Pickard, DCO; Bown, SG; Briggs, GM; Hall-Craggs, M; (2001) Interstitial laser photocoagulation of breast tumours. In: Birngruber, R and VandenBergh, H, (eds.) LASER-TISSUE INTERACTIONS, THERAPEUTIC APPLICATIONS, AND PHOTODYNAMIC THERAPY. (pp. 49 - 54). SPIE-INT SOC OPTICAL ENGINEERING
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Interstitial Laser Photocoagulation (ILP) is a method of destroying lesions in the center of solid organs without the need for open surgery. Under image guidance, up to four needles are inserted percutaneously into the tumor through which thin optic fibers are passed into the target lesion. Low power laser light from a semiconductor laser is delivered to gently coagulate the tissue. This 'dead tissue' is subsequently resorbed by the body's normal healing processes. Follow up is achieved with ultrasound imaging. One study is described for assessing ILP for benign fibroadenomas. Fibroadenomas were treated to assess how laser treated breast tissue healed in the long term and we have shown that the necrosed tissue is resorbed without complications over a period of months. Nevertheless, by following treated fibroadenomas (up to 35mm diameter) with ultrasound measurement at 3, 6 and 12 months, in 14 patients, only one lesion was still detectable 12 months after ILP. In appropriate cases, ILP could be an attractive option, as it leaves no scars and should not change the shape or size of the breast. If the present studies are successful, the plan is for a multi-center trial of minimally invasive, thermal ablation of breast cancers.
|Title:||Interstitial laser photocoagulation of breast tumours|
|Event:||Conference on Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy|
|Dates:||2001-06-18 - 2001-06-21|
|Keywords:||breast, benign tumour, interstitial laser photoeoagulation, ILP, fibroadenoma, treatment, ultrasound, THERAPY, CANCER|
|UCL classification:||UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Medicine (Division of)|
UCL > School of Life and Medical Sciences > Faculty of Medical Sciences > Surgery and Interventional Science (Division of) > Research Department of General Surgery
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