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3D DT-MRI Using a Reduced-FOV Approach and Saturation Pulses

Wang, J-J; Deichmann, R; Turner, R; Ordidge, R; (2004) 3D DT-MRI Using a Reduced-FOV Approach and Saturation Pulses. Magnetic Resonance in Medicine , 51 (4) 853 - 857. 10.1002/mrm.20012.

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Diffusion tensor imaging (DTI) can provide vital insights into brain connectivity, and may become an important tool for the diagnosis and treatment of neurological disease. However, DTI's intrinsic low signal-to-noise ratio (SNR) and vulnerability to ghosting artifacts can result in poor image quality with low spatial resolution, which limits its clinical applications. In this study, a new double-shot EPI sequence (half-FOV EPI) with high spatial resolution was developed. This method enables DT measurements to be obtained with high isotropic spatial resolution and whole-brain coverage. To avoid ghosting artifacts, the data are combined in image space rather than in k-space. © 2004 Wiley-Liss, Inc.

Type: Article
Title: 3D DT-MRI Using a Reduced-FOV Approach and Saturation Pulses
DOI: 10.1002/mrm.20012
UCL classification: UCL > School of Life and Medical Sciences > Faculty of Brain Sciences > Institute of Neurology
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering
URI: http://discovery.ucl.ac.uk/id/eprint/72602
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