Gao, L;
Elwell, CE;
Kohl-Bareis, M;
Gramer, M;
Cooper, CE;
Leung, TS;
Tachtsidis, I;
(2011)
Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre.
In: LaManna, JC and Puchowicz, MA and Xu, K and Harrison, DK and Bruley, DF, (eds.)
Oxygen Transport to Tissue XXXII.
(pp. 15 - 20).
Springer Verlag: Berlin/ Heidelberg, Germany.
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Abstract
Resolving for changes in concentration of tissue chromophores in the human adult brain with near-infrared spectroscopy has generally been based on the assumption that optical scattering and pathlength remain constant. We have used a novel hybrid optical spectrometer that combines multi-distance frequency and broadband systems to investigate the changes in scattering and pathlength during a Valsalva manoeuvre in 8 adult volunteers. Results show a significant increase in the reduced scattering coefficient of 17% at 790nm and 850nm in 4 volunteers during the peak of the Valsalva. However, these scattering changes do not appear to significantly affect the differential pathlength factor and the tissue haemoglobin concentration measurements.
| Type: | Proceedings paper |
|---|---|
| Title: | Effects of Assuming Constant Optical Scattering on Haemoglobin Concentration Measurements Using NIRS during a Valsalva Manoeuvre |
| Event: | 37th Annual Meeting of the International Society on Oxygen Transport to Tissue (ISOTT) |
| Location: | Cleveland, OH, US |
| Dates: | 5 - 9 July, 2009 |
| ISBN-13: | 9781441977557 |
| Open access status: | An open access version is available from UCL Discovery |
| DOI: | 10.1007/978-1-4419-7756-4_3 |
| Publisher version: | http://dx.doi.org/10.1007/978-1-4419-7756-4_3 |
| Language: | English |
| Additional information: | © 2011 Springer Verlag. The original publication is available at www.springerlink.com |
| Keywords: | Near-infrared spectroscopy, frequency-domain, continuous-wave |
| UCL classification: | UCL UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences UCL > Provost and Vice Provost Offices > UCL BEAMS UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science UCL > Provost and Vice Provost Offices > UCL BEAMS > Faculty of Engineering Science > Dept of Med Phys and Biomedical Eng |
| URI: | https://discovery.ucl.ac.uk/id/eprint/73895 |
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