSEQUENCES OF TGFB1 POLYMORPHISMS IN REGULATORY T CELLS AND HEMATOPOIETIC STEM CELL TRANSPLANTATION. Presented at: Joint 16th International HLA and Immunogenetics Workshop/26th European Federation for Immunogenetics Conference/23rd British-Society-of-Histocompatibility-and-Immunogenetics Conference, Liverpool, ENGLAND. Green open access

Arrieta-Bolanos, E; Madrigal, JA; Shaw, BE; (2012) Transforming growth factor-ss 1 polymorphisms and the outcome of hematopoietic stem cell transplantation. INTERNATIONAL JOURNAL OF IMMUNOGENETICS , 39 (3) pp. 192-202. 10.1111/j.1744-313X.2012.01089.x.

Arrieta-Bolaños, E; Madrigal, JA; Shaw, BE; (2012) Transforming growth factor-β1 polymorphisms and the outcome of hematopoietic stem cell transplantation. Int J Immunogenet , 39 (3) pp. 192-202. 10.1111/j.1744-313X.2012.01089.x.

Artim-Esen, B; Pericleous, C; Mackie, I; Ioannou, Y; Rahman, A; Isenberg, DA; Giles, I; (2012) ANTI-Factor Xa Antibodies ARE Significantly Increased in Patients with Systemic LUPUS Erythematosus and Antiphospholipid Syndrome. In: (Proceedings) Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP). (pp. S739-S739). WILEY-BLACKWELL

Asghar, U; Meyer, T; (2012) Are there opportunities for chemotherapy in the treatment of hepatocellular cancer? JOURNAL OF HEPATOLOGY , 56 (3) pp. 686-695.

Aslan, D; Akata, RF; Holme, H; Vulliamy, T; Dokal, I; (2012) Limbal stem cell deficiency in patients with inherited stem cell disorder of dyskeratosis congenita. Int Ophthalmol , 32 (6) pp. 615-622. 10.1007/s10792-012-9611-8.

Aydinok, Y; Evans, P; Manz, CY; Porter, JB; (2012) Timed non-transferrin bound iron determinations probe the origin of chelatable iron pools during deferiprone regimens and predict chelation response. HAEMATOLOGICA-THE HEMATOLOGY JOURNAL , 97 (6) pp. 835-841. 10.3324/haematol.2011.056317.


BENJAMIN, R; (2012) Antiangiogenic strategies for the treatment of haematological malignancies. Doctoral thesis, UCL (University College London). Green open access

Babb, A; Farah, N; Lyons, C; Lindsay, K; Reddy, N; Goldman, J; Apperley, JF; (2012) Uptake and outcome of assisted reproductive techniques in long-term survivors of SCT. Bone Marrow Transplant , 47 (4) pp. 568-573. 10.1038/bmt.2011.134.

Bachner, M; Loriot, Y; Gross-Goupil, M; Zucali, PA; Horwich, A; Germa-Lluch, J-R; Kollmannsberger, C; (2012) 2-(18)fluoro-deoxy-D-glucose positron emission tomography (FDG-PET) for postchemotherapy seminoma residual lesions: a retrospective validation of the SEMPET trial. ANNALS OF ONCOLOGY , 23 (1) pp. 59-64. 10.1093/annonc/mdr052.

Bagnobianchi, A; Spanswick, VJ; Bingham, JP; Kiakos, K; Suarez-Henriques, P; Smith, D; Yong, K; (2012) Persistence of drug-induced DNA interstrand cross-links distinguishes bendamustine from conventional DNA cross-linking agents. CANCER RESEARCH , 72 10.1158/1538-7445.AM2012-1766.

Ballabio, E; Armesto, M; Breeze, CE; Manterola, L; Arestin, M; Tramonti, D; Hatton, CS; (2012) Bortezomib action in multiple myeloma: microRNA-mediated synergy (and miR-27a/CDK5 driven sensitivity)? Blood Cancer J , 2 , Article e83. 10.1038/bcj.2012.31.

Bates, AW; (2012) Diagnosing eosinophilic colitis: histopathological pattern or nosological entity? Scientifica , 2012 , Article 682576. 10.6064/2012/682576. Green open access

Bates, AW; (2012) Morbid Curiosities: Medical Museums in Nineteenth-Century Britain. UNIV CHICAGO PRESS

Bates, AW; Ram, M; (2012) Fibro-osteochondroma of the uterus. Indian Journal of Pathology and Microbiology , 55 (4) 555 - 556. 10.4103/0377-4929.107814. Green open access

Baud, MG; Leiser, T; Haus, P; Samlal, S; Wong, AC; Wood, RJ; Petrucci, V; (2012) Defining the mechanism of action and enzymatic selectivity of psammaplin A against its epigenetic targets. J Med Chem , 55 (4) pp. 1731-1750. 10.1021/jm2016182.

Becerra, E; Leandro, MJ; Heelas, EO; Westwood, JP; de la Torre, I; Scully, MA; Cambridge, G; (2012) B Cell Activating Factor Receptor Expression After Rituximab: Comparison of Patients with Rheumatoid Arthritis and Thrombotic Thrombocytopenic Purpura. In: (Proceedings) Annual Scientific Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP). (pp. S752-S752). WILEY-BLACKWELL


Beck, S; Bernstein, BE; Campbell, RM; Costello, JF; Dhanak, D; Ecker, JR; Greally, JM; (2012) A Blueprint for an International Cancer Epigenome Consortium. A Report from the AACR Cancer Epigenome Task Force. CANCER RESEARCH , 72 (24) pp. 6319-6324. 10.1158/0008-5472.CAN-12-3658.

Beggs, AD; Domingo, E; McGregor, M; Presz, M; Johnstone, E; Midgley, R; Kerr, D; (2012) Loss of expression of ATM is associated with worse prognosis in colorectal cancer and loss of Ku70 expression is associated with CIN. ONCOTARGET , 3 (11) pp. 1348-1355.

Bell, CG; Wilson, GA; Butcher, LM; Roos, C; Walter, L; Beck, S; (2012) Human-specific CpG "beacons" identify loci associated with human-specific traits and disease. Epigenetics , 7 (10) 1188 - 1199. 10.4161/epi.22127. Green open access


Bennett, CL; Chakraverty, R; (2012) Dendritic cells in tissues: in situ stimulation of immunity and immunopathology. TRENDS IN IMMUNOLOGY , 33 (1) pp. 8-13. 10.1016/j.it.2011.09.008.

Berenjeno, IM; Guillermet-Guibert, J; Pearce, W; Gray, A; Fleming, S; Vanhaesebroeck, B; (2012) Both p110α and p110β isoforms of PI3K can modulate the impact of loss-of-function of the PTEN tumour suppressor. Biochem J , 442 (1) pp. 151-159. 10.1042/BJ20111741.

Bez, C.; (2012) The role of the telomere bouquet in controlling spindle pole body composition in fission yeast meiosis. Doctoral thesis, UCL (University College London). Green open access

Bhosle, J.; (2012) Modulation of DNA strand break induction and repair by tyrosine kinase inhibitors targeted against EGFR and HER2. Doctoral thesis, UCL (University College London). Green open access

Biegstraaten, M; Wesnes, KA; Luzy, C; Petakov, M; Mrsic, M; Niederau, C; Giraldo, P; (2012) The cognitive profile of type 1 Gaucher disease patients. JOURNAL OF INHERITED METABOLIC DISEASE , 35 (6) pp. 1093-1099. 10.1007/s10545-012-9460-7.

Bird-Lieberman, EL; Dunn, JM; Coleman, HG; Lao-Sirieix, P; Oukrif, D; Moore, CE; Varghese, S; (2012) Population-Based Study Reveals New Risk-Stratification Biomarker Panel for Barrett's Esophagus. GASTROENTEROLOGY , 143 (4) 927-+. 10.1053/j.gastro.2012.06.041.

Birkbak, NJ; Wang, ZC; Kim, JY; Eklund, AC; Li, Q; Tian, R; Bowman-Colin, C; (2012) Telomeric allelic imbalance indicates defective DNA repair and sensitivity to DNA-damaging agents. Cancer Discov , 2 (4) pp. 366-375. 10.1158/2159-8290.CD-11-0206.

Bolton-Maggs, PHB; Chapman, C; Mistry, H; Williamson, L; Cohen, H; (2012) Continued absence of transfusion-associated graft versus host disease despite failures to provide irradiated products to patients at risk - more than a decade of data from SHOT. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. pp. 3-4). WILEY-BLACKWELL

Bolton-Maggs, PHB; Cohen, H; (2012) Serious hazards of transfusion haemovigilance - The UK experience. European Oncology and Haematology , 8 (2) pp. 127-129.

Bolton-Maggs, PHB; Davies, T; Poles, D; Ball, J; Cohen, H; (2012) Errors in administration of anti-D immunoglobulin to prevent RhD haemolytic disease of the fetus and newborn: mothers and babies put at risk. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. p. 79). WILEY-BLACKWELL

Boshoff, C; (2012) Ephrin receptor: a door to KSHV infection. NATURE MEDICINE , 18 (6) pp. 861-863. 10.1038/nm.2803.

