GUNNING, J;
CUTBUSH, S;
KURODA, R;
NEIDLE, S;
(1984)
MOLECULAR-MODELLING AND BIOPHYSICAL STUDIES ON MODIFIED AND UNMODIFIED OLIGONUCLEOTIDES.
ACTA CRYSTALLOGRAPHICA SECTION A
, 40
(Supple)
C46 - C46.
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Abstract
Computer graphics modelling and energy calculations have been carried out on a series of modified and unmodified oligonucleotides to investigate the effects of base deletion, base substitution and base methylation, particularly 06-methylguanine and 5-methylcytosine, as well as the substitution of bases by analogues.
| Type: | Article |
|---|---|
| Title: | MOLECULAR-MODELLING AND BIOPHYSICAL STUDIES ON MODIFIED AND UNMODIFIED OLIGONUCLEOTIDES |
| Open access status: | An open access version is available from UCL Discovery |
| Publisher version: | http://scripts.iucr.org/cgi-bin/paper?a48842 |
| Language: | English |
| Additional information: | Copyright © International Union of Crystallography |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > UCL School of Pharmacy |
| URI: | https://discovery.ucl.ac.uk/id/eprint/1367912 |
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