Schirmer, JM; Fass, DN; Byrne, GW; Tazelaar, HD; Logan, JS; McGregor, CG; (2004) Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival. Xenotransplantation , 11 (5) 436 - 443. 10.1111/j.1399-3089.2004.00159.x.
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Microvascular thrombosis is a prominent characteristic of delayed xenograft rejection, therefore the effects of antiplatelet therapy with aspirin and clopidogrel on long-term cardiac xenograft function was investigated in a heterotopic pig-to-baboon cardiac transplant model.
|Title:||Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival.|
|Keywords:||Animals, Animals, Genetically Modified, Antigens, CD, Antigens, CD46, Aspirin, Graft Rejection, Graft Survival, Heart Transplantation, Humans, Membrane Glycoproteins, Papio anubis, Platelet Aggregation, Platelet Aggregation Inhibitors, Swine, Ticlopidine, Time Factors, Transplantation, Heterologous|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science|
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