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Number of items: 80.


Abraham, DJ; Xu, SW; Black, CM; Sa, S; Xu, YL; Leask, A; (2000) Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts. J BIOL CHEM , 275 (20) 15220 - 15225. Gold open access

Abrahams, VM; Cambridge, G; Lydyard, PM; Edwards, JCW; (2000) Induction of tumor necrosis factor alpha production by adhered human monocytes - A key role for Fc gamma receptor type IIIA in rheumatoid arthritis. ARTHRITIS AND RHEUMATISM , 43 (3) pp. 608-616. 10.1002/1529-0131(200003)43:3<608::AID-ANR18>3.0.CO;2-G.


Bellotti, V; Mangione, P; Merlini, G; (2000) Review: immunoglobulin light chain amyloidosis--the archetype of structural and pathogenic variability. J Struct Biol , 130 (2-3) pp. 280-289. 10.1006/jsbi.2000.4248.

Bollard, M; Caldwell, J; Taylor, GW; Strolin-Benedetti, M; Semeraro, C; (2000) Pharmacokinetics and disposition of the novel dopamine agonist Z-7760 in rat after intravenous and oral administration. Xenobiotica , 30 (10) pp. 983-991. 10.1080/00498250050200131.

Booth, DR; Gillmore, JD; Lachmann, HJ; Booth, SE; Bybee, A; Soyturk, M; Akar, S; ... Hawkins, PN; + view all (2000) The genetic basis of autosomal dominant familial Mediterranean fever. QJM-INT J MED , 93 (4) 217 - 221.

Booth, DR; Pepys, MB; Hawkins, PN; (2000) A novel variant of human lysozyme (T70N) is common in the normal population. Hum Mutat , 16 (2) 180-. 10.1002/1098-1004(200008)16:2<180::AID-HUMU20>3.0.CO;2-#.

Booth, DR; Stangou, A; Williams, RS; Gillmore, JD; Tennent, GA; Hawkins, PN; (2000) Transthyretin Ile84Thr is associated with familial amyloid polyneuropathy. Hum Mutat , 16 (5) 447-. 10.1002/1098-1004(200011)16:5<447::AID-HUMU16>3.0.CO;2-P.


Coker, AR; Purvis, A; Baker, D; Pepys, MB; Wood, SP; (2000) Molecular chaperone properties of serum amyloid P component. FEBS LETT , 473 (2) 199 - 202.


Danesh, J; Pepys, MB; (2000) C-reactive protein in healthy and in sick populations. EUR HEART J , 21 (19) 1564 - 1565. 10.1053/euhj.2000.2229.

Danesh, J; Whincup, P; Walker, M; Lennon, L; Thomson, A; Appleby, P; Gallimore, JR; (2000) Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. BRIT MED J , 321 (7255) 199 - 204.

De Lorenzi, E; Galbusera, C; Bellotti, V; Mangione, P; Massolini, G; Tabolotti, E; Andreola, A; (2000) Affinity capillary electrophoresis is a powerful tool to identify transthyretin binding drugs for potential therapeutic use in amyloidosis. Electrophoresis , 21 (15) pp. 3280-3289. 10.1002/1522-2683(20000901)21:15<3280::AID-ELPS3280>3.0.CO;2-L.

Dean, GS; Tyrrell-Price, J; Crawley, E; Isenberg, DA; (2000) Cytokines and systemic lupus erythematosus. ANN RHEUM DIS , 59 (4) 243 - 251.

Denton, CP; Black, CM; (2000) Scleroderma and related disorders: therapeutic aspects. BEST PRACT RES CL RH , 14 (1) 17 - 35.

Denton, CP; Howell, K; Stratton, RJ; Black, CM; (2000) Long-term low molecular weight heparin therapy for severe Raynaud's phenomenon: A pilot study. CLIN EXP RHEUMATOL , 18 (4) 499 - 502.


