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Tuberculosis and survival of HIV-infected individuals by time since seroconversion

Glynn, JR; Murray, J; Shearer, S; Sonnenberg, P; (2010) Tuberculosis and survival of HIV-infected individuals by time since seroconversion. AIDS , 24 (7) 1067 - 1069. 10.1097/QAD.0b013e328337b100.

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Abstract

In a cohort of 1950 HIV-positive men with known dates of HIV seroconversion, 399 developed tuberculosis. Mortality rates following tuberculosis were greatly increased (hazard ratio, adjusted for age at seroconversion, 4.7, 95% confidence interval 3.7-6.1), and this ratio was similar at different times following seroconversion. Overall mortality was similar to that in western seroconverter cohorts with much lower rates of tuberculosis, suggesting that tuberculosis is more a marker of HIV progression than a cause of it.

Type: Article
Title: Tuberculosis and survival of HIV-infected individuals by time since seroconversion
DOI: 10.1097/QAD.0b013e328337b100
Keywords: ACTIVE ANTIRETROVIRAL THERAPY, GOLD-MINERS, COHORT, ADULTS, DEATH, DURATION, DISEASE
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health > Infection and Population Health
URI: http://discovery.ucl.ac.uk/id/eprint/71935
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