Waugh, MG; Hsuan, JJ; (2001) EGF receptors as transcription factors: ridiculous or sublime? NAT CELL BIOL , 3 (9) E209 - E211.
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The notion that a transmembrane receptor at the cell surface can somehow reappear as a transcription factor in the nucleus is bound to be controversial. However, there are two reported examples of this. If this hypothesis can withstand the inevitable and necessary battery of additional empirical tests, then our understanding of signal transduction needs to move in a new direction.
|Title:||EGF receptors as transcription factors: ridiculous or sublime?|
|Keywords:||GROWTH-FACTOR RECEPTOR, NUCLEAR-LOCALIZATION, IMPORT, CELLS|
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