Bridge, G; Monteiro, R; Henderson, S; Emuss, V; Lagos, D; Georgopoulou, D; Patient, R; (2012) The microRNA-30 family targets DLL4 to modulate endothelial cell behavior during angiogenesis. BLOOD , 120 (25) pp. 5063-5072. 10.1182/blood-2012-04-423004.

Brown, J; Woolhouse, I; Harrison, R; Jeebun, V; Munavvar, M; Ng, B; Falzon, M; (2012) Suitability of EBUS-TBNA specimens for the subtyping and genotyping of non-small cell lung cancer: a multi-centre pragmatic implementation study of 774 patients. LUNG CANCER , 75 S18-S18.

Brown, JH; Tellez, J; Wilson, V; Mackie, IJ; Scully, M; Tredger, MM; Moore, I; (2012) Postpartum aHUS Secondary to a Genetic Abnormality in Factor H Acquired Through Liver Transplantation. AMERICAN JOURNAL OF TRANSPLANTATION , 12 (6) pp. 1632-1636. 10.1111/j.1600-6143.2012.03991.x.

Brown, N.J.; (2012) Characterisation of the centrosome protein Cep63. Doctoral thesis, UCL (University College London). Green open access

Bruno, S; Tu, VL; Grillo, F; Isgro, G; Tsochatzis, E; Hall, AR; Dhillon, AP; (2012) Liver collagen proportionate area and septal thickness/nodule size: a comparison for predicting decompensation in cirrhosis. In: (Proceedings) 63rd Annual Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD). (pp. 932A-933A). WILEY-BLACKWELL


Cain, RJ; Vanhaesebroeck, B; Ridley, AJ; (2012) Different PI 3-kinase inhibitors have distinct effects on endothelial permeability and leukocyte transmigration. Int J Biochem Cell Biol , 44 (11) pp. 1929-1936. 10.1016/j.biocel.2012.07.009.

Calabretta, B; Salomoni, P; (2012) Suppression of autophagy by BCR/ABL. Front Biosci (Schol Ed) , 4 pp. 453-460.

Calleja-Agius, J; Jauniaux, E; Pizzey, AR; Muttukrishna, S; (2012) Investigation of systemic inflammatory response in first trimester pregnancy failure. HUMAN REPRODUCTION , 27 (2) pp. 349-357. 10.1093/humrep/der402.

Calvaruso, V; Dhillon, AP; Tsochatzis, E; Manousou, P; Grillo, F; Germani, G; Patch, D; (2012) Liver collagen proportionate area predicts decompensation in patients with recurrent hepatitis C virus cirrhosis after liver transplantation. JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY , 27 (7) pp. 1227-1232. 10.1111/j.1440-1746.2012.07136.x.

Cameron, D; Barrett-Lee, P; Canney, P; Banerji, J; Bartlett, J; Bloomfield, D; Bowden, S; (2012) Abstract S3-3: The UK TACT2 Trial: comparison of standard vs accelerated epirubicin in patients requiring chemotherapy for early breast cancer (EBC) (CRUK/05/019). In: (pp. S3-3-S3-3).

Camilleri, RS; Scully, M; Thomas, M; Mackie, IJ; Liesner, R; Chen, WJ; Manns, K; (2012) A phenotype-genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom. JOURNAL OF THROMBOSIS AND HAEMOSTASIS , 10 (9) pp. 1792-1801. 10.1111/j.1538-7836.2012.04852.x.

Camilleri, RS; Scully, M; Thomas, M; Mackie, IJ; Liesner, R; Chen, WJ; Manns, K; (2012) A phenotype-genotype correlation of ADAMTS13 mutations in congenital thrombotic thrombocytopenic purpura patients treated in the United Kingdom. Journal of Thrombosis and Haemostasis , 10 (9) pp. 1792-1801. 10.1111/j.1538-7836.2012.04852.x.

Campa, D; Butterbach, K; Slager, SL; Skibola, CF; de Sanjosé, S; Benavente, Y; Becker, N; (2012) A comprehensive study of polymorphisms in the ABCB1, ABCC2, ABCG2, NR1I2 genes and lymphoma risk. Int J Cancer , 131 (4) pp. 803-812. 10.1002/ijc.26436.

Campbell, NH; Abd Karim, NH; Parkinson, GN; Gunaratnam, M; Petrucci, V; Todd, AK; Vilar, R; (2012) Molecular Basis of Structure-Activity Relationships between Salphen Metal Complexes and Human Telomeric DNA Quadruplexes. JOURNAL OF MEDICINAL CHEMISTRY , 55 (1) pp. 209-222. 10.1021/jm201140v.

Canzonetta, C; Hoischen, A; Giarin, E; Basso, G; Veltman, JA; Nacheva, E; Nizetic, D; (2012) Amplified segment in the 'Down syndrome critical region' on HSA21 shared between Down syndrome and euploid AML-M0 excludes RUNX1, ERG and ETS2. Br J Haematol , 157 (2) pp. 197-200. 10.1111/j.1365-2141.2011.08985.x.

Carmichael, CL; Metcalf, D; Henley, KJ; Kruse, EA; Di Rago, L; Mifsud, S; Alexander, WS; (2012) Hematopoietic overexpression of the transcription factor Erg induces lymphoid and erythro-megakaryocytic leukemia. Proc Natl Acad Sci U S A , 109 (38) pp. 15437-15442. 10.1073/pnas.1213454109.

Carpenter, B; Ghorashian, S; Nicholson, E; Griffin, J; Ahmadi, M; Zhang, L; Holler, A; (2012) Targeting therapeutic T cells to tumour niches. In: (Proceedings) European Congress of Immunology. (pp. pp. 53-54). WILEY-BLACKWELL

Carpenter, B; Ghorashian, S; Nicholson, E; Griffin, JE; Ahmadi, M; Holler, A; Flutter, B; (2012) Targeting Therapeutic T Cells to Tumour Niches. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Carvalho, A; Cunha, C; Almeida, AJ; Osório, NS; Saraiva, M; Teixeira-Coelho, M; Pedreiro, S; (2012) The rs5743836 polymorphism in TLR9 confers a population-based increased risk of non-Hodgkin lymphoma. Genes Immun , 13 (2) pp. 197-201. 10.1038/gene.2011.59.

Castleton, A; Ghorani, E; Zhang, C; Dey, A; Patel, B; Rai, L; Ehlam, M; (2012) Mesenchymal Stromal Cells Are Promising Candidates as Delivery Vehicles for Systemic Oncolytic Measles Virotherapy in Models of Acute Lymphoblastic Leukaemia. In: (Proceedings) 15th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). (pp. S211-S211). NATURE PUBLISHING GROUP

Chakraverty, R; (2012) Do educated natural killer cells make the grade in treating acute myeloid leukemia? HAEMATOLOGICA-THE HEMATOLOGY JOURNAL , 97 (11) p. 1617. 10.3324/haematol.2012.078717.

Chapman, MH; Tidswell, R; Dooley, JS; Sandanayake, NS; Cerec, V; Deheragoda, M; Lee, AJX; (2012) Whole genome RNA expression profiling of endoscopic biliary brushings provides data suitable for biomarker discovery in cholangiocarcinoma. JOURNAL OF HEPATOLOGY , 56 (4) pp. 877-885.

Chatterjee, R; Shah, FT; Davis, BA; Byers, M; Sooranna, D; Bajoria, R; Pringle, J; (2012) Prospective study of histomorphometry, biochemical bone markers and bone densitometric response to pamidronate in beta-thalassaemia presenting with osteopenia-osteoporosis syndrome. BRITISH JOURNAL OF HAEMATOLOGY , 159 (4) pp. 462-471. 10.1111/bjh.12048.

Chen, C; Constantinou, A; Chester, KA; Vyas, B; Canis, K; Haslam, SM; Dell, A; (2012) Glycoengineering Approach to Half-Life Extension of Recombinant Biotherapeutics. BIOCONJUGATE CHEMISTRY , 23 (8) pp. 1524-1533. 10.1021/bc200624a.

Chen, P; Tu, X; Akdemir, F; Chew, SK; Rothenfluh, A; Abrams, JM; (2012) Effectors of alcohol-induced cell killing in Drosophila. Cell Death Differ , 19 (10) pp. 1655-1663. 10.1038/cdd.2012.47.

Chervova, O; (2012) The massless Dirac equation from the continuum mechanics and microlocal analysis perspectives. Doctoral thesis, UCL (University College London). Green open access

Chervova, O; Vassiliev, D; (2012) Modelling the neutrino in terms of cosserat elasticity. 12th Marcel Grossmann Meeting on Recent Dev. in Theoretical and Experimental General Relativity, Astrophysics and Relativistic Field Theories - Proc. of the MG 2009 Meeting on General Relativity pp. 2398-2400.

Chiesa, R; Gilmour, K; Qasim, W; Adams, S; Worth, AJJ; Zhan, H; Montiel-Equihua, CA; (2012) Omission of in vivo T-cell depletion promotes rapid expansion of naive CD4(+) cord blood lymphocytes and restores adaptive immunity within 2 months after unrelated cord blood transplant. BRITISH JOURNAL OF HAEMATOLOGY , 156 (5) pp. 656-666. 10.1111/j.1365-2141.2011.08994.x.

