Ramon, D; Scott, I; Cox, ST; Pesoa, S; Vullo, C; Little, AM; Madrigal, JA; (2000) HLA-A*6817, identified in the Kolla Amerindians of North-West Argentina possesses a novel nucleotide substitution. Tissue Antigens , 55 (5) 453 - 454.
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Analysis of HLA polymorphism of the indigenous populations of Central and South America has identified many alleles not seen previously in other populations. We have described a novel allele, B*5113, previously in a Kolla Amerindian individual from North-West Argentina. Here we present a second novel allele from this population: A*6817, which differs from its closest neighbour A*68012 by a single substitution at nucleotide 419. This substitution of adenosine 419 A*68012 for thymidine in A*6817 results in a novel amino acid change (aspartate to valine) at residue 116
|Title:||HLA-A*6817, identified in the Kolla Amerindians of North-West Argentina possesses a novel nucleotide substitution|
|Additional information:||LA - Eng CY - DENMARK - Article|
|Keywords:||ACID, Adenosine, allele, ALLELES, amino acid, analysis, article, BONE, Bone Marrow, BONE-MARROW, Denmark, ENGLAND, HLA, Kolla Amerindians, LA, LONDON, MARROW, MED, NORTH-WEST ARGENTINA, novel, Nucleotide, Other, polymorphism, population, POPULATIONS, Result, SINGLE, SOUTH, ST, SUBSTITUTION, Thymidine, Trust, Valine|
|UCL classification:||UCL > Pro-Provosts|
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