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Number of items: 96.

A

Al-Marzouqi, I.; (2006) Recovery and purification of plasmid DNA gene therapy vectors using aqueous two-phase systems in a J-type countercurrent chromatograph. Doctoral thesis, University of London. Green open access
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Arulmuthu, ER; Versteeg, HK; Baldiscini, H; Khoo, YC; Hoare, M; Williams, DJ; (2006) Plasmid DNA damage in a mesh debuliser – an initial high-speed imaging study. Proc. Respiratory Drug Delivery (3) pp. 671-674.

B

Baldwin, CVF; Woodley, JM; (2006) On oxygen limitation in a whole-cell biocatalytic Baeyer-Villiger oxidation process. Biotechnology and Bioengineering

Batagov, A; Baganz, F; (2006) Metabolome profiling of E. coli by capillary electrophoresis using novel techniques of multi-wavelength spectral analysis and data mining. Presented at: 7th International Conference on Systems Biology.

Betts, JI; Doig, SD; Baganz, F; (2006) Characterization and application of a miniature 10 mL stirred-tank bioreactor, showing scale-down equivalence with a conventional 7 L reactor. BIOTECHNOL PROGR , 22 (3) 681 - 688. 10.1021/bp050369y.

Biddlecombe, J; Craig, A; Zhang, H; Uddin, S; Mulot, S; Fish, B; Titchener-Hooker, N; (2006) Mimicking interfacial effects in bioprocessing of monoclonal antibodies. In: (Proceedings) UCL IMRC Briefing. : London, UK.

Bracewell, DG; (2006) Multi-step microscale chromatography to rapidly evaluate fermentation performance in the optimisation of HPV virus-like particle expression. Presented at: Vaccines, Quality control, scale-up and manufacture.

Bracewell, DG; Sorensen, E; Titchener-Hooker, N; (2006) BIOT 416-Integration of experimental and modeling approaches to extend the utility of bioprocess chromatography simulation. In: ABSTR PAP AM CHEM S. (pp. ? - ?). AMER CHEMICAL SOC

Branston, SD; Stanley, EC; Keshavarz-Moore, E; Ward, JM; (2006) The pharmaceutical processing of genetically engineered bacteriophage. Presented at: Phage Technologies Workshop.

C

Chen, BH; Micheletti, M; Sayar, A; Dalby, PA; Baganz, F; Lye, GJ; Woodley, M; (2006) Biocatalytic process evaluation using microscale processing techniques and process modelling. In: (Proceedings) European Symposium on Biochemical Engineering Science (ESBES06. : Salzburg, Austria.

Chen, BH; Sayar, A; Kaulmann, U; Dalby, PA; Ward, JM; Woodley, JM; (2006) Reaction modelling and simulation to assess the integrated use of transketolase and omega-transaminase for the synthesis of an aminotriol. BIOCATAL BIOTRANSFOR , 24 (6) 449 - 457. 10.1080/10242420601068668.

Chen, BH; Sayar, A; Kaulmann, U; Dalby, PA; Ward, JM; Woodley, JM; (2006) 'Reaction modelling and simulation to assess the integrated use of transketolase and w-transaminase for the synthesis of an aminotriol. Biocatalysis and Biotransformations , 24 pp. 449-457.

Chen, BH; Sayar, A; Kaulmann, U; Dalby, PA; Ward, JM; Woodley, JM; (2006) Reaction modelling and simulation to assess the integrated use of transketolase and ω-transaminase for the synthesis of an aminotriol. In: (pp. pp. 449-457).

Chen, BH; Sayar, A; Micheletti, M; Woodley, JM; (2006) Transketose mediated carbon-carbon bond synthesis. Presented at: Industrial Biotransformations.

Chen, BH; Sayar, A; Woodley, JM; (2006) A hybrid approach to bioreaction kinetic parameter estimation. Presented at: 19th International Symposium on Chemical Reaction Engineering (ISCRE19).

