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Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22.

Fox, MF; Lahbib, F; Pratt, W; Attwood, J; Gum, J; Kim, Y; Swallow, DM; (1992) Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22. Ann Hum Genet , 56 (4) pp. 281-287.

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Abstract

The gene MUC3 which codes for a mucin expressed in intestine (Gum et al. 1990) has previously been mapped, using somatic cell hybrids, to chromosome 7. We describe here the regional localization of MUC3 to chromosome 7q22 by in situ hybridization. Preliminary linkage analysis using CEPH (Centre d'Etude du Polymorphisme Humain) families supports this assignment and places MUC3 in the same linkage group as COL1A2 and CFTR.

Type: Article
Title: Regional localization of the intestinal mucin gene MUC3 to chromosome 7q22.
Location: England
Keywords: Amino Acid Sequence, Cells, Cultured, Chromosome Mapping, Chromosomes, Human, Pair 7, Genetic Linkage, Genetic Markers, Humans, In Situ Hybridization, Fluorescence, Lymphocytes, Molecular Sequence Data, Mucins, Polymorphism, Restriction Fragment Length
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Life Sciences > Div of Biosciences > Genetics, Evolution and Environment
URI: http://discovery.ucl.ac.uk/id/eprint/87096
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