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Clinical trials and basic research: defining mechanisms and improving treatment in connective tissue disease

Rubin, LJ; Black, CM; Denton, CP; Seibold, JR; (2007) Clinical trials and basic research: defining mechanisms and improving treatment in connective tissue disease. In: ARTHRITIS RESEARCH & THERAPY. (pp. ? - ?). BIOMED CENTRAL LTD

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Abstract

Despite advances in elucidating the pathogenic factors responsible for its development, systemic sclerosis remains complex and poorly understood, and treatment options are limited. Multidisciplinary collaborative efforts are needed to better characterize clinical and prognostic parameters and to design and implement large- scale clinical trials in well defined populations with therapies that target potential disease modulators.

Type: Proceedings paper
Title: Clinical trials and basic research: defining mechanisms and improving treatment in connective tissue disease
Event: Symposium on Advances in Systemics Sclerosis and Connective Tissue Disease
Location: Athens, GREECE
Dates: 2006-04
DOI: 10.1186/ar2194
Keywords: PULMONARY ARTERIAL-HYPERTENSION, ENDOTHELIN-RECEPTOR ANTAGONIST, SYSTEMIC-SCLEROSIS, MATRIX METALLOPROTEINASES, BOSENTAN, SCLERODERMA, FIBROSIS
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Medical Sciences > Div of Medicine > Inflammation
URI: http://discovery.ucl.ac.uk/id/eprint/738371
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