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Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival.

Schirmer, JM; Fass, DN; Byrne, GW; Tazelaar, HD; Logan, JS; McGregor, CG; (2004) Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival. Xenotransplantation , 11 (5) 436 - 443. 10.1111/j.1399-3089.2004.00159.x.

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Abstract

Microvascular thrombosis is a prominent characteristic of delayed xenograft rejection, therefore the effects of antiplatelet therapy with aspirin and clopidogrel on long-term cardiac xenograft function was investigated in a heterotopic pig-to-baboon cardiac transplant model.

Type:Article
Title:Effective antiplatelet therapy does not prolong transgenic pig to baboon cardiac xenograft survival.
Location:Denmark
DOI:10.1111/j.1399-3089.2004.00159.x
Language:English
Keywords:Animals, Animals, Genetically Modified, Antigens, CD, Antigens, CD46, Aspirin, Graft Rejection, Graft Survival, Heart Transplantation, Humans, Membrane Glycoproteins, Papio anubis, Platelet Aggregation, Platelet Aggregation Inhibitors, Swine, Ticlopidine, Time Factors, Transplantation, Heterologous
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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