Clarke, L; Zheng-Bradley, X; Smith, R; Kulesha, E; Xiao, C; Toneva, I; Vaughan, B; (2012) The 1000 Genomes Project: data management and community access. Nat Methods , 9 (5) pp. 459-462. 10.1038/nmeth.1974.

Coats, CJ; Paresi, V; Ramos, M; Janagarajan, K; O'Mahony, C; Dawnay, A; Mehta, A; (2012) Role of serum NT-proBNP measurement in the diagnosis of early cardiac involvement in patients with anderson-fabry disease. In: (Proceedings) Congress of the European-Society-of-Cardiology (ESC). (pp. p. 861). OXFORD UNIV PRESS

Cohen, H; Bolton-Maggs, P; (2012) Breaking records in blood transfusion safety. TRANSFUSION MEDICINE , 22 (4) pp. 241-243. 10.1111/j.1365-3148.2012.01174.x.

Cohen, H; Bolton-Maggs, PHB; Ball, J; Chapman, C; (2012) Too much blood, too quickly: avoiding hazards associated with transfusion-associated circulatory overload (TACO) identified by SHOT reporting. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. p. 17). WILEY-BLACKWELL

Cohen, H; Mackie, IJ; Westwood, JP; Chitolie, A; Liesner, R; Machin, SJ; (2012) Prothrombin/phosphatidyl serine antibodies in patients with antiphospholipid antibodies. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. pp. 33-34). WILEY-BLACKWELL

Cohen, H; Williamson, LM; (2012) Setting up a National Hemovigilance System: SHOT. In: Hemovigilance: An Effective Tool for Improving Transfusion Safety. (pp. 168-179).

Cohen, H; Williamson, LM; (2012) SHOT UK: setting up a haemovigilance scheme. In: de Vries, R and Faber, JC and Robillard, P, (eds.) Haemovigilance. Blackwell-Wiley

Conlan, T; Sivakumaran, J; Fallah-Arani, F; Zhang, L; Means, T; Geissman, F; Chakraverty, R; (2012) Investigating the role of cutaneous dendritic cells in T-cell mediated immunopathology. In: (Proceedings) European Congress of Immunology. (pp. p. 479). WILEY-BLACKWELL

Cox, ST; Madrigal, JA; Saudemont, A; (2012) Three novel allelic variants of the RAET1E/ULBP4 gene in humans. TISSUE ANTIGENS , 80 (4) pp. 390-392. 10.1111/j.1399-0039.2012.01933.x.




Della Peruta, M; Binny, C; Nathwani, D; McIntosh, J; Rosales, C; Davidoff, AM; Williams, R; (2012) DEVELOPMENT OF A LIVER-SPECIFIC, TUMOUR-SELECTIVE RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR TO TARGET HEPATOCELLULAR CARCINOMA. In: (Proceedings) 47th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL). (pp. S111-S111). ELSEVIER SCIENCE BV

Della Peruta, M; Binny, C; Nathwani, D; McIntosh, J; Rosales, C; Davidoff, AM; Williams, R; (2012) DEVELOPMENT OF A LIVER-SPECIFIC, TUMOUR-SELECTIVE RECOMBINANT ADENO-ASSOCIATED VIRUS VECTOR TO TARGET HEPATOCELLULAR CARCINOMA. GUT , 61 A201-A201. 10.1136/gutjnl-2012-302514c.43.

Dessimoz, C; Gabaldón, T; Roos, DS; Sonnhammer, EL; Herrero, J; Quest for Orthologs Consortium, ; (2012) Toward community standards in the quest for orthologs. Bioinformatics , 28 (6) pp. 900-904. 10.1093/bioinformatics/bts050.

Dey, A; Zhang, Y; Castleton, A; Patel, B; Ghorani, E; Rai, L; Elham, M; (2012) Polymorphonuclear Neutrophils(PMNs) Are Cytotoxic for Measles Virus (MV)-Infected Tumor Cells Ex-Vivo, but Their Role in MV-Mediated Oncolysis In-Vivo Is Tumor-Type Dependent. In: (Proceedings) 15th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT). (pp. S271-S271). NATURE PUBLISHING GROUP

Dignan, FL; (2012) Novel strategies for managing graft-versus-host disease. Doctoral thesis, UCL (University College London).

Dignan, FL; Amrolia, P; Clark, A; Cornish, J; Jackson, G; Mahendra, P; Scarisbrick, JJ; (2012) Diagnosis and management of chronic graft-versus-host disease. Br J Haematol , 158 (1) pp. 46-61. 10.1111/j.1365-2141.2012.09128.x.

Dignan, FL; Clark, A; Amrolia, P; Cornish, J; Jackson, G; Mahendra, P; Scarisbrick, JJ; (2012) Diagnosis and management of acute graft-versus-host disease. Br J Haematol , 158 (1) pp. 30-45. 10.1111/j.1365-2141.2012.09129.x.

Dignan, FL; Greenblatt, D; Cox, M; Cavenagh, J; Oakervee, H; Apperley, JF; Fielding, AK; (2012) Efficacy of bimonthly extracorporeal photopheresis in refractory chronic mucocutaneous GVHD. BONE MARROW TRANSPLANTATION , 47 (6) pp. 824-830. 10.1038/bmt.2011.186.

Dignan, FL; Greenblatt, D; Cox, M; Cavenagh, J; Oakervee, H; Apperley, JF; Fielding, AK; (2012) Efficacy of bimonthly extracorporeal photopheresis in refractory chronic mucocutaneous GVHD. Bone Marrow Transplantation , 47 (6) pp. 824-830. 10.1038/bmt.2011.186.

Dignan, FL; Scarisbrick, JJ; Cornish, J; Clark, A; Amrolia, P; Jackson, G; Mahendra, P; (2012) Organ-specific management and supportive care in chronic graft-versus-host disease. BRITISH JOURNAL OF HAEMATOLOGY , 158 (1) pp. 62-78. 10.1111/j.1365-2141.2012.09131.x.

Direkze, S; Mansour, M; Rodriguez-Justo, M; Kibbler, C; Gant, V; Peggs, KS; (2012) Candida kefyr fungal enteritis following autologous BMT. Bone Marrow Transplant , 47 (3) pp. 465-466. 10.1038/bmt.2011.112.

Dobricic, V; Stefanova, E; Jankovic, M; Gurunlian, N; Novakovic, I; Hardy, J; Kostic, V; (2012) Genetic testing in familial and young-onset Alzheimer's disease: mutation spectrum in a Serbian cohort. NEUROBIOLOGY OF AGING , 33 (7) 10.1016/j.neurobiolaging.2011.12.007.

Dong, G; Huang, Y; Yan, Q; Chanudet, E; Ye, H; Liu, H; Isaacson, PG; (2012) A rare case of gastric MALT lymphoma resistant to multiple treatment regimens. J Clin Pathol , 65 (11) pp. 1049-1050. 10.1136/jclinpath-2012-200956.

Dubois, E; Jacoby, M; Blockmans, M; Pernot, E; Schiffmann, SN; Foukas, LC; Henquin, J-C; (2012) Developmental defects and rescue from glucose intolerance of a catalytically-inactive novel Ship2 mutant mouse. CELLULAR SIGNALLING , 24 (11) pp. 1971-1980. 10.1016/j.cellsig.2012.06.012.

Duhamel, LAE; Ye, H; Halai, D; Idowu, BD; Presneau, N; Tirabosco, R; Flanagan, AM; (2012) Frequency of Mouse Double Minute 2 (MDM2) and Mouse Double Minute 4 (MDM4) amplification in parosteal and conventional osteosarcoma subtypes. HISTOPATHOLOGY , 60 (2) pp. 357-359. 10.1111/j.1365-2559.2011.04023.x.

Dunham, I; Kundaje, A; Aldred, SF; Collins, PJ; Davis, C; Doyle, F; Epstein, CB; (2012) An integrated encyclopedia of DNA elements in the human genome. NATURE , 489 (7414) pp. 57-74. 10.1038/nature11247.

Dunlop, MG; Dobbins, SE; Farrington, SM; Jones, AM; Palles, C; Whiffin, N; Tenesa, A; (2012) Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk. Nat Genet , 44 (7) pp. 770-776. 10.1038/ng.2293.

Duran, R; McNeill, A; Mehta, A; Hughes, D; Cox, T; Deegan, P; Schapira, AHV; (2012) Novel pathogenic mutations in the glucocerebrosidase locus. MOLECULAR GENETICS AND METABOLISM , 106 (4) pp. 495-497. 10.1016/j.ymgme.2012.05.006. Gold open access

de Groot, NG; Otting, N; Robinson, J; Blancher, A; Lafont, BAP; Marsh, SGE; O'Connor, DH; (2012) Nomenclature report on the major histocompatibility complex genes and alleles of Great Ape, Old and New World monkey species. IMMUNOGENETICS , 64 (8) pp. 615-631. 10.1007/s00251-012-0617-1.


Ebrahim, HY; Baker, RJ; Mehta, AB; Hughes, DA; (2012) Functional analysis of variant lysosomal acid glycosidases of Anderson-Fabry and Pompe disease in a human embryonic kidney epithelial cell line (HEK 293 T). JOURNAL OF INHERITED METABOLIC DISEASE , 35 (2) pp. 325-334. 10.1007/s10545-011-9395-4.

