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Delayed pressure urticaria, objective evaluation of a variable disease using a dermographometer and assessment of treatment using colchicine

Lawlor, F; Black, AK; Ward, AM; Morris, R; Greaves, MW; (1989) Delayed pressure urticaria, objective evaluation of a variable disease using a dermographometer and assessment of treatment using colchicine. Br.J.Dermatol. , 120 (3) pp. 403-408.

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Abstract

A randomized double-blind placebo controlled trial of colchicine in the treatment of 13 patients with delayed pressure urticaria enabled us to assess some of the variables in this disorder. We have modified a previously described method of pressure testing using a calibrated dermographometer and shown a pressure induced papular dose response curve. Assessment of disease activity was based on the number of pressure weals which occurred, the size of delayed pressure induced papules using a dermographometer calibrated at 9.75 x 10(5) pascals for five separate time periods on the back and estimations of erythrocyte sedimentation rate and the acute phase protein levels. We have been unable to show a therapeutic effect using colchicine 0.5 mg bd for I week

Type: Article
Title: Delayed pressure urticaria, objective evaluation of a variable disease using a dermographometer and assessment of treatment using colchicine
Additional information: UI - 89228920DA - 19890620IS - 0007-0963LA - engPT - Clinical TrialPT - Journal ArticlePT - Randomized Controlled TrialCY - ENGLANDRN - 64-86-8 (Colchicine)SB - IM
Keywords: Adult, Clinical Trials, Colchicine, Comparative Study, Double-Blind Method, drug therapy, England, Female, Human, instrumentation, London, Male, Middle Age, pathology, Pressure, Random Allocation, Skin, Skin Tests, therapeutic use, Urticaria
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health Care
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Epidemiology and Health Care > Primary Care and Population Health
URI: http://discovery.ucl.ac.uk/id/eprint/75449
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