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TUMOR VASCULATURE - A POTENTIAL THERAPEUTIC TARGET

BAILLIE, CT; WINSLET, MC; BRADLEY, NJ; (1995) TUMOR VASCULATURE - A POTENTIAL THERAPEUTIC TARGET. BRIT J CANCER , 72 (2) 257 - 267.

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Abstract

The tumour vasculature is vital for the establishment, growth and metastasis of solid tumours. Its physiological properties limit the effectiveness of conventional anti-cancer strategies. Therapeutic approaches directed at the tumour vasculature are reviewed, suggesting the potential of anti-angiogenesis and the targeting of vascular proliferation antigens as cancer treatments.

Type:Article
Title:TUMOR VASCULATURE - A POTENTIAL THERAPEUTIC TARGET
Keywords:ANGIOGENESIS, ENDOTHELIUM, FIBROBLAST GROWTH-FACTOR, ENDOTHELIAL-CELL-PROLIFERATION, THYMIDINE PHOSPHORYLASE-ACTIVITY, FLAVONE ACETIC-ACID, NECROSIS FACTOR-ALPHA, SOLID TUMORS, MONOCLONAL-ANTIBODIES, ANGIOGENIC FACTOR, PERMEABILITY FACTOR, CARCINOMA-CELLS
UCL classification:UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of)

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