Chhatre, S; Francis, R; O Donovan, K; Titchener-Hooker, NJ; Newcombe, AR; Keshavarz-Moore, E; (2006) A prototype decision-support computer model for evaluating the financial and technical impacts of developing and implementing changes in biopharmaceutical manufacturing processes. In: (Proceedings) Annual bioprocess UK Conference. : Edinburgh.

Chhatre, S; Francis, R; O'Donovan, K; Nigel, T-H; Newcombe, A; Keshavarz-Moore, E; (2006) A software tool for assessing the financial and technical impacts of changing industrial bio-manufacturing processes. In:

Chhatre, S; Jones, C; Francis, R; O Donovan, K; Titchener-Hooker, NJ; Newcombe, A; Keshavarz-Moore, E; (2006) Bioprocess modelling for rapid flowsheet evaluation from early stage development to post-market changes. In: (Proceedings) Technology Transfer for Biopharmaceuticals Conference. : Amsterdam, The Netherlands.

Chhatre, S; Jones, C; Francis, R; O'Donovan, K; Titchener-Hooker, N; Newcombe, A; Keshavarz-Moore, E; (2006) The integrated simulation and assessment of the impacts of process change in biotherapeutic antibody production. Biotechnol Prog , 22 (6) pp. 1612-1620. 10.1021/bp0602000.

Chhatre, SA; Francis, R; O'Donovan, K; Zhou, Y; King, J; Titchener-Hooker, N; Newcombe, AR; (2006) Global Sensitivity Analysis for the determination of parameter importance in Protein A chromatography. In: (Proceedings) European Modelling Symposium.

D

DARTNELL, LR; Ward, JM; COATES, AJ; (2006) UNSPECIFIED In: (Proceedings) Modelling the Martian radiation environment and implications for astrobiology. (pp. 2386--).

Dalby, PA; (2006) High-throughput measurement of protein stability in microtiter plates. In: (Proceedings) Inaugural Engineering Protein Therapeutics for Delivery at the Protein Engineering Summit. : Cambridge Healthtech Institute, Boston, USA.

Dalby, PA; (2006) High-throughput measurement of protein stability in microtiter plates. In: (Proceedings) ACHEMA 2006, 28th International Exhibition-Congress on Chemical Engineering, Environmental Protection and Biotechnology. : Frankfurt, Germany.

Dimitriadou, EK; Lye, GJ; Dalby, PA; (2006) Light-emitting biosensor by redesign of photoprotein aequorin. In: (Proceedings) International Congress on Biocatalysis Biocat 2006. : Hamburg, Germany.

Doig, SD; Baganz, F; Lye, GJ; (2006) High-throughput screening and process optimisation. In: Basic Biotechnology: Third Edition. (pp. 289-306).

E

Edwards-Parton, S; Bracewell, D; Thornhill, NF; Liddell, J; Titchener-Hooker, NJ; (2006) Application of partial least squares to sparse data sets for design and optimisation of chromatographic separations. In: (Proceedings) Recovery of Biological Products 12. : Phoenix, Arizona, USA.

F

Fish, S.; (2006) Enhancing the oxygen supply to whole-cell oxygenase bioconversions. Doctoral thesis, University of London. Green open access
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H

Hailes, HC; Smith, MEB; Smithies, K; Dalby, PA; Ward, JM; Woodley, JM; (2006) Chemoenzymatic synthesis of amniodiols: Engineering and directed evolution of biocatalytic pathways. In: (Proceedings) Catalysis and Biocatalysis in Green Chemistry Conference. : Cambridge.

Hailes, HC; Smith, MEB; Smithies, K; Hibbert, EG; Kaulmann, U; Senussi, TO; Costelloe, S; (2006) Ketodiol and aminodiol synthesis. In: (Proceedings) Biocatalysis Gordon Research Conference. : Smithfield, LI, USA.

Hailes, HC; Woodley, JM; (2006) Biocatalytic reaction development for synthetic chemistry. Chemistry Today , 24 pp. 3-4.

