Tisdall, M.M.;
Smith, M.;
(2006)
Cerebral microdialysis: research technique or clinical tool.
British Journal of Anaesthesia
, 97
(1)
pp. 18-25.
10.1093/bja/ael109.
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Abstract
Cerebral microdialysis is a well-established laboratory tool that is increasingly used as a bedside monitor to provide on-line analysis of brain tissue biochemistry during neuro-intensive care. This review describes the principles of cerebral microdialysis and the rationale for its use in the clinical setting, including discussion of the most commonly used microdialysis biomarkers of acute brain injury. Potential clinical applications are reviewed and future research applications identified. Microdialysis has the potential to become an established part of mainstream multimodality monitoring during the management of acute brain injury but at present should be considered a research tool for use in specialist centres.
| Type: | Article |
|---|---|
| Title: | Cerebral microdialysis: research technique or clinical tool |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1093/bja/ael109 |
| Publisher version: | http://dx.doi.org/10.1093/bja/ael109 |
| Language: | English |
| Keywords: | Brain – injury, Monitoring - intensive care, Metabolism – metabolites, Monitoring - microdialysis |
| UCL classification: | UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation |
| URI: | https://discovery.ucl.ac.uk/id/eprint/2477 |
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