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FACTOR-V LEIDEN MUTATION, VENOUS THROMBOEMBOLISM AND COMBINED ORAL-CONTRACEPTIVE USAGE

MACHIN, SJ; MACKIE, IJ; GUILLEBAUD, J; (1995) FACTOR-V LEIDEN MUTATION, VENOUS THROMBOEMBOLISM AND COMBINED ORAL-CONTRACEPTIVE USAGE. BRIT J FAM PLAN , 21 (1) 13 - 14.

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Abstract

The abnormality known as the Leiden mutation of coagulation factor V is described. The incidence of this defect may range from 20 to 40 per cent in patients with recurrent venous thrombosis. A recent study appears to show a joint risk which is more than additive in young women who have factor V Leiden mutation and use COCs. In view of this, a screening and advice strategy is suggested.

Type: Article
Title: FACTOR-V LEIDEN MUTATION, VENOUS THROMBOEMBOLISM AND COMBINED ORAL-CONTRACEPTIVE USAGE
Keywords: POOR ANTICOAGULANT RESPONSE, ACTIVATED PROTEIN-C, THROMBOPHILIA, DEFICIENCY, PATHWAY
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Haematology
URI: http://discovery.ucl.ac.uk/id/eprint/85217
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