El-Andaloussi, S; Lee, Y; Lakhal-Littleton, S; Li, J; Seow, Y; Gardiner, C; Alvarez-Erviti, L; (2012) Exosome-mediated delivery of siRNA in vitro and in vivo. NATURE PROTOCOLS , 7 (12) pp. 2112-2126. 10.1038/nprot.2012.131.

El-Andaloussi, S; Lee, Y; Lakhal-Littleton, S; Li, J; Seow, Y; Gardiner, C; Alvarez-Erviti, L; (2012) Exosome-mediated delivery of siRNA in vitro and in vivo. Nature Protocols , 7 (12) pp. 2112-2126. 10.1038/nprot2012131.

El-Sharkawi, D; Ali, A; Evans, CM; Hills, RK; Burnett, AK; Linch, DC; Gale, RE; (2012) ASXL1 mutations are infrequent in young patients with primary acute myeloid leukaemia. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. p. 56). WILEY-BLACKWELL

El-Sharkawi, D; Basu, S; Ocampo, C; Qian, W; D'Sa, S; Hoskin, PJ; Ardeshna, KM; (2012) Elevated lactate dehydrogenase levels detected during routine follow-up do not predict relapse in patients with diffuse large B-cell lymphoma who achieve complete remission after primary treatment with rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone-like immunochemotherapy. Leuk Lymphoma , 53 (10) pp. 1949-1952. 10.3109/10428194.2012.679360.

El-Sharkawi, D; Fisher, C; Khambadkone, S; Stephens, AD; Porter, JB; (2012) SECONDARY ERYTHROCYTOSIS DUE TO COMPOUND HOMOZYGOSITY, BUT NOT COMPOUND HETEROZYGOSITY, FOR Hb LUTON AND alpha-THALASSEMIA: A FAMILY STUDY. HEMOGLOBIN , 36 (1) pp. 7-17. 10.3109/03630269.2011.641134.

Elliott, MJ; De Coppi, P; Speggiorin, S; Roebuck, D; Butler, CR; Samuel, E; Crowley, C; (2012) Stem-cell-based, tissue engineered tracheal replacement in a child: a 2-year follow-up study. LANCET , 380 (9846) pp. 994-1000. 10.1016/S0140-6736(12)60737-5.

Engstroem, PG; Tommei, D; Stricker, SH; Ender, C; Pollard, SM; Bertone, P; (2012) Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival. GENOME MEDICINE , 4 (ARTN 76) 10.1186/gm377.

Erkan, D; Rahman, A; Cohen, H; Machin, SJ; Pierangeli, SS; (2012) What are the potential future treatments in antiphospholipid syndrome? In: Antiphospholipid Syndrome: Insights and Highlights from the 13Th International Congress on Antiphospholipid Antibodies. (pp. 261-287).

Erturan, G; Holme, H; Cassoni, A; Tirabosco, R; Pollock, R; Briggs, T; Michelagnoli, M; (2012) The importance of patient reported functional outcome in paediatric desmoid fibromatosis. Rare Tumors , 4 (3) , Article e38. 10.4081/rt.2012.e38.

Erturan, G; Holme, H; Iyer, S; (2012) Corynebacterium pseudodiphtheriticum septic arthritis secondary to intra-articular injection--a case report and literature review. J Med Microbiol , 61 (Pt 6) pp. 860-863. 10.1099/jmm.0.037937-0.

Erturan, G; Holme, H; Smith, R; Dodds, R; Iyer, S; (2012) Successful use of daptomycin in Panton-Valentine leucocidin positive Staphylococcus aureus paediatric osteomyelitis. Int J Surg Case Rep , 3 (7) pp. 238-241. 10.1016/j.ijscr.2012.03.014.


Faelber, K; Held, M; Gao, S; Posor, Y; Haucke, V; Noé, F; Daumke, O; (2012) Structural insights into dynamin-mediated membrane fission. Structure , 20 (10) pp. 1621-1628. 10.1016/j.str.2012.08.028.

Fagone, P; Wright, JF; Nathwani, AC; Nienhuis, AW; Davidoff, AM; Gray, JT; (2012) Systemic Errors in Quantitative Polymerase Chain Reaction Titration of Self-Complementary Adeno-Associated Viral Vectors and Improved Alternative Methods. HUMAN GENE THERAPY METHODS , 23 (1) pp. 1-7. 10.1089/hgtb.2011.104.

Falchook, GS; Long, GV; Kurzrock, R; Kim, KB; Arkenau, TH; Brown, MP; Hamid, O; (2012) Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial. Lancet , 379 (9829) pp. 1893-1901. 10.1016/S0140-6736(12)60398-5.

Falk, A; Koch, P; Kesavan, J; Takashima, Y; Ladewig, J; Alexander, M; Wiskow, O; (2012) Capture of neuroepithelial-like stem cells from pluripotent stem cells provides a versatile system for in vitro production of human neurons. PLOS One , 7 (1) , Article e29597. 10.1371/journal.pone.0029597. Green open access

Feng, H; Hu, B; Jarzynka, MJ; Li, Y; Keezer, S; Johns, TG; Tang, CK; (2012) Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis. Proc Natl Acad Sci U S A , 109 (8) pp. 3018-3023. 10.1073/pnas.1121457109.

Fennell, DA; Swanton, C; (2012) Unlocking Pandora's box: personalising cancer cell death in non-small cell lung cancer. EPMA J , 3 (1) 6-. 10.1186/1878-5085-3-6.

Fenton, TR; Nathanson, D; Ponte de Albuquerque, C; Kuga, D; Iwanami, A; Dang, J; Yang, H; (2012) Resistance to EGF receptor inhibitors in glioblastoma mediated by phosphorylation of the PTEN tumor suppressor at tyrosine 240. PNAS USA , 109 (35) 14164 - 14169. 10.1073/pnas.1211962109. Green open access

Fernandez, AF; Assenov, Y; Ignacio Martin-Subero, J; Balint, B; Siebert, R; Taniguchi, H; Yamamoto, H; (2012) A DNA methylation fingerprint of 1628 human samples. GENOME RESEARCH , 22 (2) pp. 407-419. 10.1101/gr.119867.110.

Ferrer, IR; Liu, D; Pinelli, DF; Koehn, BH; Stempora, LL; Ford, ML; (2012) CD40/CD154 blockade inhibits dendritic cell expression of inflammatory cytokines but not costimulatory molecules. J Immunol , 189 (9) pp. 4387-4395. 10.4049/jimmunol.1201757.

Ferrer, IR; Wagener, ME; Song, M; Ford, ML; (2012) CD154 blockade alters innate immune cell recruitment and programs alloreactive CD8+ T cells into KLRG-1(high) short-lived effector T cells. PLoS One , 7 (7) , Article e40559. 10.1371/journal.pone.0040559.

Fielding, AK; Banerjee, L; Marks, DI; (2012) Recent Developments in the Management of T-Cell Precursor Acute Lymphoblastic Leukemia/Lymphoma. CURRENT HEMATOLOGIC MALIGNANCY REPORTS , 7 (2) pp. 160-169. 10.1007/s11899-012-0123-4.

Fields, P; Townsend, WM; Webb, A; Pocock, CFE; Smith, P; Kirkwood, A; El-Mehidi, N; (2012) First analysis of a phase II multicentre trial of rituximab, gemcitabine, cyclophosphamide, vincristine and prednisolone (R-GCVP) for patients with newly diagnosed diffuse large B cell lymphoma (DLBCL) considered unsuitable for anthracycline containing chemo-immunotherapy. An NCRI lymphoma clinical studies group trial. CRUK/07/007. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. pp. 13-14). WILEY-BLACKWELL

Fisher, R; Larkin, J; Swanton, C; (2012) Inter and intratumour heterogeneity: a barrier to individualized medical therapy in renal cell carcinoma? Front Oncol , 2 49-. 10.3389/fonc.2012.00049.

Fishman, J; Ansari, T; Sibbons, P; Lowdell, M; De Coppi, P; Birchall, M; (2012) Characterisation and immunogenicity of a decellularised skeletal muscle scaffold for laryngeal tissue engineering. In: (pp. p. 174). WILEY-BLACKWELL

Fizazi, K; Scher, HI; Molina, A; Logothetis, CJ; Chi, KN; Jones, RJ; Staffurth, JN; (2012) Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. LANCET ONCOLOGY , 13 (10) pp. 983-992. 10.1016/S1470-2045(12)70379-0.

Fleischhauer, K; Shaw, BE; Gooley, T; Malkki, M; Bardy, P; Bignon, JD; Dubois, V; (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: A retrospective study. The Lancet Oncology , 13 (4) pp. 366-374. 10.1016/S1470-2045(12)70004-9.

Fleischhauer, K; Shaw, BE; Gooley, T; Malkki, M; Bardy, P; Bignon, JD; Dubois, V; (2012) Effect of T-cell-epitope matching at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell transplantation: a retrospective study. Lancet Oncol , 13 (4) pp. 366-374. 10.1016/S1470-2045(12)70004-9.

