UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Apolipoprotein C-III gene variation and dyslipidaemia

Talmud, PJ; Humphries, SE; (1997) Apolipoprotein C-III gene variation and dyslipidaemia. CURR OPIN LIPIDOL , 8 (3) 154 - 158.

Full text not available from this repository.

Abstract

Within the apolipoprotein A-I-C-III-A-IV gene cluster, the Sstl polymorphism in the 3' untranslated region of the apolipoprotein C-III gene is the variant site most consistently and strongly associated with raised plasma triglyceride levels and coronary artery disease, To date the molecular mechanisms that underlie this effect have not been fully identified and variation within the insulin-responsive element of the apolipoprotein C-III proximal promoter cannot entirely explain the Sstl effect.

Type:Article
Title:Apolipoprotein C-III gene variation and dyslipidaemia
Keywords:DENSITY-LIPOPROTEIN CHOLESTEROL, JAPANESE POPULATION, TRANSGENIC MICE, HEART-DISEASE, APO-CIII, I GENE, HYPERTRIGLYCERIDEMIA, CLUSTER, REGION, POLYMORPHISMS
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

Archive Staff Only: edit this record