Chatterjee, R; Deng, D; Pellerin, D; Todd-Pokropek, A; Neild, GH; Lees, WR; Rodeck, CH; (2008) Feasibility of dynamic 3-D color Doppler ultrasound for imaging penile vascular change in renal transplant patients with erectile dysfunction responding to sildenafil. ULTRASOUND MED BIOL , 34 (6) 885 - 891. 10.1016/j.ultrasmedbio.2007.11.013.
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Renal transplant recipients (RTRs) have a high incidence of erectile dysfunction (ED). Differentiation of penile vasculogenic impotence from other causes is important for treatment. Conventional 2-D color Doppler assessment after intracavernosal stimulant injection often fails to produce reliable results because of limited views by the cross-sectional imaging and the painful procedure. In comparison to the findings in three healthy volunteers, we determined cavernosal vascular hemodynamics in eight RTRs with ED before and after oral sildenafil by using live 3-D ultrasound and dynamic 3-D color Doppler. Results showed that, before sildenafil, penile arterial flow signals could only be reliably detected in one patient. After sildenafil, all had reliably detectable flow with grades II to III erection. Our data suggest that 3-D volumetric changes of the penis and its vasculature during erection can be studied by this technique and that this method could be useful for the evaluation of new drugs and therapeutic biofeedback. (E-mail: firstname.lastname@example.org) (c) 2008 World Federation for Ultrasound in Medicine & Biology.
|Title:||Feasibility of dynamic 3-D color Doppler ultrasound for imaging penile vascular change in renal transplant patients with erectile dysfunction responding to sildenafil|
|Keywords:||three-and four-dimensional imaging, ultrasonography, color Doppler, sildenafil, erectile dysfunction, renal transplant, PROSTATE-CANCER, POWER DOPPLER, 3-DIMENSIONAL ULTRASOUND, BODY PARTS, ECHOCARDIOGRAPHY, VISUALIZATION, RECIPIENTS, IMPOTENCE, TISSUE|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)|
UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute for Women's Health > Reproductive Medicine
UCL > School of BEAMS > Faculty of Engineering Science > Medical Physics and Bioengineering
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