UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

HIV prevalence and testing practices among tuberculosis cases in London: a missed opportunity for HIV diagnosis?

Rodger, AJ; Story, A; Fox, Z; Hayward, A; London TB Nurses Network, ; (2010) HIV prevalence and testing practices among tuberculosis cases in London: a missed opportunity for HIV diagnosis? THORAX , 65 (1) 63 - 69. 10.1136/thx.2009.122754.

Full text not available from this repository.

Abstract

Background: Universal testing for HIV in patients with tuberculosis (TB) has been advocated for over a decade. The aim of this study was to describe the prevalence and testing practices of HIV in TB centres in London.Methods: A cohort study was undertaken of all patients with TB in Greater London in 2003-4 (n = 1941). Logistic regression was used to assess factors affecting being offered and accepting testing and having a positive HIV result.Results: The overall known prevalence of HIV was 9.9% (193/1941). In those with a test result (including those diagnosed previously) it was 25.6%. Overall, 50.8% of patients aged >= 20 years without previous testing were offered HIV testing and, of these, 73% accepted. In multivariable analysis, factors associated with being HIV positive were age 20-49 years, black ethnicity and being born overseas. Those with smear-negative disease and with a poor understanding of English were significantly less likely to be offered HIV testing. Factors associated with refusal of an offered test were female gender or age >49 years. HIV status was not associated with smear status, drug resistance or death, but was associated with CNS disease (OR 1.8, 95% CI 1.0 to 3.0, p = 0.003).Conclusions: Nearly half the patients with TB in London in 2003-4 were not offered HIV testing. In those offered testing, uptake was high. Patients in higher risk groups were more likely to be offered testing but, even within the highest risk groups, testing was not universally offered. This represents a missed opportunity for diagnosing HIV in patients with TB in London.

Type: Article
Title: HIV prevalence and testing practices among tuberculosis cases in London: a missed opportunity for HIV diagnosis?
DOI: 10.1136/thx.2009.122754
Keywords: IMMUNODEFICIENCY-VIRUS-INFECTION, PERSONS AWARE, UNITED-STATES, RISK-FACTORS, TRANSMISSION, SETTINGS, THERAPY, ENGLAND, UNAWARE, AFRICAN
UCL classification: UCL > Provost and Vice Provost Offices
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute for Global Health > Infection and Population Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health
UCL > Provost and Vice Provost Offices > School of Life and Medical Sciences > Faculty of Pop Health Sciences > Institute of Epidemiology and Health > Epidemiology and Public Health
UCL > Provost and Vice Provost Offices > VP Health
UCL > Provost and Vice Provost Offices > VP Health > Clinical Research Support Centre
UCL > Provost and Vice Provost Offices > VP Health > Clinical Research Support Centre > Joint Research Office
URI: http://discovery.ucl.ac.uk/id/eprint/71431
Downloads since deposit
0Downloads
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item