Tedesco, FS;
Moyle, LA;
Perdiguero, E;
(2017)
Muscle Interstitial Cells: A Brief Field Guide to Non-satellite Cell Populations in Skeletal Muscle.
In: Perdiguero, E and Cornelison, DDW, (eds.)
Muscle Stem Cells: Methods and Protocols (Part III).
(pp. 129-147).
Springer New York: New York, USA.
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Abstract
Skeletal muscle regeneration is mainly enabled by a population of adult stem cells known as satellite cells. Satellite cells have been shown to be indispensable for adult skeletal muscle repair and regeneration. In the last two decades, other stem/progenitor cell populations resident in the skeletal muscle interstitium have been identified as "collaborators" of satellite cells during regeneration. They also appear to have a key role in replacing skeletal muscle with adipose, fibrous, or bone tissue in pathological conditions. Here, we review the role and known functions of these different interstitial skeletal muscle cell types and discuss their role in skeletal muscle tissue homeostasis, regeneration, and disease, including their therapeutic potential for cell transplantation protocols.
| Type: | Book chapter |
|---|---|
| Title: | Muscle Interstitial Cells: A Brief Field Guide to Non-satellite Cell Populations in Skeletal Muscle |
| Location: | United States |
| ISBN-13: | 9781493967698 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-1-4939-6771-1_7 |
| Publisher version: | http://dx.doi.org/10.1007/978-1-4939-6771-1_7 |
| Language: | English |
| Additional information: | Copyright © 2017 Springer Science+Business Media LLC. The final publication is available at Springer via http://dx.doi.org/10.1007/978-1-4939-6771-1_7. |
| Keywords: | Fibro-adipogenic progenitors, Interstitial cells, Mesenchymal progenitors, Mesoangioblasts, Muscle regeneration, Pericytes, Pw1, Skeletal muscle, Stem cells |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Cell and Developmental Biology |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1544387 |
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