Hernandez, D; I R, S; E, A; (2006) Characterization of targeted mouse embryonic stem cells. In: Phillips, IR and Shephard, EA, (eds.) Cytochrome P450 protocols. (pp. 321-327). Humana Press: Totowa, New Jersey.

Hilker, I; Baldwin, CVF; Alphand, V; Furstoss, R; Woodley, JM; Wohlgemuth, R; (2006) On the influence of oxygen and cell concentration in an SFPR whole-cell biocatalytic Baeyer-Villiger oxidation process. Biotechnology and Bioengineering , 93 pp. 1138-1144.

Hoare, M; (2006) Use of novel ultra scale-down methods for the early design of full-scale bioprocess operations for advanced biopharmaceuticals. In: (Proceedings) CHEMA 2006 28th International Exhibition – Congress on Chemical Engineering, Environmental Protection and Biotechnology. : Frankfurt, Germany.

Hoare, M; Levy, MS; Ward J, D; P, ; (2006) Bioprocess enquiry issues to be faced for large-scale production of a DNA vaccine for a influenza pandemic. In: (Proceedings) Vaccine Technology Engineering Conferences International. : Puerto Vallerta, Mexico.

I

III, LLR; DeMello, CJ; Velayudhan, A; Teeters, M; Liu, C; (2006) BIOT 334-Comparison of cation exchange resins using a therapeutic antibody: Experimental and theoretical studies. ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY , 232

Ingram, C.U.; (2006) Biocatalytic synthesis of amino-alcohols using a de novo designed transketolase-/beta-alanine: Pyruvate transaminase pathway in Escherichia coli. Doctoral thesis, University of London. Green open access
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Islam, R; Tisi, D; Levy, MS; Lye, GJ; (2006) Novel engineering tools to aid drug discovery processes. Presented at: Protein Science Forum.

J

Jackson, NB; Liddell, JM; Lye, GJ; (2006) An automated microscale technique for the quantitative and parallel analysis of microfiltration operations. Journal of Membrane Science (276) pp. 31-34.

Joseph, JR; Sinclair, A; Titchener-Hooker, NJ; Zhou, YH; (2006) A framework for assessing the solutions in chromatographic process design and operation for large-scale manufacture. J CHEM TECHNOL BIOT , 81 (6) 1009 - 1020. 10.1002/jctb.1508.

K

Kaulmann, U; Smithies, K; Smith, MEB; Woodley, JM; Ward, JM; (2006) Towards a two-step enzymatic system for chiral aminodiol formulation. Presented at: Multistep Enzyme Catalysed Process,.

King, JMP; Titchener-Hooker, NJ; Zhou, Y; (2006) Identification of key bioprocess variables using global sensitivity analysis. In:

Kolade, OO; Bamford, VA; Anton, GA; Jones, JDG; Vera, P; Hemmings, AM; (2006) In vitro characterization of the cysteine-rich capping domains in a plant leucine rich repeat protein. BBA-PROTEINS PROTEOM , 1764 (6) pp. 1043-1053. 10.1016/j.bbapap.2006.03.014.

Kong, S; Titchener-Hooker, N; Levy, MS; (2006) Plasmid DNA processing for gene therapy and vaccination: Studies on the membrane sterilisation filtration step. Journal of Membrane Science , 280 (1-2) 824 - 831. 10.1016/j.memsci.2006.03.003.

Kong, S; Zhang, H; Hoare, M; Ward, JM; Titchener-Hooker, NJ; Levy, MS; (2006) Plasmid DNA processing for gene therapy and vaccination: studies on the membrane sterilisation filtration step, Vaccine Technology. In: (Proceedings) Engineering Conferences International. : Puerto Vallarta, Mexico.

