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IODIZED OIL IN THE TREATMENT OF HEPATOCELLULAR-CARCINOMA

BHATTACHARYA, S; NOVELL, JR; WINSLET, MC; HOBBS, KEF; (1994) IODIZED OIL IN THE TREATMENT OF HEPATOCELLULAR-CARCINOMA. BRIT J SURG , 81 (11) 1563 - 1571.

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Abstract

When injected into the hepatic artery the contrast agent Lipiodol (iodized poppy seed oil) is selectively retained by hepatocellular carcinoma (HCC) for a prolonged period of time. Liver computed tomography (CT) performed after Lipiodol angiography is more sensitive than ordinary CT at imaging HCC. Arterial administration of cytotoxic drugs and radioisotopes conjugated to Lipiodol has been shown to be reasonably safe inpatients with irresectable HCC. These therapies, often combined with embolization, provide effective palliation, better tumour response and improved time. Liver computed tomography (CT) performed after survival compared with other available treatments. Their use as a preoperative adjunct to surgical resection of HCC is controversial.

Type:Article
Title:IODIZED OIL IN THE TREATMENT OF HEPATOCELLULAR-CARCINOMA
Keywords:TRANSCATHETER ARTERIAL EMBOLIZATION, LIPID CONTRAST-MEDIUM, PERCUTANEOUS ETHANOL INJECTION, INTERNAL RADIATION-THERAPY, HEPATIC-ARTERY, LIVER METASTASES, COMPUTED-TOMOGRAPHY, Y-90 MICROSPHERES, TRANSARTERIAL INJECTION, I-131-LABELED LIPIODOL
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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