Flicek, P; Amode, MR; Barrell, D; Beal, K; Brent, S; Carvalho-Silva, D; Clapham, P; (2012) Ensembl 2012. Nucleic Acids Res , 40 (Database) D84-D90. 10.1093/nar/gkr991.

Forshew, T; Murtaza, M; Parkinson, C; Gale, D; Tsui, DW; Kaper, F; Dawson, SJ; (2012) Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Sci Transl Med , 4 (136) 136ra68-. 10.1126/scitranslmed.3003726.

Forster, M; Mendes, R; Fedele, S; (2012) Synthetic Lethality and PARP-Inhibitors in Oral and Head & Neck Cancer. CURRENT PHARMACEUTICAL DESIGN , 18 (34) pp. 5431-5441.


Galandiuk, S; Rodriguez-Justo, M; Jeffery, R; Nicholson, AM; Cheng, Y; Oukrif, D; Elia, G; (2012) Field Cancerization in the Intestinal Epithelium of Patients With Crohn's Ileocolitis. GASTROENTEROLOGY , 142 (4) 855-U309. 10.1053/j.gastro.2011.12.004.

Gardiner, C; (2012) Guidelines for Evaluation of Coagulation Analyzer and Coagulation Testing, in Laboratory Hematology Practice. In: UNSPECIFIED Wiley-Blackwell

Gardiner, C; (2012) Guidelines for Evaluation of Coagulation Analyzers and Coagulation Testing. In: Laboratory Hematology Practice. (pp. 543-551).


Garelnabi, EAE; Pletsas, D; Li, L; Kiakos, K; Karodia, N; Hartley, JA; Phillips, RM; (2012) Strategy for Imidazotetrazine Prodrugs with Anticancer Activity Independent of MGMT and MMR. ACS MEDICINAL CHEMISTRY LETTERS , 3 (12) pp. 965-968. 10.1021/ml300132t.

Gerlinger, M; Rowan, AJ; Horswell, S; Larkin, J; Endesfelder, D; Gronroos, E; Martinez, P; (2012) Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing. NEW ENGLAND JOURNAL OF MEDICINE , 366 (10) pp. 883-892.

Gerlinger, M; Santos, CR; Spencer-Dene, B; Martinez, P; Endesfelder, D; Burrell, RA; Vetter, M; (2012) Genome-wide RNA interference analysis of renal carcinoma survival regulators identifies MCT4 as a Warburg effect metabolic target. JOURNAL OF PATHOLOGY , 227 (2) pp. 146-156. 10.1002/path.4006.

Germain, DP; Giugliani, R; Hughes, DA; Mehta, A; Nicholls, K; Barisoni, L; Jennette, CJ; (2012) Safety and pharmacodynamic effects of a pharmacological chaperone on alpha-galactosidase A activity and globotriaosylceramide clearance in Fabry disease: report from two phase 2 clinical studies. ORPHANET JOURNAL OF RARE DISEASES , 7 (ARTN 91) 10.1186/1750-1172-7-91. Gold open access

Gerrard, G; Mudge, K; Foskett, P; Stevens, D; Alikian, M; White, HE; Cross, NCP; (2012) Fast-mode duplex qPCR for BCR-ABL1 molecular monitoring: Innovation, automation, and harmonization. AMERICAN JOURNAL OF HEMATOLOGY , 87 (7) pp. 717-720. 10.1002/ajh.23212.

Gerrard, G; Valganon, M; Foong, HE; Kasperaviciute, D; Mueller, M; Game, L; Iskander, D; (2012) Target Enrichment and High-Throughput Sequencing of 80 Ribosomal Protein Genes to Identify Mutations Associated with Diamond-Blackfan Anaemia. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Ghorashian, S; Carpenter, B; Holler, A; Nicholson, E; Ahmadi, M; Zech, M; Bennett, C; (2012) CD4 Cells Engineered to Express an MHC Class I Restricted TCR Can Rescue CD8 Cells Tolerized to Tumour-Associated Antigens. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Ghorashian, S; Holler, A; Carpenter, B; Ahmadi, M; Nicholson, E; Zech, M; Xue, SA; (2012) CD4 cells expressing an MHC class I restricted TCR can rescue CD8 cells tolerized to tumour-associated antigen. In: (Proceedings) European Congress of Immunology. (pp. p. 707). WILEY-BLACKWELL

Ghorashian, S; Holler, A; Flutter, B; Xue, S-A; Fallah-Arani, F; Sivakumaran, J; Bennett, C; (2012) CD4 help can overcome tolerance developing in adoptively-transferred T cells transduced with a self-specific TCR. In: (Proceedings) Annual Conference of the British-Society-for-Gene-Therapy (BSGT). (pp. A6-A6). MARY ANN LIEBERT INC

Gibson, F; Fern, L; Whelan, J; Pearce, S; Lewis, IJ; Hobin, D; Taylor, RM; (2012) A scoping exercise of favourable characteristics of professionals working in teenage and young adult cancer care: 'thinking outside of the box'. EUROPEAN JOURNAL OF CANCER CARE , 21 (3) pp. 330-339. 10.1111/j.1365-2354.2011.01322.x.

Gibson, F; Shipway, L; Barry, A; Taylor, RM; (2012) What's It Like When You Find Eating Difficult Children's and Parents' Experiences of Food Intake. CANCER NURSING , 35 (4) pp. 265-277. 10.1097/NCC.0b013e31822cbd40.

Giest, S; McWhinnie, A; Lefranc, M-P; Little, A-M; Grace, S; Mackinnon, S; Madrigal, JA; (2012) Cytomegalovirus-specific CD8+T cells targeting different peptide/HLA combinations demonstrate varying T-cell receptor diversity. IMMUNOLOGY , 135 (1) pp. 27-39. 10.1111/j.1365-2567.2011.03508.x.

Giles, I; Khamashta, M; D'Cruz, D; Cohen, H; (2012) 'A new dawn of anticoagulation for patients with antiphospholipid syndrome?'. LUPUS , 21 (12) pp. 1263-1265. 10.1177/0961203312458843.

Gisselbrecht, C; Schmitz, N; Mounier, N; Gill, DS; Linch, DC; Trneny, M; Bosly, A; (2012) Rituximab Maintenance Therapy After Autologous Stem-Cell Transplantation in Patients With Relapsed CD20(+) Diffuse Large B-Cell Lymphoma: Final Analysis of the Collaborative Trial in Relapsed Aggressive Lymphoma. JOURNAL OF CLINICAL ONCOLOGY , 30 (36) pp. 4462-4469. 10.1200/JCO.2012.41.9416.

Glassford, J; Kassen, D; Quinn, J; Stengel, C; Kallinikou, K; Khwaja, A; Yong, KL; (2012) Inhibition of cell cycle progression by dual phosphatidylinositol-3-kinase and mTOR blockade in cyclin D2 positive multiple myeloma bearing IgH translocations. BLOOD CANCER JOURNAL , 2 (ARTN e50) 10.1038/bcj.2011.44. Gold open access

Goh, V; Engledow, A; Rodriguez-Justo, M; Shastry, M; Peck, J; Blackman, G; Endozo, R; (2012) The flow-metabolic phenotype of primary colorectal cancer: assessment by integrated 18F-FDG PET/perfusion CT with histopathologic correlation. J Nucl Med , 53 (5) pp. 687-692. 10.2967/jnumed.111.098525.

Goh, V; Rodriguez-Justo, M; Engledow, A; Shastry, M; Endozo, R; Peck, J; Meagher, M; (2012) Assessment of the metabolic flow phenotype of primary colorectal cancer: correlations with microvessel density are influenced by the histological scoring method. Eur Radiol , 22 (8) pp. 1687-1692. 10.1007/s00330-012-2423-4.

Goh, V; Shastry, M; Engledow, A; Kozarski, R; Peck, J; Endozo, R; Rodriguez-Justo, M; (2012) Integrated (18)F-FDG PET/CT and perfusion CT of primary colorectal cancer: effect of inter- and intraobserver agreement on metabolic-vascular parameters. AJR Am J Roentgenol , 199 (5) pp. 1003-1009. 10.2214/AJR.11.7823.

Goncalves, M; Walker-Samuel, S; Johnson, SP; Pedley, RB; Lythgoe, MF; (2012) Investigating Tumour Vascular Connectivity With MRI and Independent Component Analysis. In: (Proceedings) 22nd Biennial Congress of the European-Association-for-Cancer-Research. (pp. S205-S205). ELSEVIER SCI LTD

González-Beltrán, AN; Yong, MY; Dancey, G; Begent, R; (2012) Guidelines for information about therapy experiments: a proposal on best practice for recording experimental data on cancer therapy. BMC Res Notes , 5 10-. 10.1186/1756-0500-5-10. Gold open access

Goodeve, AC; Perry, DJ; Cumming, T; Hill, M; Jennings, I; Kitchen, S; Walker, I; (2012) Genetics of haemostasis. HAEMOPHILIA , 18 pp. 73-80. 10.1111/j.1365-2516.2012.02832.x.

Gooding, M; Tudzarova, S; Worthington, RJ; Kingsbury, SR; Rebstock, A-S; Dube, H; Simone, MI; (2012) Exploring the Interaction Between siRNA and the SMoC Biomolecule Transporters: Implications for Small Molecule-Mediated Delivery of siRNA. CHEMICAL BIOLOGY & DRUG DESIGN , 79 (1) pp. 9-21. 10.1111/j.1747-0285.2011.01249.x.

