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The effects of exercise on haemodynamic function in relation to the familial hypertension risk model

Hamer, M; (2006) The effects of exercise on haemodynamic function in relation to the familial hypertension risk model. J HUM HYPERTENS , 20 (5) 313 - 319. 10.1038/sj.jhh.1001999.

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Abstract

Offspring hypertensives are characterized by a hyperactive sympathetic nervous system and other early cardiovascular abnormalities that increase the risk of developing hypertension. A physically active lifestyle is associated with a lower risk of hypertension, although the mechanisms are incompletely understood and likely to be multifactorial. One aspect that has received little attention is the interaction of exercise with familial hypertension risk. The present review examines the effects of exercise on haemodynamic function in relation to the familial hypertension risk model. Paradoxically, exercise may be viewed as potent stressor to the cardiovascular system, although recent studies are beginning to show that cardiovascular adaptations, primarily mediated by changes in sympatho-vagal balance, following both acute and chronic exercise may be particularly important for individuals with familial risk of hypertension. Future studies that focus on inflammatory, metabolic, and genetic pathways may uncover further beneficial effects of exercise in relation to familial risk.

Type: Article
Title: The effects of exercise on haemodynamic function in relation to the familial hypertension risk model
DOI: 10.1038/sj.jhh.1001999
Keywords: cardiovascular function, sympathetic nervous system, exercise, familial hypertension risk, BLOOD-PRESSURE RESPONSES, C-REACTIVE PROTEIN, HERITAGE FAMILY, PARENTAL HYPERTENSION, PHYSICAL-ACTIVITY, NORMOTENSIVE INDIVIDUALS, MENTAL CHALLENGE, AEROBIC FITNESS, HEART-RATE, HISTORY
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: http://discovery.ucl.ac.uk/id/eprint/85310
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