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Myocardial tissue characterization: histological and pathophysiological correlation

Treibel, TA; White, SK; Moon, JC; (2014) Myocardial tissue characterization: histological and pathophysiological correlation. Curr Cardiovasc Imaging Rep , 7 (3) , Article 9254. 10.1007/s12410-013-9254-9. Green open access

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Abstract

Cardiovascular magnetic resonance imaging (CMR) has become the gold standard not only for cardiac volume and function quantification, but for a key unique strength: non-invasive myocardial tissue characterization. Several different techniques, separately or in combination, can detect and quantify early and established myocardial pathological processes permitting better diagnosis, prognostication and tracking of therapy. The authors will focus on the histological and pathophysiological evidence of these imaging parameters in the characterization of edema, infarction, scar and fibrosis. In addition to laying out the strengths and weaknesses of each modality, the reader will be introduced to rapid developments in T1 and T2 mapping as well as the use of contrast-derived extracellular volume for quantification of diffuse fibrosis.

Type: Article
Title: Myocardial tissue characterization: histological and pathophysiological correlation
Open access status: An open access version is available from UCL Discovery
DOI: 10.1007/s12410-013-9254-9
Publisher version: http://dx.doi.org/10.1007/s12410-013-9254-9
Additional information: © Springer Science+Business Media New York 2014. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: Edema, LGE, Late enhancement, Myocardial fibrosis, T1, T2
UCL classification: UCL
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science
URI: https://discovery.ucl.ac.uk/id/eprint/1420744
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