UCL logo

UCL Discovery

UCL home » Library Services » Electronic resources » UCL Discovery

Corneal thickness determination and correlates in Singaporean schoolchildren

Tong, L; Saw, SM; Siak, JK; Gazzard, G; Tan, D; (2004) Corneal thickness determination and correlates in Singaporean schoolchildren. INVEST OPHTH VIS SCI , 45 (11) 4004 - 4009. 10.1167/iovs.04-0121.

Full text not available from this repository.


PURPOSE. To determine the central cornea thickness (CCT) in Singaporean children and to examine the possible relationship between intraocular pressure (IOP) and other biometric factors and CCT.METHODS. This was a cross-sectional study. The subjects (N = 652) were obtained from the Singapore Cohort Study of the Risk Factors for Myopia (SCORM). The subjects' ages ranged from 9 to 11 years. There were 485 Chinese, 92 Malayan, and 75 Asian Indian children. Measurement procedures included air-puff tonometry, noncontact slit lamp optical pachymetry, cycloplegic autorefraction, and autokeratometry.RESULTS. The mean CCT was 543.6 +/- 32.0 mum. Chinese children had thicker corneas than Malayan or Indian children (P = 0.002). The boys had thicker corneas than girls (P = 0.011), but the mean difference was only 6.4 mum. There was high correlation of CCT (r = 0.98) and IOP (r = 0.88) between right and left eyes. IOP was correlated with CCT (r = 0.45, P < 0.001). In a multiple linear regression model, each millimeter of mercury of IOP was associated with a CCT difference of 5.90 &mu;m (95% confidence interval [CI], 4.98-6.82). The radius of corneal curvature correlated with CCT (r = 0.19, P < 0.001). The following parameters were not significantly (P > 0.05) associated with CCT: age, family income, father's education, axial length, and spherical equivalent.CONCLUSIONS. The mean CCT in Singaporean children aged 9 to 11 years was 543.6 Am and showed ethnic and gender variation. CCT affected measured IOP and correlated weakly with corneal curvature. Compared with data in adults, a change in CCT was associated with a greater difference in measured IOP.

Type: Article
Title: Corneal thickness determination and correlates in Singaporean schoolchildren
DOI: 10.1167/iovs.04-0121
URI: http://discovery.ucl.ac.uk/id/eprint/66145
Downloads since deposit
Download activity - last month
Download activity - last 12 months
Downloads by country - last 12 months

Archive Staff Only

View Item View Item