Goodwin, R; Giaccone, G; Calvert, H; Lobbezoo, M; Eisenhauer, EA; (2012) Targeted agents: How to select the winners in preclinical and early clinical studies? EUROPEAN JOURNAL OF CANCER , 48 (2) pp. 170-178. 10.1016/j.ejca.2011.09.024.

Grace, C; Nacheva, EP; (2012) Significance Analysis of Microarrays (SAM) Offers Clues to Differences Between the Genomes of Adult Philadelphia Positive ALL and the Lymphoid Blast Transformation of CML. Cancer Inform , 11 pp. 173-183. 10.4137/CIN.S9258. Gold open access

Greco, FA; Oien, K; Erlander, M; Osborne, R; Varadhachary, G; Bridgewater, J; Cohen, D; (2012) Cancer of unknown primary: progress in the search for improved and rapid diagnosis leading toward superior patient outcomes. ANNALS OF ONCOLOGY , 23 (2) pp. 298-304. 10.1093/annonc/mdr306.

Green, L; Lawrie, AS; Patel, R; Stephens, RCM; Mackie, IJ; Chitolie, A; Haddad, FS; (2012) The effect of total hip/knee replacement surgery and prophylactic dabigatran on thrombin generation and coagulation parameters. THROMBOSIS RESEARCH , 130 (5) pp. 775-779. 10.1016/j.thromres.2011.12.023.

Green, L; Safa, O; Machin, SJ; Mackie, IJ; Ryland, K; Cohen, H; Lawrie, AS; (2012) Development and application of an automated chromogenic thrombin generation assay that is sensitive to defects in the protein C pathway. THROMBOSIS RESEARCH , 130 (5) pp. 780-784. 10.1016/j.thromres.2011.12.034.

Griffin, J; Carpenter, B; Nicholson, E; Ghorasian, S; Holler, A; Velica, P; Xue, S; (2012) Gaining an advantage: mycophenolate-resistance for adoptively transferred cells. In: (Proceedings) European Congress of Immunology. (pp. p. 742). WILEY-BLACKWELL

Griffin, JE; Carpenter, B; Nicholson, E; Xue, S-A; Pule, M; Stauss, H; Chakraverty, R; (2012) In Vivo Selection of Mycophenolate Mofetil-Resistant T Cells for Adoptive Immunotherapy. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Guerra-Assunção, JA; Enright, AJ; (2012) Large-scale analysis of microRNA evolution. BMC Genomics , 13 218-. 10.1186/1471-2164-13-218.

Guerreiro, RJ; Lohmann, E; Kinsella, E; Bras, JM; Luu, N; Gurunlian, N; Dursun, B; (2012) Exome sequencing reveals an unexpected genetic cause of disease: NOTCH3 mutation in a Turkish family with Alzheimer's disease. NEUROBIOLOGY OF AGING , 33 (5) 10.1016/j.neurobiolaging.2011.10.009.

Guppy, NJ; El-Bahrawy, ME; Kocher, HM; Fritsch, K; Qureshi, YA; Poulsom, R; Jeffery, RE; (2012) Trefoil Factor Family Peptides in Normal and Diseased Human Pancreas. Pancreas , 41 (6) pp. 888-896. 10.1097/MPA.0b013e31823c9ec5.

Gurung, PMS; Williamson, M; West, C; Counsell, N; Ahmed, A; Benthani, F; Feber, A; (2012) The tumour suppressor gene, AIMP3 sensitises bladder cancer to chemo/radiotherapy in vitro and is a prognostic marker for overall survival in patients treated with radiotherapy for muscle invasive disease. EUROPEAN UROLOGY SUPPLEMENTS , 11 (1) E669-U430.


Hackshaw, A; (2012) The Benefits and Harms of Mammographic Screening for Breast Cancer: Building the Evidence Base Using Service Screening Programmes. Journal of Medical Screening , 19 (1_suppl) pp. 1-2. 10.1258/jms.2012.012074.

Hall, A; Germani, G; Isgro, G; Burroughs, AK; Dhillon, AP; (2012) Fibrosis distribution in explanted cirrhotic livers. HISTOPATHOLOGY , 60 (2) pp. 270-277. 10.1111/j.1365-2559.2011.04094.x.

Hall, PS; McCabe, C; Stein, RC; Cameron, D; (2012) Economic Evaluation of Genomic Test–Directed Chemotherapy for Early-Stage Lymph Node-Positive Breast Cancer. Journal of the National Cancer Institute , 104 (1) pp. 56-66. 10.1093/jnci/djr484.

Hammond, JA; Marsh, SGE; Robinson, J; Davies, CJ; Stear, MJ; Ellis, SA; (2012) Cattle MHC nomenclature: is it possible to assign sequences to discrete class I genes? IMMUNOGENETICS , 64 (6) pp. 475-480. 10.1007/s00251-012-0611-7.

Hardwick, N; Ledermann, JA; Aitkens, E; Chain, B; (2012) Pre-clinical assessment of autologous DC-based therapy in ovarian cancer patients with progressive disease. CANCER IMMUNOLOGY IMMUNOTHERAPY , 61 (11) pp. 1929-1939. 10.1007/s00262-012-1252-2.

Harrison, P; Gardiner, C; (2012) Invisible vesicles swarm within the iceberg. J Thromb Haemost , 10 (5) pp. 916-918. 10.1111/j.1538-7836.2012.04711.x.

Hartley, JA; Hamaguchi, A; Suggitt, M; Gregson, SJ; Thurston, DE; Howard, PW; (2012) DNA interstrand cross-linking and in vivo antitumor activity of the extended pyrrolo[2,1-c][1,4]benzodiazepine dimer SG2057. INVESTIGATIONAL NEW DRUGS , 30 (3) pp. 950-958. 10.1007/s10637-011-9647-z.

Hartley, JA; Hochhauser, D; (2012) Small molecule drugs - optimizing DNA damaging agent-based therapeutics. CURRENT OPINION IN PHARMACOLOGY , 12 (4) pp. 398-402. 10.1016/j.coph.2012.03.008.

He, M; Bakken, T; Kassimova, A; Boshoff, C; Philpott, N; Cannon, ML; (2012) Focal adhesion kinase is required for KSHV vGPCR signaling. MOLECULAR CARCINOGENESIS , 51 (4) pp. 339-351. 10.1002/mc.20790.

Helgason, GV; Allan, E; Galavotti, S; Audia, A; Hamilton, A; Mukhopadhyay, A; Karvela, M; (2012) Ponatinib and inhibition of the PI3K/Akt/mTOR pathway induces cell death and protective autophagy in TKI-resistant CML stem/progenitor cells. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. p. 1). WILEY-BLACKWELL

Helgason, GV; Allan, EK; Mariani, S; Mukhopadhyay, A; Karvela, M; Galavotti, S; Audia, A; (2012) Inhibition of Autophagy in Combination with Ponatinib or Dual PI3K/mTOR Inhibition to Improve Treatment Response for Both Bcr-Abl Dependent and Independent Mechanisms of TKI-Resistance in CML. In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Heneghan, C; Ward, A; Perera, R; Bankhead, C; Fuller, A; Stevens, S; Bradford, K; (2012) Self-monitoring of oral anticoagulation: systematic review and meta-analysis of individual patient data. The Lancet , 379 (9813) pp. 322-334. 10.1016/S0140-6736(11)61294-4. Green open access

Hergovich, A; (2012) Mammalian Hippo signalling: a kinase network regulated by protein-protein interactions. BIOCHEMICAL SOCIETY TRANSACTIONS , 40 pp. 124-128. 10.1042/BST20110619. Gold open access

Hergovich, A; (2012) YAP-Hippo signalling downstream of leukemia inhibitory factor receptor: implications for breast cancer. BREAST CANCER RESEARCH , 14 (6) 10.1186/bcr3349.

Hergovich, A; Hemmings, BA; (2012) Hippo signalling in the G2/M cell cycle phase: Lessons learned from the yeast MEN and SIN pathways. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY , 23 (7) pp. 794-802. 10.1016/j.semcdb.2012.04.001. Gold open access

Ho, KK; McGuire, VA; Koo, CY; Muir, KW; de Olano, N; Maifoshie, E; Kelly, DJ; (2012) Phosphorylation of FOXO3a on Ser-7 by p38 promotes its nuclear localization in response to doxorubicin. J Biol Chem , 287 (2) pp. 1545-1555. 10.1074/jbc.M111.284224.

Hockings, C; Peggs, K; (2012) Life after allogeneic bone marrow transplant. Br J Hosp Med (Lond) , 73 (6) C93-C96.

Holme, H; Hossain, U; Kirwan, M; Walne, A; Vulliamy, T; Dokal, I; (2012) Marked genetic heterogeneity in familial myelodysplasia/acute myeloid leukaemia. Br J Haematol , 158 (2) pp. 242-248. 10.1111/j.1365-2141.2012.09136.x.

Holme, H; Mun, KS; (2012) Postnatally diagnosed neonatal lupus. Arch Dis Child Fetal Neonatal Ed , 97 (2) F132-. 10.1136/archdischild-2011-301016.

