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Efficient and durable gene transfer to transplanted heart using adeno-associated virus 9 vector.

Miyagi, N and Rao, VP and Ricci, D and Du, Z and Byrne, GW and Bailey, KR and Nakai, H and Russell, SJ and McGregor, CG (2008) Efficient and durable gene transfer to transplanted heart using adeno-associated virus 9 vector. J Heart Lung Transplant , 27 (5) 554 - 560. 10.1016/j.healun.2008.01.025.

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Abstract

In this investigation we studied the efficacy and durability of recombinant adeno-associated virus serotype 9 (rAAV9) vector-mediated gene transfer to the transplanted rat heart.

Type:Article
Title:Efficient and durable gene transfer to transplanted heart using adeno-associated virus 9 vector.
Location:United States
DOI:10.1016/j.healun.2008.01.025
Language:English
Additional information:PMCID: PMC2426957
Keywords:Adenoviridae, Animals, Enzyme-Linked Immunosorbent Assay, Gene Expression, Genetic Therapy, Genetic Vectors, Heart Transplantation, Male, Models, Animal, Rats, Rats, Inbred Lew, Recombination, Genetic, Reverse Transcriptase Polymerase Chain Reaction, Transduction, Genetic
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science

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