Krin, E; Chakroun, N; Turlin, E; Givaudan, A; Gaboriau, F; Bonne, I; Rousselle, JC; (2006) Pleiotropic role of quorum-sensing autoinducer 2 in Photorhabdus luminescens. Appl Environ Microbiol , 72 (10) pp. 6439-6451. 10.1128/AEM.00398-06.

L

Lakhdar, K; Farid, SS; Savery, J; Titchener-Hooker, NJ; Papageorgiou, LG; (2006) Medium term planning of biopharmaceutical manufacture under uncertainty. In: (Proceedings) 16th European Symposium on Computer Aided Process Engineering.

Lakhdar, K; Farid, SS; Titchener-Hooker, NJ; Papageorgiou, LG; (2006) Medium term planning of biopharmaceutical manufacture with uncertain fermentation titers. Biotechnology Progress , 22 (6) pp. 1630-1636. 10.1021/bp0601950.

Law, HEM; Baldwin, CVF; Chen, BH; Woodley, JM; (2006) Process limitations in a whole-cell catalysed oxidation: Sensitivity analysis. CHEMICAL ENGINEERING SCIENCE , 61 (20) pp. 6646-6652. 10.1016/j.ces.2006.06.007.

Lien, H; Woodley, JM; (2006) A dual resin concept for overcoming substrate / product inhibition during biocatalytic processes. Presented at: CBioSep - WGDSP Meeting.

Lim, AC; Washbrook, J; Titchener-Hooker, NJ; Farid, SS; (2006) A computer-aided approach to compare the production economics of fed-batch and perfusion culture under uncertainty. BIOTECHNOL BIOENG , 93 (4) 687 - 697.

Lye, GJ; (2006) Engineering Characterisation of a mocrowell platform for the high throughput culture of suspension and adherent cell lines. Presented at: Cell Culture Engineering X.

Lye, GJ; (2006) One-pot chiral amino-alcohol biosynthesis. Industrial Bioprocessing , 28 (9) pp. 6-7.

M

Mannall, G.J.; (2006) Characterisation of the effect of process factors upon protein refolding yield. Doctoral thesis, University of London. Green open access
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Mannall, GJ; Titchener-Hooker, NJ; Chase, HA; Dalby, PA; (2006) A critical assessment of the impact of mixing on dilution refolding. Biotechnology and Bioengineering , 93 (5) pp. 955-963. 10.1002/bit.20796.

Mason, C; (2006) Other approaches to fighting cardiovascular disease: Stem cells and engineered tissue. Medical Device Technology , 17 (1) pp. 26-27.

Mason, C; (2006) A blueprint for the future. Innovation UK pp. 50-51.

Mason, C; Hoare, M; (2006) Regenerative medicine bioprocessing: The need to learn from the experience of other fields. Regenerative Medicine , 1 (5) pp. 615-623. 10.2217/17460751.2.3.227.

Mason, C; Veraitch, FS; Chu, C; Pittarello, L; Scott, R; (2006) Preliminary studies in the automation of stem cell bioprocessing. Presented at: Stem Cells Keystone Symposia.

Mason, C; Veraitch, FS; Scott, R; Lye, G; (2006) The automation of stem cell bioprocessing - prelimiary studies comparing human mesenchymal stem cell and mouse embryinic stem cell expansion. Presented at: Annual meeting of the International Society for Stem Cell Research.

Mason, CC-AWTBSI; (2006) PAS 83 - Guidance on standards, standardised methods and regulation for cell-based therapeutics, from basic research to clinical application. [Book]. Department of Trade and Industry (DTI)/British Standards Institute (BSi)

Micheletti, M; Barrett, T; Doig, SD; Baganz, F; Levy, MS; Woodley, JM; Lye, GJ; (2006) Fluid mixing in shaken bioreactors: Implications for scale-up predictions from microlite scale microbial and mammalian cel cultures. Presented at: Fluid Mixing XIII.

