Macchi, B; Caronti, B; Gremo, F; Torelli, S; Bonmassar, E; Lauro, GM; (1991) HTLV-I neurotropism. In vitro studies. Acta Neurol (Napoli) , 13 (2) 179 - 183.
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The human T cell leukemia lymphoma virus (HTLV-I) has been recently associated to neurological disorders. In order to investigate the interaction between this virus and the central nervous system, cells of neuroectodermic origin have been exposed to HTLV-I through an experimental in vitro model. The results revealed the presence of HTLV-I virus core protein p19 inside glial cells, after a short time exposure to a chronically infected donor cell line. This suggests a possible role of a lymphotropic retrovirus in neurological diseases.
|Title:||HTLV-I neurotropism. In vitro studies.|
|Keywords:||Animals, HTLV-I Infections, Humans, Nervous System Diseases|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Population Health Sciences > Institute of Child Health > Department of Neurosciences and Mental Health > ICH - Dubowitz Neuromuscular Centre|
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