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Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography

Becker, W; Bergmann, A; Gibson, A; Everdell, N; Jennions, D; Schweige, M; ... Hebden, JC; + view all (2005) Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography. Optical Tomography and Spectroscopy of Tissue VI , 5693 34 - 42. 10.1117/12.589004.

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Abstract

We present a multi-dimensional TCSPC technique that combines multi-detector and multiplexing capability, and records fast and virtually unlimited sequences of time-of-flight distributions. The system consists of four fully parallel TCSPC channels. Each channel records simultaneously in up to eight detection channels. Up to four lasers and 32 source positions can be multiplexed. The total count rate is up to 4 x 10(7) photons per second. Time-of-flight sequences can be recorded with a resolution of 50 to 100 ms per curve. The system is operated within a single personal computer.

Type:Article
Title:Multi-dimensional time-correlated single photon counting applied to diffuse optical tomography
Location:San Diego, CA
DOI:10.1117/12.589004
Keywords:TCSPC, diffuse optical tomography, brain imaging, NEAR-INFRARED SPECTROSCOPY, HIGHLY SCATTERING MEDIA, IN-VIVO, OXYGEN-SATURATION, BREAST-TUMORS, TURBID MEDIA, ABSORPTION, FLUORESCENCE, MAMMOGRAPHY, HEMOGLOBIN
UCL classification:UCL > School of BEAMS > Faculty of Engineering Science > Computer Science
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering

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