Howie, AJ; Owen-Casey, MP; (2012) 'Apple-green birefringence' of amyloid stained by Congo red. KIDNEY INTERNATIONAL , 82 (1) p. 114. 10.1038/ki.2012.89.

Hu, M; Ayub, Q; Guerra-Assunção, JA; Long, Q; Ning, Z; Huang, N; Romero, IG; (2012) Exploration of signals of positive selection derived from genotype-based human genome scans using re-sequencing data. Hum Genet , 131 (5) pp. 665-674. 10.1007/s00439-011-1111-9.

Hughes, DA; Malmenas, M; Deegan, PB; Elliott, PM; Ginsberg, L; Hajioff, D; Ioannidis, AS; (2012) Fabry International Prognostic Index: a predictive severity score for Anderson-Fabry disease. JOURNAL OF MEDICAL GENETICS , 49 (3) pp. 212-220. 10.1136/jmedgenet-2011-100407.

Hytiroglou, P; Snover, DC; Alves, V; Balabaud, C; Bhathal, PS; Bioulac-Sage, P; Crawford, JM; (2012) Beyond "Cirrhosis" A Proposal From the International Liver Pathology Study Group. AMERICAN JOURNAL OF CLINICAL PATHOLOGY , 137 (1) pp. 5-9. 10.1309/AJCP2T2OHTAPBTMP.

Häsler, R; Feng, Z; Bäckdahl, L; Spehlmann, ME; Franke, A; Teschendorff, A; Rakyan, VK; (2012) A functional methylome map of ulcerative colitis. Genome Research , 22 (11) 2130 -2137. 10.1101/gr.138347.112. Green open access


Illingworth, C; Michael, AJ; (2012) Plant ornithine decarboxylase is not post-transcriptionally feedback regulated by polyamines but can interact with a cytosolic ribosomal protein S15 polypeptide. AMINO ACIDS , 42 (2-3) pp. 519-527. 10.1007/s00726-011-1029-5.

Iorns, E; Ward, TM; Dean, S; Jegg, A; Thomas, D; Murugaesu, N; Sims, D; (2012) Whole genome in vivo RNAi screening identifies the leukemia inhibitory factor receptor as a novel breast tumor suppressor. BREAST CANCER RESEARCH AND TREATMENT , 135 (1) pp. 79-91. 10.1007/s10549-012-2068-7.

Ip, L; Cia-Viciano, F; Spanswick, V; Pouigiannis, G; Cantley, L; Hartley, J; Hochhauser, D; (2012) Loss of the tumour suppressor inositol polyphosphate 4-phosphatase type II in ovarian cancer-implications for therapy. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE , 30 S19-S19.

Irshad, S; Grigoriadis, A; Lawler, K; Ng, T; Tutt, A; (2012) Profiling the immune stromal interface in breast cancer and its potential for clinical impact. Breast Care (Basel) , 7 (4) pp. 273-280. 10.1159/000341529.


Jamal-Hanjani, M; Spicer, J; (2012) Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer metastatic to the brain. Clin Cancer Res , 18 (4) pp. 938-944. 10.1158/1078-0432.CCR-11-2529.

Jenkinson, S; Koo, K; Goulden, N; Vora, A; Mitchell, C; Wade, R; Richards, SM; (2012) Presence of mutations in the NOTCH1 signalling pathway has a beneficial impact on outcome in paediatric T-ALL patients treated on the MRC UKALL2003 trial. In: (Proceedings) 52nd Annual Scientific Meeting of the British-Society-for-Haematology. (pp. pp. 19-20). WILEY-BLACKWELL

Jeyapalan, JN; Patel, SN; Forshew, T; Lawson, ARJ; Tatevossian, RG; Corbett-Jones, T; Mumin, MA; (2012) MICRORNA SIGNATURES IN A BROAD COHORT OF PAEDIATRIC BRAIN TUMOURS. In: (pp. p. 1084). WILEY PERIODICALS, INC

Jitlal, M; Khan, I; Lee, SM; Hackshaw, A; (2012) Stopping clinical trials early for futility: retrospective analysis of several randomised clinical studies. British Journal of Cancer , 107 (6) 910 - 917. 10.1038/bjc.2012.344. Green open access

Johnson, RJ; Davies, A; Lee, S-M; Gilson, D; Smith, P; Qian, W; Braganca, N; (2012) A Phase 1 Trial of Escalating High Dose Methotrexate Supported by Glucarpidase to Treat Patients with Primary Central Nervous System Lymphoma (PCNSL). (CRUK/08/010). In: (Proceedings) 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH). AMER SOC HEMATOLOGY

Johnson, SP; Laufer, JG; Zhang, EZ; Beard, PC; Pedley, RB; (2012) Determination of Differential Tumour Vascular Pathophysiology in Vivo by Photoacoustic Imaging. In: (Proceedings) 22nd Biennial Congress of the European-Association-for-Cancer-Research. (pp. S186-S187). ELSEVIER SCI LTD

Johnston, IG; Gaal, B; Neves, RP; Enver, T; Iborra, FJ; Jones, NS; (2012) Mitochondrial variability as a source of extrinsic cellular noise. PLoS Comput Biol , 8 (3) , Article e1002416. 10.1371/journal.pcbi.1002416. Green open access


Kallinikou, K; Anjos-Afonso, F; Blundell, MP; Ings, SJ; Watts, MJ; Thrasher, AJ; Linch, DC; (2012) Engraftment defect of cytokine-cultured adult human mobilized CD34(+) cells is related to reduced adhesion to bone marrow niche elements. BRITISH JOURNAL OF HAEMATOLOGY , 158 (6) pp. 778-787. 10.1111/j.1365-2141.2012.09219.x.

Kammertoens, T; Qin, Z; Briesemeister, D; Bendelac, A; Blankenstein, T; (2012) B-cells and IL-4 promote methylcholanthrene-induced carcinogenesis but there is no evidence for a role of T/NKT-cells and their effector molecules (Fas-ligand, TNF-α, perforin). Int J Cancer , 131 (7) pp. 1499-1508. 10.1002/ijc.27411.

Kanhere, A; Hertweck, A; Bhatia, U; Goekmen, MR; Perucha, E; Jackson, I; Lord, GM; (2012) T-bet and GATA3 orchestrate Th1 and Th2 differentiation through lineage-specific targeting of distal regulatory elements. NATURE COMMUNICATIONS , 3 (ARTN 126) 10.1038/ncomms2260.

Kanhere, A; Jenner, RG; (2012) Noncoding RNA localisation mechanisms in chromatin regulation. Silence , 3 (1) 2-. 10.1186/1758-907X-3-2. Gold open access

Karpathakis, A; Caplin, M; Thirlwell, C; (2012) Hitting the target: where do molecularly targeted therapies fit in the treatment scheduling of neuroendocrine tumours? ENDOCRINE-RELATED CANCER , 19 (3) R73-R92. 10.1530/ERC-12-0050.

Karwacz, K; Arce, F; Bricogne, C; Kochan, G; Escors, D; (2012) PD-L1 co-stimulation, ligand-induced TCR down-modulation and anti-tumor immunotherapy. ONCOIMMUNOLOGY , 1 (1) pp. 86-88. 10.4161/onci.1.1.17824.

Kashima, T; Halai, D; Ye, H; Hing, SN; Delaney, D; Pollock, R; O'Donnell, P; (2012) Sensitivity of MDM2 amplification and unexpected multiple faint alphoid 12 (alpha 12 satellite sequences) signals in atypical lipomatous tumor. MODERN PATHOLOGY , 25 (10) pp. 1384-1396. 10.1038/modpathol.2012.90.

Keeling, D; Mackie, I; Moore, GW; Greer, IA; Greaves, M; (2012) Guidelines on the investigation and management of antiphospholipid syndrome. BRITISH JOURNAL OF HAEMATOLOGY , 157 (1) pp. 47-58. 10.1111/j.1365-2141.2012.09037.x.

Keeling, D; Mackie, I; Moore, GW; Greer, IA; Greaves, M; (2012) Guidelines on the investigation and management of antiphospholipid syndrome. British Journal of Haematology , 157 (1) pp. 47-58. 10.1111/j.1365-2141.2012.09037.x.

Keeling, L; Suvarna, SK; Hughes, DA; (2012) Female Anderson-Fabry disease mimicking hypertrophic cardiomyopathy. JOURNAL OF CLINICAL PATHOLOGY , 65 (4) pp. 377-378. 10.1136/jclinpath-2011-200166.

Kelly, JD; Dudderidge, TJ; Wollenschlaeger, A; Okoturo, O; Burling, K; Tulloch, F; Halsall, I; (2012) Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22. PLOS One , 7 (7) , Article e40305. 10.1371/journal.pone.0040305. Green open access

Kepp, O; Menger, L; Vacchelli, E; Adjemian, S; Martins, I; Ma, Y; Sukkurwala, AQ; (2012) Anticancer activity of cardiac glycosides: At the frontier between cell-autonomous and immunological effects. Oncoimmunology , 1 (9) pp. 1640-1642. 10.4161/onci.21684.