Micheletti, M; Barrett, T; Doig, SD; Baganz, F; Levy, MS; Woodley, JM; Lye, GJ; (2006) Fluid mixing in shaken bioreactors: Implications for scale-up predictions from microlitre-scale microbial and mammalian cell cultures. CHEMICAL ENGINEERING SCIENCE , 61 (9) 2939 - 2949. 10.1016/j.ces.2005.11.028.

Micheletti, M; Hibbert, EG; Kaulmann, U; Ingram, CU; Ward, JM; Dalby, PA; Lye, GJ; (2006) Microscale process evaluation of evolved and metabolically engineered biocatalysts. In: (Proceedings) Laboratory Automation Conference. : Philadelphia, USA.

Micheletti, M; Lye, G; (2006) Fluid mixing in bioreactors. Presented at: IChemE Fluid Mixing Processes Subject Group meeting.

Micheletti, M; Woodley, JM; (2006) Automated microscale process evaluation of recombinant biocatalyst libraries. Presented at: Laboratory Automation.

Mukhopadhyay, TK; Gorringe, A; Allison, N; Levy, MS; Lye, GJ; (2006) Rapid vaccine development using microwell based platforms. Presented at: Vaccine Technology. Engineering Conferences International.

N

Nealon, A.J.; (2006) Microwell methods for fast process development. Doctoral thesis, University of London. Green open access
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O

Oliveira, P; Batagov, A; Ward, J; Baganz, F; Krabben, P; (2006) Identification of Erythrobactin, a Hydroxamate-Type Siderophore Produced by Saccharopolyspora erythraea. Letters in Applied Microbiology , 42 pp. 375-380.

P

Pelling, AE; Veraitch, FS; Chu, C; Mason, C; Horton, MA; (2006) A dynamic oscillation in cell membrane stiffness is an early indicator of apoptosis in human cells. Presented at: International Conference on Nanoscience and Technology.

Pelling, AE; Veraitch, FS; Horton, MA; Mason, C; (2006) Atomic force microscopy and con-focal imaging of living cells and tissues. Presented at: Global Imaging Summit: Cell Therapies/Stem Cells Imaging Symposium.

Pheasey, N; Joseph, J; Love, C; Coffin, R; Hoare, M; M Ward, JM; Levy, MS; (2006) A capillary cytometer method to quantitative viable virus particles based on early detection of viral antigens and cellular events within single cells. Journal of Virological Methods , 137 (2) pp. 213-218.

Pheasey, N; Joseph, JR; Coffin, R; Hoare, M; Ward, JM; Levy, MS; (2006) Quantitation of infective viral particles by capillary cytometry. Presented at: Vaccine Technology Engineering Conferences International.

Q

Qvist, C; Baldascini, H; Bilsborough, S; Racher, A; Hoare, M; (2006) Determination of the glycosylation status of intact recombinant human antibodies using time of flight mass spectrometry. Presented at: 17th International Mass Spectometry Conference.

Qvist, C; Baldascini, H; Hutchinson, N; Bracewell, D; Smales M, H; M, ; (2006) Impact of cell bioprocessing on antibody structure and recovery. Presented at: ESACT, 16th Annual Meeting in Cell Technology.

S

Salisbury, RS; Bracewell, DG; Titchener-Hooker, NJ; (2006) A methodology for the graphical determination of operating conditions of chromatographic sequences incorporating the trade-offs between purity and yield. J CHEM TECHNOL BIOT , 81 (11) 1803 - 1813. 10.1002/jctb.1607.

Salte, H.; (2006) Rapid evaluation of options for the primary recovery of antibody fragments expressed in high cell density cultures. Doctoral thesis, University of London. Green open access
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Scott, R; Veraitch, FS; Gerontas, S; Lye, GJ; Mason, C; (2006) The effect of microwell size and inoculation density on the automated processing of stem cells. Presented at: Cell Culture Engineering X.

Scott, R; Veraitch, FS; Gerontas, S; Lye, GJ; Mason, C; (2006) The effect of microwell size and inoculation density on the automated processing of stem cells. Presented at: 1st UK Mesenchymal Stem Cell Meeting.

