Chiesa, STC;
Rapala, A;
Charakida, M;
Wade, K;
Timpson, N;
Deanfield, J;
(2018)
The ‘ALSPAC in London’ dataset: adiposity, cardiometabolic risk profiles, and the emerging arterial phenotype in young adulthood [version 1; referees: awaiting peer review].
Wellcome Open Research
, 3
(162)
10.12688/wellcomeopenres.14942.1.
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Abstract
Rising rates of adiposity in the young pose one of the greatest threats to future population burden of cardiovascular disease. Understanding the contribution of genetic and early-life influences to adiposity profiles in young adulthood – when the first signs of subclinical cardiovascular disease commonly appear – are vital if effective lifetime prevention strategies are to be developed. This data note documents the extensive range of genotypic and phenotypic data available from a London-based sub-study of the long-running Avon Longitudinal Study of Parents and Children (ALSPAC)—the ‘ALSPAC in London’ Study—in which extensive adipose and cardiovascular phenotyping was carried out in participants recruited based on a genetic predisposition to obesity.
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