UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Optical tomography of a realistic neonatal head phantom

Gibson, A; Yusof, RM; Dehghani, H; Riley, J; Everdell, N; Richards, R; ... Delpy, DT; + view all (2003) Optical tomography of a realistic neonatal head phantom. In: APPLIED OPTICS. (pp. 3109 - 3116). OPTICAL SOC AMER

Full text not available from this repository.

Abstract

We have begun clinical trials of optical tomography of the neonatal brain. To validate this research, we have built and imaged an anatomically realistic, tissue-equivalent neonatal head phantom that is hollow, allowing contrasting objects to be placed inside it. Images were reconstructed by use of two finite-element meshes, one generated from a computed tomography image of the phantom and the other spherical. The phantom was filled with a liquid of the same optical properties as the outer region, and two perturbations were placed inside. These were successfully imaged with good separation between the absorption and scatter coefficients. The phantom was then refilled with a liquid of increased absorption compared with the background to simulate the brain, and the absolute properties of the two regions were found. These were used as a priori information for the complete reconstruction. Both perturbations were visible, superimposed on the increased absorption of the central region. The head-shaped mesh performed slightly better than the spherical mesh, particularly when the absorption of the central region of the phantom was increased. (C) 2003 Optical Society of America.

Type:Proceedings paper
Title:Optical tomography of a realistic neonatal head phantom
Event:Biomedical Topical Meeting of the Optical-Society-of-America
Location:MIAMI BEACH, FL
Dates:2002
Keywords:NEAR-INFRARED SPECTROSCOPY, IMAGE-RECONSTRUCTION, SCATTERING MEDIA, BRAIN, LIGHT, HEMODYNAMICS, BOUNDARY, REGIONS, TISSUE
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

Archive Staff Only: edit this record