UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

An enantioselective synthesis of the bicyclic core of the marine natural product awajanomycin

Pritchard, DR; Wilden, JD; (2010) An enantioselective synthesis of the bicyclic core of the marine natural product awajanomycin. TETRAHEDRON LETT , 51 (14) 1819 - 1821. 10.1016/j.tetlet.2010.01.123.

Full text not available from this repository.

Abstract

A concise stereoselective synthesis of the N-benzylated bicyclic core of the marine natural product awajanomycin is described starting with naturally Occurring L-alanine. Key steps in the synthesis include a ring-closing metathesis to establish a delta-lactam ring followed by a stereoselective hydroxylation to instal the quaternary centre. (C) 2010 Elsevier Ltd. All rights reserved.

Type:Article
Title:An enantioselective synthesis of the bicyclic core of the marine natural product awajanomycin
DOI:10.1016/j.tetlet.2010.01.123
Keywords:Ring-closing metathesis, delta-Lactam, Acremonium sp., Diastereoselective hydroxylation, VINYL HALIDES, LACTONES, CARBONYLATION, DERIVATIVES, METATHESIS, ALCOHOLS, ROUTE
UCL classification:UCL > School of BEAMS > Faculty of Maths and Physical Sciences > Chemistry

Archive Staff Only: edit this record