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Seroepidemiology and risk factors for sporadic norovirus/Mexico strain

Peasey, AE; Ruiz-Palacios, GM; Quigley, M; Newsholme, W; Martinez, J; Rosales, G; Jiang, X; (2004) Seroepidemiology and risk factors for sporadic norovirus/Mexico strain. J INFECT DIS , 189 (11) 2027 - 2036.

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Abstract

Risk factors associated with transmission of sporadic norovirus (NV; formerly Norwalk-like virus)/Mexico strain were identified in a seroepidemiological study conducted in rural Mexico. Acquisition of Mexico strain IgA antibodies was age-related; 34% of 1-4-year-olds were seropositive, compared with 81% of adults (P < .001). After 12 months, 42% of 1-4-year-olds showed a seroresponse to Mexico strain, compared with 27% of adults (P < .01). Personal and domestic hygiene measures, such as hand washing, general cleanliness of the mother's clothing, and the type of room assigned for cooking were significantly associated with odds of a seroresponse. For infants, having a dog in or near the home was a risk factor for seroresponse (P < .01), whereas, for older children, the mother's involvement in agricultural activities was a risk factor (P < .001). This study provides initial evidence of risk factors associated with sporadic NV infection. Data indicate some similarities to risk factors associated with outbreaks of NV infection.

Type: Article
Title: Seroepidemiology and risk factors for sporadic norovirus/Mexico strain
Keywords: NORWALK-LIKE VIRUSES, ROUND-STRUCTURED VIRUS, HUMAN CALICIVIRUSES, ENVIRONMENTAL CONTAMINATION, MOLECULAR EPIDEMIOLOGY, VIRAL GASTROENTERITIS, ENZYME IMMUNOASSAYS, HOSPITAL OUTBREAK, MEXICAN CHILDREN, YOUNG-CHILDREN
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
URI: http://discovery.ucl.ac.uk/id/eprint/76468
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