Cohen-Gonsaud, M and Keep, NH and Davies, AP and Ward, J and Henderson, B and Labesse, G (2004) Resuscitation-promoting factors possess a lysozyme-like domain. TRENDS BIOCHEM SCI , 29 (1) 7 - 10. 10.1016/j.tibs.2003.10.009.
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Abstract
The novel bacterial cytokine family - resuscitation-promoting factors (Rpfs) - share a conserved domain of uncharacterized function. Predicting the structure of this domain suggests that Rpfs possess a lysozyme-like domain. The model highlights the good conservation of residues involved in catalysis and substrate binding. A lysozyme-like function makes sense for this domain in the light of experimental characterization of the biological function of Rpfs.
| Type: | Article |
|---|---|
| Title: | Resuscitation-promoting factors possess a lysozyme-like domain |
| DOI: | 10.1016/j.tibs.2003.10.009 |
| Keywords: | AUTOCRINE GROWTH-FACTORS, EGG-WHITE LYSOZYME, MYCOBACTERIUM-TUBERCULOSIS, RECOGNITION, PREDICTION, PROFILES, PROTEINS, DATABASE, MODELS |
| UCL classification: | UCL > School of Life and Medical Sciences > Faculty of Life Sciences > Biosciences (Division of) UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Eastman Dental Institute > Microbial Diseases UCL > School of BEAMS > Faculty of Engineering Science > Biochemical Engineering |
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