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Raynaud's phenomenon after radical radiotherapy for tumours of the head and neck

Westbury, CB; Harrington, KJ; Rhys-Evans, P; Archer, DJ; Searle, AE; Henk, JM; Black, CM; (2003) Raynaud's phenomenon after radical radiotherapy for tumours of the head and neck. POSTGRAD MED J , 79 (929) 176 - 177.

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Abstract

Endothelial cell injury is implicated in the development of radiation induced tissue damage and may also be involved in the pathophysiology of secondary Raynaud's phenomenon. Two patients are presented in whom the typical symptoms and signs of Raynaud's phenomenon developed as a late complication of radical radiotherapy. One had Raynaud's of the tongue and one of the lip. Both patients had a prior history of primary Raynaud's phenomenon and in each case the symptoms were repeatedly precipitated by sudden cold exposure. The possible pathogenesis of radiation induced Raynaud's phenomenon in the head and neck region is discussed.

Type: Article
Title: Raynaud's phenomenon after radical radiotherapy for tumours of the head and neck
Keywords: RADIATION-THERAPY, ENDOTHELIUM, CANCER
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Cancer Institute > Research Department of Oncology
URI: http://discovery.ucl.ac.uk/id/eprint/81649
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