Martin, CA;
Nunn, L;
Lambiase, PD;
(2017)
Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation.
Indian Pacing and Electrophysiology Journal
, 17
(4)
pp. 113-115.
10.1016/j.ipej.2017.05.006.
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Abstract
A young man suffered cardiac arrests with polymorphic ventricular tachycardia (PVT) and ventricular fibrillation (VF) triggered by ventricular premature contractions (PVCs). The arrhythmia was resistant to anti-arrhythmics, so after ICD implantation he underwent successful ablation of the triggering VE beat, which was pace-mapped to the left posterior hemi-fascicle. We review the evidence for the role of the Purkinje network in the initiation and maintenance of PVT and VF, postulating a channelopathy as a possible underlying cause, and provide recommendations for PVC ablation.
| Type: | Article |
|---|---|
| Title: | Syncope in a young man: Role of Purkinje fibres in idiopathic ventricular fibrillation |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1016/j.ipej.2017.05.006 |
| Publisher version: | http://doi.org/10.1016/j.ipej.2017.05.006 |
| Language: | English |
| Additional information: | Copyright © 2017, Indian Heart Rhythm Society. Production and hosting by Elsevier B.V. This is an open access article under the CC BY-NC-ND license (http:// creativecommons.org/licenses/by-nc-nd/4.0/). |
| Keywords: | Ventricular fibrillation; Sudden cardiac death; Purkinje fibres; Channelopathy |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science > Clinical Science |
| URI: | https://discovery.ucl.ac.uk/id/eprint/10027962 |
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