Adenosine infusion during early reperfusion failed to limit myocardial infarct size in a collateral deficient species.
Intracoronary or intravenous adenosine during reperfusion in combination with lignocaine may attenuate "reperfusion injury" and limit myocardial infarct size in the canine heart. The aim of this study was to test whether intravenous adenosine also protects myocardium in the rabbit heart, which lacks xanthine oxidase and significant coronary collaterals in contrast to the canine heart.
|Title:||Adenosine infusion during early reperfusion failed to limit myocardial infarct size in a collateral deficient species.|
|Keywords:||Adenosine, Animals, Blood Pressure, Collateral Circulation, Male, Myocardial Infarction, Myocardial Reperfusion Injury, Myocardium, Rabbits|
|UCL classification:||UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Cardiovascular Science
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