Eftekhari, P; Salle, L; Lezoualc'h, F; Mialet, J; Gastineau, M; Briand, JP; Isenberg, DA; ... Hoebeke, J; + view all (2000) Anti-SSA/Ro52 autoantibodies blocking the cardiac 5-HT4 serotoninergic receptor could explain neonatal lupus congenital heart block. EUR J IMMUNOL , 30 (10) 2782 - 2790.

Ehrenstein, MR; Cook, HT; Neuberger, MS; (2000) Deficiency in serum immunoglobulin (Ig)M predisposes to development of IgG autoantibodies. J EXP MED , 191 (7) 1253 - 1257.

Eilliott, PM; Mahon, NG; Matsumura, Y; Hawkins, PN; Gillmore, JD; McKenna, WJ; (2000) Tissue Doppler features of cardiac amyloidosis. CLIN CARDIOL , 23 (9) 701 - 701.

Ellmerich, S; Djouder, N; Scholler, M; Klein, JP; (2000) Production of cytokines by monocytes, epithelial and endothelial cells activated by Streptococcus bovis. CYTOKINE , 12 (1) 26 - 31.

Ellmerich, S; Scholler, M; Duranton, B; Gosse, F; Galluser, M; Klein, JP; Raul, F; (2000) Promotion of intestinal carcinogenesis by Streptococcus bovis. CARCINOGENESIS , 21 (4) 753 - 756.

Esposito, G; Michelutti, R; Verdone, G; Viglino, P; Hernández, H; Robinson, CV; Amoresano, A; ... Bellotti, V; + view all (2000) Removal of the N-terminal hexapeptide from human beta2-microglobulin facilitates protein aggregation and fibril formation. Protein Sci , 9 (5) pp. 831-845. 10.1110/ps.9.5.831.

Ezeonyeji, A; Jewitt, S; Poyser, L; Stadward, T; (2000) Babies sleeping with parents and sudden infant death syndrome. Smoking may be residual confounder in bed sharing. BMJ , 321 (7267) pp. 1019-1020.


Frampton, G; Moriya, S; Pearson, JD; Isenberg, DA; Ward, FJ; Smith, TA; Panayiotou, A; ... Murphy, JJ; + view all (2000) Identification of candidate endothelial cell autoantigens in systemic lupus erythematosus using a molecular cloning strategy: a role for ribosomal P protein P0 as an endothelial cell autoantigen. RHEUMATOLOGY , 39 (10) 1114 - 1120.

Fröhlich, M; Imhof, A; Berg, G; Hutchinson, WL; Pepys, MB; Boeing, H; Muche, R; ... Koenig, W; + view all (2000) Association between C-reactive protein and features of the metabolic syndrome. Diabetes Care , 23 (12) pp. 1835-1839. 10.2337/diacare.23.12.1835.

Fröhlich, M; Imhof, A; Berg, G; Hutchinson, WL; Pepys, MB; Boeing, H; Muche, R; ... Koenig, W; + view all (2000) Association between C-reactive protein and features of the metabolic syndrome: a population-based study. Diabetes Care , 23 (12) pp. 1835-1839. 10.2337/diacare.23.12.1835.


Gao, B; Abraham, D; Black, CM; Jacobs, M; Bruckdorfer, KR; (2000) Effects of nitric oxide and peroxynitrite on collagen biosynthesis by normal and scleroderma skin fibroblasts. Nitric Oxide , 4 (3) pp. 287-288.

Giles, I; Isenberg, D; (2000) Fatigue in primary Sjogren's syndrome: Is there a link with the fibromyalgia syndrome? ANNALS OF THE RHEUMATIC DISEASES , 59 (11) pp. 875-878. 10.1136/ard.59.11.875.

Giles, I; Isenberg, DA; (2000) Sjogren`s patients with fatigue: is there a link with the Fibromyalgia syndrome? Annals of the Rheumatic Diseases , 59 (11) pp. 875-878.

