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Thymosin beta 4 and Ac-SDKP: Tools to mend a broken heart

Rossdeutsch, A; Smart, N; Riley, PR; (2008) Thymosin beta 4 and Ac-SDKP: Tools to mend a broken heart. J MOL MED-JMM , 86 (1) 29 - 35. 10.1007/s00109-007-0243-9.

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Abstract

Thymosin beta 4 - an endogenously occurring 43 amino acid peptide - has recently been shown to possess cardioprotective properties in the setting of acute myocardial infarction. This review focuses on the reported mechanisms of action through which Thymosin beta 4 might accomplish this effect and the clinical prospects for its use as a therapeutic agent.

Type: Article
Title: Thymosin beta 4 and Ac-SDKP: Tools to mend a broken heart
DOI: 10.1007/s00109-007-0243-9
Keywords: thymosin beta 4, acute myocardial infarction, cardioprotective properties, INTEGRIN-LINKED KINASE, NF-KAPPA-B, ACTIN-SEQUESTERING PEPTIDE, ANGIOGENESIS IN-VITRO, HUMAN BLOOD-PLATELETS, MYOCARDIAL-INFARCTION, SIGNALING PATHWAY, TETRAPEPTIDE ACSDKP, ENDOTHELIAL-CELLS, VIVO
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > UCL GOS Institute of Child Health > ICH Developmental Neurosciences Prog
URI: http://discovery.ucl.ac.uk/id/eprint/73658
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