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A new artificial urinary sphincter with conditional occlusion for stress urinary incontinence: Preliminary clinical results

Knight, SL; Susser, J; Greenwell, T; Mundy, AR; Craggs, MD; (2006) A new artificial urinary sphincter with conditional occlusion for stress urinary incontinence: Preliminary clinical results. EUR UROL , 50 (3) 574 - 580. 10.1016/j.eururo.2006.03.065.

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Abstract

Objectives: To perform a preliminary clinical investigation to determine the safety and efficacy of a novel artificial urinary sphincter (AUS) with conditional occlusion for the treatment of stress urinary incontinence.Methods: Male patients with urodynamically proven stress urinary incontinence after a prostatectomy were implanted with the novel AUS. They were followed up over a period of 12 months and the device tested for efficacy by using objective measurements of urinary leakage and continence. We derived a new measure for continence called the Continence Index.Results: We have demonstrated that the patients receiving the new AUS showed a reduction of greater than 10-fold in mean daily leakage volume from 770.6 ml to 55.1 ml. There was an overall improvement in the Continence Index from 54% to 97%.Conclusions: The new AUS with conditional occlusion provides good continence rates and enables adjustment of regulating pressure in situ. (c) 2006 European Association of Urology. Published by Elsevier B.V. All rights reserved.

Type: Article
Title: A new artificial urinary sphincter with conditional occlusion for stress urinary incontinence: Preliminary clinical results
DOI: 10.1016/j.eururo.2006.03.065
Keywords: artificial urinary sphincter, stress incontinence, post-prostatectomy
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Surgical Biotechnology
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Surgery and Interventional Sci > Department of Targeted Intervention
URI: http://discovery.ucl.ac.uk/id/eprint/8426
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