Gillmore, JD; Booth, DR; Rela, M; Heaton, ND; Rahman, V; Stangou, AJ; Pepys, MB; (2000) Curative hepatorenal transplantation in systemic amyloidosis caused by the Glu526Val fibrinogen alpha-chain variant in an English family. QJM-INT J MED , 93 (5) 269 - 275.

Gillmore, JD; Madhoo, S; Pepys, MB; Hawkins, PN; (2000) Renal transplantation for amyloid end-stage renal failure-insights from serial serum amyloid P component scintigraphy. NUCL MED COMMUN , 21 (8) 735 - 740.

Gladman, DD; Goldsmith, CH; Urowitz, MB; Bacon, P; Fortin, P; Ginzler, E; Gordon, C; ... Systemic Lupus Int Collaborating C, ; + view all (2000) The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) Damage Index for systemic lupus erythematosus international comparison. J RHEUMATOL , 27 (2) 373 - 376.


Harada, H; Chan, CM; Loesch, A; Unwin, R; Burnstock, G; (2000) Induction of proliferation and apoptotic cell death via P2Y and P2X receptors, respectively, in rat glomerular mesangial cells. KIDNEY INT , 57 (3) 949 - 958.

Hasserjian, RP; Lachmann, HJ; Gillmore, JD; Hawkins, PM; (2000) Correlation of bone marrow findings with organ distribution and amyloid burden in 103 patients with al amyloidosis. Blood , 96 (11 PART )

Hasserjian, RP; Lachmann, HJ; Gillmore, JD; Hawkins, PN; (2000) Correlation of bone marrow findings with organ distribution and amyloid burden in 103 patients with AL amyloidosis. BLOOD , 96 (11) 157A - 157A.

Hutchinson, WL; Hohenester, E; Pepys, MB; (2000) Human serum amyloid P component is a single uncomplexed pentamer in whole serum. MOL MED , 6 (6) 482 - 493. Gold open access

Hutchinson, WL; Koenig, W; Frohlich, M; Sund, M; Lowe, GDO; Pepys, MB; (2000) Immunoradiometric assay of circulating C-reactive protein: age-related values in the adult general population. CLIN CHEM , 46 (7) 934 - 938.


Ioannou, Y; Isenberg, DA; (2000) Current evidence for the induction of autoimmune rheumatic manifestations by cytokine therapy. ARTHRITIS RHEUM , 43 (7) 1431 - 1442.

Isenberg, DA; (2000) Lupus-molecular and cellular pathogenesis. Ann Rheum Dis , 59 (3) 172A-1172. 10.1136/ard.59.3.172a.

Isenberg, DA; Gordon, C; BILAG Grp, ; (2000) From BILAG to BLIPS - disease activity assessment in lupus past, present and future. LUPUS , 9 (9) 651 - 654.


Kumar, S; Kalsi, J; Ravirajan, CT; Rahman, A; Athwal, D; Latchman, DS; Isenberg, DA; (2000) Molecular cloning and expression of the fabs of human autoantibodies in Escherichia coli - Determination of the heavy or light chain contribution to the anti-DNA/-cardiolipin activity of the Fab. J BIOL CHEM , 275 (45) 35129 - 35136. Gold open access


Lachmann, HJ; Booth, DR; Bybee, A; Hawkins, PN; (2000) Transthyretin Ala97Ser is associated with familial amyloidotic polyneuropathy in a Chinese-Taiwanese family. Hum Mutat , 16 (2) 180-. 10.1002/1098-1004(200008)16:2<180::AID-HUMU19>3.0.CO;2-A.

Loesch, A; Burnstock, G; (2000) Ultrastructural localisation of ATP-gated P2X(2) receptor immunoreactivity in vascular endothelial cells in rat brain. ENDOTHELIUM-JOURNAL OF ENDOTHELIAL CELL RESEARCH , 7 (2) pp. 93-98. 10.3109/10623320009072204.

