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3D DT-MRI using a reduced-FOV approach and saturation pulses.

Wang, JJ; Deichmann, R; Turner, R; Ordidge, R; (2004) 3D DT-MRI using a reduced-FOV approach and saturation pulses. Magn Reson Med , 51 (4) pp. 853-857. 10.1002/mrm.20012.

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Abstract

Diffusion tensor imaging (DTI) can provide vital insights into brain connectivity, and may become an important tool for the diagnosis and treatment of neurological disease. However, DTI's intrinsic low signal-to-noise ratio (SNR) and vulnerability to ghosting artifacts can result in poor image quality with low spatial resolution, which limits its clinical applications. In this study, a new double-shot EPI sequence (half-FOV EPI) with high spatial resolution was developed. This method enables DT measurements to be obtained with high isotropic spatial resolution and whole-brain coverage. To avoid ghosting artifacts, the data are combined in image space rather than in k-space.

Type: Article
Title: 3D DT-MRI using a reduced-FOV approach and saturation pulses.
Location: United States
DOI: 10.1002/mrm.20012
Keywords: Adult, Algorithms, Artifacts, Brain, Diffusion Magnetic Resonance Imaging, Echo-Planar Imaging, Humans, Image Enhancement, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Male, Phantoms, Imaging
UCL classification: UCL > School of Life and Medical Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences
UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology
UCL > School of BEAMS > Faculty of Engineering Science
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering
URI: http://discovery.ucl.ac.uk/id/eprint/72602
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