Klionsky, DJ; Abdalla, FC; Abeliovich, H; Abraham, RT; Acevedo-Arozena, A; Adeli, K; Agholme, L; (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. AUTOPHAGY , 8 (4) pp. 445-544. 10.4161/auto.19496.

Knight, A; Mackinnon, S; Lowdell, MW; (2012) Human Vdelta1 gamma-delta T cells exert potent specific cytotoxicity against primary multiple myeloma cells. Cytotherapy , 14 (9) pp. 1110-1118. 10.3109/14653249.2012.700766.

Koo, BK; Spit, M; Jordens, I; Low, TY; Stange, DE; van de Wetering, M; van Es, JH; (2012) Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature , 488 (7413) pp. 665-669. 10.1038/nature11308.

Kwiatkowski, JL; Kim, H-Y; Thompson, AA; Quinn, CT; Mueller, BU; Odame, I; Giardina, PJ; (2012) Chelation use and iron burden in North American and British thalassemia patients: a report from the Thalassemia Longitudinal Cohort. BLOOD , 119 (12) pp. 2746-2753. 10.1182/blood-2011-04-344507.


Labit, H; Fujimitsu, K; Bayin, NS; Takaki, T; Gannon, J; Yamano, H; (2012) Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C. EMBO JOURNAL , 31 (15) pp. 3351-3362. 10.1038/emboj.2012.168.

Lafont, E; Dupont, R; Andrieu-Abadie, N; Okazaki, T; Schulze-Osthoff, K; Levade, T; Benoist, H; (2012) Ordering of ceramide formation and caspase-9 activation in CD95L-induced Jurkat leukemia T cell apoptosis. Biochim Biophys Acta , 1821 (4) pp. 684-693. 10.1016/j.bbalip.2012.01.012.

Lambertsen, KL; Anthony, DC; Couch, Y; Martin, NA; Ormhoj, M; Schmidt, M-LB; Deierborg, T; (2012) Anti-TNF therapy improves behavioural outcomes after focal cerebral ischemia in mice. In: (pp. p. 101).

Lanceley, A; Eagle, Z; Ogden, G; Gessler, S; Razvi, K; Ledermann, JA; Side, L; (2012) Family History and Women With Ovarian Cancer: Is it Asked and Does it Matter? An Observational Study. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER , 22 (2) pp. 254-259. 10.1097/IGC.0b013e3182392714.

Lanceley, A; Eagle, Z; Ogden, G; Gessler, S; Razvi, K; Ledermann, JA; Side, L; (2012) Family history and women with ovarian cancer: is it asked and does it matter?: An observational study. Int J Gynecol Cancer , 22 (2) pp. 254-259. 10.1097/IGC.0b013e3182392714.

Larkin, J; Goh, XY; Vetter, M; Pickering, L; Swanton, C; (2012) Epigenetic regulation in RCC: opportunities for therapeutic intervention? Nat Rev Urol , 9 (3) pp. 147-155. 10.1038/nrurol.2011.236.

Last, V; Williams, A; Werling, D; (2012) Inhibition of cytosolic Phospholipase A(2) prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin. BMC NEUROSCIENCE , 13 (ARTN 106) 10.1186/1471-2202-13-106. Gold open access

Laufer, J; Jathoul, A; Johnson, P; Zhang, E; Lythgoe, M; Pedley, RB; Pule, M; (2012) In vivo photoacoustic imaging of tyrosinase expressing tumours in mice. PHOTONS PLUS ULTRASOUND: IMAGING AND SENSING 2012 , 8223 (ARTN 822) 10.1117/12.907006.

Laufer, J; Johnson, P; Zhang, E; Treeby, B; Cox, B; Pedley, B; Beard, P; (2012) In vivo preclinical photoacoustic imaging of tumor vasculature development and therapy. JOURNAL OF BIOMEDICAL OPTICS , 17 (5) 10.1117/1.JBO.17.5.056016.

Lawrie, AS; Hills, J; Longair, I; Green, L; Gardiner, C; MacHin, SJ; Cohen, H; (2012) The clinical significance of differences between point-of-care and laboratory INR methods in over-anticoagulated patients. Thrombosis Research , 130 (1) pp. 110-114. 10.1016/j.thromres.2011.08.027.

Lawrie, AS; Hills, J; Longair, I; Green, L; Gardiner, C; Machin, SJ; Cohen, H; (2012) The clinical significance of differences between point-of-care and laboratory INR methods in over-anticoagulated patients. THROMBOSIS RESEARCH , 130 (1) pp. 110-114. 10.1016/j.thromres.2011.08.027.

Lawrie, AS; Pizzey, A; Trompeter, S; Meiselman, H; Mohandas, N; Dumanski, JP; Westerman, MP; (2012) Procoagulant activity in patients with sickle cell trait. BLOOD COAGULATION & FIBRINOLYSIS , 23 (4) pp. 268-270. 10.1097/MBC.0b013e32835187f8.

Lechner, M; (2012) Genomic and Epigenomic Analysis of HPV positive and HPV negative Head and Neck Squamous Cell Cancer. Doctoral thesis, UCL (University College London). Green open access

Ledermann, J; Harter, P; Gourley, C; Friedlander, M; Vergote, I; Rustin, G; Scott, C; (2012) Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer. NEW ENGLAND JOURNAL OF MEDICINE , 366 (15) pp. 1382-1392. 10.1056/NEJMoa1105535.

Lee, AJX; Roylance, R; Sander, J; Gorman, P; Endesfelder, D; Kschischo, M; Jones, NP; (2012) CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction. JOURNAL OF PATHOLOGY , 226 (3) pp. 482-494. 10.1002/path.2998.

Lee, AJX; Swanton, C; (2012) Tumour heterogeneity and drug resistance: Personalising cancer medicine through functional genomics. BIOCHEMICAL PHARMACOLOGY , 83 (8) pp. 1013-1020. 10.1016/j.bcp.2011.12.008.

Lee, M; Satam, V; Babu, B; Gregory, M; Bowerman, M; Savagian, M; Lee, M; (2012) Complete analysis on the two base pair sequence recognition by Hx (p-anisylbenzimidazole)center dot pyrrole and Hx center dot imidazole pairings. In: (Proceedings) 244th National Fall Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC

Lee, M; Satam, V; Babu, B; Porte, A; Savagian, M; Lee, MD; Liu, Y; (2012) Synthesis and DNA binding properties of 1-(3-aminopropyl)imidazole-containing triamide f-Im*PyIm: a novel diamino polyamide designed to target 5 '-ACGCGT-3 '. In: (Proceedings) 244th National Fall Meeting of the American-Chemical-Society (ACS). AMER CHEMICAL SOC


Lee, SM; Khan, I; Upadhyay, S; Lewanski, C; Falk, S; Skailes, G; Marshall, E; (2012) First-line erlotinib in patients with advanced non-small-cell lung cancer unsuitable for chemotherapy (TOPICAL): a double-blind, placebo-controlled, phase 3 trial. LANCET ONCOLOGY , 13 (11) pp. 1161-1170. 10.1016/S1470-2045(12)70412-6. Gold open access

Lemech, C; Arkenau, HT; (2012) Novel treatments for metastatic cutaneous melanoma and the management of emergent toxicities. Clin Med Insights Oncol , 6 pp. 53-66. 10.4137/CMO.S5855. Gold open access

Lemech, C; Infante, J; Arkenau, H-T; (2012) The potential for BRAF V600 inhibitors in advanced cutaneous melanoma: rationale and latest evidence. THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY , 4 (2) pp. 61-73. 10.1177/1758834011432949. Gold open access

Li, M; Wu, H; Luo, Z; Xia, Y; Guan, J; Wang, T; Gu, Y; (2012) An atlas of DNA methylomes in porcine adipose and muscle tissues. NATURE COMMUNICATIONS , 3 (ARTN 850) 10.1038/ncomms1854.

Lobo, C; Amin, S; Ramsay, A; Diss, T; Kocjan, G; (2012) Serous fluid cytology of multicentric Castleman's disease and other lymphoproliferative disorders associated with Kaposi sarcoma-associated herpes virus: a review with case reports. CYTOPATHOLOGY , 23 (2) pp. 76-85. 10.1111/j.1365-2303.2011.00868.x.

Lombardo, CM; Welsh, SJ; Strauss, SJ; Dale, AG; Todd, AK; Nanjunda, R; Wilson, WD; (2012) A novel series of G-quadruplex ligands with selectivity for HIF-expressing osteosarcoma and renal cancer cell lines. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS , 22 (18) pp. 5984-5988. 10.1016/j.bmcl.2012.07.009.

Loosemore, M; Walsh, SB; Morris, E; Stewart, G; Porter, JB; Montgomery, H; (2012) Sudden exertional death in sickle cell trait. BRITISH JOURNAL OF SPORTS MEDICINE , 46 (5) pp. 312-314. 10.1136/bjsports-2011-090521.

Lotta, LA; Wu, HM; Mackie, IJ; Noris, M; Veyradier, A; Scully, MA; Remuzzi, G; (2012) Residual plasmatic activity of ADAMTS13 is correlated with phenotype severity in congenital thrombotic thrombocytopenic purpura. BLOOD , 120 (2) pp. 440-448. 10.1182/blood-2012-01-403113.