Loesch, A; Burnstock, G; (2000) Ultrastructural localization of arginine vasopressin in coronary vessels of newborn rat. CELL AND TISSUE RESEARCH , 299 (3) pp. 403-408.

Loesch, A; Miah, S; Burnstock, G; (2000) Electron-immunoreactivity for P2X<sub>2</sub> receptors in the rat neurosecretory system. In: (pp. 82-).

Lydyard, PM; Youinou, PY; Isenberg, DA; (2000) Apoptosis and autoimmune diseases. In: Ruffolo, RR and Walsh, F, (eds.) Apoptosis in health and disease. (pp. 17-31). Harwood Academic Publishers


Marinova-Mutafchieva, L; Williams, RO; Mauri, C; Mason, LJ; Walmsley, MJ; Taylor, PC; Feldmann, M; (2000) A comparative study into the mechanisms of action of anti-tumor necrosis factor alpha, anti-CD4, and combined anti-tumor necrosis factor alpha/anti-CD4 treatment in early collagen-induced arthritis. ARTHRITIS RHEUM , 43 (3) 638 - 644.

Massa, M; Mangione, P; Pignatti, P; Stoppini, M; Zanotti, G; Arcidiaco, P; Merlini, G; ... Bellotti*, V; + view all (2000) Conformational dynamics of the β2-microglobulin C terminal in the cell-membrane-anchored major histocompatibility complex type I. Cellular and Molecular Life Sciences , 57 (4) pp. 675-683. 10.1007/PL00000727.

Mauri, C; Mars, LT; Londei, M; (2000) Therapeutic activity of agonistic anti-CD40 mAb in a chronic autoimmune inflammatory process. FASEB J , 14 (6) A1101 - A1101.

Mauri, C; Mars, LT; Londei, M; (2000) Therapeutic activity of agonistic monoclonal antibodies against CD40 in a chronic autoimmune inflammatory process. NAT MED , 6 (6) 673 - 679.

McDermott, MF; Aganna, E; Hitman, GA; Ogunkolade, BW; Booth, DR; Hawkins, PN; (2000) An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q (vol 43, pg 2034, 2000). ARTHRITIS AND RHEUMATISM , 43 (10) p. 2379.

McDermott, MF; Aganna, E; Hitman, GA; Ogunkolade, BW; Booth, DR; Hawkins, PN; (2000) An autosomal dominant periodic fever associated with AA amyloidosis in a north Indian family maps to distal chromosome 1q. ARTHRITIS AND RHEUMATISM , 43 (9) pp. 2034-2040. 10.1002/1529-0131(200009)43:9<2034::AID-ANR14>3.0.CO;2-J.

McDonagh, JE; Isenberg, DA; (2000) Development of additional autoimmune diseases in a population of patients with systemic lupus erythematosus. ANN RHEUM DIS , 59 (3) 230 - 232.

Milner, P; Loesch, A; Burnstock, G; (2000) Endothelin immunoreactivity and mRNA expression in sensory and sympathetic neurones following selective denervation. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE , 18 (8) pp. 727-734. 10.1016/S0736-5748(00)00054-X.

Milner, P; Loesch, A; Burnstock, G; (2000) Endothelin immunoreactivity and mRNA expression in sensory and sympathetic neurons following selective denervation. In: (pp. 48-).

Milner, P; Loesch, A; Burnstock, G; (2000) Neural endothelin in hypertension: Increased expression in ganglia and nerves to cerebral arteries of the spontaneously hypertensive rat. JOURNAL OF VASCULAR RESEARCH , 37 (1) pp. 39-49. 10.1159/000025712.

Mok, MY; Farewell, VT; Isenberg, DA; (2000) Risk factors for avascular necrosis of bone in patients with systemic lupus erythematosus: Is there a role for antiphospholipid antibodies? ANN RHEUM DIS , 59 (6) 462 - 467.

