Keddie, S;
Jaunmuktane, Z;
Brandner, S;
Shah, S;
Maddison, P;
Rees, JH;
Hanna, MG;
... Carr, AS; + view all
(2018)
A diagnostic conundrum.
Practical Neurology
, 18
(2)
pp. 137-142.
10.1136/practneurol-2017-001801.
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Abstract
A 26-year-old man was referred with facial weakness, dysarthria, dysphagia, ophthalmoparesis and severely weak and wasted legs. His symptoms had begun when aged 20 with electric shock pains and paraesthesia in both feet progressing over 6 months to the lower calves. He then developed buttock numbness and occasional faecal incontinence. By age 22, he had diffuse lower limb weakness and wasting, with difficulty standing from a seated position and frequent tripping. He became wheelchair-dependent within 3 years.
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