Shaeri, J; Wohlgemuth, R; Woodley, JM; (2006) Semi-quantititive process screening for the biocatalytic synthesis of D-xylulose 5-phosphate. Organic Process Research and Development (10) pp. 605-610.

Shorrock, V.J.; (2006) An NADH dependent reductase for isolated enzyme and whole cell catalysis. Doctoral thesis, University of London. Green open access
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Simaria, AS; Zanella de Sa, M; Vilarinho, PM; (2006) Designing flexible U-shaped assembly lines. In: Proceedings of EUROMA 2006 Conference.

Smith, MEB; Smithies, K; Hibbert, EG; Kaulmann, U; Senussi, T; Costelloe, S; Hailes, HC; (2006) Biocatalytic and organocatalytic approaches to ketodiols and aminodiols. In: (Proceedings) IUPAC International Conference of Biodiversity and Natural Products. : Kyoto, Japan.

Smithies, K; Kaulmann, U; Smith, MEB; Ward, JM; Woodley, JM; Hailes, HC; (2006) Combining organocatalysis and enzyme catalysis: Carbon-carbon bon formation followed by amination. Presented at: International symposium on Organocatalysis in Organic Synthesis.

T

Thilliaivinayagalingam, P; O'Donovan, K; Newcombe, AR; Keshavarz-Moore, E; (2006) Application of engineering principles to optimise an industrial affinity process. Presented at: Fluid Separations Subject Group, IChemE.

Tran, R; Joseph, J; Bracewell, DG; Zhou, Y; Titchener-Hooker, NJ; (2006) Mission Compressible: Generating a Framework for the Evaluation of Compressible Media on Scale Up. Presented at: Oral presentation at GE Healthcare, Uppsala, Sweden.

V

Veraitch, FS; Scott, R; Chu, C; Pittarello, L; Lye, G; Mason, C; (2006) The effect of microwell size and inoculation density on the automated processing of stem cells. Presented at: Cell Culture Engineering X.

Vilarinho, PM; Simaria, AS; (2006) ANTBAL: an ant colony optimization algorithm for balancing mixed-model assembly lines with parallel workstations. INT J PROD RES , 44 (2) 291 - 303. 10.1080/00207540500227612.

W

Wall, I; Baird, D; Price, P; Harding, KG; Kipling, D; Thomas, DW; Stephens, P; (2006) Chronic wound fibroblasts: ageing before their time? In: Wound Repair Regen. (pp. A29 - A29).

Wenger, M; DePhillips, P; Bracewell, D; (2006) Bioprocess on a Deck: A Microscale Purification for Accelerating Upstream Process Development. Presented at: ACS Fall 2006 Meeting.

Wenger, MD; DePhillips, P; Price, CE; Bracewell, DG; (2006) Bioprocess on a deck: an automated microscale chromatographic purification to rapidly evaluate saccharomyces cerevisiae fermentation performance in the optimisation of HPV virus-like particle expression. Presented at: 232nd ACS National Meeting.

Woodley, JM; (2006) (2006) Biocatalysis at the interface of engineering, molecular biology and chemistry. Presented at: Oral presentation at BERN Annual Meeting.

Woodley, JM; (2006) Choice of biocatalyst form for scaleable processes. Biochemical Society Transactions (34) pp. 301-303.

Woodley, JM; (2006) Microbial biocatalytic processes and their development. Advances in Applied Microbiology , 60 pp. 1-15.

Woodley, JM; (2006) Scale-up issues for whole-cell biocatalytic oxidation. Presented at: Greenchem symposium: Efficient biocatalytic routes for selective introduction of oxygen.

Woodley, JM; (2006) Tools for rapid biocatalytic process development. Presented at: Process R and D summit.

Z

Zhou, Y; Kim, H; (2006) A new algorithm for bioprocess feasibility index under uncertainty. In:

This list was generated on Sun Sep 25 06:01:07 2016 BST.