Moore, AD; Petri, MA; Manzi, S; Isenberg, DA; Gordon, C; Senécal, JL; St Pierre, Y; ... Clarke, AE; + view all (2000) The use of alternative medical therapies in patients with systemic lupus erythematosus. Trination Study Group. Arthritis Rheum , 43 (6) pp. 1410-1418. 10.1002/1529-0131(200006)43:6<1410::AID-ANR27>3.0.CO;2-U.

Mumford, AD; O'Donnell, J; Gillmore, JD; Manning, RA; Hawkins, PN; Laffan, M; (2000) Bleeding symptoms and coagulation abnormalities in 337 patients with AL-amyloidosis. BRIT J HAEMATOL , 110 (2) 454 - 460.

Murray, S; Bliss, P; Karim, N; Calam, J; Taylor, GW; (2000) Analysis of N(alpha)-methylhistamine by gas chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl , 739 (2) pp. 337-344.

Murray, S; Taylor, GW; Karim, QN; Bliss, P; Calam, J; (2000) N alpha-methylhistamine: association with Helicobacter pylori infection in humans and effects on gastric acid secretion. Clin Chim Acta , 301 (1-2) pp. 181-192. 10.1016/s0009-8981(00)00357-0.


Neuberger, MS; Ehrenstein, MR; Rada, C; Sale, J; Batista, FD; Williams, G; Milstein, C; (2000) Memory in the B-cell compartment: antibody affinity maturation. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES B-BIOLOGICAL SCIENCES , 355 (1395) 357 - 360.

Neuberger, MS; Sale, JE; Cumbers, SJ; Jolly, CJ; Bemark, MP; Ehrenstein, MR; Lanoue, A; ... Williams, GT; + view all (2000) Diversification and selection mechanisms for the production of protein repertoires - Lessons from the immune system. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY , 83 (1-3) 53 - 60.

Noursadeghi, M; Bickerstaff, MCM; Gallimore, JR; Herbert, J; Cohen, J; Pepys, MB; (2000) Role of serum amyloid P component in bacterial infection: Protection of the host or protection of the pathogen. P NATL ACAD SCI USA , 97 (26) 14584 - 14589.


Palha, JA; Ballinari, D; Amboldi, N; Cardoso, I; Fernandes, R; Bellotti, V; Merlini, G; (2000) 4'-Iodo-4'-deoxydoxorubicin disrupts the fibrillar structure of transthyretin amyloid. Am J Pathol , 156 (6) pp. 1919-1925. 10.1016/S0002-9440(10)65065-1.

Perraudeau, M; Taylor, PR; Stauss, HJ; Lindstedt, R; Bygrave, AE; Pappin, DJC; Ellmerich, S; ... Altmann, DM; + view all (2000) Altered major histocompatibility complex class II peptide loading in H2-O-deficient mice. EUR J IMMUNOL , 30 (10) 2871 - 2880.

Pittoni, V; Ravirajan, CT; Donohoe, S; Machin, SJ; Lydyard, PM; Isenberg, DA; (2000) Human monoclonal anti-phospholipid antibodies selectively bind to membrane phospholipid and beta(2)-glycoprotein I (beta(2)-GPI) on apoptotic cells. CLIN EXP IMMUNOL , 119 (3) 533 - 543.


Radway-Bright, EL; Ravirajan, CT; Isenberg, DA; (2000) The prevalence of antibodies to anionic phospholipids in patients with the primary antiphospholipid syndrome, systemic lupus erythematosus and their relatives and spouses. RHEUMATOLOGY , 39 (4) 427 - 431.

Ramafi, G; Anderson, R; Theron, AJ; Feldman, C; Taylor, GW; Wilson, R; Cole, PJ; (2000) CGS 21680, dibutyryl cyclic AMP and rolipram attenuate the pro-inflammatory interactions of the Pseudomonas aeruginosa -derived pigment, 1-hydroxyphenazine, with human neutrophils. Pulm Pharmacol Ther , 13 (6) pp. 293-299. 10.1006/pupt.2000.0257.


