UCL Discovery
UCL home » Library Services » Electronic resources » UCL Discovery

Spine Oncology—Metastatic Spine Tumors

Choi, D; Bilsky, M; Fehlings, M; Fisher, C; Gokaslan, Z; (2017) Spine Oncology—Metastatic Spine Tumors. Neurosurgery , 80 (3) S131-S137. 10.1093/neuros/nyw084. Green open access

[thumbnail of Choi_metastatic_spine_tumors.pdf]
Preview
Text
Choi_metastatic_spine_tumors.pdf - Accepted Version

Download (876kB) | Preview

Abstract

Surgery for spinal metastases remains the mainstay treatment for pain, instability, and neurological deterioration due to tumor infiltration of the spine. However, several new therapies are emerging which may improve outcomes further, and in some cases even replace the need for surgery. We now have a better understanding of which factors influence survival and quality of life after surgery, and this underpins the development and application of new treatments, and assessment of outcome. Depending on genetic subtyping of tumors, novel immunotherapies and chemotherapies may be very effective in prolonging quality of life. New surgical techniques allow smaller, quicker, and safer operations with less blood loss, pain, and quicker recovery after surgery. Radiation treatments have also leapt forward with the greater accuracy and higher doses possible from intensity-modulated photon radiation, stereotactic body radiation treatment, proton beam therapy, or carbon ion treatment. Combined with more advanced materials for vertebral body stabilization, computer navigation systems, and robotics, more can be done at earlier or later stages of the spinal disease than was previously possible, resulting in more options and improved outcomes for patients.

Type: Article
Title: Spine Oncology—Metastatic Spine Tumors
Open access status: An open access version is available from UCL Discovery
DOI: 10.1093/neuros/nyw084
Publisher version: https://doi.org/10.1093/neuros/nyw084
Language: English
Additional information: This version is the author accepted manuscript. For information on re-use, please refer to the publisher’s terms and conditions.
Keywords: Spine, Tumor, Metastasis, Surgery
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Brain Sciences > UCL Queen Square Institute of Neurology > Brain Repair and Rehabilitation
URI: https://discovery.ucl.ac.uk/id/eprint/1565085
Downloads since deposit
197Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item