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Evidence-based treatment and quality of life in heart failure

Dobre, D; van Jaarsveld, CHM; Ranchor, AV; Arnold, R; de Jongste, MJL; Haaijer-Ruskamp, FM; (2006) Evidence-based treatment and quality of life in heart failure. J EVAL CLIN PRACT , 12 (3) 334 - 340.

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Abstract

To explore whether prescription of evidence-based drug therapy is associated with better quality of life (QoL) in patients with heart failure (HF). Patients (n = 62) were recruited in the outpatient clinic of Groningen University Hospital. Inclusion criteria were previous diagnosis of HF, age 40-80 years; ejection fraction of less than 45%, free from other serious disease (such as cancer) and psychiatric problems in the last year. QoL was assessed with the RAND 36-item health survey questionnaire, on five scales: physical functioning, mental health, social functioning, vitality and general health perception. Medication prescribed for 1 to 6 months before the QoL assessment was classified as either evidence-based treatment or under-treatment, according to the 2001 European guidelines on optimal HF treatment. The study had a cross-sectional design. QoL did not differ significantly between evidence-based and under-treated patients, unadjusted or after adjustment for significant patient imbalances. Conventional step-up medication approach in HF may have a positive impact on survival or morbidity, but it seems not beneficial in relation to QoL. Other interventions should be designed to improve QoL of patients with HF.

Type: Article
Title: Evidence-based treatment and quality of life in heart failure
Keywords: chronic heart failure, clinical practice guidelines, quality of care, quality of life, LEFT-VENTRICULAR DYSFUNCTION, BETA-BLOCKERS, PRIMARY-CARE, MANAGEMENT, POPULATION, MORTALITY, OUTCOMES
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: http://discovery.ucl.ac.uk/id/eprint/88601
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