Serpell, LC; Sunde, M; Benson, MD; Tennent, GA; Pepys, MB; Fraser, PE; (2000) The protofilament substructure of amyloid fibrils. J MOL BIOL , 300 (5) 1033 - 1039. 10.1006/jmbi.2000.3908.

Shi-Wen, X; Pennington, D; Holmes, A; Leask, A; Bradham, D; Beauchamp, JR; Fonseca, C; ... Abraham, DJ; + view all (2000) Autocrine overexpression of CTGF maintains fibrosis: RDA analysis of fibrosis genes in systemic sclerosis. EXP CELL RES , 259 (1) 213 - 224. 10.1006/excr.2000.4972.

Stangou, AJ; Lachmann, H; O'Grady, JG; Alexander, G; Millson, CE; Pepys, MB; Hawkins, PN; (2000) Liver transplantation for end stage hepatic amyloidosis. In: (pp. S139-S139). LIPPINCOTT WILLIAMS & WILKINS

Stangou, AJ; Lachmann, H; OʼGrady, JG; Alexander, G; Millson, CE; Pepys, MB; Hawkins, PN; (2000) LIVER TRANSPLANTATION FOR END STAGE HEPATIC AMYLOIDOSIS. Transplantation , 69 (Suppleme) S139-S139. 10.1097/00007890-200004271-00105.

Stoll, T; Sutcliffe, N; Klaghofer, R; Isenberg, DA; (2000) Do present damage and health perception in patients with systemic lupus erythematosus predict extent of future damage? a prospective study. ANN RHEUM DIS , 59 (10) 832 - 835.

Stoppini, MS; Arcidiaco, P; Mangione, P; Giorgetti, S; Brancaccio, D; Bellotti, V; (2000) Detection of fragments of beta2-microglobulin in amyloid fibrils. Kidney Int , 57 (1) pp. 349-350. 10.1046/j.1523-1755.2000.00851.x.

Sultan, SM; Ioannou, Y; Isenberg, DA; (2000) Is there an association of malignancy with systemic lupus erythematosus? An analysis of 276 patients under long-term review. RHEUMATOLOGY , 39 (10) 1147 - 1152.

Sutcliffe, N; Smith, C; Speight, PM; Isenberg, DA; (2000) Mucosa-associated lymphoid tissue lymphomas in two patients with rheumatoid arthritis on second-line agents, and secondary Sjogren's syndrome. RHEUMATOLOGY , 39 (2) 185 - 188.


Tench, CM; Isenberg, DA; (2000) The variation in anti-ENA characteristics between different ethnic populations with systemic lupus erythematosus over a 10-year period. LUPUS , 9 (5) 374 - 376.


Wechalekar, A; Ganczakowski, M; Cranfield, TG; Sinclair, D; Prentice, HG; Goldman, JM; Bell, AJ; (2000) Ccurrence of autoantibodies in patients developing graft versus hostdkease after allogeneicbone marrow transplant. Blood , 96 (11 PART )

Wechalekar, A; Ganczakowski, M; Cranfield, TG; Sinclair, D; Prentice, HG; Goldman, JM; Bell, AJ; (2000) Occurrence of autoantibodies in patients developing graft versus host disease after allogeneic bone marrow transplant. BLOOD , 96 (11) 198A - 198A.

Wechalekar, A; Parapia, L; (2000) Hereditary haemorrhagic telangiectasia with protein S deficiency in a family: a case report. EUR J HAEMATOL , 64 (1) 59 - 60.


Yang, X; Davie, N; Upton, PD; Taylor, GW; Wharton, J; Morrell, NW; (2000) Stimulation and inhibition of distal pulmonary artery smooth muscle cell growth by hypoxia. Thorax , 55 (SUPPL. 3)

This list was generated on Sun Sep 8 06:58:52 2019 BST.